13th International Conference on Systems Biology August 19 – 23, 2012 Schedule of Events

SUNDAY, August 19 12:00 noon - 5:00 pm Registration Concert Hall Foyer

3:00 pm - 3:15 pm Opening Remarks and Welcome Concert Hall Charlie Boone, University of Toronto

3:15 pm - 4:15 pm Plenary Session 1 Concert Hall Chair: Brenda Andrews, University of Toronto

Keynote Lecture Exploring the sequence specificty of eukarytic DNA and RNA binding proteins. Timothy Hughes.

Keynote Lecture Unraveling principles of gene regulation using thousands of designed promoter sequences.

4:15 pm - 5:00 pm Special Lectures Concert Hall Chair: Charlie Boone, University of Toronto

Visualisations of DNA with Hollywood visual effects. Drew Berry.

Systems-Biology Applications of Imaging Flow Cytometry. Timothy Galitski.

5:00 pm - 5:30 pm Champagne Reception Concert Hall Foyer

5:30 pm - 6:00 pm Performance byTanya Tagaq Inuit throat singer Concert Hall

6:15 pm - 8:00 pm Opening Reception at the Donnelly Centre Donnelly Centre

MONDAY, August 20 9:00 am - 10:00 am Plenary Session II Concert Hall Chair: Fritz Roth, University of Toronto

Keynote Lecture Reading and Writing Omes. George Church.

Lecture Towards unification of genetic and hierarchy models of tumor heterogeneity. John Dick.

10:00 am - 10:30 am Special Lecture Chair: Corey Nislow, University of Toronto Carl Zimmer, Science Journalist, Birds and Bioterrorists: The (Un)natural History of Influenza

13th International Conference on Systems Biology August 19 – 23, 2012 Schedule of Events

10:30 am - 11:00 am Coffee Concert Hall Foyer

11:00 am - 12:40 pm Parallel Sessions The Carlu

Modeling 1 Round Room Chairs: Edda Klip, Humboldt University Berlin; and Sven Nelander, Uppsala University, Sweden Chemical Biology Sky Room Chairs: Minoru Yoshida, RIKEN Institute; Eric Brown, McMaster University; and Hiroyuki Osada, RIKEN, Japan Protein Pathway Engineering/Synthetic Biology 1 Concert Hall Chairs: Dev Sidhu, University of Toronto; and Jim Wells, University of California, San Francisco

12:45 pm - 2:00 pm Lunch Concert Hall Foyer

2:00 pm - 3:40 pm Parallel Sessions The Carlu

Computational Tools/Algorithms Sky Room Chairs: Kris Gunsalas, New York University; and , Princeton University Metabolomics Round Room Chairs: Amy Caudy, University of Toronto; and Balázs Papp, Biological Research Center Hungary Stem and Cancer Cell Systems Biology Concert Hall Chairs: Jason Moffat, University of Toronto; and Jussi Taipale, Karolinska Institutet Concert Hall Foyer 3:45 pm - 4:15 pm Coffee Concert Hall 4:15 pm - 5:15 pm Plenary Session III Chair: Tim Hughes, University of Toronto

Lecture: Interactome Networks and Human Disease. Marc Vidal.

Lecture Alternative splicing regulatory networks and the control of cell fate. Benjamin Blencowe

5:30 pm - 7:30 pm Poster Session I and Exhibits Hart House, with Canadian Wine and Cheese Tasting University of Toronto 7:30 pm - 8:30 pm Live Entertainment, Amanda and Rasmus Hart House

13th International Conference on Systems Biology August 19 – 23, 2012 Schedule of Events

TUESDAY, August 21 9:00 am - 10:30 am Plenary Session IV Concert Hall Chair: Amy Caudy, University of Toronto

Keynote Lecture and Excellence in Quantitative Education Award; The Princeton Integrated Introductory Science Curriculum. David Botstein.

Lecture: Protein complex-based analysis framework for high- throughput datasets. Norbert Perrimon

Biochemical Approaches to Biomolecular Networks. Anne-Claude Gavin.

