BIOL 7020 A: Special Topics in Cell and Molecular Biology (Fall 2013; CRN: 81328)
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Section 2 Contribution of Science and Technology to Global Issues
Chapter 1 Progress in Science and Technology and Socioeconomic Changes Section 2 Contribution of Science and Technology to Global Issues From the end of the 19th century to the 20th century, science and technology has rapidly advanced. Chemical industry, electrical industry and heavy industry and so on emerged and we have advanced forward to ages of mass production and mass consumption, when goods could be transported in bulk to distant locations for a short period, as physical distribution, including railways, cars and airplanes, developed. This accompanied the mass disposal of goods and mass consumption of energy, highlighting the Chapter 1 risk of depletion of limited resources, global warming, the destruction of ecosystems and the crisis in the global environment. Science and technology that changed our lives were explained in Section 1 of this chapter, but as well as changing our lives in terms of key daily lifestyle elements, science and technology are also crucial to solve global issues such as climate change, natural resource depletion and energy. There are significant expectations as to how science and technology can contribute to solve global issues. This section addresses the social contribution of science and technology in Japan domestically and internationally. 1 Contribution to Global Warming Countermeasures ○ Global warming state Climate changes caused by global warming are Average global surface temperature (land + sea) anomaly one of the most urgent problems which the world faces. The Intergovernmental Panel on Climate Change (IPCC)1, awarded the Nobel Peace Prize Year in 2007, published the Synthesis Report of Fifth Changes in average global sea level Assessment Report in 2014. -
CRISPR-Cas9 a New Tool for Genome Editing.Pdf
CRICRICRISSPSPEPERERRCCCaasas9s99 AA ANe Ne Neww wT To Toool olf olf orf orGe rGe Gennonomomem eE eEd Editdiitinitngingg ByB JyBen Jyen Jneninferinfer iDofer Do uDodunduand,a nK, aeK,v eKivnei nvDi noD xoDzxoezxnez,n ea,n a,d na dMn dMa rMatirnati rnJti nJie nJkienkek A AK eAKy eK yEe xEyp xEepxrepimreimenriment enpt rpto rpdorudocudecudec dbe ydb Tyb hTye hT eEh xeEp xElpoxlrpoelrore’srre ’Gsr ’uGs iuGdieud ietdo et oB t ioBo ilBooilgooylgoygy 2 The Explorer’s Guide to Biology https://explorebiology.org/ CRISPR-Cas9 A New Tool for Genome Editing Jennifer Doudna, Kevin Doxzen, and Martin Jinek Jennifer Doudna Jennifer Doudna is a professor in the Departments of Molecular and Cell Biology and the Chemistry and Chemical Engineering at the University of California, Berkeley. For her studies on CRISPR-Cas9, Dr. Doudna has received several awards including the Breakthrough Prize in the Life Sciences, the Japan Prize, and the Canada Gairdner Award. She has been leading efforts to discuss ethical uses of genome editing technologies. Doudna teaches in Bio 1A, an introductory biology class at UC Berkeley. Kevin Doxzen Kevin Doxzen, a former graduate student with Jennifer Doudna, is a sci- ence communications specialist at the Innovative Genomics Institute, which is advancing genome engineering using CRISPR technologies. 3 Martin Jinek Martin Jinek, born in Czechoslovakia and a former postdoctoral fellow with Jennifer Doudna, is now an associate professor in the Department of Biochemistry at the University of Zurich. Jinek received the EMBL John Kendrew Young Scientist Award and the Friedrich Miescher Award of the Swiss Society for Molecular and Cellular Biosciences. -
Download This Issue As A
