Evidence-Based Practice in Primary Care Practice in Primary Second Edition Evidence-Based

Total Page:16

File Type:pdf, Size:1020Kb

Evidence-Based Practice in Primary Care Practice in Primary Second Edition Evidence-Based Second edition Evidence-based Practice in Primary Second edition Care In the Royal Society of Medicine Journal review of the first edition of this book, David Seamark wrote: “Evidence-based medicine provokes reactions from enthusiasm to loathing. Silagy and Haines’ well laid out book seeks to reconcile the two extremes by explaining why evidence-based medicine is relevant to daily practice in primary care and by asking primary care professionals to regard themselves as learners and not just practitioners.” Hence the text is split into two sections, the first dealing with the way primary care workers can begin to understand and practise in an evidence-based way, the second addressing the broader issue of engendering a more evidence-based culture in their practice. Contributions from leading practitioners around the world ensure that the discussions are relevant internationally. Evidence - based In this second edition each chapter has been thoroughly revised in the light of changes both in attitudes to and practice of evidence-based medicine. Emphasis is given to the need for continuing medical education using effective searching and critical appraisal, and to Practice in integrating research findings into practice. As with the first edition, this revised text will be an invaluable guide for anyone in primary Primary Care health care, providing authoritative and thoughtful information on this important development in clinical practice. www.bmjbooks.com Edited by Chris Silagy Silagy and Haines and Andrew Haines Evidence – based Medicine / Primary Care 1403 Evid Based Pract 20/6/1 3:16 pm Page i CHAPTER TITLE Evidence-based Practice in Primary Care Second edition i This Page Intentionally Left Blank 1403 Evid Based Pract 20/6/1 3:16 pm Page iii CHAPTER TITLE Evidence-based Practice in Primary Care Second edition Edited by Chris Silagy Professor and Director, Institute of Health Services Research, Monash University, Australia and Andrew Haines Professor of Public Health and Primary Care and Dean, London School of Hygiene and Tropical Medicine, London, UK iii 1403 Evid Based Pract 20/6/1 3:16 pm Page iv CRITICAL CARE FOCUS: ANTIBIOTIC RESISTANCE © BMJ Books 2001 BMJ Books is an imprint of the BMJ Publishing Group All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording and/or otherwise, without the prior written permission of the publishers. First published in 1998 Reprinted 1999 Second edition 2001 by BMJ Books, BMA House, Tavistock Square, London WC1H 9JR www.bmjbooks.com British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library ISBN 0 7279 1568 1 Typeset by FiSH Books Ltd. Printed and bound by Selwood Printing Ltd., West Sussex iv 1403 Evid Based Pract 20/6/1 3:16 pm Page v Contents Contributors vii Preface to the second edition ix 1 Evidence-based practice in primary care: an introduction 1 Chris Silagy and David Weller PART 1 – EVIDENCE-BASED HEALTH CARE AND THE INDIVIDUAL PATIENT 2 Getting started: how to set priorities and define questions 15 Paramjit Gill and Margaret Lloyd 3 Tracking down the evidence 23 Chris Del Mar 4 Critical appraisal 38 Tim Lancaster and Michael Weingarten 5 Applying the evidence with patients 49 Trisha Greenhalgh and Gavin Young 6 Screening and diagnostic tests 67 J André Knottnerus and Ron A G Winkens 7 How to assess the effectiveness of applying the evidence 83 Richard Baker and Richard Grol PART 2 – STRATEGIES TO DEVELOP A CULTURE OF EVIDENCE-BASED HEALTH CARE IN PRIMARY CARE 8 An overview of strategies to promote implementation of evidence-based health care 101 Andrew D Oxman and Signe Flottorp v 1403 Evid Based Pract 20/6/1 3:16 pm Page vi 9 Identifying and using evidence-based guidelines in general practice 120 Jeremy Grimshaw and Martin Eccles 10 Role of information technology 135 Michael Kidd and Ian Purves 11 Continuing medical education as a means of lifelong learning 142 Dave Davis and Mary Ann O’Brien 12 Integrating research evidence into practice 157 Andrew Haines and Stephen Rogers Appendix 1 Using MEDLINE to search for evidence (Ovid software): some background information and sample searches 175 Barbara Cumbers and Reinhard Wentz Appendix 2 Some further sources of information and resources that facilitate evidence-based practice 190 Index 197 vi 1403 Evid Based Pract 20/6/1 3:16 pm Page vii Contributors Baker R, Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, UK Cumbers B, Library, Central Middlesex Hospital NHS Trust, London, UK Davis D, Office of Continuing Education, Faculty of Medicine, University of Toronto, Canada Del Mar C, Centre for General Practice, University of Queensland Medical School, Australia Eccles M, Centre for Health Services Research, University of Newcastle upon Tyne, UK