DOCSLIB.ORG

CRP-Ongoing Projects Data.Pdf

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
CRP-Ongoing Projects Data.Pdf Project Indian PI First Indian PI Last French PI First French PI last S.No. Title of the project Indian Institution City French Institution City No Name Name Name Name Studying the role of rpoN, the INRA Laboratoire des Castanet 4800- alternative sigma factor, in the Prof. Suvendra 1 Ray Tezpur University Tezpur Dr. Stéphane Genin Interactions Plantes Micro- Tolosan B1 pathogenicity of R. solanacearum, the Kumar organisms- Cedex causal agent of bacterial wilt in plants National Centre for Biological INSERM (Institut National de la Muscle SC self-renewal: A stressful Sciences, TIFR, Institute for 2 5003-1 Prof. Jyotsna Dhawan Bangalore Dr Ana FERREIRO Santé et la Recherche Paris matter? Stem Cell Biology and Médicale) Regenerative Medicine Advanced Computational Models to Indian Institute of Science Mohanpur, Institut de Recherches en 3 5004-1 Facilitate Solar Activity and Space Dr. Dibyendu Nandi Dr. Laurène JOUVE Toulouse Education and Research, Kolkata Astrophysique et Planétologie Weather Predictions Influence of the Resorcin[4]arene on Tiruchirappali 4 5005-1 Dr. R. Ramesh Bharathidasan University Dr. D. Sémeril Université de Strasbourg Strasbourg the Catalytic Outcomes , Tamil Nadu Design and synthesis of new C1‐ ECPM University of symmetric biaryl‐based ligands and Strasbourg, UMR 5 5005-2 Dr. Pradeep Kumar National Chemical Laboratory Pune Dr. Frédéric LEROUX Strasbourg catalysts and their evaluation in 7509/CNRS/ECPM – Chimie asymmetric catalytic reactions Moléculaire The Immuno-Psychiatry in South India Jawaharlal Institute of Study (IPS): Immunogenetic and INSERM U 942, Saint Louis 6 5103-1 Dr. Vir Singh Negi Postgraduate Medical Pondicherry Dr. Ryad Tamouza Paris Immuno-phenotype Characterization Hospital Education and Research of Major Psychoses TIFR National Centre for (CSGA) UMR- 7 5103-2 Olfactory Modulation of Insect Flight Prof. Gaiti Hasan Bangalore Dr Jean-François Ferveur Dijon Biological Sciences CNRS6265/INRA1324/ Genome-scale analysis of differential propensities of different chromosomal TIFR National Centre for 8 5103-3 Aswin Sai Narain Seshasayee Bangalore Marco Cosentino Lagomarsino UMR 7238 CNRS, UPMC Paris domains for horizontal gene insertion Biological Sciences in Escherichia coli Laboratoire des Symbioses Decipher the symbiotic program in 9 5103-4 Dr. Maitrayee DasGupta University of Calcutta Kolkata Dr. Fabienne Cartieaux Tropicales & Montpellier tropical legumes Méditerranéennes (IRD) INSA Toulouse / Laboratoire Magnetic nanoparticles for Toulouse 10 5104-1 Varsha BANERJEE Indian Institute of Technology Delhi Julian CARREY de Physique et Chimie des hyperthermia and spintronics cedex Nano-Objets SELF-SIMILAR OPTICAL PATTERNS IN UMR 6303 CNRS, Université de 11 5104-2 Prof. K. Porsezian Pondicherry University Pondicherry Prof. Ph. Grelu Dijon Cedex NONLINEAR MEDIA Bourgogne Ecole Nationale Supérieure de Glycochemical Studies on Indian Institute of Science 12 5105-1 SRINIVAS HOTHA Pune THIERRY BENVEGNU Chimie de Rennes – UMR CNRS Rennes Mycobacterial Arabinomycolate Education and Research 6226 Molybdenum-containing enzymes: Indian Association for Aix-Marseille Université, ISM2 13 5105-2 bioinspired peptidic catalysts for CO2 Surajit SINHA Kolkata REGLIER Marius Marseille Cultivation of Science IACS UMR CNRS reduction sp3 C-H Bond Activation with Ruthenium(II) Catalysts: Application to CSIR-Indian Institute of 14 5105-4 Dr. G. V. M. Sharma Hyderabad Dr. Christian Bruneau Université de Rennes 1 Rennes the Synthesis of Aliphatic N- Chemical Technology Heterocyclic Natural Products Synthesis of Photocatalytic Porous Institut Européen des Indian