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The Femoral Nerve Block Characteristics Using Ropivacaine 0.2% Alone, with Epinephrine, Or with Lidocaine and Epinephrine
SCIENTIFIC ARTICLES THE FEMORAL NERVE BLOCK CHARACTERISTICS USING ROPIVACAINE 0.2% ALONE, WITH EPINEPHRINE, OR WITH LIDOCAINE AND EPINEPHRINE A.M. TAHA1,2 AND A.M. ABD-ELmaKSOUD31* Keywords: anesthetic techniques, regional, femoral; anaesthetics local, ropivacaine; equipment, ultrasound machines. Abstract Background: The objective of this study was to evaluate the femoral nerve block characteristics (onset, success rate and duration) using ropivacaine 0.2% alone; with epinephrine, or with lidocaine and epinephrine compared with that using ropivacaine 0.5%. Methods: Ninety six patients were included in this prospective controlled double blind study and were randomly allocated into four equal groups (n=24). All the patients received ultrasound guided femoral nerve block using 15 ml of either ropivacaine 0.5% (group 1), ropivacaine 0.2% (group 2), ropivacaine 0.2% with epinephrine (group 3) and ropivacaine 0.2% with lidocaine and epinephrine (group 4). The block onset, success rate and duration were recorded. Results: The motor onset was significantly delayed in group 2 (compared with the other three groups) and in group 3 (compared with group 4). However, the block success rate and duration were comparable in the four groups. Conclusion: In femoral nerve block, ropivacaine 0.2% may have a comparable success rate and duration to ropivacaine 0.5% but with a remarkably delayed motor onset that may be improved by adding epinephrine. Addition of lidocaine may further accelerate the motor onset. Introduction The femoral nerve block (FNB) is a commonly indicated block, and ropivacaine is a widely used long acting local anesthetic (LA)1,2. Peripheral nerve blocks can provide excellent anesthesia and postoperative analgesia 3,4. -
Hormone Testing Summary
Accession # 00280399 Female Sample Report 123 A Street Sometown , CA 90266 Last Menstrual Period: Ordering Physician: DOB: 1953-10-10 Collection Times: Precision Analytical Age: 63 2016-10-02 06:00AM 2016-10-02 08:00AM Gender: Female 2016-10-01 06:00PM 2016-10-01 10:00PM 2016-10-02 02:00AM Hormone Testing Summary Key (how to read the results): Sex Hormones See Pages 2 and 3 for a thorough breakdown of sex hormone metabolites opausa n l R e a m n e g 1.8 4.5 6.0 2.3 14.0 r 5.1 2.8 1.5 P e patient low limit high limit 20.0 result 0.2-0.7 0.3-2.0 Postmenopausal range Estradiol(E2) Progesterone Testosterone (Serum Equivalent, ng/mL) Progesterone Serum Equivalent is a calculated value based on urine pregnanediol. Adrenal Hormones See pages 4 and 5 for a more complete breakdown of adrenal hormones Total DHEA Production 300 500 3000 Age Range 2516 Daily Free Cortisol Pattern 20-39 1300-3000 240 40-60 750-2000 (ng/mg) >60 500-1200 Total DHEA Production (DHEAS + Etiocholanolone + Androsterone) 180 High Range Limit 120Cortisol 80 52 2750 5930 60 230 6500 Patient Values Low Range Limit 24hr Free Cortisol cortisol Metabolized Cortisol (THF+THE) 0 (A+B+C+D) metabolism (Total Cortisol Production) Waking (A) Morning (B) Afternoon (C) Night (D) Free cortisol best reflects tissue levels. Metabolized cortisol best reflects total cortisol production. The following videos (which can also be found on the website under the listed names along with others) may aid your understanding: DUTCH Complete Overview Estrogen Tutorial Female Androgen Tutorial Cortisol Tutorial PLEASE BE SURE TO READ BELOW FOR A NY SPECIFIC LA B COMMENTS. -
Ultrasound Guided Femoral Nerve Block
Ultrasound Guided Femoral Nerve Block Michael Blaivas, MD, FACEP, FAIUM Clinical Professor of Medicine University of South Carolina School of Medicine AIUM, Third Vice President President, Society for Ultrasound Medical Education Past President, WINFOCUS Editor, Critical Ultrasound Journal Sub-specialty Editor, Journal of Ultrasound in Medicine Emergency Medicine Atlanta, Georgia [email protected] Disclosures • No relevant disclosures to lecture Objectives • Discuss anatomy of femoral nerve • Discuss uses of femoral nerve block classically and 3-in-1 variant • Discuss technique of femoral nerve blockade under ultrasound • Discuss pitfalls