Stress and Inflammatory Skin Disorders: a Review of Non-Pharmacologic Treatments

Total Page:16

File Type:pdf, Size:1020Kb

Stress and Inflammatory Skin Disorders: a Review of Non-Pharmacologic Treatments JAOCDJournal Of The American Osteopathic College Of Dermatology Volume 26 pg. 12 Stress and Inflammatory Skin Disorders: A Review of Non-Pharmacologic Treatments Also in this issue: last modified on September 24, 2013 1:07 PM JOURNAL OF THE AMERICAN OSTEOPATHIC COLLEGE OF DERMATOLOGY Page 1 JOURNAL OF THE AMERICAN OSTEOPATHIC COLLEGE OF DERMATOLOGY 2012-2013 OFFICERS PRESIDENT David L. Grice, DO, FAOCD PRESIDENT-ELECT Suzanne Sirota-Rozenberg, DO, FAOCD FIRST VICE-PRESIDENT Rick J. Lin, DO, FAOCD SECOND VICE-PRESIDENT Alpesh Desai, DO, FAOCD THIRD VICE-PRESIDENT Editor-in-Chief Karthik Krishnamurthy, DO, FAOCD Karthik Krishnamurthy, DO IMMEDIATE PAST-PRESIDENT Bradley Glick, DO, FAOCD TRUSTEES Danica Alexander, DO, FAOCD Reagan Anderson, DO, FAOCD Sponsors: Mark A. Kuriata, DO, FAOCD Daniel Ladd, DO, FAOCD Bayer John P. Minni, DO, FAOCD Bryan Sands, DO, FAOCD AuroraDx SECRETARY-TREASURER Medicis Jere J. Mammino, DO, FAOCD Ranbaxy EXECUTIVE DIRECTOR Marsha A. Wise, B.S. JAOCD Founding Sponsor AOCD • 2902 N. Baltimore St. • Kirksville, MO 63501 800-449-2623 • FAX: 660-627-2623 www.aocd.org COPYRIGHT AND PERMISSION: Written permission must be obtained from the Journal of the American Osteopathic College of Dermatology for copying or reprinting text of more than half a page, tables or figures. Permissions are normally granted contingent upon similar permission from the author(s), inclusion of acknowledgement of the original source, and a payment of $15 per page, table or figure of reproduced material. Permission fees are waived for authors wishing to reproduce their own articles. Request for permission should be directed to JAOCD c/o AOCD, PO Box 7525, Kirksville, MO 63501. Copyright © 2003 by the Journal of the American Osteopathic College of Dermatology Print and layout by: S&S Printing and Graphics LLC, 401 N. Marion St., Kirksville, MO 63501 Copy editing by: Julia Layton, Freelance Writing and Editing Cover image by: Vikram Krishnamurthy, MD, Chicago, IL Page 2 JOURNAL OF THE AMERICAN OSTEOPATHIC COLLEGE OF DERMATOLOGY JOURNAL OF THE AMERICAN OSTEOPATHIC COLLEGE OF DERMATOLOGY Table of Contents Volume 26 JAOCD Editors ............................................................................................................................................................................................ 4 Letter from the Editor-in-Chief ................................................................................................................................................................... 5 Letter from the Executive Director ............................................................................................................................................................... 6 Letter from the President .............................................................................................................................................................................. 7 FEATURE ARTICLE: Stress and Inflammatory Skin Disorders: A Review of Non-Pharmacologic Treatment Options Monica Huynh, BA, John Koo, MD ........................................................................................................................................................ 12 EdiTOr’S PicKS: Old World meets New World Leishmaniasis: Leishmania tropica in Florida Ann Mazor-Reed, DO, Jacqueline A. Thomas, DO, FAOCD .................................................................................................................... 15 Use of Acitretin in a Patient with Multiple Squamous Cell Carcinomas: A Case Report and Literature Review Dorene Niv, BS, Patrick Keehan, DO, FAOCD ....................................................................................................................................... 