Institute of Technology- 15 5108-1 Silicon-Containing Nitride and Dr. N.V Ravi Kumar Chennai Dr. Samuel Bernard Membranes (IEM UMR 5635 Montpellier Madras Oxynitride Nanocomposites CNRS) Survey of soil-Si pools and contribution University of Agricultural CEREGE‐Université d’Aix‐ 16 5109-1 of Si fertilization in a sustainable rice Dr N.B. Prakash Bangalore Dr J.D. Meunier Marseille Sciences Marseille III cultivation in South India Molecular study of RH gene variants in National Institute of Inserm U1078 Etablissement 17 5203-1 Dr. Swati Kulkarni Mumbai Dr. Yann FICHOU Brest Cedex 2 Indians Immunohaematology Français du Sang Insights on protein structural and Prof. Dr. G Alexandre 18 5203-2 Srinivasan Indian Institute of Science Bangalore Brevern Université Paris Diderot Paris evolutionary dynamics Narayanaswamy de Host-Virus Interactions and INSERM (Institut National de la Translational Health Science Lacroix- 19 5203-3 Antibody Therapy for Japanese Dr Manjula Kalia Faridabad Dr Sebastien Santé Et de la Recherche Paris and Technology Institute Desmazes Encephalitis Médicale) Novel inhibitors of NHEJ against Dr. Sathees C. 20 5203-4 Raghavan Indian Institute of Science Bangalore Dr.Jean-Baptiste CHARBONNIER CEA Saclay Gif-s-Yvette resistant tumour cells Raghavan Characterisation of factors that determine the balance between Dr. Desirazu Fontenay aux 21 5203-5 Rao Indian Institute of Science Bangalore Dr J. Pablo Radicella CEA-Fontenay aux Roses genomic integrity and diversity in Narasimha Roses Helicobacter pylori Monomode and multimode phase Greater 22 5204-1 sensitive Dr.Rupamanjari GHOSH Shiv Nadar University Dr.Fabien Bretenaker Laboratoire Aimé Cotton-CNRS Orsay Noida amplification and light storage Radio properties of clusters and galaxy Inter University Centre for Saint Genis 23 5204-2 Prof. Joydeep Bagchi Pune Dr.Bruno Guiderdoni Observatoire de Lyon- CRAL lenses Astronomy and Astrophysics Laval MODELLING PLASMA INSTABILITIES Prof.HITENDRA UMR 7345 du CNRS / Aix 24 5204-3 MALIK Indian Institute of Technology Delhi Prof.Fabrice DOVEIL Marseille AND TRANSPORT IN A HALL THRUSTER KUMAR Marseille Université Tata Institute of Fundamental 25 5204-4 Holography and its Applications Prof.Sandip Trivedi mumbai Dr. Nick Halmagyi UPMC, Sorbonne Universités Paris Research CNRS-University of Poitiers- 26 5208-1 Plasticity of covalent nanoparticles Prof. Umesh V. Waghmare Indian Institute of Science Bangalore Dr. Laurent Pizzagalli Futuroscope ISAE ENSMA Novel nanocatalysts synthesis guided Tata Institute of Fundamental CNRS UMR, Université of Lille Villeneuve 27 5208-2 Prof.Vivek Polshettiwar mumbai Prof. Olivier Lafon by DNP NMR Research 1 d’Ascq International Institute of Large-Scale Loss-based Learning via 28 5302-1 Prof. C V Jawahar Information Technology Hyderabad Prof. Cordelia Schmid INRIA Grenoble Energy Minimization Hyderabad Deciphering the role of Mycobacterium tuberculosis Dr. Vinay National Institute of Place Eugène 29 5303-1 Nandicoori New Delhi Dr. Virginie Molle Université Montpellier 2, Serine/Threonine protein phosphatase Kumar Immunology Bataillon PstP Original biocompatible phosphorus Central Drug Research CNRS - UPR8241 Laboratoire 30 5303-2 dendrimers as a new strategy to tackle Prof. Kishore K Srivastva Lucknow Dr. Anne-Marie Caminade Toulouse Institute de Chimie de Coordination pulmonary tuberculosis Theoretical studies on ultra‐cold Indian Institute of Science CNRS -UMR7538 Laboratoire 31 5304-1 Prof. Rejish Nath Pune Prof. Paolo Pedri Villetaneuse Dipolar Gases Education and Research Pune de Physique des Lasers Symmetries and dynamics: worldsheet CEA – Saclay Institut de Orme des 32 5304-2 Prof. Debashis Ghoshal Jawaharlal Nehru University New Delhi Prof. Ruben Minasian and