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El XXII Congreso De La Sociedad Italo Latinoamericana De Etnomedicina “Hernán Arguedas Soto” Fue Patrocinado Por

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El XXII Congreso De La Sociedad Italo Latinoamericana De Etnomedicina “Hernán Arguedas Soto” Fue Patrocinado Por El XXII Congreso de la Sociedad Italo Latinoamericana de Etnomedicina “Hernán Arguedas Soto” fue patrocinado por: y contó con el apoyo de: COORDINACIÓN GENERAL Silvia Quesada Mora, Ph.D. Dr. Luca Rastrelli Directora Dipartimento di Scienze Departamento de Bioquímica Farmaceutiche Escuela de Medicina, Università degli Studi di Salerno Universidad de Costa Rica Secretario General SILAE COMITÉ ORGANIZADOR Elvira Salas Hidalgo, Ph.D. Georgina Gómez Salas, M.Sc. Departamento de Bioquímica, Directora Escuela de Medicina Programa de Posgrado en Ciencias Universidad de Costa Rica Biomédicas Departamento de Bioquímica, Escuela de Medicina Laura Navarro Bolaños, Lic. Universidad de Costa Rica Departamento de Bioquímica, Escuela de Medicina Universidad de Costa Rica Yusselfy Alarcón Cabrera, Lic. Instituto Internacional en Conservación y Manejo de Vida Silvestre Gabriela Azofeifa Cordero, MSc. Universidad Nacional de Costa Rica Departamento de Bioquímica Escuela de Medicina Universidad de Costa Rica COMITÉ CIENTÍFICO LOCAL Ana Mercedes Pérez, Ph.D. Mildred García, M.Sc. Directora, Programa de Doctorado en Ciencias Departamento de Fisiología Coordinadora, Proceso de Investigación Escuela de Medicina Centro Nacional de Ciencia y Tecnología de Universidad de Costa Rica Alimentos (CITA) Universidad de Costa Rica Rosaura M. Romero, Ph.D. Directora Elizabeth Arnáez Serrano, M.Sc. Centro de Investigaciones en Productos Carrera Ingeniería en Biotecnología Naturales (CIPRONA) Escuela de Biología Universidad de Costa Rica Instituto Tecnológico de Costa Rica Cristina Herrera Arias, M.Sc. José Francisco Cicció Alberti, M.Sc. Investigadora Escuela de Química Instituto de Investigaciones Farmacéuticas Centro de Investigaciones en Productos (INIFAR) Naturales (CIPRONA) Facultad de Farmacia, Universidad de Costa Universidad de Costa Rica Rica Docente, Facultad de Farmacia, Max Chavarría, Ph.D. Universidad de Costa Rica Escuela de Química Centro de Investigaciones en Productos Ileana Moreira González, M.Sc. Naturales (CIPRONA) Directora Universidad de Costa Rica Escuela de Biología Instituto Tecnológico de Costa Rica Beatriz Badilla Baltodano, M.Sc. Catedrática Jubilada Luis Jorge Poveda Álvarez Facultad de Farmacia Curador Universidad de Costa Rica Herbario Juvenal Valerio Rodríguez Escuela de Ciencias Ambientales Franklin Binns, M.Sc. Universidad Nacional, Heredia Instituto de Investigaciones Farmacéuticas (INIFAR) Mirtha Navarro, Ph.D. Docente, Departamento de Farmacología Escuela de Química Facultad de Farmacia Universidad de Costa Rica Universidad de Costa Rica Víctor Castro Araya, Lic. Juan José Araya Barrantes, Ph.D. Centro de Investigaciones en Productos Escuela de Química Naturales (CIPRONA) Centro de Investigaciones en Productos Escuela de Química Naturales (CIPRONA) Universidad de Costa Rica Universidad de Costa Rica Mensaje de la Presidenta de SILAE Estimados amigos y colegas, Me gustaría brindarles una calurosa bienvenida en Costa Rica durante la XXII edición del Congreso SILAE. Desafortunadamente, debido a compromisos asumidos antes de la definición de la fecha de este congreso, no podré estar presente y disfrutar de su compañía, lo que es una pena. La realización de la 22ma edición del congreso SILAE en Costa Rica representa una oportunidad única de interactuar con investigadores de este país, el cual cuenta con una de las diversidades biológicas más ricas del planeta y a la vez con una amplia tradición de conservación biológica. El 25% del territorio costarricense se encuentra protegido, lo cual es un hermoso ejemplo a seguir!!!. Espero que todos puedan aprovechar esta oportunidad para estrechar los lazos de cooperación con este bello país. Me gustaría aprovechar el marco para felicitar a los organizadores y en especial a la profesora Silvia Quesada, nuestra tesorera de la SILAE, por la organización de este evento. Deseo a todos, un excelente congreso! Suzana Leitao Presidenta SILAE Bienvenidos Benvenuti Bemvindos Welcome Es un placer darles la más cordial bienvenida como participantes al XXII Congreso de la Sociedad Italo Latinoamericana de Etnomedicina Hernán Arguedas Soto y poder dirigirles unas palabras de bienvenida. Es un honor tener como invitados a renombrados investigadores que dictarán Conferencias Plenarias en los cinco ejes temáticos que abarcan el Congreso de la SILAE: Alimentos Funcionales y Nutrición; Etnobotánica/ Etnomedicina/ Antropología; Fitoquímica; Farmacología/Farmacognosia y Fitoterapia / Terapias alternativas. No fue sencillo realizar esta distribución dado que en las investigaciones muchos de los ejes se fusionan para dar origen a trabajos de investigación