18 Cutaneous Manifestation of Churg-Strauss Syndrome Holly Kanavy, DO, Cindy Hoffman, DO ................................................................................................................................................ 21 ORIGINAL ARTiclES AND CASE REPORTS Scalp Metastasis Heralding a Diagnosis of Breast Cancer: A Case Report and Discussion Mounir Wassef, DO, Robin Shecter, DO, FAOCD ................................................................................................................................... 24 Case Report: Diffuse Bullous Eruption Following Antibiotic Use Capt. Shannon Buck, DO, Lt. Col. Erika Hill, MD, Col. (Ret) Wayne Sumpter, MD ................................................................................ 26 Atypical Fibroxanthoma with Osteoclast-like Giant Cells: Report of Two Cases Viktoryia Kazlouskaya, MD, PhD, Vladyslava Doktor, MA, Elen Blochin, MD, PhD, Dirk Elston, MD ................................................... 28 Primary Cutaneous Adenosquamous Carcinoma Treated with Mohs Donna D. Tran, DO, Brooke Walls, DO, Richard Miller, DO, FAOCD ................................................................................................... 30 Lupus Panniculitis of the Lower Extremities: A Case Report and Review of the Literature Dustin Portela, H-BS, Paul M. Bedocs, DO, Melissa Piliang, MD ........................................................................................................... 31 Oral and Cutaneous Lichenoid Drug Eruption Secondary to Imatinib Mesylate: A Case Report and Review of the Literature Kristen Suchniak, MD, Gregg Severs, DO ............................................................................................................................................... 33 Dercum’s Disease Treated by Coolsculpting: A Case Report Jonathan S. Crane, DO, FAOCD, J. Kate Jackson, PA-C, Louis I. Padgett, BS .......................................................................................... 35 The Companion: A Desmoplastic Trichoepithelioma Arising within a Melanocytic Nevus Peter Knabel, DO, Lloyd Cleaver, DO, FAOCD ...................................................................................................................................... 36 Atypical Adult-onset Pityriasis Rubra Pilaris and Recurrent Corneal Ulcerations Natalie Edgar, BS, David Eslicker, DO, FAOCD, Henry Haskell, MD .................................................................................................... 38 Granular Parakeratosis Treatment with Tacrolimus 0.1% Ointment: A Case Presentation and Discussion Bertha Baum, DO, Stanley Skopit, DO, MSE, FAOCD .......................................................................................................................... 40 Hyperpigmentation in a 51-year-old Caucasian Female William Bethea, DO, Bryce Desmond, BS, Steven K. Grekin, DO ............................................................................................................ 42 JOURNAL OF THE AMERICAN OSTEOPATHIC COLLEGE OF DERMATOLOGY Page 3 Editor-In-Chief Founding Editor Assistant Editor Karthik Krishnamurthy, DO Jay Gottleib, DO Julia Layton, BA, MFA Associate Editors Aaron Bruce, DO Michelle Foley, DO Michael Scott, DO Scott Wickless, DO Loveland, CO Ormond Beach, FL Seattle, WA Durango, CO Editorial Board Sami Abbasi, DO Marcus Goodman, DO Rick Lin, DO Adriana Ros, DO Brownstown, MI Roswell, GA McAllen, TX Clifton, NJ Brad Abrams, DO Melinda Greenfield, DO Chava Lustig, DO Richard Rudnicki, DO Sarasota, FL Albany. GA Weston, FL Mesquite, TX Derrick Adams, DO Denise Guevara, DO Jere Mammino, DO Amara Sayed, DO Red Bluff, CA Weston, FL Winter Springs, FL San Marcos, TX Brooke Bair, DO Andrew Hanly, MD Chris Manlio, DO Joseph Brant Schneider, DO Jacksonville, FL Miami, FL Loxahatchee, FL Shawnee Mission, KS Kevin Belasco, DO Joel Harris, DO John Minni, DO Gregg Severs, DO Milwaukee, WI Madison Heights, MI Port St. Lucie, FL Scranton, PA