spacetime Physique Théorique merisiers Quantum transport in 2D van der Indian Institute of Science, 33 5304-3 Waals heterostructures based on Dr. Aveek Bid Bangalore Dr. Vincent Bouchiat Neel Institute CNRS-Grenoble Grenoble Bangalore graphene and Boron Nitride ECPM-Chimie Moleculaire Axially chiral biaryls from C-H Indian Institute of Chemical 34 5305-1 Dr. K Rajender Reddy Hyderabad Dr. Françoise Colobert ;Université de Strasbourg, Strasbourg activation & radicals Technology Tarnaka UMR 7509/CNRS/ECPM Advanced time-domain integration 35 5307-1 schemes for the simulation of Earth and Prof. Binod Sreenivasan Indian Institute of Science Bangalore Dr. Alexandre Fournier Institut de Physique du Globe Paris planetary core dynamics Jawaharlal Nehru Centre for Université Paris Diderot – Magnetism of self-organized structures 36 5308-1 Dr. Shobhana Narasimhan Advanced Scientific Research Bangalore Dr. Sylvie C Rousset Paris 7, MPQ – UMR CNRS Paris at surfaces 7162 A comparative Systems Biology 5300- Approach for Understanding Université de Rouen, IRIB- Mont Saint- 37 Dr. R.G. Centre for Bioinformtion Tumkur Dr. Azeddine Driouich B1 Desiccation Tolerance in Forage Sharathchandra PRIMACEN-IBiSA Aignan Grasses and Selaginella sps. Sums of integers: Fourier, Prof. The Institute Of Mathematical Institut Mathématique de 38 5401-1 Ramachandran Chennai Prof. Jean-Marc Deshouillers Talence combinatorics, computation Balasubramanian Sciences Bordeaux Pathogenic Aspergillus: Interaction Aravind Medical Research 39 5403-1 Dr. Lalitha Prajna Madurai Prof. Jean-Paul Latgé Institut Pasteur Paris with innate immune cells Foundation LORIC: LOng-Range Interactions in Prof. Sadiqali 40 5404-1 Rangwala Raman Research Institute Bangalore Dr. Olivier Dulieu Laboratoire Aimé Cotton Orsay ultraCold gases Abbas Saha Institute of Nuclear 41 5404-2 Glimpses of New Physics Prof. Gautam Bhattacharyya Kolkata Dr. Emilian Dudas Ecole Polytechnique Palaiseau Physics H2 evolution: cheap catalysts for noble Indian Association For The 42 5405-1 Prof. Abhishek Dey Kolkata Dr. Vincent Artero CEA Centre De Grenoble Grenoble task Cultivation Of Science Understanding mechanical size effects 43 5408-1 in metallic
Load more

Recommended publications
  • Scheme of Instruction 2018-19
    Scheme of Instruction 2018-19 Contents A. Scheme of Instruction Course Page No. Prefix Preface 3 I Division of Biological Sciences Preface 6 Integrated Ph D Programme in Biological Sciences DB 7 Biochemistry BC 10 Ecological Sciences EC 13 Molecular Biophysics MB 15 Microbiology and Cell Biology MC 20 Molecular Reproduction, Development and Genetics RD 24 Neuroscience NS 26 II Division of Chemical Sciences Preface 28 Integrated Ph D Programme in Chemical Sciences CD 29 Inorganic and Physical Chemistry IP 34 Materials Research MR 38 Organic Chemistry OC 41 Solid State and Structural Chemistry SS 44 III Division of Physical and Mathematical Sciences Preface 47 Instrumentation and Applied Physics IN 48 Mathematics MA 55 Astronomy and Astrophysics AA 69 Physics and Integrated Ph D in Physical Sciences PH 70 High Energy Physics HE 84 IV Division of Electrical Sciences Preface 89 Core requirements for M Tech Degree Programmes M Tech Degree - Computer Science and Engineering M Tech Degree - Telecommunications M Tech Degree – Signal Processing M Tech Degree – Microelectronics Systems M Tech Degree – Electrical Engineering M Tech Degree – Systems Science and Automation M Tech Degree – Electronics Systems Engineering Computer Science and Automation Intelligent Systems and Automation Communication Systems 1 Electronic Devices, Circuits and Technology Power Energy Systems High Voltage and Insulation Systems Electronics and Power Drives Photonic Device Electromagnetics, Microwaves and Antennas Signal Processing, Acoustics and Bioengineering Dissertation
