M the Battle Against Neglected Tropical Diseases Forging the Chain “Results Innovative Build Trust, and with Intensified Trust, Commitment Management Escalates.”
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SCENES FROM THE BATTLE AGAINST NEGLECTED TROPICAL DISEASES FORGING THE CHAIN “RESULTS INNOVATIVE BUILD TRUST, AND WITH INTENSIFIED TRUST, COMMITMENT MANAGEMENT ESCALATES.” Dr Margaret Chan, WHO Director-General “RESULTS INNOVATIVE BUILD TRUST, AND WITH INTENSIFIED TRUST, COMMITMENT MANAGEMENT ESCALATES.” Dr Margaret Chan, WHO Director-General WHO Library Cataloguing-in-Publication Data Forging the chain: scenes from the battle against neglected tropical diseases, with the support of innovative partners. 1. Tropical Medicine 2. Neglected Diseases I. World Health Organization ISBN 978 92 4 151000 4 (NLM classification: WC 680) © World Health Organization 2016 Acknowledgements All rights reserved. Publications of the World Health Organization are available on the WHO website Forging the chain: scenes from the battle against neglected tropical diseases (with the support of (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, innovative partners) was prepared by the Innovative and Intensified Disease Management (IDM) unit 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). of the WHO Department of Control of Neglected Tropical Diseases under the overall coordination and supervision of Dr Jean Jannin. Requests for permission to reproduce or translate WHO publications – whether for sale or for non-commercial distribution – should be addressed to WHO Press through the WHO website The writing team was coordinated by Deboh Akin-Akintunde and Lise Grout, in collaboration with (www.who.int/about/licensing/copyright_form/en/index.html). Grégoire Rigoulot Michel, Pedro Albajar Viñas, Kingsley Asiedu, Daniel Argaw Dagne, Jose Ramon Franco Minguell, Stéphanie Jourdan, Raquel Mercado, Gerardo Priotto, Prabha Rajamani, Jose The designations employed and the presentation of the material in this publication do not imply the Antonio Ruiz Postigo, Danilo Salvador and Patricia Scarrott. expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation Appreciation is extended to the Ministries of Health, donors, partners, foundations, pharmaceutical of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines companies donating medicines, nongovernmental organizations, research centres, academia and for which there may not yet be full agreement. Maps on page 107 are from Service Commun de colleagues for their generosity and contributions to IDM activities. Lutte contre les grandes endémies. Rapport d'activité depuis sa création (Activity report since its creation). Médecin Général Pierre Richet, octobre 1958 (report prepared from the 12th session of Given the space constraints and the large number of contributors, their names have been omitted the regional committee in Brazzaville). All photographs are from WHO except on pages 18 – 19, 22, but their involvement and commitment are gratefully acknowledged. 30 – 31, 36 – 37, 38, 39, 42, 46 – 47, 68 – 69, 74 and 106 (Patrick Robert) and pages 86, 100 – 101 and 110 (Lâm Duc Hiên). The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the infor- mation contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Art direction and design by Carl Guilhon, Guillaume Peitrequin, Atelier Roger Pfund. Offset printing by Moléson Impressions. Printed in Switzerland. WHO/HTM/NTD/IDM/2016.01 WHO Library Cataloguing-in-Publication Data Forging the chain: scenes from the battle against neglected tropical diseases, with the support of innovative partners. 