Brett Bender, DO Heather Higgins, DO Tony Nakhla, DO Sean Stephenson, DO Farmington Hills, MI Troy, MI Orange County, CA Troy, MI Richard Bernert, MD David Horowitz, DO Navid Nami, DO Jacqueline Thomas, DO Scottsdale, AZ Torrence, CA Newport Beach, CA Fort Lauderdale, FL Ryan Carlson, DO Jocelyn LaRocque, DO Jon Keeling, DO Jim Towry, DO Hilliard, OH Charlotte, NC Lexington, KY Ocala, FL Michael P. Conroy, MD Matt Leavitt, DO Dimitria Papadopoulos, DO Columbus, OH Maitland, FL Bellmore, NY Not pictured: Iqbal Bukhari, MD Alkhobar, Saudi Arabia Matther Elias, DO Mark Lebwohl, MD John Perrotto, DO Lighthouse Point, FL New York, NY West Palm Beach, FL Merrick Elias, DO Angela Leo, DO Stephen Purcell, DO Delray Beach, FL New York, NY Allentown, PA Brad Glick, DO Scott Lim, DO Andrew Racette, DO Margate, FL Erie, PA Phoenix, AZ Page 4 JAOCD EdITORS LETTER FROM THE EDITOR-IN-CHIEF Karthik Krishnamurthy, DO, FAOCD Editor-in-Chief Dear JAOCD Readership, On August 1, 2013, under the Physician Payment Sunshine Act (PPSA), “industry” must begin collating information regarding its relationships with physicians. Starting in March 2014, “industry” will begin reporting “payment or other transfer of value” to the Department of Health and Human Resources. What does this mean? Begotten by the Patient Protection and Affordable Health Care Act of 2010, the intention of PPSA is to ensure transparency. Reporting will be facilitated through CMS.gov (Centers for Medicare and Medicaid Services), and it is imperative that all physicians register with the service in order to receive notifications and track and verify “transactions,” as there will be a 45-day window to review or challenge individual entries. “Industry” includes pharmaceutical, medical-device, biological and medical-supply companies. The definition of “payment
Recommended publications
  • Paraneoplastic Syndrome Presenting As Giant Porokeratosis in a Patient with Nasopharyngeal Cancer
    Paraneoplastic Syndrome Presenting As Giant Porokeratosis in A Patient with Nasopharyngeal Cancer Fitri Azizah, Sonia Hanifati, Sri Adi Sularsito, Lili Legiawati, Shannaz Nadia Yusharyahya, Rahadi Rihatmadja Department of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia / Dr. Cipto Mangunkusumo National General Hospital Keywords: porokeratosis, giant porokeratosis, paraneoplastic syndrome, nasopharyngeal Abstract: Giant porokeratosis is a rare condition in which the hyperkeratotic plaques of porokeratosis reach up to 20 cm in diameter. Porokeratosis is characterized clinically by hyperkeratotic papules or plaques with a thread-like elevated border. Although rare, porokeratosis has been reported in conjunction with malignancies suggesting a paraneoplastic nature. Associated malignancies reported were hematopoietic, hepatocellular, and cholangiocarcinoma. We report a case of giant porokeratosis in a patient with nasopharyngeal cancer responding to removal of the primary cancer by chemoradiotherapy. 1 INTRODUCTION regress completely after the treatment of malignancy, suggestive of paraneoplastic syndrome. Porokeratosis is a chronic progressive disorder of keratinization, characterized by hyperkeratotic papules or plaques surrounded by a thread-like 2 CASE elevated border corresponds to a typical histologic hallmark, the cornoid lamella . O regan, 2012) There Mr. SS, 68-year-old, was referred for evaluation of are at least six clinical variants of porokeratosis pruritic, slightly erythematous plaques with raised, recognized with known genetic disorder.1 Some hyperpigmented border of one and a half year clinical variant of porokeratosis has been reported in duration on the extensor surface of both legs. The the setting of immunosuppressive conditions, organ lesions shown minimal response to potent topical transplantation, use of systemic corticosteroids, and corticosteroids and phototherapy given during the infections, suggesting that impaired immunity may last 8 months in another hospital.