    [Show full text]
  • BRCA1 and BRCA2 Germline Mutation Analysis Among Indian
    BRCA1 and BRCA2 mutations in India 415 BRCA1 and BRCA2 germline mutation analysis among Indian women from south India: identifi cation of four novel mutations and high-frequency occurrence of 185delAG mutation KANNAN VAIDYANATHAN1,#, SMITA LAKHOTIA1,#, H M RAVISHANKAR1,#, UMAIRA TABASSUM2, GEETASHREE MUKHERJEE2,* and KUMARAVEL SOMASUNDARAM1,* 1Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560 012, India 2Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore 560 068, India #Contributed equally *Corresponding author (Fax, 91-80-23602697; Email, [email protected]) Mutations in the BRCA1 and BRCA2 genes profoundly increase the risk of developing breast and/or ovarian cancer among women. To explore the contribution of BRCA1 and BRCA2 mutations in the development of hereditary breast cancer among Indian women, we carried out mutation analysis of the BRCA1 and BRCA2 genes in 61 breast or ovarian cancer patients from south India with a positive family history of breast and/or ovarian cancer. Mutation analysis was carried out using conformation-sensitive gel electrophoresis (CSGE) followed by sequencing. Mutations were identifi ed in 17 patients (28.0%); 15 (24.6%) had BRCA1 mutations and two (3.28%) had BRCA2 mutations. While no specifi c association between BRCA1 or BRCA2 mutations with cancer type was seen, mutations were more often seen in families with ovarian cancer. While 40% (4/10) and 30.8% (4/12) of families with ovarian or breast and ovarian cancer had mutations, only 23.1% (9/39) of families with breast cancer carried mutations in the BRCA1 and BRCA2 genes. In addition, while BRCA1 mutations were found in all age groups, BRCA2 mutations were found only in the age group of ≤40 years.
    [Show full text]
  • Creating an Effective Platform for Communication and Exchange
    COLLABORATION Creating an effective platform for communication and exchange KNOWLEDGE INTERCHANGE COMMUNICATION NETWORKING ADVANCEMENT The 2013 Annual Report of the Society for Neuro-Oncology Society for NeuroOncology This Annual Report covers the SNO 2013 fiscal year, from July 1st, 2012 through June 30, 2013. INTERCHANGE COLLABORATION COMMUNICATION EXCHANGE PERSPECTIVES A Message from the President INTERCHANGE Dear Colleagues and Friends, As the outgoing President, I am happy to share with you I would like to acknowledge some of the COLLABORATION some of the Society’s accomplishments and endeavors individuals who have contributed to the success of our during my tenure. To begin with, SNO continues to grow Society and by extension furthered the development COMMUNICATION with an overall increase in membership of 11% since of neuro-oncology as a field. First, much appreciation October 2012, with current membership now approaching goes to SNO Foundation members Mark Gilbert 1500 and representation from 42 countries. (chair), Mitchel Berger, Susan Chang and Victor Levin I am likewise happy to share that the impact factor of and members of the Partners Advisory Council for the Society’s official journal,Neuro-Oncology , continues their continued support and guidance as the Society to rise, now standing at 6.1, solidifying its reputation as continues to grow. I would also like to recognize the EXCHANGE the leading journal in the field. Its success is, in large part, members of the Board of Directors for their willingness due to the dedication of the editor-in-chief, W K Alfred to represent the diverse disciplines of the neuro- Yung who completes his successful tenure at the end of oncology community and for their input into critical PERSPECTIVES this year.
