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SRBR 2006 Program Book Tenth Meeting Society for Research on Biological Rhythms Program and Abstracts SRBR May 21–25, 2006 Sandestin Golf and Beach Resort Sandestin, FL SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS i Executive Committee Advisory Board G.T.J. van der Horst Erasmus University William J. Schwartz, President Timothy J. Bartness University of Massachusetts Medical Georgia State University Russell N. Van Gelder School Washington University Vincent M. Cassone Martha Gillette, President-Elect Texas A & M Univeristy David R. Weaver University of Illinois University of Massachusetts Medical Philippe Delagrange Center Paul Hardin, Secretary Institut de Recherches Servier Texas A&M University Program Committee France Marie Dumont University of Montreal Vincent Cassone, Treasurer Carla Green, Program Chair Texas A&M University Russell Foster University of Virginia Imperial College of Science Josephine Arendt, Member-at-Large Greg Cahill University of Surrey Jadwiga M. Giebultowicz University of Houston Oregon State University Benjamin Rusak, Member-at-Large Michael Hastings Dalhousie University Martha Gillette MRC University of Illinois Ueli Schibler, Member-at-Large Takao Kondo University of Geneva Carla Green Nagoya University University of Virginia Journal of Biological Theresa Lee Rhythms Erik Herzog University of Michigan Washington University Johanna Meijer Editor-in-Chief Helena Illnerova Leiden University Czech Academy of Sciences Martin Zatz Ignacio Provencio National Institute of Mental Health Carl Johnson University of Virginia Vanderbilt University Associate Editors Louis Ptacek Elizabeth Klerman University of California, San Francisco Josephine Arendt Brigham & Women’s Hospital University of Surrey Paul Taghert Charalambos P. Kyriacou Washington University Paul Hardin University of Leicester Texas A&M University Joseph Takahashi Jennifer Loros Northwestern University Michael Hastings Dartmouth Medical Center MRC, Cambridge Travel Award Committee Ralph E. Mistleberger Sato Honma Simon Fraser University Ken Wright Hokkaido University School of University of Colorado Medicine Larry Morin SUNY, Stony Brook Deborah Bell-Pedersen William J, Schwartz Texas A&M University of Massachusetts Medical Ferenc Nagy School Hungarian Academy of Sciences Horacio de la Iglesia University of Washington Hitoshi Okamura Editorial Board Kobe University School of Medicine David Welsh Serge Daan The Scripps Institute Till Roenneberg University of Groningen Ludwig Maximilian Universitat Projectionists Bruce Goldman Rae Silver University of Connecticut Didem Goz Columbia University Ozgur Tataroglu Terry Page Laura Smale Karla Marz Vanderbilt University Michigan State University Misty Hurt Ueli Schibler Shihoko Kojima Martin Straume University of Geneva Ashli Moore University of Virginia Nina Vujovic Michael Terman Columbia University iI TENTH MEETING PROGRAM AND ABSTRACTS Tenth Meeting Society for Research on Biological Rhythms Program and Abstracts SRBR May 21–25, 2006 Sandestin Golf and Beach Resort Sandestin, FL The SRBR wishes to thank the following for their contributions: Actigraph Alliance Pharmaceuticals Alpco Diagnostics NINDS (National Institute of Neurological Disease and Stroke) Pzier Takeda Pharmaceuticals Sage Publications SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS iII iV TENTH MEETING PROGRAM AND ABSTRACTS Table of Contents General Information . 2 President’s Welcome Registration SRBR Information and Message Desk Conference Center Information Instructions to Presenters Social Events Meeting at a Glance . 4 Program for 2006 SRBR Meeting . 6 Poster Session 72–282 . 18 Abstracts . 30 Index of Authors . 180 Maps . 188 SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 1 General Information Registration Meeting registration will take place on Sunday, President’s Welcome May 21, from 15:00 until 19:00 and on May Twenty years ago, on November 12, 1986, Fred 22–25 from 8:00 until 11:00 and 14:30 until Turek, Dave Hudson, Joe Takahashi, and Gene 16:30 May 22–24 in the Foyer of the Baytowne Block founded the Society for Research on Conference Centre. Biological Rhythms. Who would have imagined that today we are analyzing the structural biology Early Registration: of bacterial clock proteins? Or that we are Postmarked by April 5, 2006 performing real-time measurements of rhythmic SRBR Member: $325.00 gene expression within individual cells in a dish? Or that we are delineating the neurobiology of Non-Member: $375.00 a neurotransmitter that underlies narcolepsy? SRBR Student Member: $165.00 And that’s just for starters. Every other year, we have been gathering at this meeting to Non-Member Student: $190.00 announce, debate, and celebrate these advances, Guest Registration: $75.00 in presentations that cut across disciplines, Late