Flottorp S, Health Services Research Unit, National Institute of Public Health, Oslo, Norway Gill P, Department of Primary Care and General Practice, University of Birmingham, UK Greenhalgh T, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK Grimshaw J, Health Services Research Unit, University of Aberdeen, UK Grol R, Centre for Quality of Care Research, Universities of Nijmegen and Maastricht, The Netherlands Haines A, London School of Hygiene and Tropical Medicine, London, UK Kidd M, Department of General Practice, The University of Sydney, Australia Knottnerus JA, Netherlands School of Primary Care Research, University of Maastricht, The Netherlands Lancaster T, Department of Primary Health Care, Oxford University, Oxford, UK vii 1403 Evid Based Pract 20/6/1 3:16 pm Page viii EVIDENCE-BASED PRACTICE IN PRIMARY CARE Lloyd M, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK O’Brien MA, Chedoke–McMaster Hospitals, Hamilton, Canada Oxman A, Health Services Research Unit, National Institute of Public Health, Oslo, Norway Purves I, Sowerby Centre for Health Informatics, University of Newcastle upon Tyne, UK Rogers S, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK Silagy CA, Institute of Health Services Research, Monash University, Australia Weingarten M, Department of Family Medicine, Sackler School of Medicine, Tel Aviv University, Israel Weller D, Department of General Practice, University of Edinburgh, Edinburgh, UK Wentz R, Imperial College Library, Chelsea and Westminster Hospital, London, UK Winkens RAG, Transmural and Diagnostic Centre, Maastricht, The Netherlands Young G, The Surgery, Barn Croft, Temple Sowerby, Penrith, Cumbria, UK viii 1403 Evid Based Pract 20/6/1 3:16 pm Page ix Preface to the second edition During the last decade, the concepts of evidence-based practice have stimulated wide-ranging interest amongst health professionals as one of the central foundations underpinning the organisation and provision of health care services. Some people have suggested evidence-based practice represents a new paradigm whilst others argue it is nothing more than a repackaging of old concepts wrapped in new jargon. Irrespective of these divergent views, there is little doubt that the ideas embraced by evidence- based practice are beginning to impact on most health care disciplines, including general practice. Although there are other books on various aspects of evidence-based practice, many of these have focused on the acquisition of specific skills, such as critical appraisal, or on the wide implications for the health system of systematically using research evidence to influence health policy and practice. However, there has been a paucity of information targeting the relevance of evidence-based approaches specifically to general practice. General practice is, by its very nature, a highly complex discipline that has been characterised by a high proportion of less well-differentiated problems that frequently highlight the interplay between biological, psychological and social factors. Through trying to confront and unravel these factors, we became increasingly aware of the need for a book which specifically addressed the relevance and place of evidence-based practice for primary care practitioners. We have elected to use the term “general practitioner” although we are, of course, aware of the different terminology employed to describe primary care doctors around the world. In addition, we recognise the importance of a multidisciplinary approach to involving the primary care team in activities to promote effective practice. This book is not intended to be a step by step “how to do it” guide. For general practitioners who are interested in developing a detailed knowledge and skills in this area, a list of further reading and other resources is provided. There are also a growing number of short courses on evidence- based practice which are being offered by academic institutions and professional societies throughout the world. Instead, it informs those general practitioners and primary care teams who wish to gain an overview of the topic. ix 1403 Evid Based Pract 20/6/1 3:16 pm Page x EVIDENCE-BASED PRACTICE IN PRIMARY CARE The book is organised into two separate parts. The first deals with the approach to utilising an evidence-based approach to the care of individual patients. It begins with how to ask and refine a good clinical question, then track down the necessary evidence and critically appraise it. Subsequent chapters deal with how to apply the evidence, the latter of the two having a specific focus on the application of evidence relating to screening and diagnostic tests. The final chapter in Part 1 deals with how to evaluate the impact of applying the evidence. In the second part of the book, the focus is on the strategies required at professional and disciplinary level in order to develop an ongoing culture of evidence-based practice within primary care.