muy completos, lo que refleja un trabajo interdisciplinario en cada uno de nuestros países. Es importante recordar que este no es un Congreso Internacional tradicional en donde el principal objetivo es la presentación de nuestras investigaciones sino que pertenecemos a una Sociedad, a una gran familia, en la cual apoyarnos para fortalecer nuestra investigación y crear vínculos para realizar trabajos conjuntos, favorecer el crecimiento de nuestros investigadores jóvenes con cursos o pasantías en los distintos laboratorios y la posibilidad de divulgación de nuestras investigaciones. Si aún no pertenecen a la SILAE los insto a conocer todos los beneficios que aporta y a inscribirse en ella. Que este hermoso ambiente propicie muchas discusiones y relaciones amistosas, como base de nuevos proyectos en los distintos campos que abarca esta Sociedad y promueva el desarrollo personal y científico en cada uno de los participantes. Estoy segura que luego de este XXII Congreso de la SILAE, se adquirirá un impulso importante y afianzará su presencia en la región. Para su trabajo en el futuro les deseo lo mejor a ustedes y sus colaboradores. Silvia Quesada Coordinadora SILAE-UCR 2013 Recuerde que puede realizar la búsqueda de cualquier término o nombre de autor incluídos en este documento, utilizando la herramienta de búsqueda disponible en todos los programas para lectura de archivos PDF. Usualmente esta herramienta puede ser activada con las teclas Command + F en Mac, y Ctrl + F en Windows. Alimentos Funcionales y Nutrición Alimentos Funcionales y Nutrición Presentaciones Orales Alimentos Funcionales y Nutrición FOODOMICS: A NEW APPROACH TO INVESTIGATE FOOD IN THE POSTGENOMIC ERA Clara Ibáñez, Alberto Valdés, Carolina Simó, Miguel Herrero, Elena Ibáñez, Virginia García-Cañas, Alejandro Cifuentes Laboratory of Foodomics, CIAL (CSIC). Nicolas Cabrera 9, 28049 Madrid, Spain. The use of advanced “omics” tools in food science and nutrition allows investigating topics nowadays that were considered unapproachable few years ago, this trend has generated a new discipline defined for the first time by our group as “Foodomics” [1-3] (“Alimentómica” in Spanish). Safety, quality and bioactivity of foods and food ingredients are investigated in Foodomics through the application and integration of advanced omics technologies, including genomics, transcriptomics, proteomics and/or metabolomics. The main goals of Foodomics are to improve consumers’ well-being and knowledge [1-3]. A global Foodomics study performed by our group demonstrated the antiproliferative activity of different extracts from rosemary against colon cancer cells [4]. In the present work, we show a step forward in this long investigation in which a complete metabolomics study (combining results from LC-MS and CE-MS platforms) is carried out to corroborate the anti-proliferative effect of one of the main dietary polyphenols that was found in all the active rosemary extracts (i.e., carnosic acid). Moreover, the present work provides additional information on how this polyphenol from rosemary is able to modulate a specific metabolic pathway in the colon cancer cells (i.e., polyamines pathway), providing new evidences at molecular level on the antiproliferative effect of this type of compounds. REFERENCES: [1] Herrero, M., Simó, C., García-Cañas, V., Ibáñez, E., Cifuentes, A., Mass Spec. Rev. 31 (2012) 49–69. [2] Cifuentes, A., J. Chromatogr. A 1216, 7109-7110 (2009). [3] García-Cañas, V., Simó, C., Herrero, M., Ibáñez, E., Cifuentes, A., Anal. Chem. 84 (2012) 10150–10159 [4] Ibáñez, C., Valdés, A., García-Cañas, V., Simó, C., Celebier, M., Rocamora, L., Gómez, A., Herrero, M., Castro, M., Segura- Carretero, A., Ibáñez, E., Ferragut, J.A., Cifuentes A., J. Chromatogr. A 1248 (2012) 139-153 10 Alimentos Funcionales y Nutrición FUNCTIONAL FOODS AND BIOLOGICAL EFFECTS OF PHYTOMICRONUTRIMENTS Véronique Coxam Unité de Nutrition Humaine, UMR1019 (INRA / Université d’Auvergne), INRA Theix, 63122 Saint Genès Champanelle, France; [email protected] Prevention of chronic diseases through dietary means is especially challenging in technologically advanced societies. This is why nutritional science and development of food / food products adapted to the requirements of modern power ‘optimized’ functional foods provide a unique opportunity. Indeed, it has been recognised that, in addition to its vocation to cover the basic needs of the body, the human diet contains a complex array of naturally occurring bioactive molecules endowed with interesting protective properties which can delay the onset of diseases. In fact, this concept reflects the evolution of science from proper nutrition to avoid deficiencies, towards objectives of optimal nutrition. This approach meets on the one hand, dreams of researchers to solve health problems and, on the other hand, the aspirations of the consumer to be able to have food that would provide
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