MICHAEL GERRARD ‘72 COLLEGE HONORS FIVE IS THE GURU OF DISTINGUISHED ALUMNI CLIMATE CHANGE LAW WITH JOHN JAY AWARDS Page 26 Page 18 Columbia College May/June 2011 TODAY Nobel Prize-winner Martin Chalfie works with College students in his laboratory. APassion for Science Members of the College’s science community discuss their groundbreaking research ’ll meet you for a I drink at the club...” Meet. Dine. Play. Take a seat at the newly renovated bar grill or fine dining room. See how membership in the Columbia Club could fit into your life. For more information or to apply, visit www.columbiaclub.org or call (212) 719-0380. The Columbia University Club of New York 15 West 43 St. New York, N Y 10036 Columbia’s SocialIntellectualCulturalRecreationalProfessional Resource in Midtown. Columbia College Today Contents 26 20 30 18 73 16 COVER STORY ALUMNI NEWS DEPARTMENTS 2 20 A PA SSION FOR SCIENCE 38 B OOKSHELF LETTERS TO THE Members of the College’s scientific community share Featured: N.C. Christopher EDITOR Couch ’76 takes a serious look their groundbreaking work; also, a look at “Frontiers at The Joker and his creator in 3 WITHIN THE FA MILY of Science,” the Core’s newest component. Jerry Robinson: Ambassador of By Ethan Rouen ’04J, ’11 Business Comics. 4 AROUND THE QU A DS 4 Reunion, Dean’s FEATURES 40 O BITU A RIES Day 2011 6 Class Day, 43 C L A SS NOTES JOHN JA Y AW A RDS DINNER FETES FIVE Commencement 2011 18 The College honored five alumni for their distinguished A LUMNI PROFILES 8 Senate Votes on ROTC professional achievements at a gala dinner in March. -
書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S. -
Greetings from Director of RIEM Greetings from Director of RIPM
Greetings from director of RIEM The Research Institute for Engineering Measurement (RIEM) has a lot of researchers and experts from mechanical engineering, applied physics, measurement and control, and information technology (number of staff: about 70). We have three important missions. The first mission is to contribute to international activities related to legal metrology and to steadily conduct legal metrology services such as type approval test of specified measuring instruments and inspection of verification standards used in local verification offices, in cooperation with the Ministry of Economy, Trade and Industry. The second is to develop, maintain, and smoothly disseminate national measurement standards for length, mass, and their related derived quantities. Dr. OTA Akihiro The third is to promote the advancement of high-precision measurement technology and data science technology on the basis of our measurement standards, and to connect their research outcomes to companies for future national and international businesses. We hope to promote research activities to solve social problems such as energy and environmental constraints and COVID-19 infection, and to create innovations that will contribute to industrial competitiveness. Greetings from director of RIPM According to the 5-year midterm plan of AIST which started in April 2020, the Research Institute for Physical Measurement (RIPM), which consists of twelve research groups with over 80 researchers, started new challenges to develop and disseminate the national measurement standards in the fields of electricity, time and frequency, temperature, and optical radiation – all of which underpin the industrial competitiveness, product reliability, and safety in our daily lives. In particular, the RIPM will contribute to cutting- edge research and development for measurement standards such as optical lattice clocks towards the redefinition of the second, and quantum current standards using single-electron pump devices for quantum metrology triangle experiments. -
Swedish Model of Developing Innovative Drugs: What Happened and Why?