and potential errors Femoral Nerve Block Advantages • Many uses of regional nerve blocks • Avoid narcotics and their complications • Allow for longer term pain control • Can be used in patients unfit for sedation – Poor lung health – Hypotensive – Narcotic dependence or sensitivity Femoral Nerve Blocks • Wide variety of potential indications for a femoral nerve block – Hip fracture – Knee dislocation – Femoral fracture – Laceration repair – Burn – Etc. Nerve Blocks in Community vs. Academic Setting • Weekend stays • Night time admissions • Time to get consult and clear • Referral and admission patters • All of these factors can lead to patients spending considerable time prior to OR • Procedural sedation vs. block Femoral Nerve Blocks • Several basic principles with US also • Specialized needles +/- • No nerve stimulator • Can see nerve directly and inject directly around target nerve or nerves • Only -
Human Plasma and Recombinant Hemopexins: Heme Binding Revisited
International Journal of Molecular Sciences Article Human Plasma and Recombinant Hemopexins: Heme Binding Revisited Elena Karnaukhova 1,*, Catherine Owczarek 2, Peter Schmidt 2, Dominik J. Schaer 3 and Paul W. Buehler 4,5,* 1 Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA 2 CSL Limited, Bio21 Institute, Parkville, Victoria 3010, Australia; [email protected] (C.O.); [email protected] (P.S.) 3 Division of Internal Medicine, University Hospital of Zurich, 8091 Zurich, Switzerland; [email protected] 4 Department of Pathology, The University of Maryland School of Medicine, Baltimore, MD 21201, USA 5 The Center for Blood Oxygen Transport and Hemostasis, Department of Pediatrics, The University of Maryland School of Medicine, Baltimore, MD 21201, USA * Correspondence: [email protected] (E.K.); [email protected] (P.W.B.) Abstract: Plasma hemopexin (HPX) is the key antioxidant protein of the endogenous clearance pathway that limits the deleterious effects of heme released from hemoglobin and myoglobin (the term “heme” is used in this article to denote both the ferrous and ferric forms). During intra-vascular hemolysis, heme partitioning to protein and lipid increases as the plasma concentration of HPX declines. Therefore, the development of HPX as a replacement therapy during high heme stress could be a relevant intervention for hemolytic disorders. A logical approach to enhance HPX yield involves recombinant production strategies from human cell lines. The present study focuses on a biophysical assessment of heme binding to recombinant human HPX (rhHPX) produced in the Expi293FTM (HEK293) cell system. -
The Steroid Metabolome in Men with Mood and Anxiety Disorders
Physiol. Res. 64 (Suppl. 2): S275-S282, 2015 https://doi.org/10.33549/physiolres.933067 The Steroid Metabolome in Men With Mood and Anxiety Disorders M. DUŠKOVÁ1, M. HILL1, M. BIČÍKOVÁ1, M. ŠRÁMKOVÁ1, D. ŘÍPOVÁ2, P. MOHR2, L. STÁRKA1 1Institute of Endocrinology, Prague, Czech Republic, 2National Institute of Mental Health, Klecany, Czech Republic Received May 5, 2015 Accepted May 20, 2015 Summary many other hormones and various factors have been The mood and behavior of individuals result from an orchestra of identified as modulators of mood and behavior in such many factors. Among them steroids play an important role; disorders. Recent studies have described the role of brain- however, only several common hormones have been investigated derived neurotrophic factor (BDNF) (Pluchino et al. in this respect. It has been demonstrated that some steroid 2013, Numakawa et al. 2014), thyroid hormones (Duntas metabolites long considered merely the products of steroid and Mails 2013), inflammation (Halaris 2013), immunity hormone metabolism in fact possess considerable activity in the (Pitychoutis and Papadopoulou-Daifoti 2010), melatonin CNS. For this reason we studied the steroid metabolome (Boyce and Hopwood 2013), oxytocin and vasopressin including 50 analytes in 20 men with depression, 20 men with (Scantamburlo et al. 2009, Matsuzaki et al. 2012), the anxiety and 30 healthy controls. Significant differences were renin-angiotensin-aldosterone system (Franklin et al. found not only between controls and men with either depression 2012, Murck et al. 2012), the cannabinoid system or anxiety, but also between men with depression and anxiety. (Martykánová 2010, Gorzalka and Hill 2011, Smaga et Particularly striking were those steroids until now not generally al. -