Recommended publications
  • North-East COVID-19 Observatory: Issue 11
    KYDD, A., MACLEAN, C. and OZA, R. (eds.) 2020. North-east COVID-19 observatory: issue 11. Aberdeen: Robert Gordon University. North-east COVID-19 observatory: issue 11. KYDD, A., MACLEAN, C. and OZA, R. 2020 This newsletter was originally published via e-mail and has been converted with minor formatting changes to PDF during deposit on OpenAIR. This document was downloaded from https://openair.rgu.ac.uk North-East COVID-19 Observatory Issue 11—26th October 2020 Welcome Welcome to our eleventh issue of the Observatory. This will now be issued monthly, with each month hav- ing a dedicated theme. We include news, professional matters, and relevant professional and light reading. Each issue has one or two guest contributors with a specialist interest in the chosen theme. This month we have a very new theme - Long Covid - and, because of this, we are delighted to have Colin MacLean, Liaison Librarian Research Support at Robert Gordon University as our guest writer. Colin is also a member of the editorial team of the Observatory - so we are grateful for his extra input into this new and evolving phenom- ena. As ever, we value any feedback and encourage people to request themes or to send in resources that others might find interesting. Theme: Long Covid For many people, the experience of Covid-19 will go beyond being a respiratory illness that they will recover from in two or three weeks but instead manifest as several confounding syn- dromes with long term impacts on health. Post-viral fatigue is often experienced as a conse- quence of viral disease but that, added to the aftermath of intensive care treatment, creates a physically and mentally challenging set of potentially long term conditions.
    [Show full text]
  • Diffusion of Innovations in Service Organizations: Systematic Review and Recommendations
    Diffusion of Innovations in Service Organizations: Systematic Review and Recommendations TRISHA GREENHALGH, GLENN ROBERT, FRASER MACFARLANE∗,PAULBATE, and OLIVIA KYRIAKIDOU∗ University College London; ∗University of Surrey This article summarizes an extensive literature review addressing the question, How can we spread and sustain innovations in health service delivery and or- ganization? It considers both content (defining and measuring the diffusion of innovation in organizations) and process (reviewing the literature in a sys- tematic and reproducible way). This article discusses (1) a parsimonious and evidence-based model for considering the diffusion of innovations in health service organizations, (2) clear knowledge gaps where further research should be focused, and (3) a robust and transferable methodology for systematically re- viewing health service policy and management. Both the model and the method should be tested more widely in a range of contexts. Key Words: Diffusion of innovation, systematic review, implementation. his article summarizes the findings of a systematic literature review of the diffusion of service inno- T vations. The United Kingdom Department of Health explic- itly commissioned this work, which was carried out between October 2002 and December 2003, for its National Health Service’s exten- sive modernization agenda (UK Department of Health 2001). Our review, which supplements and extends previous overviews and meta- analyses (Damanpour 1991, 1992, 1996; Granados et al. 1997; Meyers, Sivakumar, and Nakata 1999; Rogers 1995; Tornatsky and Klein 1982; Address correspondence to: Trisha Greenhalgh, University College London, Room 403, Holborn Union Building, Highgate Hill, London N19 5LW, United Kingdom (e-mail: [email protected]). The Milbank Quarterly, Vol.