    [Show full text]
  • Pediatric and Adolescent Dermatology
    Pediatric and adolescent dermatology Management and referral guidelines ICD-10 guide • Acne: L70.0 acne vulgaris; L70.1 acne conglobata; • Molluscum contagiosum: B08.1 L70.4 infantile acne; L70.5 acne excoriae; L70.8 • Nevi (moles): Start with D22 and rest depends other acne; or L70.9 acne unspecified on site • Alopecia areata: L63 alopecia; L63.0 alopecia • Onychomycosis (nail fungus): B35.1 (capitis) totalis; L63.1 alopecia universalis; L63.8 other alopecia areata; or L63.9 alopecia areata • Psoriasis: L40.0 plaque; L40.1 generalized unspecified pustular psoriasis; L40.3 palmoplantar pustulosis; L40.4 guttate; L40.54 psoriatic juvenile • Atopic dermatitis (eczema): L20.82 flexural; arthropathy; L40.8 other psoriasis; or L40.9 L20.83 infantile; L20.89 other atopic dermatitis; or psoriasis unspecified L20.9 atopic dermatitis unspecified • Scabies: B86 • Hemangioma of infancy: D18 hemangioma and lymphangioma any site; D18.0 hemangioma; • Seborrheic dermatitis: L21.0 capitis; L21.1 infantile; D18.00 hemangioma unspecified site; D18.01 L21.8 other seborrheic dermatitis; or L21.9 hemangioma of skin and subcutaneous tissue; seborrheic dermatitis unspecified D18.02 hemangioma of intracranial structures; • Tinea capitis: B35.0 D18.03 hemangioma of intraabdominal structures; or D18.09 hemangioma of other sites • Tinea versicolor: B36.0 • Hyperhidrosis: R61 generalized hyperhidrosis; • Vitiligo: L80 L74.5 focal hyperhidrosis; L74.51 primary focal • Warts: B07.0 verruca plantaris; B07.8 verruca hyperhidrosis, rest depends on site; L74.52 vulgaris (common warts); B07.9 viral wart secondary focal hyperhidrosis unspecified; or A63.0 anogenital warts • Keratosis pilaris: L85.8 other specified epidermal thickening 1 Acne Treatment basics • Tretinoin 0.025% or 0.05% cream • Education: Medications often take weeks to work AND and the patient’s skin may get “worse” (dry and red) • Clindamycin-benzoyl peroxide 1%-5% gel in the before it gets better.
    [Show full text]
  • A Single Case Report of Granular Cell Tumor of the Tongue Successfully Treated Through 445 Nm Diode Laser
    healthcare Case Report A Single Case Report of Granular Cell Tumor of the Tongue Successfully Treated through 445 nm Diode Laser Maria Vittoria Viani 1,*, Luigi Corcione 1, Chiara Di Blasio 2, Ronell Bologna-Molina 3 , Paolo Vescovi 1 and Marco Meleti 1 1 Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy; [email protected] (L.C.); [email protected] (P.V.); [email protected] (M.M.) 2 Private practice, Centro Medico Di Blasio, 43121 Parma; Italy; [email protected] 3 Faculty of Dentistry, University of the Republic, 14600 Montevideo, Uruguay; [email protected] * Correspondence: [email protected] Received: 10 June 2020; Accepted: 11 August 2020; Published: 13 August 2020 Abstract: Oral granular cell tumor (GCT) is a relatively rare, benign lesion that can easily be misdiagnosed. Particularly, the presence of pseudoepitheliomatous hyperplasia might, in some cases, lead to the hypothesis of squamous cell carcinoma. Surgical excision is the treatment of choice. Recurrence has been reported in up to 15% of cases treated with conventional surgery. Here, we reported a case of GCT of the tongue in a young female patient, which was successfully treated through 445 nm diode laser excision. Laser surgery might reduce bleeding and postoperative pain and may be associated with more rapid healing. Particularly, the vaporization effect on remnant tissues could eliminate GCT cells on the surgical bed, thus hypothetically leading to a lower rate of recurrence. In the present case, complete healing occurred in 1 week, and no recurrence was observed after 6 months. Laser surgery also allows the possibility to obtain second intention healing.