Treatment of Equine Gastric Impaction by Gastrotomy R
EQUINE VETERINARY EDUCATION / AE / april 2011 169 Case Reporteve_165 169..173 Treatment of equine gastric impaction by gastrotomy R. A. Parker*, E. D. Barr† and P. M. Dixon Dick Vet Equine Hospital, University of Edinburgh, Easter Bush Veterinary Centre, Midlothian; and †Bell Equine Veterinary Clinic, Mereworth, UK. Keywords: horse; colic; gastric impaction; gastrotomy Summary Edinburgh with a deep traumatic shoulder wound of 24 h duration. Examination showed a mildly contaminated, A 6-year-old Warmblood gelding was referred for treatment of 15 cm long wound over the cranial aspect of the left a traumatic shoulder wound and while hospitalised developed scapula that transected the brachiocephalicus muscle a large gastric impaction which was unresponsive to and extended to the jugular groove. The horse was sound medical management. Gastrotomy as a treatment for gastric at the walk and ultrasonography showed no abnormalities impactions is rarely attempted in adult horses due to the of the bicipital bursa. limited surgical access to the stomach. This report describes The wound was debrided and lavaged under standing the successful surgical treatment of the impaction by sedation and partially closed with 2 layers of 3 metric gastrotomy and management of the post operative polyglactin 910 (Vicryl)1 sutures in the musculature and complications encountered. simple interrupted polypropylene (Prolene)1 skin sutures, leaving some ventral wound drainage. Sodium benzyl Introduction penicillin/Crystapen)2 (6 g i.v. q. 8 h), gentamicin (Gentaject)3 (6.6 mg/kg bwt i.v. q. 24 h), flunixin 4 Gastric impactions are rare in horses but, when meglumine (Flunixin) (1.1 mg/kg bwt i.v. -
Mod Signs up for 200 Ocelot Light Protected Patrol Vehicles
Force Protection Europe Limited Ricardo plc Midlands Technical Centre, Shoreham Technical Centre Southam Road, Radford Semele, Shoreham-by-Sea Leamington Spa, CV31 1FQ West Sussex BN43 5FG Tel: +44 (0)1926 319 494 Tel: +44 (0)1273 455611 MoD signs up for 200 Ocelot light protected patrol vehicles – Contract award gives Force Protection Europe two industry firsts – Force Protection Europe has signed a contract with the UK MoD to supply an order of 200 Ocelots, and an initial spares package, for the Light Protected Patrol Vehicles (LPPV) programme. The contract is valued at approximately £180 million and delivery of the vehicles is scheduled to be completed by Spring 2012. The announcement means that Force Protection Europe’s unique new light protected patrol vehicle can now lay claim to two important industry firsts. The Ocelot will be the first ever British designed and built protected patrol vehicle to include a fully composite pod to protect the occupants. This innovative module has been developed by drawing on technology from the motorsports industry. Ocelot will also be the first British military vehicle to accommodate the MoD’s new Generic Vehicle Architecture (GVA) requirements. The objective of the GVA project is to create a single, standard digital electronic and electrical architecture for UK vehicles that will enable crew to manage power and handle data efficiently on the vehicle, and for the vehicle to be easily adapted when the need arises. The award is also a significant boost to Force Protection Europe’s supply chain which is 90 percent British by value. Designed, developed and built in the UK by survivability specialist Force Protection Europe and automotive specialist Ricardo plc, together with Team Ocelot partners Thales, QinetiQ, Formaplex, DSG and Sula, Ocelot is the most highly protected and agile vehicle of its size and weight that is available today. -
Increased and Mistimed Sex Hormone Production in Night Shift Workers