    [Show full text]
  • COVID-19 Surveillance in a Primary Care Sentinel Network: In-Pandemic Development of an Application Ontology
    JMIR PUBLIC HEALTH AND SURVEILLANCE de Lusignan et al Original Paper COVID-19 Surveillance in a Primary Care Sentinel Network: In-Pandemic Development of an Application Ontology Simon de Lusignan1, MD; Harshana Liyanage1, PhD; Dylan McGagh1, BSc; Bhautesh Dinesh Jani2, MBChB; Jorgen Bauwens3, MSc, MPH; Rachel Byford1, BSc; Dai Evans4, BSc, MBBS; Tom Fahey5, MSc, MD; Trisha Greenhalgh1, FMedSci; Nicholas Jones1, MBBS, MSc; Frances S Mair2, MBMChB, MD; Cecilia Okusi1, MRES; Vaishnavi Parimalanathan1, MPH; Jill P Pell2, MSc, MD; Julian Sherlock1, BSc; Oscar Tamburis6, MEng, PhD; Manasa Tripathy1, BSc, MSc; Filipa Ferreira1, BEng, MSc, PhD; John Williams1, MSc, FRCGP, FFCI; F D Richard Hobbs1, FMedSci, FRCGP, MA, FRCP 1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom 2General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom 3University Children©s Hospital Basel, University of Basel, Basel, Switzerland 4PRIMIS, University of Nottingham, Nottingham, United Kingdom 5Department of General Practice, Royal College of Surgeons, Ireland, Dublin, Ireland 6Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy Corresponding Author: Simon de Lusignan, MD Nuffield Department of Primary Care Health Sciences University of Oxford Radcliffe Primary Care Building Radcliffe Observatory Quarter, Woodstock Rd Oxford, OX2 6GG United Kingdom Phone: 44 1865617283 Email: [email protected] Abstract Background: Creating an ontology for COVID-19 surveillance should help ensure transparency and consistency. Ontologies formalize conceptualizations at either the domain or application level. Application ontologies cross domains and are specified through testable use cases. Our use case was an extension of the role of the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) to monitor the current pandemic and become an in-pandemic research platform.
    [Show full text]
  • A Narrative Analysis of UK Media Depictions of Remote GP Consulting
    Original research Med Humanities: first published as 10.1136/medhum-2020-012111 on 29 March 2021. Downloaded from ‘From disaster, miracles are wrought’: a narrative analysis of UK media depictions of remote GP consulting in the COVID-19 pandemic using Burke’s pentad Gilly Mroz,1 Chrysanthi Papoutsi,2 Trisha Greenhalgh 2 1Zoology, University of Oxford, ABSTRACT Crises, these authors suggest, are characterised by Oxford, UK During crises (major events characterised by uncertainty, three things: uncertainty, urgency and threat. A key 2Primary Care Health Sciences, University of Oxford, Oxford, UK urgency and threat), society must make sense of element of leadership in times of crisis is sensem- rapidly unfolding events. This happens mainly through aking—producing an account of what is happening, Correspondence to narrativising—depicting a setting, characters and a as it is happening, along with a real-time interpre- Professor Trisha Greenhalgh, meaningful sequence of events and actions unfolding tation of its significance (Boin, Stern, and Sundelius Primary Care Health Sciences, over time. In the early months of the pandemic, UK 2016). University of Oxford Nuffield general practice shifted from face- to- face consultations Department of Primary Care Coronavirus (COVID-19) was undoubtedly a Health Sciences, Oxford, to a remote-by- default model (telephone, video or e- crisis. By the time WHO declared a pandemic on Oxfordshire, UK; consultation). This shift was initially widely accepted by 11 March 2020, it was already clear that the virus trish. greenhalgh@ phc. ox. ac. uk press and public, but support waned after a politician was highly contagious, potentially deadly and declared that the change would be permanent.