    [Show full text]
  • Elucidating the Cancer-Specific Genetic Alteration Spectrum of Glioblastoma Derived Cell Lines from Whole Exome and RNA Sequencing
    www.impactjournals.com/oncotarget/ Oncotarget, Vol. 6, No. 41 Elucidating the cancer-specific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing Vikas Patil1,*, Jagriti Pal1,* and Kumaravel Somasundaram1 1 Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India * These authors have contributed equally to this work Correspondence to: Kumaravel Somasundaram, email: [email protected] Keywords: glioblastoma, exome & RNA sequencing, cancer-specific mutations, gene fusions, RNA editing Received: May 03, 2015 Accepted: October 05, 2015 Published: October 19, 2015 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ABSTRACT Cell lines derived from tumor tissues have been used as a valuable system to study gene regulation and cancer development. Comprehensive characterization of the genetic background of cell lines could provide clues on novel genes responsible for carcinogenesis and help in choosing cell lines for particular studies. Here, we have carried out whole exome and RNA sequencing of commonly used glioblastoma (GBM) cell lines (U87, T98G, LN229, U343, U373 and LN18) to unearth single nucleotide variations (SNVs), indels, differential gene expression, gene fusions and RNA editing events. We obtained an average of 41,071 SNVs out of which 1,594 (3.88%) were potentially cancer-specific. The cell lines showed frequent SNVs and indels in some of the genes that are known to be altered in GBM- EGFR, TP53, PTEN, SPTA1 and NF1. Chromatin modifying genes- ATRX, MLL3, MLL4, SETD2 and SRCAP also showed alterations.
    [Show full text]
  • Awards Galore at DBT Foundation Day
    Awards galore at DBT Foundation Day 10 April 2007 | News Image not found or type unknown Awards galore at DBT Foundation Day On March 12, 2007, a series of awards were announced to honor researchers, scientists working in the sciences arena. The Distinguished Biotechnologist Award for the year 2006 has been conferred on Prof. TP Singh for his outstanding contributions in structural biology. Prof. TP Singh headed the Biophysics Department at the All India Institute of Medical Sciences, New Delhi during 1986–August 2006. He obtained his PhD from the Indian Institute of Science, Bangalore in 1975 on structure–function studies of analgesic/anti-inflammatory agents. He has made original and novel contributions to the structural studies of proteins and implemented a strong program on structure-based rational drug design. Significantly, Prof. TP Singh has developed a new program on Clinical Proteomics at AIIMS in collaboration with other faculty members to characterize all the proteins that are expressed during various patho/physiological conditions. His group has already determined more than 50 structures of proteins and their complexes under this program. Dr Manju Sharma, former secretary, DBT, has been honored with the National Award for Senior Woman Bioscientist for the year 2006 in recognition of her vision and incessant efforts in shaping and steering research in biotechnology and new biology and for applying research results for the benefit of the society in the country. The National Award for Young Women Bioscientists for the year 2006 was conferred on Dr Gagandeep Kang, CMC, Vellore and Dr Ramanathan Sowdhamini, NCBS, Bangalore. Dr Gagandeep Kang has been honored for her significant contributions on rotaviral diarrhoeal diseases in children particularly on molecular epidemiology.
