Appendix 1: Literature Search Strategy
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APPENDIX 1: LITERATURE SEARCH STRATEGY $ Truncation symbol adj Adjacent (i.e., terms are near/next to one another, any order) adj# Adjacent within # of words ti Title ab Abstract kw Keyword sh Subject heading/descriptor exp Explode subject heading fs Floating subject heading pt Publication type tn Trade name rn Registry number (i.e., CAS) tw Text word hw Heading word DATABASES LIMITS KEYWORDS/DESCRIPTORS Ovid Human Systematic Reviews/Meta-Analyses - Medline Medline In-Process & Other Non-Indexed Citations - Medline In-Process & Other Non- 1. Octreotid$.ti,ab. Indexed Citations 2. Longastatin$.ti,ab. - EMBASE 3. DRG-0115.ti,ab. - BIOSIS Previews 4. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 5. Sandostatin$.ti,ab. 6. SMS-LAR.ti,ab. 7. Sandoz 201-995.ti,ab. 8. 83150-76-9.rn. 9. or/1-8 10. ((meta adj analy$) or metaanaly$ or (met adj analy$) or metanaly$ or (health adj technology adj assessment$) or hta$1).ti,ab. 11. (technology adj assessment$ adj2 biomedical).ti,ab. 12. (technology adj assessment$ adj2 bio-medical).ti,ab. 13. ((systematic$ adj ((literature adj review$) or review$ or overview$)) or (methodologic$ adj ((literature adj review$) or review$ or overview$))).ti,ab. 14. ((quantitative adj (review$ or overview$ or synthes$)) or (research adj (integration$ or overview$))).ti,ab. 15. ((integrative adj2 (review$ or overview$)) or (collaborative adj (review$ or overview$)) or (pool$ adj analy$)).ti,ab. 16. or/10-15 17. 9 and 16 Medline 1. Octreotid$.ti,ab. 2. Longastatin$.ti,ab. 3. DRG-0115.ti,ab. 4. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 5. Sandostatin$.ti,ab. 6. SMS-LAR.ti,ab. 7. Sandoz 201-995.ti,ab. A-1 DATABASES LIMITS KEYWORDS/DESCRIPTORS 8. 83150-76-9.rn. 9. or/1-8 10. ((meta adj analy$) or metaanaly$ or (met adj analy$) or metanaly$ or (health adj technology adj assessment$) or hta$1).ti,ab. 11. (technology adj assessment$ adj2 biomedical).ti,ab. 12. (technology adj assessment$ adj2 bio-medical).ti,ab. 13. ((systematic$ adj ((literature adj review$) or review$ or overview$)) or (methodologic$ adj ((literature adj review$) or review$ or overview$))).ti,ab. 14. ((quantitative adj (review$ or overview$ or synthes$)) or (research adj (integration$ or overview$))).ti,ab. 15. ((integrative adj2 (review$ or overview$)) or (collaborative adj (review$ or overview$)) or (pool$ adj analy$)).ti,ab. 16. Meta-Analysis.pt. 17. Meta-Analysis.sh. 18. exp Technology Assessment, Biomedical/ 19. or/10-18 20. 9 and 19 EMBASE 1. *Octreotide/ 2. Octreotid$.ti,ab. 3. Longastatin$.ti,ab. 4. DRG-0115.ti,ab. 5. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 6. Sandostatin$.ti,ab. 7. SMS-LAR.ti,ab. 8. Sandoz 201-995.ti,ab. 9. Sandostatin.tn. 10. Sandostatin LAR.tn. 11. Omega.tn. 12. Octreotide.tn. 13. Longastatin.tn. 14. or/1-13 15. Meta-Analysis.sh. 16. Systematic review.sh. 17. Biomedical Technology Assessment.sh. 18. ((meta adj analy$) or metaanaly$ or (met adj analy$) or metanaly$ or (health adj technology adj assessment$) or hta$1).ti,ab. 19. (technology adj assessment$ adj2 biomedical).ti,ab. 20. (technology adj assessment$ adj2 bio-medical).ti,ab. 21. ((systematic$ adj ((literature adj review$) or review$ or overview$)) or (methodologic$ adj ((literature adj review$) or review$ or overview$))).ti,ab. 22. ((quantitative adj (review$ or overview$ or synthes$)) or (research adj (integration$ or overview$))).ti,ab. 23. ((integrative adj2 (review$ or overview$)) or (collaborative adj (review$ or overview$)) or (pool$ adj analy$)).ti,ab. 24. or/15-23 25. 14 and 24 BIOSIS 1. Octreotid$.hw,ti,ab. A-2 DATABASES LIMITS KEYWORDS/DESCRIPTORS 2. Longastatin$.hw,ti,ab. 3. DRG-0115.hw,ti,ab. 4. (SMS-201-995 or SM-201-995 or SAN-201-995).hw,ti,ab. 5. Sandostatin$.hw,ti,ab. 6. SMS-LAR.hw,ti,ab. 7. Sandoz 201-995.hw,ti,ab. 8. 83150-76-9.rn. 9. or/1-8 10. ((meta adj analy$) or metaanaly$ or (met adj analy$) or metanaly$ or (health adj technology adj assessment$) or hta$1).ti,ab. 11. (technology adj assessment$ adj2 (biomedical or bio-medical)).ti,ab. 12. ((systematic$ adj ((literature adj review$) or review$ or overview$)) or (methodologic$ adj ((literature adj review$) or review$ or overview$))).ti,ab. 13. ((quantitative adj (review$ or overview$ or synthes$)) or (research adj (integration$ or overview$))).ti,ab. 14. ((integrative adj2 (review$ or overview$)) or (collaborative adj (review$ or overview$)) or (pool$ adj analy$)).ti,ab. 15. or/10-14 16. 9 and 15 Performed 16 May 2006 99 unique records after de-duping in Reference Manager Medline In-Process & Other Non-Indexed Citations - 1 Medline – 42 EMBASE - 44 BIOSIS – 12 Ovid Economic Studies - Medline Medline In-Process & Other Non-Indexed Citations - Medline In-Process & Other Non- 1. Octreotid$.ti,ab. Indexed Citations 2. Longastatin$.ti,ab. - EMBASE 3. DRG-0115.ti,ab. - BIOSIS Previews 4. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 5. Sandostatin$.ti,ab. 6. SMS-LAR.ti,ab. 7. Sandoz 201-995.ti,ab. 8. 83150-76-9.rn. 9. or/1-8 10. (cost or costs or costing or cost-effective$).ti,ab. 11. (sensitivity analysis or sensitivity analyses).ti,ab. 12. (economic$ or pharmacoeconomic$ or pharmaco-economic$).ti,ab. 13. budget$.ti,ab. 14. (QOL or QOLY or QOLYs or HRQOL or QALY or QALYs or QALE or QALEs).ti,ab. 15. (Quality adj1 (life or (willingness adj2 pay))).ti,ab. 16. (Quality adj1 adjusted life year$).ti,ab. 17. (Quality adj1 adjusted life expectanc$).ti,ab. 18. or/10-17 19. 9 and 18 A-3 DATABASES LIMITS KEYWORDS/DESCRIPTORS Medline 1. Octreotide.sh. 2. Octreotid$.ti,ab. 3. Longastatin$.ti,ab. 4. DRG-0115.ti,ab. 5. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 6. Sandostatin$.ti,ab. 7. SMS-LAR.ti,ab. 8. Sandoz 201-995.ti,ab. 9. 