    [Show full text]
  • The Politics of Evidence: from Evidence- Based Policy to the Good Governance of Evidence
    Justin Parkhurst The politics of evidence: from evidence- based policy to the good governance of evidence Book (Published version) Original citation: Parkhurst, Justin (2017) The politics of evidence: from evidence-based policy to the good governance of evidence. Routledge Studies in Governance and Public Policy. Routledge, Abingdon, Oxon, UK. ISBN 9781138939400 Reuse of this item is permitted through licensing under the Creative Commons: © 2017 The Author CC BY-NC-ND This version available at: http://eprints.lse.ac.uk/68604/ Available in LSE Research Online: December 2016 LSE has developed LSE Research Online so that users may access research output of the School. Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. You may freely distribute the URL (http://eprints.lse.ac.uk) of the LSE Research Online website. ‘This book is a marvellous interdisciplinary synthesis, grounded in case examples and at once critical and constructive. As such, it is both instructive for policy practitioners as well as moving the scholarship of the field forward.’ –Vivian Lin, Professor of Public Health, La Trobe University, Australia ‘This is essential reading for anybody working on the smarter use of evidence by government. It catalogues the many biases twisting how research is used by policymakers. It also addresses a vital challenge in our sector – a lack of legitimacy. As well as the academic rigour of this book, there are practical tips on what we can do about these problems, and lessons from across the globe showing where we get it wrong – and how we might get it right.’ – Jonathan Breckon, Head of the Alliance for Useful Evidence, UK ‘This important book goes well beyond standard analyses of evidence informed policy with detailed discussions of the politics of evidence and the political origins (and the cognitive psychology) of bias in the use of research evidence.
    [Show full text]
  • No Deal’ Brexit and Health
    1st Floor, Bride House, 18-20 Bride Lane, London, EC4Y 8EE Rt Hon Theresa May MP The Prime Minister 10 Downing Street London SW1A 2AA 22 February 2019 Dear Prime Minister ‘NO DEAL’ BREXIT AND HEALTH We write as leaders, professionals and actively engaged individuals from across the health and social care sector, bringing the perspectives of patients, service users, unpaid carers, clinicians, charities and other experts. We are urging you to prevent the UK from leaving the European Union without a negotiated deal. Based on what we are learning from the front line, we are increasingly alarmed at the risks associated with a ‘no deal’ Brexit. As the Government’s contingency planning demonstrates, a ‘no deal’ Brexit poses grave risks to public health and patient safety, and would require extraordinary measures in mitigation. The immediate issue is the supply of medicines, medical devices and other essential products. But a ‘no deal’ exit would also have serious implications for the availability of staff in care and research settings, the arrangements governing reciprocal healthcare, the regulation of medicines and devices, and the UK’s involvement in pan-European research and innovation and in public health and prevention initiatives. All of these would be affected over an indefinite period of time. The most disadvantaged in society would be likely to be most at risk. It is becoming ever clearer to us that the Government’s contingency plans are unlikely to cover all eventualities and work for all patients, carers and citizens. We believe it is the responsibility of the Government, in cooperation as necessary with Parliamentarians and the European Union, to rule out the possibility of a ‘no deal’ Brexit.