    [Show full text]
  • Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3Rd Edition)
    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation Klionsky, Daniel J., et al. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition).” Autophagy, vol. 12, no. 1, Jan. 2016, pp. 1–222. As Published http://dx.doi.org/10.1080/15548627.2015.1100356 Publisher Informa UK Limited Version Author's final manuscript Citable link http://hdl.handle.net/1721.1/116122 Terms of Use Creative Commons Attribution-Noncommercial-Share Alike Detailed Terms http://creativecommons.org/licenses/by-nc-sa/4.0/ AUTOPHAGY 2016, VOL. 12, NO. 1, 1–222 http://dx.doi.org/10.1080/15548627.2015.1100356 EDITORIAL Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J Klionsky1745,1749*, Kotb Abdelmohsen840, Akihisa Abe1237, Md Joynal Abedin1762, Hagai Abeliovich425, Abraham Acevedo Arozena789, Hiroaki Adachi1800, Christopher M Adams1669, Peter D Adams57, Khosrow Adeli1981, Peter J Adhihetty1625, Sharon G Adler700, Galila Agam67, Rajesh Agarwal1587, Manish K Aghi1537, Maria Agnello1826, Patrizia Agostinis664, Patricia V Aguilar1960, Julio Aguirre-Ghiso784,786, Edoardo M Airoldi89,422, Slimane Ait-Si-Ali1376, Takahiko Akematsu2010, Emmanuel T Akporiaye1097, Mohamed Al-Rubeai1394, Guillermo M Albaiceta1294, Chris Albanese363, Diego Albani561, Matthew L Albert517, Jesus Aldudo128, Hana Algul€ 1164, Mehrdad Alirezaei1198, Iraide
    [Show full text]
  • Current Excitements in Biochemistry and Molecular Biology for Agriculture and Medicine
    14th FAOBMB Congress and 84th Annual Meeting of SBC (I) Current Excitements in Biochemistry and Molecular Biology for Agriculture and Medicine Centre for Cellular and Molecular Biology, Hyderabad, India 27 – 30 November 2015 Programme Time (h) Day 1; Friday, 27 November 2015 11.00 - 13.00 Registration 12.30 - 13.30 Lunch 13.30 – 14.00 Inauguration 14.00 – 14.05 Announcement of President Elect, FAOBMB Plenary Lecture 1: Kanury V S Rao, India (Takashi Murachi Memorial Lecture) Deciphering the host-pathogen interplay in human macrophages infected with 14.05 - 14.45 Mycobacterium tuberculosis Chairperson: 14.45 - 15.25 Kiyoshi Fukui, Japan Plenary Lecture 2: Shubha Tole, India (Kunio Yagi Lecture) Towards a Blueprint for Building the Brain 15.25 - 15.55 Tea/Coffee Protein Folding and Disease Developmental Biology Epigenetics and miRNA 16.00 - 18.00 Chairperson: Masatsune Kainosho, Japan Chairperson: Polani B. Seshagiri, India Chairperson: K. Satyamoorthy, India L S. Shashidhara, India Manajit Hayer-Hartl, Germany Rakesh K. Mishra, India A comparative genomic analysis of targets of 16.00 - 16.30 The complex chaperone machineries for the Functional Compartmentalization of the Hox protein Ultrabithorax amongst distant folding and assembly of RuBisCO Genome and Epigenetic Regulation of Genes insect species: new insights into evolution of halteres in Drosophila Subramaniam Ganesh, India Tapas Kundu, India Kunihiro Kuwajima, Japan 16.30 - 17.00 Mitochondrial homeostasis and Lysine Acetylation and Arginine Methylation of The problem of protein folding
    [Show full text]
  • A Ten-Microrna Expression Signature Predicts Survival in Glioblastoma
    A Ten-microRNA Expression Signature Predicts Survival in Glioblastoma Sujaya Srinivasan, Irene Rosita Pia Patric, Kumaravel Somasundaram* Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, Karnataka, India Abstract Glioblastoma (GBM) is the most common and aggressive primary brain tumor with very poor patient median survival. To identify a microRNA (miRNA) expression signature that can predict GBM patient survival, we analyzed the miRNA expression data of GBM patients (n = 222) derived from The Cancer Genome Atlas (TCGA) dataset. We divided the patients randomly into training and testing sets with equal number in each group. We identified 10 significant miRNAs using Cox regression analysis on the training set and formulated a risk score based on the expression signature of these miRNAs that segregated the patients into high and low risk groups with significantly different survival times (hazard ratio [HR] = 2.4; 95% CI = 1.4–3.8; p,0.0001). Of these 10 miRNAs, 7 were found to be risky miRNAs and 3 were found to be protective. This signature was independently validated in the testing set (HR = 1.7; 95% CI = 1.1–2.8; p = 0.002). GBM patients with high risk scores had overall poor survival compared to the patients with low risk scores. Overall survival among the entire patient set was 35.0% at 2 years, 21.5% at 3 years, 18.5% at 4 years and 11.8% at 5 years in the low risk group, versus 11.0%, 5.5%, 0.0 and 0.0% respectively in the high risk group (HR = 2.0; 95% CI = 1.4–2.8; p,0.0001).