    [Show full text]
  • Download PDF (Inglês)
    Revista6Vol89ingles_Layout 1 10/10/14 11:08 AM Página 1003 WHAT IS YOUR DIAGNOSIS? 1003 s Case for diagnosis* João Roberto Antonio1 Larissa Cannizza Pacheco de Lucca1 Mariana Perez Borim1 Natália Cristina Pires Rossi1 Guilherme Bueno de Oliveira1 DOI: http://dx.doi.org/10.1590/abd1806-4841.20143156 CASE REPORT A 60-year-old woman reports a 5-year history of violaceous and intensely pruritic lesions on the dorsum and scalp, associated with a 2-year history of hair loss. She also reports decreased hair growth in the axillary and inguinal regions in the same period. Dermatological examination shows small, scaly, erythematous-violaceous, flat papules on the dorsal region; multifocal scarring alopecia areas, with smooth, bright and atrophic surface; discrete hair rarefaction in the axillary and inguinal regions; presence of longitu- FIGURE 2: dinal grooves and some depressions on the surface of Perifollicular the nail plate; no oral lesions (Figures 1 and 2). The erythema with desquamation at histopathology of the dorsal lesion is shown in figure the vertex of the 3A and that of the scalp is shown in figure 3B. scalp; cicatricial The treatment was performed using high- alopecia and potency corticoids and resulted, after three months, in smooth, bright and atrophic surface an improvement of pruritus and a slight lightening of the lesions. A FIGURE 1: B Cutaneous, erythematous- FIGURE 3: A. HE 200x. Interface dermatitis with lichenoid pattern purpuric lesions associated with dermo-epidermic detachment and lymphocytic on the infiltrate in band-like pattern in the upper dermis. B. HE 200x. dorsal region Detail of partially destroyed follicle, with perifollicular fibrosis and perivascular lymphocytic infiltrate Received on 19.09.2013.
    [Show full text]
  • ORIGINAL ARTICLE a Clinical and Histopathological Study of Lichenoid Eruption of Skin in Two Tertiary Care Hospitals of Dhaka
    ORIGINAL ARTICLE A Clinical and Histopathological study of Lichenoid Eruption of Skin in Two Tertiary Care Hospitals of Dhaka. Khaled A1, Banu SG 2, Kamal M 3, Manzoor J 4, Nasir TA 5 Introduction studies from other countries. Skin diseases manifested by lichenoid eruption, With this background, this present study was is common in our country. Patients usually undertaken to know the clinical and attend the skin disease clinic in advanced stage histopathological pattern of lichenoid eruption, of disease because of improper treatment due to age and sex distribution of the diseases and to difficulties in differentiation of myriads of well assess the clinical diagnostic accuracy by established diseases which present as lichenoid histopathology. eruption. When we call a clinical eruption lichenoid, we Materials and Method usually mean it resembles lichen planus1, the A total of 134 cases were included in this study prototype of this group of disease. The term and these cases were collected from lichenoid used clinically to describe a flat Bangabandhu Sheikh Mujib Medical University topped, shiny papular eruption resembling 2 (Jan 2003 to Feb 2005) and Apollo Hospitals lichen planus. Histopathologically these Dhaka (Oct 2006 to May 2008), both of these are diseases show lichenoid tissue reaction. The large tertiary care hospitals in Dhaka. Biopsy lichenoid tissue reaction is characterized by specimen from patients of all age group having epidermal basal cell damage that is intimately lichenoid eruption was included in this study. associated with massive infiltration of T cells in 3 Detailed clinical history including age, sex, upper dermis. distribution of lesions, presence of itching, The spectrum of clinical diseases related to exacerbating factors, drug history, family history lichenoid tissue reaction is wider and usually and any systemic manifestation were noted.
