Canine Brucellosis Brucella Canis

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Canine Brucellosis Brucella canis What is canine brucellosis Can I get canine brucellosis? Who should I contact, if I and what causes it? Yes. However, human infections suspect canine brucellosis? Canine brucellosis is an important with Brucella canis are rare. Direct In Dogs – Contact your cause of reproductive failure in contact or aerosol exposure to veterinarian immediately. dogs, particularly in kennels. Canine infected animal fluids is the primary In Humans – Contact your brucellosis is caused by the bacteria way people are infected with canine physician immediately Brucella (bru-CELL-a) canis. Dogs brucellosis. People can also become How can I protect my and humans can be affected. Canine infected by ingesting the bacteria brucellois occurs in a number of or by contamination of mucous animals from canine countries worldwide. membranes and breaks in the skin. brucellosis? Infection with Brucella canis Brucella canis can survive for What animals get canine seems to require close contact months in the environment under brucellosis? with infected dogs or contact with optimum conditions but can Dogs are the primary animal bacterial cultures. People who work be destroyed by heat and some species that can be infected with with dogs in a breeding situation disinfectants. Thoroughly clean and Brucella canis. However, other animals (e.g., breeders, kennel workers, disinfect areas exposed to infected can be infected experimentally. veterinarians) may be at higher dogs, their urine, blood, milk, or risk of exposure. discharges. Keep sick dogs away from How can my dog get canine other dogs to avoid spreading the Infection in people causes flu-like brucellosis? disease. Carefully screen dogs that signs (fever, night sweats, headaches, In dogs, brucellosis is usually are being introduced into a breeding back pain). Arthritis (joint pain) spread through contact with program to control transmission. and re-occurring fevers may occur infected birthing tissues and fluids with long term infection. Rarely, (e.g., placenta, aborted fetuses, fetal How can I protect myself cases of brucellosis can involve fluids, vaginal discharges). Canine from canine brucellosis? the nervous system, eyes, or heart. brucellosis can also be transmitted by Wear protective clothing (gloves, contaminated objects (fomites) such masks) when handling reproductive as, bedding, equipment, clothing, tissues (assisting delivery of newborn or shoes, . The bacteria can also be puppies). Always wash your hands found in the milk, blood, and semen after touching animals. of infected dogs. For More Information Entry of the bacteria can occur by ingestion or direct contact with CFSPH Technical Fact Sheets. Brucella mucous membranes (eyes, nose, canis at http://www.cfsph.iastate.edu/ DiseaseInfo/ mouth), or breaks in the skin. CDC website. Brucellosis at http://www. How does canine cdc.gov/ncidod/dbmd/diseaseinfo/ brucellosis_g.htm brucellosis affect my dog? Canine Brucellosis Brucella canis causes reproductive is an important cause problems (e.g. abortions, stillbirth, of reproductive failure infertility) in dogs. Other signs can in dogs. include inflammation of lymph nodes, behavioral abnormalities, lethargy, Photo from Claudia Baldwin, Iowa State and weight loss. University, College of Veterinary Medicine © 2013.

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Brucella Canis and Public Health Risk İsfendiyar Darbaz , Osman Ergene
DOI: 10.5152/cjms.2019.694 Review Brucella canis and Public Health Risk İsfendiyar Darbaz , Osman Ergene Department of Obstetrics and Gynaecology, Near East University School of Veterinary Medicine, Nicosia, Cyprus ORCID IDs of the authors: İ.D. 0000-0001-5141-8165; O.E. 0000-0002-7607-4044. Cite this article as: Darbaz İ, Ergene O. Brucella Canis and Public Health Risk. Cyprus J Med Sci 2019; 4(1): 52-6. Pregnancy losses in dogs are associated with many types of bacteria. Brucella canis is reported to be one of the most important bacterial species causing pregnancy loss in dogs. Dogs can be infected by 4 out of 6 Brucella species (B. canis, B. abortus, B. melitensis, and B. suis). B. canis is a Gram- negative coccobacillus first isolated by Leland Carmichael and is a cause of infertility in both genders. It causes late abortions in female dogs and epididymitis in male dogs. Generalized lymphadenitis, discospondylitis, and uveitis are shown as the other major symptoms. B. canis infections can easily be formed as a result of the contamination of the oronasal, conjunctival, or vaginal mucosa . Infection can affect all dog breeds and people. While morbidity may be high in infection, mortality has been reported to be low. Most dogs are asymptomatic during infection, and it is difficult to convince their owners that their dogs are sick and should not be used in reproduction. The diagnosis of the disease is quite complex. Serological tests may provide false results or negative results in chronic cases. Therefore, diagnosis should be defined by combining the results of serological studies and bacterial studies to provide the most accurate result.