    [Show full text]
  • Book Download
    SOCIETY OF BIOLOGICAL CHEMISTS (INDIA) (1930 – 2011) 1 TABLE OF CONTENTS 1. Goals and activities of SBC(I) 2. Rules and Bye-laws of SBC(I) 3. Past Presidents, Secretaries, Treasurers (with tenure) 4. “Reminiscences on the development of the Society of Biological Chemists (India): a personal perspective” by Prof. N. Appaji Rao 5. “Growth of Biochemistry in India” by Prof. G. Padmanaban 6. Current office bearers 7. Current Executive Committee Members 8. Office staff 9. Past meeting venues of SBC(I) 10. SBC(I) awards, criteria and procedure for applying 11. SBC(I) awardees 12. Current list of life members with address 13. Acknowledgments 2 GOALS AND ACTIVITIES OF SBC(I) To meet a long felt need of scientists working in the discipline of biological chemistry " The Society Of Biological Chemists (India)" was founded in 1930, with its Head Quarters at Indian Institute of Science, Bangalore. It was registered under the Societies Act in the then princely state of Mysore and the memorandum of registration was signed by the late Profs. V. Subramanian, V. N. Patwardhan and C. V. Natarajan, who were leading personalities in the scientific firmament during that period. The Society played a crucial role during the Second World War by advising the Government on the utilization of indigenous biomaterials as food substitutes, drugs and tonics, on the industrial and agricultural waste utilization and on management of water resources. The other areas of vital interest to the Society in the early years were nutrition, proteins, enzymes, applied microbiology, preventive medicines and the development of high quality proteins from indigenous plant sources.
    [Show full text]
  • Activation of Multiple Signalling Pathways by P152lp53 Mutant Reveals New Gain-Of-Function Implicating Tumorigenesis
    bioRxiv preprint doi: https://doi.org/10.1101/475293; this version posted November 20, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis Siddharth Singh1*, Manoj Kumar1*&, Sanjeev Kumar2*, Shrinka Sen1, Pawan Upadhyay3, Naveen M2, Vivek S. Tomar 4, Amit Dutt3 and Tapas K. Kundu1 1Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru-560 064, India 2BioCOS Life Sciences Pvt. Ltd. Bengaluru, India 3 Integrated Cancer Genomics Lab, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Center, Navi Mumbai, India 4Department of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru-560 012, India. & Present address: School of Biological and Environmental Sciences,Faculty of Basic Sciences, Shoolini University, Solan, Himachal Pradesh, India *Authors contributed equally to this manuscript Conflict of interest: The authors declare no potential conflicts of interest. Significance: This study for the first time carried out extensive biochemical and functional characterization of P152Lp53 and established it as a new Gain-of-function mutant which is conformationally altered. Corresponding author: Prof. Tapas K. Kundu, Transcription and Disease Laboratory, Molecular and Genetics Unit, JNCASR, Jakkur P.O., Bengaluru-560064, India. Ph: 91-80-22082840/2841 Email: [email protected] Running Title: A Gain-of-function mutant p53 (P152L) Keywords: DNA Binding, p53 tetramerization, P152L, Tumor suppressor, Carcinogenesis 1 bioRxiv preprint doi: https://doi.org/10.1101/475293; this version posted November 20, 2018.