    [Show full text]
  • Subcutaneous Hemangiosarcoma: the First Report in Maltese Dog
    pISSN 1598-298X / eISSN 2384-0749 J Vet Clin 36(3) : 169-171 (2019) http://dx.doi.org/10.17555/jvc.2019.06.36.3.169 Subcutaneous Hemangiosarcoma: The First Report in Maltese Dog Ha-Jung Kim, Eun-Taek Hong and Guk-Hyun Suh1 Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju 500-757, Korea (Received: March 13, 2019 / Accepted: May 09, 2019) Abstract : Subcutanous hemangiosarcoma is rare malignant condition in dogs. An eleven-year-old neutered male Maltese was presented with multicentric cutaneous hemorrhagic nodules followed by lethargy. The patient showed regenerative anemia and thrombocytopenia with skyrocketing D-dimer, indicating that he had disseminated intravascular coagulation (DIC) on progress. Fine needle aspiration, histopathology, X-ray, and computed tomographic scanning ultimately diagnosed this patient as subcutaneous hemangiosarcoma with disseminated metastasis to the body. Unfortunately, the dog died due to side effects of anti-thrombotic therapy for DIC. This case report described a rare subcutaneous hemangiosarcoma in a Maltese dog. Key words : dog, skin neoplasms, hemangiosarcoma, disseminated intravascular coagulation, histopathology. Introduction had a 2 month history of multicentric cutaneous hemor- rhagic nodules initiated from his dorsum (Fig 1A and C). Hemangiosarcoma (a.k.a. malignant hemangioendotheli- There were no specific findings from skin examination such oma or angisarcoma) is an outbreak of tumor from endothe- as scraping or taping, and no bacteria or fungi were cultured lial cells which occurs more frequently in dogs than any from the lesions. On physical examination, he had a pale other species, accounting for 0.3% to 2.0% of all tumors in mucous membrane with bilateral ocular hemorrhage (Fig dogs with a high fatality rate (1,7).
    [Show full text]
  • Cosmetic Center May Newsletter
    Cosmetic Center May Newsletter DERMATOLOGY ASSOCIATES Keratosis Pilaris May specials “KP” Very common 10 % off Sunscreen skin condition characterized by 10% off Glytone KP Products tiny, hard 20% off Laser Hair Removal bumps. Glytone and Neostrata Peels– Purchase a package of 6 and get 1 Free It can be found on the outer Purchase a Facial and Receive a Free Skin Care Starter Kit arms, thighs, and sometimes Product of the Month Procedure of the Month the buttocks Tilley Hats Facials It is caused by the buildup of Lifetime Warranty Schedule an appointment today for dead skin Waterproof & Float an hour of pampering and (keratin) around relaxation. We will use products Many Different Sizes, Styles, and the hair follicle. suitable for your skin type and Colors to Choose From KP generally condition. gets worse in the SPF 50 winter and often clears in the summer. KP is self-limiting and disappears with age. KP can be treated with products. Mother’s Day is May 10 We have several products in the Relaxing Facials & Gift Certificates make great gifts! Cosmetic Center Mini Facials for the month of May only $45 to treat and help You can also shop ONLINE at Kingsportderm.com and have the items shipped. Melanoma Awareness Month More than 1 million cases of skin cancer are diagnosed in the United States each year, making skin cancer the most common cancer in the United States. ABCDEs of Melanoma Approximately 62,480 cases of melanoma will be A. If you draw a line diagnosed each year, nearly 8,420 cases will lead to deaths.