Published OnlineFirst March 3, 2015; DOI: 10.1158/1055-9965.EPI-14-1271 Research Article Cancer Epidemiology, Biomarkers Increased and Mistimed Sex Hormone Production & Prevention in Night Shift Workers Kyriaki Papantoniou1,2,3,4, Oscar J. Pozo2, Ana Espinosa1,2,3,4, Josep Marcos2,3, Gemma Castano-Vinyals~ 1,2,3,4, Xavier Basagana~ 1,2,3,4, Elena Juanola Pages 5, Joan Mirabent6,7, Jordi Martín8, Patricia Such Faro9, Amparo Gasco Aparici10, Benita Middleton11, Debra J. Skene11, and Manolis Kogevinas1,2,3,4,12 Abstract Background: Night shift work has been associated with Results: Night workers had higher levels of total progestagens an increased risk for breast and prostate cancer. The effect [geometric mean ratio (GMR) 1.65; 95% confidence intervals of circadian disruption on sex steroid production is a pos- (CI), 1.17–2.32] and androgens (GMR: 1.44; 95% CI, 1.03–2.00), sible underlying mechanism, underinvestigated in hum- compared with day workers, after adjusting for potential con- ans. We have assessed daily rhythms of sex hormones founders. The increased sex hormone levels among night and melatonin in night and day shift workers of both shift workers were not related to the observed suppression of sexes. 6-sulfatoxymelatonin. Peak time of androgens was significantly Methods: We recruited 75 night and 42 day workers, ages later among night workers, compared with day workers (testos- 22 to 64 years, in different working settings. Participants terone: 12:14 hours; 10:06-14:48 vs. 08:35 hours; 06:52-10:46). collected urine samples from all voids over 24 hours on a Conclusions: We found increased levels of progestagens and working day. -
The International Student Journal of Nurse Anesthesia
Volume 15 Issue 1 Spring 2016 The International Student Journal of Nurse Anesthesia TOPICS IN THIS ISSUE Ondansetron to prevent SAB-induced Hypotension Hyperthermic Intraperitoneal Chemotherapy Carnitine Palmitoyltransferase Deficiency Adductor Canal vs. Femoral Nerve Block Ketamine Induction for Awake Intubation Airway Management for Tracheostomy TIVA for Gastroenterology Procedures Hematoma Following Thyroidectomy Tranexamic Acid in Trauma Tracheoesophageal Fistula Reintubation in the PACU Venous Air Embolism Emergence Delirium Preventing OR Fires INTERNATIONAL STUDENT JOURNAL OF NURSE ANESTHESIA Vol. 15 No. 1 Spring 2016 Editor Vicki C. Coopmans, CRNA, PhD Associate Editor Julie A. Pearson, CRNA, PhD Editorial Board Laura Ardizzone, CRNA, DNP Memorial Sloan Kettering Cancer Center; NY, NY MAJ Sarah Bellenger, CRNA, MSN, AN Darnall Army Medical Center; Fort Hood, TX Laura S. Bonanno, CRNA, DNP Louisiana State University Health Sciences Center Carrie C. Bowman Dalley, CRNA, MS Georgetown University Marianne Cosgrove, CRNA, DNAP Yale-New Haven Hospital School of Nurse Anesthesia LTC Denise Cotton, CRNA, DNAP, AN Winn Army Community Hospital; Fort Stewart, GA Janet A. Dewan, CRNA, PhD Northeastern University Kären K. Embrey CRNA, EdD University of Southern California Millikin University and Rhonda Gee, CRNA, DNSc Decatur Memorial Hospital Marjorie A. Geisz-Everson CRNA, PhD University of Southern Mississippi Johnnie Holmes, CRNA, PhD Naval Hospital Camp Lejeune Anne Marie Hranchook, CRNA, DNP Oakland University-Beaumont Donna Jasinski, -
Femoral and Sciatic Nerve Blocks for Total Knee Replacement in an Obese Patient with a Previous History of Failed Endotracheal Intubation −A Case Report−
Anesth Pain Med 2011; 6: 270~274 ■Case Report■ Femoral and sciatic nerve blocks for total knee replacement in an obese patient with a previous history of failed endotracheal intubation −A case report− Department of Anesthesiology and Pain Medicine, School of Medicine, Catholic University of Daegu, Daegu, Korea Jong Hae Kim, Woon Seok Roh, Jin Yong Jung, Seok Young Song, Jung Eun Kim, and Baek Jin Kim Peripheral nerve block has frequently been used as an alternative are situations in which spinal or epidural anesthesia cannot be to epidural analgesia for postoperative pain control in patients conducted, such as coagulation disturbances, sepsis, local undergoing total knee replacement. However, there are few reports infection, immune deficiency, severe spinal deformity, severe demonstrating that the combination of femoral and sciatic nerve blocks (FSNBs) can provide adequate analgesia and muscle decompensated hypovolemia and shock. Moreover, factors relaxation during total knee replacement. We experienced a case associated with technically difficult neuraxial blocks influence of successful FSNBs for a