1. Tropical Medicine 2. Neglected Diseases I. World Health Organization ISBN 978 92 4 151000 4 (NLM classification: WC 680) © World Health Organization 2016 Acknowledgements All rights reserved. Publications of the World Health Organization are available on the WHO website Forging the chain: scenes from the battle against neglected tropical diseases (with the support of (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, innovative partners) was prepared by the Innovative and Intensified Disease Management (IDM) unit 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). of the WHO Department of Control of Neglected Tropical Diseases under the overall coordination and supervision of Dr Jean Jannin. Requests for permission to reproduce or translate WHO publications – whether for sale or for non-commercial distribution – should be addressed to WHO Press through the WHO website The writing team was coordinated by Deboh Akin-Akintunde and Lise Grout, in collaboration with (www.who.int/about/licensing/copyright_form/en/index.html). Grégoire Rigoulot Michel, Pedro Albajar Viñas, Kingsley Asiedu, Daniel Argaw Dagne, Jose Ramon Franco Minguell, Stéphanie Jourdan, Raquel Mercado, Gerardo Priotto, Prabha Rajamani, Jose The designations employed and the presentation of the material in this publication do not imply the Antonio Ruiz Postigo, Danilo Salvador and Patricia Scarrott. expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation Appreciation is extended to the Ministries of Health, donors, partners, foundations, pharmaceutical of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines companies donating medicines, nongovernmental organizations, research centres, academia and for which there may not yet be full agreement. Maps on page 107 are from Service Commun de colleagues for their generosity and contributions to IDM activities. Lutte contre les grandes endémies. Rapport d'activité depuis sa création (Activity report since its creation). Médecin Général Pierre Richet, octobre 1958 (report prepared from the 12th session of Given the space constraints and the large number of contributors, their names have been omitted the regional committee in Brazzaville). All photographs are from WHO except on pages 18 – 19, 22, but their involvement and commitment are gratefully acknowledged. 30 – 31, 36 – 37, 38, 39, 42, 46 – 47, 68 – 69, 74 and 106 (Patrick Robert) and pages 86, 100 – 101 and 110 (Lâm Duc Hiên). The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the infor- mation contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Art direction and design by Carl Guilhon, Guillaume Peitrequin, Atelier Roger Pfund. Offset printing by Moléson Impressions. Printed in Switzerland. WHO/HTM/NTD/IDM/2016.01 ABBREVIATIONS 7 CIRDES DNDI ↓ ↓ CENTRE DRUGS FOR INTERNATIONAL NEGLECTED DE RECHERCHE- DISEASES INITIATIVE DÉVELOPPEMENT SUR L’ELEVAGE FAO EN ZONES ↓ SUBHUMIDES FOOD AND AGRICULTURE DDT ORGANIZATION ↓ OF THE UNITED DICHLORODIPHENYL- NATIONS TRICHLOROETHANE GPS DNA ↓ ↓ GLOBAL DEOXYRIBONUCLEIC POSITIONING ACID SYSTEM ABBREVIATIONS 7 CIRDES DNDI ↓ ↓ CENTRE DRUGS FOR INTERNATIONAL NEGLECTED DE RECHERCHE- DISEASES INITIATIVE DÉVELOPPEMENT SUR L’ELEVAGE FAO EN ZONES ↓ SUBHUMIDES FOOD AND AGRICULTURE DDT ORGANIZATION ↓ OF THE UNITED DICHLORODIPHENYL- NATIONS TRICHLOROETHANE GPS DNA ↓ ↓ GLOBAL DEOXYRIBONUCLEIC POSITIONING ACID SYSTEM 8 HAT NGO 9 ↓ ↓ HUMAN AFRICAN ITM NONGOVERNMENTAL TRYPANOSOMIASIS ↓ ORGANIZATION INSTITUTE OF SSNCP HIV/AIDS TROPICAL MEDICINE NTD ↓ ↓ ↓ SLEEPING SICKNESS HUMAN MSF NEGLECTED NATIONAL IMMUNODEFICIENCY ↓ TROPICAL CONTROL VIRUS/ACQUIRED MÉDECINS SANS DISEASE PROGRAMME IMMUNODEFICIENCY FRONTIÈRES SYNDROME PCR WHA NECI ↓ ↓ IDM ↓ POLYMERASE WORLD HEALTH ↓ NON-ENDEMIC CHAIN REACTION ASSEMBLY INNOVATIVE AND COUNTRIES INTENSIFIED INITIATIVE PPV WHO DISEASE ↓ ↓ MANAGEMENT NECT POSITIVE WORLD HEALTH ↓ PREDICTIVE VALUE ORGANIZATION IRD NIFURTIMOX- ↓ EFLORNITHINE STI INSTITUT DE COMBINATION ↓ RECHERCHE THERAPY SWISS TROPICAL POUR LE INSTITUTE DÉVELOPPEMENT 8 HAT NGO 9 ↓ ↓ HUMAN AFRICAN ITM NONGOVERNMENTAL TRYPANOSOMIASIS ↓ ORGANIZATION INSTITUTE OF SSNCP HIV/AIDS TROPICAL MEDICINE NTD ↓ ↓ ↓ SLEEPING SICKNESS HUMAN MSF NEGLECTED NATIONAL IMMUNODEFICIENCY ↓ TROPICAL CONTROL VIRUS/ACQUIRED MÉDECINS SANS DISEASE PROGRAMME IMMUNODEFICIENCY FRONTIÈRES SYNDROME PCR WHA NECI ↓ ↓ IDM ↓ POLYMERASE WORLD