Acta Scientific Pharmaceutical Sciences (ISSN: 2581-5423) Volume 4 Issue 1 January 2020 Short Communication Swedish Model of Developing Innovative Drugs: What Happened and Why? Jan Olof G Karlsson* Received: December 12, 2019 Division of Drug Research/Pharmacology, Linköping University, Linköping, Published: December 23, 2019 Sweden © All rights are reserved by Jan Olof G *Corresponding Author: Jan Olof G Karlsson, Division of Drug Research/ Karlsson. Pharmacology, Linköping University, Linköping, Sweden. DOI: 10.31080/ASPS.2020.04.0463 - cacious drugs. It has for example been an explosion in our un- American collaborator Sterling Winthrop wanted to add “physi- Still there are large medical needs that are not met with effi it came to the final formulation of Visipaque, Nycomed Imaging’s derstanding of cancer biology but our ability to translate these ological concentration of calcium ions” to it, apparently because it advances into therapies is poor [1]. To developing new drugs is, would sound god when promoting Visipaque. Almén together with a few other scientists realized that such a formulation would put theoretically as well as practically, integrity, creativity, engagement, patients, particularly during coronary angiography, in real danger however, far from an easy task. It demands scientific competence, responsibility and, not at least, critical thinking. - because of increased risk of ventricular fibrillation. The Manage - arguments but not Almén! Later on competitors argue but without cover and develop new drugs that met large medical needs, e.g., ment of Nycomed Imaging was ambivalent for Sterling Winthrop’s Before 1990, the Swedish pharma industry was efficient to dis any proof that Visipaque was more nephrotoxic than its forerun- terbutaline (Bricanyl), felodipin (Plendil), metoprolol (Seloken) ners. -
Lecture Program
EARL W. SUTHERLAND LECTURE EARL W. SUTHERLAND LECTURE The Earl W. Sutherland Lecture Series was established by the SPONSORED BY: Department of Molecular Physiology and Biophysics in 1997 DEPARTMENT OF MOLECULAR PHYSIOLOGY AND BIOPHYSICS to honor Dr. Sutherland, a former member of this department and winner of the 1971 Nobel Prize in Physiology or Medicine. This series highlights important advances in cell signaling. ROBERT J. LEFKOWITZ, MD NOBEL PRIZE IN CHEMISTRY, 2012 SPEAKERS IN THIS SERIES HAVE INCLUDED: SEVEN TRANSMEMBRANE RECEPTORS Edmond H. Fischer (1997) Alfred G. Gilman (1999) Ferid Murad (2001) Louis J. Ignarro (2003) MARCH 31, 2016 Paul Greengard (2007) 4:00 P.M. 208 LIGHT HALL Eric Kandel (2009) Roger Tsien (2011) Michael S. Brown (2013) 867-2923-Institution-Discovery Lecture Series-Lefkowitz-BK-CH.indd 1 3/11/16 9:39 AM EARL W. SUTHERLAND, 1915-1974 ROBERT J. LEFKOWITZ, MD JAMES B. DUKE PROFESSOR, Earl W. Sutherland grew up in Burlingame, Kansas, a small farming community DUKE UNIVERSITY MEDICAL CENTER that nourished his love for the outdoors and fishing, which he retained throughout INVESTIGATOR, HOWARD HUGHES MEDICAL INSTITUTE his life. He graduated from Washburn College in 1937 and then received his MEMBER, NATIONAL ACADEMY OF SCIENCES M.D. from Washington University School of Medicine in 1942. After serving as a MEMBER, INSTITUTE OF MEDICINE medical officer during World War II, he returned to Washington University to train NOBEL PRIZE IN CHEMISTRY, 2012 with Carl and Gerty Cori. During those years he was influenced by his interactions with such eminent scientists as Louis Leloir, Herman Kalckar, Severo Ochoa, Arthur Kornberg, Christian deDuve, Sidney Colowick, Edwin Krebs, Theodore Robert J. -
Passport to an International Career -True Globalism
