12Th Annual Q-Bio Conference June 26 - 29, 2018
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12th Annual q-bio Conference June 26 - 29, 2018 BioScience Research Collaborative (BRC) Rice University Houston, TX 12th Annual q-bio Conference JUNE 26 - 29, 2018 BioScience Research Collaborative (BRC) Rice University, Houston, TX PROGRAM Unless otherwise noted, all talks are held in the BRC Auditorium (Room 103) TUESDAY, JUNE 26 12:00 - 4:00 PM - CONFERENCE ATTENDEE CHECK-IN BRC LOBBY – AUDITORUM 103 (PRE-FUNCTION SPACE) 1:00 - 3:30 PM - TUTORIALS/PARALLEL SESSIONS 1:00 – 3:30 PM “Introduction to Rule-Based Modeling with BRC 282 BioNetGen” 1:00 – 3:30 PM “Tutorial on StochSS: An Integrated Development BRC 284 Environment for Simulation and Analysis of Discrete Stochastic Biochemical Models” 4:00 - 4:30 PM Opening Remarks 4:30 - 5:30 PM Keynote Talk: “Thinking About the Cancer- Herbert Levine, Rice University Immune Interaction” 6:30 - 10:00 PM Night at the Museum Reception Houston Museum of Natural Science WEDNESDAY, JUNE 27 SESSION I Session Chair: Fred Mackintosh, Rice University 9:00 - 9:30 AM Invited Talk: “Quantitative Behavior: Joshua Shaevitz, Princeton Understanding What Animals Do and How Brains University Control Them” 9:30 - 9:50 AM Contributed Talk: “Sign Epistasis Induced by Arvind Subramaniam, Fred Ribosome Collisions During Eukaryotic mRNA Hutchinson Research Center Translation” 9:50 - 10:10 AM Contributed Talk: “Properties of Gene Expression Stuart Sevier, Rice University and Chromatin Structure with Mechanically Regulated Transcription” 10:10 - 10:30 AM Contributed Talk: “Phase Transitions and Critical Bo Wang, Stanford University Phenomena in Mutualistic Communities under Invasion” 10:30 - 11:00 AM - COFFEE BREAK Program continued… 1 12th Annual q-bio Conference PROGRAM, continued… SESSION II Session Chair: Oleg Igoshin, Rice University 11:00 - 11:30 am Invited Talk: “Evolutionary Search and Races in Shenshen Wang, University of the Adaptive Immune System” California, Los Angeles 11:30 – 11:50 am Contributed Talk: “Precision in a Rush: Huy Tran, École Normale Supérieur Hunchback Pattern Formation in a Limited Time” 11:50 - 12:20 AM - Spotlight Talk Session I “Anomalous Diffusion, Spatial Coherence, and Michelle Di Pierro, Rice University Viscoelasticity from the Epigenetic Energy Landscape of Human Chromosomes” “Quantifying Epistatic Conservation Across Genetic Andrew D. Mathis, University of and Environmental Backgrounds” Texas Southwestern Medical Center “Modeling the Regulation of Cancer Metabolism: Dongya Jia, Rice University Interplay Between Glycolysis and OXPHOS” “Antigen Recognition at Immune-Cell Interfaces: Steven M. Abel, University of Probing the Role of Mechanical Forces” Tennessee, Knoxville “Agent-Based Model for Developmental Zhaoyang Zhang, Rice University Aggregation in Myxococcus xanthus Bacteria” “Effects of Cell Cycle Noise on Excitable Circuits” William Ott, University of Houston 12:20 - 1:30 PM – LUNCH BioScience Research Collaborative, Event/Exhibition Hall, Room 120 12:20 – 1:30 PM Special Session: “NIH Peer Review and Research Craig, N Giroux, Center for Initiatives for Quantitative Biologists” Scientific Review/NIH (10th Floor, BRC Room 1060 A/B) SESSION III Session Chair: Ido Golding, Baylor College of Medicine 1:30 - 2:00 PM Invited Talk: “Hyaluronan Glycocalyx Physically Jennifer Curtis, Georgia Institute of Modulates Cell Adhesion and Migration” Technology 2:00 - 2:30 PM Invited Talk: "Comprehensive, High-Resolution Polly Fordyce, Stanford University Binding Energy Landscapes of Transcription Factor Binding" Program continued… 2 12th Annual q-bio Conference PROGRAM, continued… 2:30 - 3:00 PM - SPOTLIGHT TALK SESSION II “Using the Automated Building of Computational Robert P. Sheehan, Harvard Models to Understand Cardiotoxic Drug Responses” Medical School “Modulation of Conjugation in Pathogenic Jonathan Bethke, Duke University Escherichia coli” “The Role of Metabolic Spatiotemporal Dynamics in Federico Bocci, Rice University Modulating Biofilm Colony Expansion” “Spatiotemporal Dynamics of Phage-Biofilm Hemaa Selvakumar, Georgia Interactions” Institute of Technology “Ensemble response of immune repertoires to Maximilian Puelma Touzel, École Vaccination” Normale Supérieur “Modularity of the Metabolic Gene Network as a Fengdan Ye, Rice University Prognostic Biomaker for Hepatocellular Carcinoma” 3:00 - 3:30 PM - COFFEE BREAK SESSION IV Session Chair: Joshua Shaevitz, Princeton University 3:30 - 3:50 PM Contributed Talk: “An Artificial Cell-Cycle Qiong Yang, University of Michigan System: How Network Structures Modulate the Clock Functions” 3:50 - 4:10 PM Contributed Talk: “How to Model Cell Decision Ali Abdi, New Jersey Institute of Making Errors” Technology 4:10 - 4:30 PM Contributed Talk: “Design principles of