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Canid, Hye A, Aardwolf Conservation Assessment and Management Plan (Camp) Canid, Hyena, & Aardwolf
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S L I D E 1 Canine Brucellosis, Caused by Brucella Canis, Is an Important Cause of Reproductive Failure, Particularly in Kennels
Canine Brucellosis: Brucella canis S Canine brucellosis, caused by Brucella canis, is an important cause of l reproductive failure, particularly in kennels. B. abortus causes abortions, i stillbirths, epididymitis, orchitis and sperm abnormalities in dogs. Canine d Canine Brucellosis: brucellosis can end the reproductive career of a breeding animal. B. canis e Brucella canis is zoonotic, although disease appears to be rare in humans. Contagious Abortion, 1 Undulant Fever S In today’s presentation we will cover information regarding the organism l Overview that causes canine brucellosis and its epidemiology. We will also talk • Organism about the history of the disease, how it is transmitted, species that it i • History d • Epidemiology affects (including humans), and clinical and necropsy signs observed. e • Transmission Finally, we will address prevention and control measures for canine • Disease in Humans brucellosis, as well as actions to take if canine brucellosis is suspected. • Disease in Animals 2 • Prevention and Control [Photo: Dog and pup. Source: AVMA Photo Gallery] • Actions to Take Center for Food Security and Public Health, Iowa State University, 2012 S l i d e THE ORGANISM 3 S In dogs, brucellosis is mainly caused by Brucella canis, a Gram-negative l The Organism coccobacillus or short rod. This organism is a facultative intracellular i • Brucella canis pathogen. Other Brucella species occasionally associated with disease in – Gram negative dogs include Brucella abortus, B. melitensis and B. suis. Genetic and d coccobacillus e – Facultative immunologic evidence suggests that all members of the genus Brucella intracellular pathogen are closely related, and some microbiologists have proposed that this • Other Brucella species genus be reclassified into a single species (B.
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Redalyc.Identification of Brucella Canis Group 2 in Colombian Kennels
Revista Colombiana de Ciencias Pecuarias ISSN: 0120-0690 [email protected] Universidad de Antioquia Colombia Ortiz, Luisa F; Muskus, Carlos; Sánchez, Miryan M; Olivera, Martha Identification of Brucella canis Group 2 in colombian kennels Revista Colombiana de Ciencias Pecuarias, vol. 25, núm. 4, 2012, pp. 615-619 Universidad de Antioquia Medellín, Colombia Available in: http://www.redalyc.org/articulo.oa?id=295024922009 How to cite Complete issue Scientific Information System More information about this article Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Journal's homepage in redalyc.org Non-profit academic project, developed under the open access initiative Ortíz et al. Brucella canis in colombian kennels 615 Revista Colombiana de Ciencias Pecuarias Identification ofBrucella canis Group 2 in colombian kennels¤ Identificación de Brucella canis Grupo 2 en criaderos de perros en Colombia Identificação de Brucella canis Grupo 2 em criadouros de cães na Colômbia Luisa F Ortiz1, MyB; Carlos Muskus2, Bact, PhD; Miryan M Sánchez3, Bact, Ms; Martha Olivera3*, MV, PhD. 1 Universidad de Antioquia, Facultad de Ciencias Agrarias, Grupo Biogénesis. Carrera 75 # 65-87, Medellín, Colombia. 2 Universidad de Antioquia, Programa de Estudio y Control de Enfermedades Tropicales (PECET), Sede de Investigación Universitaria (SIU). Calle 62 # 52-59, Lab. 632. Medellín, Colombia. 3 Universidad de Antioquia, Facultad de Ciencias Agrarias, Grupo Vericel. Carrera 75 # 65-87. Medellín, Colombia. (Received: 1 december, 2011; accepted: 1 august , 2012) Summary Background: recently, isolates of Brucella canis (B. canis) were classified into two groups, Group 1 and Group 2, based on a 794 bp deletion in the polysaccharide deacetylase gene in Group 1, or absence of this deletion in Group 2.