Passport to an international career̶True globalism ● Maki KAWAI Professor at Graduate School of Frontier Sciences, The University of Tokyo; RIKEN The Nobel Prize in Chemistry 2010 was awarded jointly to United States, it is rare for one to earn one’s Ph.D. in the United Richard F. Heck, Akira Suzuki, and Ei-ichi Negishi for their con- States like Ei-ichi Negishi. Satoru Masamune left Japan to study tributions to the development of organic synthesis that is also at the University of California, Berkley in 1957 as a Fulbright important industrially. Since palladium-catalyzed cross coupling scholar, and later became professor at Massachusetts Institute of is an area in which Japan is strong and for which it had been Technology (MIT) nurturing many organic scientists. Hiroaki widely expected that someday someone would receive the award, Suga of the Department of Chemistry, School of Science, The I honor the three winners and at the same time appreciate having University of Tokyo, and Yukishige Ito of RIKEN, who is pres- the opportunity to learn of the achievements made by many ently working on glycotrilogy at Exploratory Research for researchers engaged in this area of study. It is well known that Advanced Technology (ERATO), have both studied at MIT’s many of the Nobel Prize winners pursue their research work in Masamune Laboratory. Kazuo Nakamoto (Professor Emeritus at the United States, and Japanese winners are no exception. Marquette University in the United States, deceased June 2011) Among the fifteen winners up to 2010, the five winners of Ei-ichi of infrared or Raman spectroscopies left for the United States in Negishi (Nobel Prize in Chemistry 2010), Osamu Shimomura 1958, and is famous for his editions of“ Infrared and Raman Spec- (Nobel Prize in Chemistry 2008), Yoichiro Nambu (Nobel Prize tra of Inorganic and Coordination Compounds,” with which I am in Physics 2008), Susumu Tonegawa (Nobel Prize in Physiology sure many of you are familiar. -
Dear Colleague, This Invitation Is Being Sent on Behalf of Prof
Dear colleague, On behalf of Prof. Fernand Marquis (San Diego State U., USA), Prof. Soteris Kalogirou (Cyprus U. of Technology, Cyprus), and Prof. Bernard Raveau (U. of Caen, France), co-chairs of the 2nd International Symposium on Solid State Chemistry for Applications and Sustainable Development in my capacity as President of SIPS 2020/2021, I am personally inviting you to participate as an author/speaker. This major symposium focuses on solid-state chemistry corresponds to the relationships occurring between the synthesis, structure, and physical-chemical properties of solid inorganic compounds (in most cases), leading to a final compound with optimized properties such as advances in the synthesis routes, design of materials for sustainable energy production, advanced characterization techniques and applications, etc. These and many others are among the topics of the symposium. This symposium will be held as part of the combined SIPS 2020/2021, an annual multidisciplinary summit, organized by the not-for-profit corporation FLOGEN Stars Outreach (www.flogen.org), which is dedicated to achieving sustainability through science and technology applied in various fields. It incorporates summit plenary lectures from well-known speakers that address the link between various domains in the pursuit of sustainable development, as well as specific scientific symposia featuring specialized presentations in a specific domain, with the same goals in mind. The symposium and overall summit are planned to be held in Phuket, Thailand from November 28th – December 2nd 2021. We have confirmed until now the participation of the following 9 Nobel Laureates: Prof. Dan Shechtman, Prof. Didier Queloz, Prof. M. Stanley Whittingham, Sir Konstantin Novoselov, Prof. -
2004 Albert Lasker Nomination Form
albert and mary lasker foundation 110 East 42nd Street Suite 1300 New York, ny 10017 November 3, 2003 tel 212 286-0222 fax 212 286-0924 Greetings: www.laskerfoundation.org james w. fordyce On behalf of the Albert and Mary Lasker Foundation, I invite you to submit a nomination Chairman neen hunt, ed.d. for the 2004 Albert Lasker Medical Research Awards. President mrs. anne b. fordyce The Awards will be offered in three categories: Basic Medical Research, Clinical Medical Vice President Research, and Special Achievement in Medical Science. This is the 59th year of these christopher w. brody Treasurer awards. Since the program was first established in 1944, 68 Lasker Laureates have later w. michael brown Secretary won Nobel Prizes. Additional information on previous Lasker Laureates can be found jordan u. gutterman, m.d. online at our web site http://www.laskerfoundation.org. Representative Albert Lasker Medical Research Awards Program Nominations that have been made in previous years may be updated and resubmitted in purnell w. choppin, m.d. accordance