    [Show full text]
  • BMJ Open, Vol
    Research Archive Citation for published version: Trisha Greenhalgh, et al, ‘SCALS: a fourth-generation study of assisted living technologies in their organisational, social, political and policy context’, BMJ Open, Vol. 6 (2): e010208, February 2016. DOI: http://dx.doi.org/10.1136/bmjopen-2015-010208 Document Version: This is the Published version. Copyright and Reuse: Published by the BMJ Publishing Group Limited. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ Enquiries If you believe this document infringes copyright, please contact the Research & Scholarly Communications Team at [email protected] Downloaded from http://bmjopen.bmj.com/ on February 5, 2018 - Published by group.bmj.com Open Access Protocol SCALS: a fourth-generation study of assisted living technologies in their organisational, social, political and policy context Trisha Greenhalgh,1 Sara Shaw,1 Joe Wherton,2 Gemma Hughes,1 Jenni Lynch,3 Christine A’Court,1 Sue Hinder,2 Nick Fahy,1 Emma Byrne,2 Alexander Finlayson,1 Tom Sorell,3 Rob Procter,4 Rob Stones5 To cite: Greenhalgh T, ABSTRACT et al Strengths and limitations of this study Shaw S, Wherton J, . Introduction: Research to date into assisted living SCALS: a fourth-generation technologies broadly consists of 3 generations: ▪ ‘ ’ study of assisted living Introduces and applies the fourth generation technical design, experimental trials and qualitative technologies in their approach to the study of assisted living technolo- organisational, social, studies of the patient experience.
    [Show full text]
  • Developing Services for Long Covid: Lessons from a Study of Wounded Healers
    medRxiv preprint doi: https://doi.org/10.1101/2020.11.13.20231555; this version posted November 16, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Developing services for long Covid: lessons from a study of wounded healers Dr Emma Ladds,1 academic clinical fellow Dr Alex Rushforth,1 postdoctoral researcher Dr Sietse Wieringa,1 postdoctoral clinical researcher Dr Sharon Taylor,2,3 child psychiatrist, honorary senior lecturer and expert by experience Dr Clare Rayner,4 GP and expert by experience Miss Laiba Husain,1 research assistant Professor Trisha Greenhalgh,1 clinical professor 1 Nuffield Department of Primary Care Health Sciences, University of Oxford 2 Central and North West London NHS Foundation Trust and 3 Division of Psychiatry Imperial College London, United Kingdom 4 Independent Occupational Physician, Manchester Corresponding author: E. Ladds [email protected] Nuffield Department of Primary Care Health Sciences University of Oxford, Oxford OX2 6GG UK Key words: Post-acute Covid-19, Chronic Covid-19, long Covid, qualitative study, new service model, quality standards NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. medRxiv preprint doi: https://doi.org/10.1101/2020.11.13.20231555; this version posted November 16, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
    [Show full text]
  • How to Read a Paper: the Basics of Evidence-Based Medicine,Fifthedition.Trishagreenhalgh
    How to Read a Paper The Basics of Evidence-Based Medicine FIFTH EDITION How to Read aPaper The Basics of Evidence-Based Medicine FIFTH EDITION Trisha Greenhalgh Professor of Primary Health Care Barts and the London School of Medicine and Dentistry Blizard Institute London, UK This edition first published 2014, © 2010, 2014 by John Wiley & Sons Ltd BMJ Books is an imprint of BMJ Publishing Group Limited, used under licence by John Wiley & Sons. Registered office: JohnWiley&Sons,Ltd,TheAtrium,SouthernGate,Chichester,WestSussex, PO19 8SQ, UK Editorial offices: 9600 Garsington Road, Oxford, OX4 2DQ, UK The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK 111 River Street, Hoboken, NJ 07030-5774, USA For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com/wiley-blackwell The right of the author to be identified as the author of this work has been asserted in accordance with the UK Copyright, Designs and Patents Act 1988. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher. Designations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners.