Binding- Loren Hough, University of Induced Selective Transport Through the nuclear Colorado, Boulder Pore Complex” 4:30 - 4:50 PM Contributed Talk: “Increased Mortality Favors Clare Abreu, Massachusetts Fast-Growing Species in Microbial Communities” Institute of Technology, Gore Lab 4:50 - 5:10 PM Contributed Talk: “Synthetic NF-κB: A Building Ping Wei, Center for Quantitative Approach to Study Complex Signaling Behaviors” Biology, Peking University 7:30 – 10:00 PM - POSTER SESSION BioScience Research Collaborative, Event/Exhibition Hall, Room 120 THURSDAY, JUNE 28 SESSION V Session Chair: Linchong You, Duke University 9:00 - 9:30 AM Invited Talk: “The Outer Membrane is an Essential KC Huang, Stanford University Load-Bearing Element in Gram-Negative Bacteria” 9:30 -10:00 AM Invited Talk: “Ant Rafts and Maggot Flows” David Hu, Georgia Institute of Technology Program continued… 3 12th Annual q-bio Conference PROGRAM, continued… 10:00 - 10:30 AM - SPOTLIGHT TALK SESSION III “Dynamic Interrogation of the Bacillus Subtilis Sebastian Castillo-Hair, Rice Sporulation Network using an Engineered Light- University Switchable Two-Component System” “Temporal Precision of Regulated Gene Expression” Shivam Gupta, Purdue University “Carbohydrate Storage Determines Cell Size and Yanjie Liu, University of Texas Cell Fate” Southwestern Medical Center “Survival of the Chiral” Ashish Bino George, Boston University “Causes and Consequences of Asynchrony in D. Ricardo Martinez-Garcia, Princeton discoideum Multicellular Development” University “Measuring Transcription from a Single Gene Copy Jing Zhang, Baylor College of in Live Escherichia coli Cells” Medicine 10:30 - 11:00 AM - COFFEE BREAK SESSION VI Session Chair: Yi Jiang, Georgia State University 11:00 - 11:30 AM Invited Talk: “Regulatory Networks in Synthetic Matthew Bennett, Rice University Microbial Consortia” 11:30 - 11:50 AM Contributed Talk: “Impact of a Periodic Presence Anne-Florence Bitbol, Institut Curie of Antimicrobial on Resistance Evolution” 11:50 - 12:10 PM Contributed Talk: “A High Throughput Coralie Dessauges, University of Optogenetic System to Interrogate MAPK Signaling Bern Network Dynamics at the Single Cell Level” 12:10 - 12:30 PM Contributed Talk: “In-Sequence Coding of Noise Enrique Balleza, Harvard in Gene Expression” University 12:30 – 1:45 PM - LUNCH BioScience Research Collaborative, Event/Exhibition Hall, Room 120 SESSION VII Session Chair: Elena Koslover, University of California, San Diego 1:45 - 2:15 PM Invited Talk: “The Microbial Brain: Gurol Suel, University of California, Electrochemical Signaling and Higher-Order San Diego Coordination in Bacterial Communities” 2:15 - 2:45 PM Invited Talk: “When Things Go Wrong: A Eleni Katifori, University of Breakdown of Breakdowns in Optimally Resilient Pennsylvania Vascular Networks” Program continued… 4 12th Annual q-bio Conference PROGRAM, continued… 2:45 - 3:15 PM - SPOTLIGHT TALK SESSION IV “Multiplexing Cell-Cell Communication” John Sexton, Rice University “Role of Stochasticity in Mammalian Drug Kevin Farquhar, Laufer Center for Resistance” Physical and Quantitative Biology “Regulation of T Cell Expansion by the Dynamics Andreas Mayer, Lewis-Sigler of Antigen Presentation” Institute, Princeton University “Stochastic Modeling Quantifies Tumor Elimination Jason George, Rice University and Evasion in the Setting of Immunotherapy” “Optimal Sensory Network for the Unfolded Protein Wylie Stroberg, University of Response” Michigan “Intracellular Bistable Signaling in Streptococcus Simon Underhill, University of mutans Competence Regulation” Florida 3:15 – 3:45 PM - COFFEE BREAK SESSION VIII Session Chair: Michael Diehl, Rice University 3:45 - 4:05 PM Contributed Talk: “Metabolic Organization Elena Koslover, University of Through Glucose-Mediated Regulation of California, San Diego Mitochondrial Transport” 4:05 - 4:35 pm Invited Talk: “Membrane Criticality and Ion Ben Machta, Yale University Channel Function” 4:35 - 4:55 PM Contributed Talk: “Emergent Versus Individual- Sean Fancher, Purdue University Based Multicellular Chemotaxis” 4:55 -5:15 PM Contributed Talk: “Evolution of New Regulatory Tamar Friedlander, Hebrew Functions” University of Jerusalem 7:30 – 10:00 PM - POSTER SESSION BioScience Research Collaborative, Event/Exhibition Hall, Room 120 FRIDAY, JUNE 29 SESSION IX Session Chair: Dmitry Makarov, University of Texas 9:00 - 9:30 am Invited Talk: “Binary Transcriptional Control of Hernan Garcia, University of Pattern Formation in Development” California, Berkeley 9:30 -10:00 am Invited Talk: “Crowd Dynamics on a Lively Igor Belykh, Georgia State Bridge” University 10:00 - 10:20 am Contributed Talk: “In situ Analysis of Microbial Youngbin Lim, Stanford University Communities Using Expansion Microscopy” 10:20 -10:40 am Contributed Talk: “Homeostasis