with the instructions on page 2 of this nomination booklet. daniel e. koshland, jr., ph.d. mrs. william mccormick blair, jr. the honorable mark o. hatfied Nominations should be received by the Foundation no later than February 2, 2004. Directors Emeritus A distinguished panel of jurors will select the scientists to be honored. The 2004 Albert Lasker Medical Research Awards will be presented at a luncheon ceremony given by the Foundation in New York City on Friday, October 1, 2004. Sincerely, Joseph L. Goldstein, M.D. Chairman, Awards Jury Albert Lasker Medical Research Awards ALBERT LASKER MEDICAL2004 RESEARCH AWARDS PURPOSE AND DESCRIPTION OF THE AWARDS The major purpose of these Awards is to recognize and honor individuals who have made signifi- cant contributions in basic or clinical research in diseases that are the main cause of death and disability. -
Earl W. Sutherland Lecture Earl W
EARL W. SUTHERLAND LECTURE EARL W. SUTHERLAND LECTURE The Earl W. Sutherland Lecture Series was established by the SPONSORED BY: Department of Molecular Physiology and Biophysics in 1997 DEPARTMENT OF MOLECULAR PHYSIOLOGY AND BIOPHYSICS to honor Dr. Sutherland, a former member of this department and winner of the 1971 Nobel Prize in Physiology or Medicine. This series highlights important advances in cell signaling. MICHAEL S. BROWN, M.D NOBEL LAUREATE IN PHYSIOLOGY OR MEDICINE 1985 SPEAKERS IN THIS SERIES HAVE INCLUDED: SCAP: ANATOMY OF A MEMBRANE STEROL SENSOR Edmond H. Fischer (1997) Alfred G. Gilman (1999) Ferid Murad (2001) Louis J. Ignarro (2003) APRIL 25, 2013 Paul Greengard (2007) 4:00 P.M. 208 LIGHT HALL Eric Kandel (2009) Roger Tsien (2011) FOR MORE INFORMATION, CONTACT: Department of Molecular Physiology & Biophysics 738 Ann and Roscoe Robinson Medical Research Building Vanderbilt University Medical Center Nashville, TN 37232-0615 Tel 615.322.7001 [email protected] EARL W. SUTHERLAND, 1915-1974 MICHAEL S. BROWN, M.D. REGENTAL PROFESSOR Earl W. Sutherland grew up in Burlingame, Kansas, a small farming community that nourished his love for the outdoors and fishing, which he retained throughout DIRECTOR OF THE JONSSON CENTER FOR MOLECULAR GENETICS UNIVERSITY OF TEXAS his life. He graduated from Washburn College in 1937 and then received his M.D. SOUTHWESTERN MEDICAL CENTER AT DALLAS from Washington University School of Medicine in 1942. After serving as a medi- NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE, 1985 cal officer during World War II, he returned to Washington University to train with MEMBER, NATIONAL ACADEMY OF SCIENCES Carl and Gerty Cori. -
Los Premios Nobel De Química
Los premios Nobel de Química MATERIAL RECOPILADO POR: DULCE MARÍA DE ANDRÉS CABRERIZO Los premios Nobel de Química El campo de la Química que más premios ha recibido es el de la Quí- mica Orgánica. Frederick Sanger es el único laurea- do que ganó el premio en dos oca- siones, en 1958 y 1980. Otros dos también ganaron premios Nobel en otros campos: Marie Curie (física en El Premio Nobel de Química es entregado anual- 1903, química en 1911) y Linus Carl mente por la Academia Sueca a científicos que so- bresalen por sus contribuciones en el campo de la Pauling (química en 1954, paz en Física. 1962). Seis mujeres han ganado el Es uno de los cinco premios Nobel establecidos en premio: Marie Curie, Irène Joliot- el testamento de Alfred Nobel, en 1895, y que son dados a todos aquellos individuos que realizan Curie (1935), Dorothy Crowfoot Ho- contribuciones notables en la Química, la Física, la dgkin (1964), Ada Yonath (2009) y Literatura, la Paz y la Fisiología o Medicina. Emmanuelle Charpentier y Jennifer Según el testamento de Nobel, este reconocimien- to es administrado directamente por la Fundación Doudna (2020) Nobel y concedido por un comité conformado por Ha habido ocho años en los que no cinco miembros que son elegidos por la Real Aca- demia Sueca de las Ciencias. se entregó el premio Nobel de Quí- El primer Premio Nobel de Química fue otorgado mica, en algunas ocasiones por de- en 1901 al holandés Jacobus Henricus van't Hoff. clararse desierto y en otras por la Cada destinatario recibe una medalla, un diploma y situación de guerra mundial y el exi- un premio económico que ha variado a lo largo de los años.