    [Show full text]
  • Persistent Symptoms After Covid-19: Qualitative Study of 114 “Long Covid” Patients and Draft Quality Criteria for Services
    medRxiv preprint doi: https://doi.org/10.1101/2020.10.13.20211854; this version posted October 14, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Original article submitted to Medrxiv preprint service October 2020 Persistent symptoms after Covid-19: qualitative study of 114 “long Covid” patients and draft quality criteria for services Emma Ladds,1 academic clinical fellow Alex Rushforth,1 postdoctoral researcher Sietse Wieringa,1 postdoctoral clinical researcher Sharon Taylor,2,3 child psychiatrist, honorary senior lecturer and expert by experience Clare Rayner,4 occupational physician and expert by experience Laiba Husain,1 research assistant Trisha Greenhalgh,1 clinical professor 1 Nuffield Department of Primary Care Health Sciences, University of Oxford 2 3 Central and North West London NHS Foundation Trust and Imperial College School of Medicine, London, United Kingdom 4 Independent Occupational Physician, Manchester Corresponding author: T Greenhalgh [email protected] Nuffield Department of Primary Care Health Sciences University of Oxford, Oxford OX2 6GG UK Key words: Post-acute Covid-19, Chronic Covid-19, long Covid, qualitative study, quality standards 5979 words NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice.1 medRxiv preprint doi: https://doi.org/10.1101/2020.10.13.20211854; this version posted October 14, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
    [Show full text]
  • Press Release
    Press release Embargoed until 10.00 (GMT) Friday 9 May 2014 44 leading medical experts recognised for excellence in research 44 researchers from across the UK have been recognised for their contribution to the advancement of medical science by election to the Fellowship of the Academy of Medical Sciences. Academy Fellows are elected for excellence in medical research, for innovative application of scientific knowledge or for their conspicuous service to healthcare. The expertise of the new Fellows includes haematology, bioinformatics, immunology, psychiatry, biochemistry and health services provision. This year, fifteen (34%) of the new Fellows are women, compared to 23.2% of bioscience professors in the UK.* Professor Sir John Tooke PMedSci, President of the Academy of Medical Sciences said, “The Academy of Medical Sciences represents the excellence and diversity of medical science in the UK, and this is evident in the broad range of expertise demonstrated by this year’s new Fellows. They each bring a unique perspective which we will value immensely – from the industry experience of Fellows such as Professor Jackie Hunter to the policy knowledge of Baroness Finlay. Their election is a much deserved honour for the outstanding achievements they have shown throughout their careers. I know they will contribute greatly to the Academy, and I am delighted to welcome them all to the Fellowship.” Baroness Ilora Finlay of Landaff FMedSci is Professor of Palliative Medicine at Cardiff University, and a consultant at the Velindre Cancer Centre. In 2003, driven by her work with terminally ill lung cancer patients, she proposed a parliamentary bill to ban smoking in public buildings, and has worked with the government closely to advise on UK policies regarding organ donation, carbon monoxide poisoning, sunbed usage, bereavement in children and the care of prisoners.
    [Show full text]
  • Long COVID Gains Acceptance As Many Questions Remain Unanswered
    Long COVID Gains Acceptance as Many Questions Remain Unanswered By Susan Carr, Senior writer …covid-19 has brought the complexity of science and policy making in the context of uncertainty into sharp focus.1(1) — Harry Rutter, Miranda Wolpert, Trisha Greenhalgh The past year has been an exercise in humility. For all that was quickly learned about the new SARS-CoV- 2 virus and COVID-19, there have been constant reminders of what is not yet known, including the infection’s long-term implications. In March and April 2020, most COVID-19 patients who managed their symptoms at home and recovered considered themselves fortunate and looked forward to returning to normal in a few weeks, as if they had had the flu or a bad cold. But as April became May, June and beyond, some patients were not able to shake symptoms that came and went like an unpredictable tide. Many drew on past experience and assumed they could tough out the tail end of the illness. Some found that friends, family members and even doctors they consulted for advice attributed their ongoing symptoms to stress, nerves, lack of resolve or a different, underlying condition. It was only when these patients turned to social media for peer support, discovered a growing community of “long haulers,” and started collecting data that the media and medical establishment began to pay attention and realize that for some, COVID is a long- term, perhaps chronic, debilitating illness.2-5 Because terminology and definitions are still being developed and data is scarce, the percentage of patients with persistent or chronic symptoms is not yet known.
    [Show full text]