total knee replacement in a 66 year-old the anesthesiologist’s decision to perform the procedure [1]. In female patient who had a previous cancelled surgery due to a failed tracheal intubation followed by a difficult mask ventilation for 50 these cases, peripheral nerve block can provide a good solution minutes, 3 days before these blocks. FSNBs were performed with for operations on a lower extremity. The combination of 50 ml of 1.5% mepivacaine because she had conditions precluding femoral and sciatic nerve blocks (FSNBs) has frequently been neuraxial blocks including a long distance from the skin to the used for postoperative pain control after total knee replacement epidural space related to a high body mass index and nonpalpable lumbar spinous processes. -
MASSHEALTH TRANSMITTAL LETTER LAB-22 July 2002 TO
Commonwealth of Massachusetts Executive Office of Health and Human Services Division of Medical Assistance 600 Washington Street Boston, MA 02111 www.mass.gov/dma MASSHEALTH TRANSMITTAL LETTER LAB-22 July 2002 TO: Independent Clinical Laboratories Participating in MassHealth FROM: Wendy E. Warring, Commissioner RE: Independent Clinical Laboratory Manual (Laboratory HCPCS) The federal government has revised the HCFA Common Procedure Coding System (HCPCS) for MassHealth billing. This letter transmits changes for your provider manual that contain the new and revised codes. The revised Subchapter 6 is effective for dates of service on or after April 30, 2002. The codes introduced under the 2002 HCPCS code book are effective for dates of service on or after April 30, 2002. We will accept either the new or the old codes for dates of service through July 28, 2002. For dates of service on or after July 29, 2002, you must use the new codes to receive payment. If you wish to obtain a fee schedule, you may purchase Division of Health Care Finance and Policy regulations from either the Massachusetts State Bookstore or from the Division of Health Care Finance and Policy (see addresses and telephone numbers below). You must contact them first to find out the price of the publication. The Division of Health Care Finance and Policy also has the regulations available on disk. The regulation title for laboratory is 114.3 CMR 20.00: Laboratory. Massachusetts State Bookstore Division of Health Care Finance and Policy State House, Room 116 Two Boylston Street -
Jared J. Wallen MD MBA
Jared J. Wallen MD MBA Education Post American Board of Urology – Board Certification (Expires 02/28/2029) Massachusetts Institute of Technology – Certificate Commercial Real Estate Analysis and Investing (Class of 2019) London School of Economics and Political Science – Certificate Masters of Business Administration Essentials (Class of 2019) Masters in Real Estate Fortune Builders (Class of 2020) Florida Real Estate Sales Associate License Certification (09/2020) Designation as National Commercial Real Estate Advisor and Certified Real Estate Investment Planning Specialist (01/2021) Fell. Boston Scientific Men’s Sexual Health Research Fellow, Class of 2018 P.G. University of Southern Florida – Morsani College of Medicine, Urologic Surgery Residency, Class of 2017 University of Southern Florida – Morsani College of Medicine, General Surgery Internship, Class of 2013 M.D. Rush Medical College, Doctorate in Medicine, Class of 2012 B.S. University of Illinois Urbana/Champaign, Bachelors with Honors in Molecular and Cellular Biology and Psychology, Class of 2008 A.A. Rock Valley Community College, Associates in Arts, Concentration in Psychology, Class of 2004 Experience • Manager and Lead Urologic Surgeon – YOU & WEE Urologic 10/2020 – present Surgery and Wellness • Manager – RUFF & RESTORE EcoFriendly Properties 11/2019 – present • Founder Men’s Health Survivorship Foundation 10/2018 - present • Board Certified Urologic Surgeon – Advent Health Tampa 10/2017 - 10/2020 Physician Group Urology • Adjunct Faculty - Lincoln Memorial University DCOM 02/2018 – 10/2020 • Consultant Boston Scientific 05/2019 – present 05/2019 - present • Consultant Myriad Genetics • Aquatics Student Coordinator Campus Recreation at University 06/2006 - 06/2008 of Illinois • Assistant Store Manager Valvoline Instant Oil Change 06/2001 - 08/2004 Jared J.