JMIR PUBLIC HEALTH AND SURVEILLANCE de Lusignan et al Original Paper COVID-19 Surveillance in a Primary Care Sentinel Network: In-Pandemic Development of an Application Ontology Simon de Lusignan1, MD; Harshana Liyanage1, PhD; Dylan McGagh1, BSc; Bhautesh Dinesh Jani2, MBChB; Jorgen Bauwens3, MSc, MPH; Rachel Byford1, BSc; Dai Evans4, BSc, MBBS; Tom Fahey5, MSc, MD; Trisha Greenhalgh1, FMedSci; Nicholas Jones1, MBBS, MSc; Frances S Mair2, MBMChB, MD; Cecilia Okusi1, MRES; Vaishnavi Parimalanathan1, MPH; Jill P Pell2, MSc, MD; Julian Sherlock1, BSc; Oscar Tamburis6, MEng, PhD; Manasa Tripathy1, BSc, MSc; Filipa Ferreira1, BEng, MSc, PhD; John Williams1, MSc, FRCGP, FFCI; F D Richard Hobbs1, FMedSci, FRCGP, MA, FRCP 1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom 2General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom 3University Children©s Hospital Basel, University of Basel, Basel, Switzerland 4PRIMIS, University of Nottingham, Nottingham, United Kingdom 5Department of General Practice, Royal College of Surgeons, Ireland, Dublin, Ireland 6Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy Corresponding Author: Simon de Lusignan, MD Nuffield Department of Primary Care Health Sciences University of Oxford Radcliffe Primary Care Building Radcliffe Observatory Quarter, Woodstock Rd Oxford, OX2 6GG United Kingdom Phone: 44 1865617283 Email:
[email protected] Abstract Background: Creating an ontology for COVID-19 surveillance should help ensure transparency and consistency. Ontologies formalize conceptualizations at either the domain or application level. Application ontologies cross domains and are specified through testable use cases. Our use case was an extension of the role of the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) to monitor the current pandemic and become an in-pandemic research platform.