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Canine Brucellosis and Human Health Questions and Answers for Veterinarians
Wisconsin Department of Health Services P- 00614A (Rev 1/14) Division of Public Health Page 1 of 2 Canine Brucellosis and Human Health Questions and Answers for Veterinarians • WHY IS CANINE BRUCELLOSIS IMPORTANT FROM A PUBLIC HEALTH PERSPECTIVE? Canine brucellosis, caused by Brucella canis, is a significant cause of reproductive failure in dogs, but it is also a zoonotic disease. Veterinarians are urged to educate their staff and their clients, particularly those who own breeding kennels, about this disease and its potential to cause illness in humans. In Wisconsin, canine brucellosis is reportable to the Office of the State Veterinarian. • HOW IS CANINE BRUCELLOSIS TRANSMITTED? 1. Dog to Dog: In infected dogs, B. canis is predominately present in the placenta, the fetus and fetal fluids, vaginal discharge and secretions, semen, milk, urine, feces, saliva, and nasal and ocular secretions. Most dog-to-dog transmission occurs by oronasal contact with vaginal discharge of an infected female during estrus, breeding, abortion, or whelping. Transmission occurs through contact with oral, nasal, conjunctival, and genital mucous membranes, abrasions in the skin, and via placenta. It is also commonly transmitted through semen or urine, and can be shed by intact or castrated males for several years in cases of chronic infection. 2. Dog to Human: Dogs are the only natural reservoir of B. canis. The most common way humans become infected is through contact with birthing fluids, canine abortion products, or vaginal discharges from an infected dog. Brucella canis can be transmitted if these infectious materials contact a person’s mucous membranes or abraded skin.
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Canine Brucellosis Questions and Answers for Dog Owners
Wisconsin Department of Health Services P- 00614 (Rev 1/14) Division of Public Health Page 1 of 2 Canine Brucellosis Questions and Answers for Dog Owners • WHAT IS CANINE BRUCELLOSIS? Canine brucellosis is an infectious disease caused by the Brucella canis (B. canis) bacterium. Although other Brucella species can infect dogs, such as Brucella suis (pigs) and Brucella abortus (cattle), B. canis is the most common Brucella species found in dogs and will be the only bacterium discussed here. • WHY IS CANINE BRUCELLOSIS IMPORTANT FROM A PUBLIC HEALTH PERSPECTIVE? B. canis is a bacterium that can be transmitted to humans as well as other dogs and is a significant cause of reproductive failure in canines. • WHAT ARE THE SIGNS OF BRUCELLOSIS IN DOGS? In female dogs, brucellosis usually causes abortion between the 45th and 59th day of pregnancy. Other common reproductive symptoms include failure to conceive in an otherwise healthy dog, infertile males with abnormal semen quality and enlarged testicles that subsequently decrease in size. Non-specific symptoms for both sexes include: lethargy (decrease in activity, depressed), loss of libido, premature aging, and generalized lymph node enlargement. Pups infected prior to whelping may be born weak or appear normal and later develop brucellosis. • HOW DO DOGS GET INFECTED WITH CANINE BRUCELLOSIS? Canine brucellosis is mainly transmitted during breeding. The most common mechanism of dog-to-dog transmission is by nose and mouth contact with vaginal discharge from an infected female. This can occur while the female is in heat, after an abortion, or during whelping. Brucellosis may also be transmitted through semen or urine and can be shed by intact or neutered males for several years in cases of chronic infection.