10:30 am - 11:00 am Coffee Concert Hall Foyer

11:00 am - 12:40 pm Parallel Sessions The Carlu

Modeling 2 Sky Room Chairs: Roland Eils, DKFZ, Heidelberg; and Per Sunnerhagen, University of Gothenburg Data Analysis and Visualization Round Room Chairs: Quaid Morris, University of Toronto; and Steve Montgomery, Protein Engineering and Protein Interactions Concert Hall Chairs: Tanja Korteme, University of California, San Francisco; Steve Michnick, Universite de Montreal; and Tony Kosiakoff, University of Chicago 12:30 pm - 2:00 pm Lunch Concert Hall Foyer

2:00 pm - 3:25 pm Parallel Sessions The Carlu

Plant Systems Biology Sky Room Chairs: Nick Provart, University of Toronto; and Phil Benfey, Duke University Protein Interaction Networks Concert Hall Chairs: Anne-Claude Gingras, SLRI Toronto; and Igor Stagljar, University of Toronto Genetics Networks 1 Round Room Chairs: Chad Myers, University of Minnesota; and , University of California, San Diego 3:45 pm - 4:15 pm Coffee Concert Hall Foyer

13th International Conference on Systems Biology August 19 – 23, 2012 Schedule of Events

4:00 pm - 5:00 pm Plenary Session V Concert Hall Chair: Igor Stagljar, University of Toronto

Lecture: Regulatory Dynamics in Hormone Signaling and Response Pathways. Joe Ecker.

Lecture: Image-based systems biology at the single-cell level. Lucas Pelkmans.

5:15 pm - 6:30 pm Parallel Sessions The Carlu

RNA Regulatory Systems Concert Hall Chair: Ben Blencowe, University of Toronto Gene Regulatory Networks Round Room Chair: Katsuhiko Shirahige, University of Tokyo Cell Imaging for Systems Biology Sky Room Chair: Yoshi Ohya, University of Tokyo

7:00 pm - 9:00 pm Conference Dinner Evergreen Brickworks 550 Bayview Ave

WEDNESDAY, August 22 9:00 am - 10:30 am Plenary Session VI Concert Hall Chair: Gary Bader, University of Toronto

Keynote Lecture: Adventures in Personal Genomics and Whole Omics Profiling. Michael Snyder.

Lecture Three-Dimensional Structures of Proteins from Genomic Sequencing.

Lecture Evolving high expression. Naama Barkai. 10:30 am - 11:00 am Coffee Concert Hall Foyer

11:00 am - 12:40 pm Parallel Sessions The Carlu

Systems Biology of Host-pathogen interactions Sky Room Chairs: Alex Ensminger, University of Toronto; and Karl Kuchler, University of Vienna Complex Genetic Traits: Modeling and Experimental Design Round Room Chairs: David Gresham, New York University; and Michael Knop, University of Heidelberg, Germany Post-transcriptional Regulatory Networks Concert Hall Chair: Brenda Andrews, University of Toronto 13th International Conference on Systems Biology August 19 – 23, 2012 Schedule of Events

12:30 pm - 2:00 pm Lunch Concert Hall Foyer

The Carlu 2:00 pm - 3:40 pm Parallel Sessions

Genotype to Phenotype Concert Hall Chairs: Anders Blomberg, University of Gothenburg; Barak Cohen, Washington University; and Jens Nielsen, Chalmers University, Sweden Systems Biology of Aging Sky Room Chairs: Thomas Nystrom, University of Gothenburg; and Dan Gottschling, Fred Hutchinson Cancer Research Center Systems Biology of Signal Transduction Round Room Chairs: Mike Tyers, IRIC, Montreal; and Peter Swain, University of Edinburgh Concert Hall Foyer 3:45 pm - 4:15 pm Coffee Concert Hall 4:15 pm - 5:15 pm Plenary Session VII Chair: Jason Moffat, University of Toronto Lecture: Synthetic genetic interaction analysis by high-throughput imaging to map cellular networks. Michael Boutros.

Lecture Haploid Genetic Screens in Human Cells. Thijn R. Brummelkamp Hart House 5:30 pm - 7:30 pm Poster Session II and Exhibits Hart House 6:00 pm - 7:00 pm Beer Tasting and BBQ Pairing Hart House 7:00 pm - 8:00 pm Live Entertainment, Shonen Knife THURSDAY, August 23 9:00 am - 11:00 am Plenary Session VIII Concert Hall Chair: Charlie Boone, University of Toronto

Keynote Lecture Following Single mRNAs from Birth to Death: A Systems Approach. Robert Singer

Lecture The genetics of individuals. Ben Lehner.

Lecture Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells. Jürg Bähler1, Samuel Marguerat1, 2 1 3 4 Alexander Schmidt , Sandra Codlin , Wei Chen , Ruedi Aebersold .