Anti-GNAI3 Monoclonal Antibody, Clone FQS22011 (DCABH-6253) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-GNAI3 monoclonal antibody, clone FQS22011 (DCABH-6253) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to GNAI3

Antigen Description Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GNAI3 aa 300 to the C-terminus (C terminal). The exact sequence is proprietary.Database link: P08754

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS22011

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications Flow Cyt, IHC-P, WB

Positive Control Fetal brain, Fetal kidney, and A431 lysates. Paraffin-embedded Human pancreas tissue, paraffin-embedded Human skeletal muscle tissue.

Format Liquid

Size 100 μl

Buffer pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA, 49% PBS

Preservative 0.01% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

GENE INFORMATION

Gene Name GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [ Homo sapiens ]

Official Symbol GNAI3

Synonyms GNAI3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide-binding protein G(k) subunit alpha; 87U6; g(i) alpha-3; FLJ26559;

Entrez Gene ID 2773

Protein Refseq NP_006487

UniProt ID P08754

Chromosome Location 1p13

Pathway ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Adenylate cyclase inhibitory pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem;

Function G-protein beta/gamma-subunit complex binding; G-protein coupled serotonin receptor binding; GTP binding; GTPase activity; GTPase activity; guanyl nucleotide binding; guanyl-nucleotide exchange factor activity; metal ion binding; nucleotide binding; phosph

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]