    [Show full text]
  • 37Th IACR Convention
    37th IACR Convention From Cancer Biology to Precision Oncology: Challenges and Considerations Jointly Organized by Indian Association of Cancer Research & Bose Institute, National Institute of Biomedical Genomics, Indian Statistical Institute, Indian Institute of Chemical Biology, IIT-KGP, IPGMR, Saha Institute of Nuclear Physics, IISER-Kolkata, Chittaranjan National Cancer Institute, Saroj Gupta Cancer Centre, Burdwan University, University of Calcutta 23rd- 25th February, 2018, Bose Institute, Unified Academic Campus, EN block, Salt Lake, Kolkata Programme 23rd February, 2018 08.30 am-09.30 am Registration 09.30 am-10.00 am Inauguration (Auditorium) SESSION 1 Chair: Prof. Partha P. Majumder 10:00am - 11:00 am IACR Oration & Institute Day Address of the National Institute of Biomedical Genomics, Kalyani Using Genomics to Inform Care of Patients with Cancer Peter Campbell 11:00am-11:30am Mapp Tea Break SESSION 2 Chair: Prof. Siddhartha Roy and Prof. Samit Chattopadhyay 11:30am – 11:50am INOVATe: a step closer to precision treatment for women with epithelial ovarian cancer Anna deFazio 1 11:50am -12:10 pm Genetic landscape of Indian gliomas: Defective neuroactive ligand-receptor interaction pathway identifies glioblastoma with poor survival Kumaravel Somasundaram 12:10pm-12:30pm Axonal Guidance Proteins in Tumorigenesis: Role of Genetic Status of KRAS and TGF-b1 Signaling Pathway Debabrata (Dev) Mukhopadhyay 12.30 pm-1.30 pm Poster Session (Hallway) [ Poster numbers 1-25 + 25 posters for Baxi and Kulkarni Awards] 1.30 pm-2.30 pm Lunch Invited Lecture (Hall-A; 2.30 pm – 5.10 pm) SESSION 3 Chair: Dr. Kunal Ray & Dr. Arindam Maitra (AGILENT sponsored session) 2.30 pm - 2.50 pm IL-01.
    [Show full text]
  • One Size Does Not Fit All—The Future of Cancer Therapy
    Journal of the Indian Institute of Science A Multidisciplinary Reviews Journal ISSN: 0970-4140 Coden-JIISAD © Indian Institute of Science One Size does not Fit All—The Future of Cancer Therapy Sujaya Srinivasan and Kumaravel Somasundaram* Abstract | Cancer is a complex disease where normal cells of the body are REVIEWS transformed such that they begin to divide in an uncontrolled manner and can even invade other tissues in the body. Cancer can occur in many differ- ent tissues in the body, each requiring different forms of treatment. It is a dis- ease that is caused by changes or mutations in genes, leading to a cascade of other genetic changes in the body. There is a high degree of genetic het- erogeneity in tumors of a single type of cancer, which might explain why each patient responds to standard treatments differently. This makes it necessary to tailor treatments for cancer patients based on the molecular profiles of their tumors. This is the idea behind personalized medicine, where patients are treated based on their individual genetic changes or molecular profiles. In this paper, we look at some of the molecular profiles that are commonly used Mutation: It is a permanent in different types of cancers, and some personalized therapies that already change in the DNA sequence of a gene resulting in a defec- exist. In addition, we also attempt to predict how cancer treatment will be tive gene and can alter the revolutionized by some of the new technologies that are emerging today. amino acid sequence of the protein encoded by the gene Keywords: Cancer, oncology, personalized medicine, targeted therapy, gene signatures, molecular resulting in the production of signatures, genomics, next generation sequencing a non functional protein.
    [Show full text]