83150-76-9.rn. 10. or/1-9 11. Economics.sh. 12. Economics, medical.sh. 13. Economics, pharmaceutical.sh. 14. exp "Costs and Cost Analysis"/ 15. exp health care costs/ 16. exp decision support techniques/ 17. economics.fs. 18. (cost or costs or costing or cost-effective$).ti,ab. 19. (sensitivity analysis or sensitivity analyses).ti,ab. 20. (economic$ or pharmacoeconomic$ or pharmaco-economic$).ti,ab. 21. budget$.ti,ab. 22. value of life.sh. 23. quality of life.sh. 24. quality-adjusted life years.sh. 25. (QOL or QOLY or QOLYs or HRQOL or QALY or QALYs or QALE or QALEs).ti,ab. 26. (Quality adj1 (life or (willingness adj2 pay))).ti,ab. 27. (Quality adj1 adjusted life year$).ti,ab. 28. (Quality adj1 adjusted life expectanc$).ti,ab. 29. or/11-28 30. 10 and 29 EMBASE 1. *Octreotide/ 2. Octreotid$.ti,ab. 3. Longastatin$.ti,ab. 4. DRG-0115.ti,ab. 5. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 6. Sandostatin$.ti,ab. 7. SMS-LAR.ti,ab. 8. Sandoz 201-995.ti,ab. 9. Sandostatin.tn. 10. Sandostatin LAR.tn. 11. Omega.tn. 12. Octreotide.tn. 13. Longastatin.tn. 14. or/1-13 15. exp health economics/ 16. exp economic evaluation/ 17. exp pharmacoeconomics/ 18. exp economic aspect/ 19. (cost or costs or costing or cost-effective$).ti,ab. A-4 DATABASES LIMITS KEYWORDS/DESCRIPTORS 20. (sensitivity analysis or sensitivity analyses).ti,ab. 21. (economic$ or pharmacoeconomic$ or pharmaco-economic$).ti,ab. 22. budget$.ti,ab. 23. quality adjusted life year.sh. 24. exp quality of life/ 25. (QOL or QOLY or QOLYs or HRQOL or QALY or QALYs or QALE or QALEs).ti,ab. 26. (Quality adj1 (life or (willingness adj2 pay))).ti,ab. 27. (Quality adj1 adjusted life year$).ti,ab. 28. (Quality adj1 adjusted life expectanc$).ti,ab. 29. pe.fs. 30. or/15-29 31. 14 and 30 BIOSIS 1. Octreotid$.hw,ti,ab. 2. Longastatin$.tw. 3. DRG-0115.tw. 4. (SMS-201-995 or SM-201-995 or SAN-201-995).tw. 5. Sandostatin$.tw. 6. SMS-LAR.tw. 7. Sandoz 201-995.tw. 8. 83150-76-9.rn. 9. or/1-8 10. Economic$.hw. 11. Pharmacoeconomic$.hw. 12. (cost or costs or costing or cost-effective$).ti,ab. 13. (sensitivity analysis or sensitivity analyses).ti,ab. 14. (economic$ or pharmacoeconomic$ or pharmaco-economic$).ti,ab. 15. budget$.ti,ab. 16. (QOL or QOLY or QOLYs or HRQOL or QALY or QALYs or QALE or QALEs).ti,ab. 17. (Quality adj1 (life or (willingness adj2 pay))).ti,ab. 18. (Quality adj1 adjusted life year$).ti,ab. 19. (Quality adj1 adjusted life expectanc$).ti,ab. 20. or/10-19 21. 9 and 20 Search Performed 30 May 2006 362 unique records after de-duping Reference Manager Medline In-Process & Other Non-Indexed Citations – 4 Medline – 141 EMBASE - 203 BIOSIS – 14 Ovid Human Clinical Trials: - Medline Medline In-Process & Other Non-Indexed Citations - Medline In-Process & Other Non- 1. Octreotid$.ti,ab. Indexed Citations 2. Longastatin$.ti,ab. A-5 DATABASES LIMITS KEYWORDS/DESCRIPTORS - EMBASE 3. DRG-0115.ti,ab. - BIOSIS Previews 4. (SMS-201-995 or SM-201-995 or SAN-201-995).ti,ab. 5. Sandostatin$.ti,ab. 6. SMS-LAR.ti,ab. 7. Sandoz 201-995.ti,ab. 8. 83150-76-9.rn. 9. or/1-8 10. (random$ or sham$ or placebo$ or (singl$ adj (blind$ or dumm$ or mask$)) or (doubl$ adj (blind$ or dumm$ or mask$))).ti,ab. 11. ((tripl$ adj (blind$ or dumm$ or mask$)) or (trebl$ adj (blind$ or dumm$ or mask$))).ti,ab.