    [Show full text]
  • Features of Reactive White Lesions of the Oral Mucosa
    Head and Neck Pathology (2019) 13:16–24 https://doi.org/10.1007/s12105-018-0986-3 SPECIAL ISSUE: COLORS AND TEXTURES, A REVIEW OF ORAL MUCOSAL ENTITIES Frictional Keratosis, Contact Keratosis and Smokeless Tobacco Keratosis: Features of Reactive White Lesions of the Oral Mucosa Susan Müller1 Received: 21 September 2018 / Accepted: 2 November 2018 / Published online: 22 January 2019 © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract White lesions of the oral cavity are quite common and can have a variety of etiologies, both benign and malignant. Although the vast majority of publications focus on leukoplakia and other potentially malignant lesions, most oral lesions that appear white are benign. This review will focus exclusively on reactive white oral lesions. Included in the discussion are frictional keratoses, irritant contact stomatitis, and smokeless tobacco keratoses. Leukoedema and hereditary genodermatoses that may enter in the clinical differential diagnoses of frictional keratoses including white sponge nevus and hereditary benign intraepithelial dyskeratosis will be reviewed. Many products can result in contact stomatitis. Dentrifice-related stomatitis, contact reactions to amalgam and cinnamon can cause keratotic lesions. Each of these lesions have microscopic findings that can assist in patient management. Keywords Leukoplakia · Frictional keratosis · Smokeless tobacco keratosis · Stomatitis · Leukoedema · Cinnamon Introduction white lesions including infective and non-infective causes will be discussed
    [Show full text]
  • A New Insight on Atopic Skin Diathesis: Is It Correlated with the Severity of Melasma
    A New Insight on Atopic Skin Diathesis: Is It Correlated with the Severity of Melasma Danar Wicaksono1*, Rima Mustafa2, Sri Awalia Febriana1, Kristiana Etnawati1 1 Dermatovenereology Department, Faculty of Medicine Universitas Gadjah Mada – Dr. Sardjito General Hospital, Yogyakarta-Indonesia 2 Clinical Epidemiology and Biostatistics Unit, Faculty of Medicine Universitas Gadjah Mada –Dr. Sardjito General Hospital, Yogyakarta-Indonesia Keywords: Melasma, atopic skin diathesis (ASD), MASI score, atopic dermatitis (AD) Abstract: Melasma is a macular lesion of light brown to dark on the sun-exposed area, especially on the face. Atopic Skin Diathesis (ASD) is a clinical term to describe skin atopics with previous, present or future atopic dermatitis (AD). Dennie-Morgan infraorbital folds are secondary creases in the skin below the lower eyelids with a sensitivity of 78% and a specificity of 76% to diagnose AD. Melasma skin is characterized by impaired stratum corneum integrity and a delayed barrier recovery rate. Barrier dysfunction will stimulate keratinocyte to secrete keratinocyte-derived factor, which plays role in skin pigmentation process in melasma. To analyze correlation between ASD and Melasma Area Severity Index (MASI) score in melasma patient. This study is an observational analytic study with cross sectional design. Measurement of ASD and MASI score were done in 60 subjects with melasma who went to dermatology outpatient clinic Dr. Sardjito General Hospital from July 2017 to Januari 2018. The correlation between ASD and MASI score was analyzed using Pearson correlation. The result of this study showed no significant correlation between ASD and MASI scores (r: 0.02, p: 0,85). Crude Relative Risk (RR) for Dennie-Morgan infraorbital folds and MASI score was 4 (1.01-15.87).