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Convergent Evolution of Zoonotic Brucella Species Toward the Selective Use of the Pentose Phosphate Pathway
Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway Arnaud Machelarta,b,1, Kevin Willemarta,1, Amaia Zúñiga-Ripac, Thibault Godardd, Hubert Ploviere, Christoph Wittmannf, Ignacio Moriyónc, Xavier De Bollea,2, Emile Van Schaftingeng,h, Jean-Jacques Letessona,3, and Thibault Barbiera,i,2,3 aResearch Unit in Biology of Microorganisms, Narilis, University of Namur, B-5000 Namur, Belgium; bCenter for Infection and Immunity of Lille, Université de Lille, CNRS, INSERM, Centre Hospitalier Universitaire de Lille, Institut Pasteur de Lille, U1019, Unité Mixtes de Recherche 9017, 59000 Lille, France; cDepartamento de Microbiología e Instituto de Salud Tropical, Instituto de Investigación Sanitaria de Navarra, Universidad de Navarra, 31009 Pamplona, Spain; dInstitute of Biochemical Engineering, Technische Universität Braunschweig, 38106 Braunschweig, Germany; eMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and Biotechnology (WELBIO), Université Catholique de Louvain (UCLouvain), 1200 Brussels, Belgium; fInstitute of Systems Biotechnology, Universität des Saarlandes, 66123 Saarbrücken, Germany; gDe Duve Institute, UCLouvain, 1200 Brussels, Belgium; hWELBIO, UCLouvain, 1200 Brussels, Belgium; and iDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115 Edited by Roy Curtiss III, University of Florida, Gainesville, FL, and approved August 25, 2020 (received for review May 5, 2020) Mechanistic understanding of the factors that govern host tropism network should similar in all Brucella species (7) and other Rhi- remains incompletely understood for most pathogens. Brucella zobiales (8, 9). It includes all enzymes of the pentose phosphate species, which are capable of infecting a wide range of hosts, offer pathway (PPP), Entner–Doudoroff pathway (EDP), Krebs cycle a useful avenue to address this question.
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Highly Sensitive Bacteriophage-Based Detection of Brucella Abortus in Mixed Culture and Spiked Blood
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Best Practices for Brucella Canis Prevention And
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Brucellosis: Brucella Suis
Brucellosis: Importance Brucellosis is a zoonotic bacterial disease caused by several species in the genus Brucella suis Brucella. Reproductive losses are the most common syndrome in animals, while humans may suffer from a debilitating nonspecific illness or localized involvement of Porcine Brucellosis, various organs. Each organism tends to be associated with a specific animal host, but Rangiferine Brucellosis, other species can be infected, especially when they are kept in close contact. Domesticated and/or wild pigs are the usual hosts for biovars 1, 2 and 3 of Brucella Enzootic Abortion, suis. Biovar 4 circulates in caribou and reindeer in Arctic regions, while biovar 5 has Contagious Abortion, been reported only in wild rodents. Most people become infected by direct contact Undulant Fever, with infected animals or their tissues, or by the ingestion of contaminated animal products. B. suis is common in domesticated pigs in some parts of the world, such as Asia Last Updated: May 2018 and Latin America. This organism has been virtually eradicated from commercial herds in some other regions; however, it is still maintained in wild or feral swine in many of these areas, including North America and Europe. This complicates brucellosis control, especially for domesticated pigs kept outdoors. In addition, clinical cases are sometimes reported in hunting dogs and people who hunt wild pigs. Occasionally, organisms from wild suids infect other livestock such as cattle, resulting in additional risks to human health. B. suis has also been weaponized, and there are concerns that it could be used in a bioterrorist attack. Etiology Brucella suis is a Gram negative coccobacillus in the family Brucellaceae (class Alphaproteobacteria) Five biovars with different host preferences are currently recognized.
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