Registration: approaches, and organisms. Postmarked after April 5, 2006 Welcome to the 10th Biennial Meeting of the Society for Research on Biological Rhythms. I SRBR Member: $350.00 wish to gratefully thank Carla Green and her Non-Member: $400.00 Program Committee for expertly organizing the scientific treat you are about to enjoy, Ken Wright, SRBR Student Member: $175.00 Jr. and his committee for awarding our trainee Non-Member Student: $200.00 travel fellowships, Wendy Pickering and Karen Guest Registration: $100.00 Nichols at Conferences and Institutes for their fantastic work to ensure that the meeting runs Membership rates apply to individuals who have smoothly, and our government and corporate joined SRBR before the meeting and have paid sponsors for making it all possible. current dues. Student rates apply to registrants who will not have received their Ph.D. or M.D. And, of course, I extend my special thanks to all degree at the time of the meeting. Registered of you, presenters and participants, for sharing participants and guests are invited to the your passion, energy, and intelligence to make the opening reception and the closing banquet. meeting such a biennial success. To everyone, my best wishes for a fruitful week of sun, sand, and circadian—and ultradian and infradian—biology. William J. Schwartz President, SRBR, 2004–2006 2 TENTH MEETING PROGRAM AND ABSTRACTS SRBR Information and Message Desk The Society will maintain an information desk in the Foyer of the Baytowne Conference Centre from 8:00 to 11:00 on May 22-25, and from 14:30 to 16:30 on May 22–24. Late arrivals can register during these times. A message board will be located next to the information desk. Meeting participants are asked to check the message board routinely for mail, notes, and telephone messages. Conference Center Information The Baytowne Conference Center is conveniently located within walking distance of all properties. All SRBR scientific sessions and social events will take place at the Center. Instructions to Presenters All posters will be displayed throughout the meeting, with even numbered posters presented on Monday, May 22 and odd numbered posters presented on Wednesday, May 24, 2006. Please hang posters on Monday morning (May 22) between 8:00 and 10:00. All posters must by removed by 10:00 on Thursday, May 25. Computer projectors will be set up in each meeting room. PowerPoint presenters should bring their data on a computer or shared computer. Social Events The SRBR Opening Reception will begin at 19:00 on Sunday, May 21 on the Grand Lawn. A banquet for conference attendees and guests will be held in the Magnolia Ballroom on Thursday, May 25 at 20:00. SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 3 Meeting at a Glance All events will take place in the Sandestin Conference Center unless otherwise noted -Sunday May 21- 19:00–22:00 Opening Reception—Grand Lawn Monday May 22- 08:00–10:00 Poster Session Setup—Magnolia ABC 08:30–10:30 Symposium 1: Molecular Regulation of Circadian Rhythms—Azalea I Symposium 2: Neuronal Pacemaker Organization and Disorganization—Azalea II 10:30–11:00 Coffee Break—Magnolia Foyer 11:00–12:30 Slide Sessions A–C A) Mammalian Clock Genes I—Azalea I B) Photoperiodic Timers and Development—Azalea II C) Clocks and Disease—Azalea III 12:30–16:30 Free Time 16:30–18:30 Symposium 3: Circadian Clock Mechanisms I—Azalea I Symposium 4: Circadian Clocks and Cognition—Azalea II Symposium 5: Extra-SCN Oscillators—Azalea III Workshop I: Assessment of Chronotype: Tools and Tricks—Camellia II 20:00–22:30 Poster Session I: Even numbered posters—Magnolia ABC Tuesday May 23- 8:30–10:30 Symposium 6: Sleep and Human Circadian Biology—Azalea I Symposium 7: Transcription/Translation Feedback Loops and Neuronal Electrochemical Signaling—Azalea II 10:30–11:00 Coffee Break—Magnolia Foyer 11:00–12:30 Slide Sessions D–F D) Drosophila Clock Genes—Azalea I E) SCN—Azalea II F) Peripheral, Oscillators/Endocrine—Azalea III 12:30–16:30 Free Time 16:30–18:00 Presidential Symposium: Simple Principles for Complex Systems—Azalea I 18:00 Free Night 4 TENTH MEETING PROGRAM AND ABSTRACTS Wednesday May 24- 8:30–10:30 Symposium 8: Organization of the Mammalian Circadian Timing System: Centrifugal or Centripetal?—Azalea I Symposium 9: ‘Green’ Clocks: Conservation and Diversity of Circadian Architectures 10:30–11:00 Coffee Break—Magnolia Foyer 11:00–12:30 Slide Sessions G–I G) Entrainment—Azalea I H) Clocks and Metabolism—Azalea II I) Sleep—Azalea III 12:30–16:30 Free Time 16:30–20:30 Symposium 10: Mathematical Modelling—Azalea I Symposium 11: Circadian Clock Mechanisms II—Azalea II Symposium 12: Shedding Light on Human Clock Function Disorders—Azalea III Workshop II: Comparative Anatomy of Circadian Pacemaker Networks in Arthropod Brains—Camellia II 20:00–22:30
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