    [Show full text]
  • Fundamentals of Dermatology Describing Rashes and Lesions
    Dermatology for the Non-Dermatologist May 30 – June 3, 2018 - 1 - Fundamentals of Dermatology Describing Rashes and Lesions History remains ESSENTIAL to establish diagnosis – duration, treatments, prior history of skin conditions, drug use, systemic illness, etc., etc. Historical characteristics of lesions and rashes are also key elements of the description. Painful vs. painless? Pruritic? Burning sensation? Key descriptive elements – 1- definition and morphology of the lesion, 2- location and the extent of the disease. DEFINITIONS: Atrophy: Thinning of the epidermis and/or dermis causing a shiny appearance or fine wrinkling and/or depression of the skin (common causes: steroids, sudden weight gain, “stretch marks”) Bulla: Circumscribed superficial collection of fluid below or within the epidermis > 5mm (if <5mm vesicle), may be formed by the coalescence of vesicles (blister) Burrow: A linear, “threadlike” elevation of the skin, typically a few millimeters long. (scabies) Comedo: A plugged sebaceous follicle, such as closed (whitehead) & open comedones (blackhead) in acne Crust: Dried residue of serum, blood or pus (scab) Cyst: A circumscribed, usually slightly compressible, round, walled lesion, below the epidermis, may be filled with fluid or semi-solid material (sebaceous cyst, cystic acne) Dermatitis: nonspecific term for inflammation of the skin (many possible causes); may be a specific condition, e.g. atopic dermatitis Eczema: a generic term for acute or chronic inflammatory conditions of the skin. Typically appears erythematous,
    [Show full text]
  • Frontiers in Dermatology and Venereology - a Series of Theme Issues in Relation to the 100-Year Anniversary of Actadv
    ISSN 0001-5555 ActaDV Volume 100 2020 Theme issue ADVANCES IN DERMATOLOGY AND VENEREOLOGY A Non-profit International Journal for Interdisciplinary Skin Research, Clinical and Experimental Dermatology and Sexually Transmitted Diseases Frontiers in Dermatology and Venereology - A series of theme issues in relation to the 100-year anniversary of ActaDV Official Journal of - European Society for Dermatology and Psychiatry Affiliated with - The International Forum for the Study of Itch Immediate Open Access Acta Dermato-Venereologica www.medicaljournals.se/adv ACTA DERMATO-VENEREOLOGICA The journal was founded in 1920 by Professor Johan Almkvist. Since 1969 ownership has been vested in the Society for Publication of Acta Dermato-Venereologica, a non-profit organization. Since 2006 the journal is published online, independently without a commercial publisher. (For further information please see the journal’s website https://www. medicaljournals.se/acta) ActaDV is a journal for clinical and experimental research in the field of dermatology and venereology and publishes high- quality papers in English dealing with new observations on basic dermatological and venereological research, as well as clinical investigations. Each volume also features a number of review articles in special areas, as well as Correspondence to the Editor to stimulate debate. New books are also reviewed. The journal has rapid publication times. Editor-in-Chief: Olle Larkö, MD, PhD, Gothenburg Former Editors: Johan Almkvist 1920–1935 Deputy Editors: Sven Hellerström 1935–1969
    [Show full text]
  • Immunologic Adverse Reactions of Β-Blockers and the Skin (Review)
    EXPERIMENTAL AND THERAPEUTIC MEDICINE 18: 955-959, 2019 Immunologic adverse reactions of β-blockers and the skin (Review) ALIN LAURENTIU TATU1, ALINA MIHAELA ELISEI1, VALENTIN CHIONCEL2, MAGDALENA MIULESCU3 and LAWRENCE CHUKWUDI NWABUDIKE4 1Medical and Pharmaceutical Research Unit/Competitive, Interdisciplinary Research Integrated Platform ‘Dunărea de Jos’, ReForm-UDJG; Research Centre in the Field of Medical and Pharmaceutical Sciences, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, ‘Dunărea de Jos’ University of Galați, 800010 Galati; 2Department of Cardio-Thoracic Pathology, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Phamacy, 050474 Bucharest; 3Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos University’ of Galati, 800010 Galati; 4Department of Diabetic Foot Care, ‘Prof. N. Paulescu’ National Institute of Diabetes, 011233 Bucharest, Romania Received September 11, 2018; Accepted November 16, 2018 DOI: 10.3892/etm.2019.7504 Abstract. β-Blockers are a widely utilised class of medica- use, as well as possible therapeutic approaches to these. This tion. They have been in use for a variety of systemic disorders short review will focus on those dermatoses resulting from including hypertension, heart failure and intention tremors. β-blocker use, which have an immunologic basis. Their use in dermatology has garnered growing interest with the discovery of their therapeutic effects in the treatment of haemangiomas, their potential positive effects in wound Contents healing, Kaposi sarcoma, melanoma and pyogenic granuloma, and, more recently, pemphigus. Since β-blockers are deployed 1. Introduction in a variety of disorders, which have cutaneous co-morbidities 2. Cutaneous side - effects of β-blockers such as psoriasis, their pertinence to dermatologists cannot be 3.
    [Show full text]