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ASID New Zealand 020 Annual Meeting ASID New Zealand 2020 Annual Meeting CONFERENCE HANDBOOK E: [email protected] W: www.asid.net.au/groups/nz-annual-meeting ASID New Zealand 2020 Annual Meeting 0 ASID New Zealand 2020 Annual Meeting Friday 30 October 2020 9:00 am to 4:30 pm (NZDT) Convener: Dr Chris Hopkins ASID Secretariat: Marilena Salvo, Senior Executive Officer Maureen Ryan, Events Manager This year's event will be held as a virtual meeting with hubs in the following locations: • Auckland (main hub): Parnell Community Centre, Pukekawa & Bledisloe Rooms, Jubilee Building, 545 Parnell Road, Parnell • Auckland: North Shore Hospital Hospice Seminar Room 1, level 3 • Christchurch: Manawa Building Room HP303 - 276 Antigua Street, Christchurch Central, Christchurch • Midlands: Tauranga Hospital, Ako Room, Pathlab Bay of Plenty, Cameron Road, Tauranga • Wellington: Wellington Hospital, Level 6, Grace Neill Block Image: Hub locations Twitter hashtag: Join the conversation at #asidnz20 The program is current at the time of publishing and is subject to change at short notice. The Australasian Society for Infectious Diseases is the peak professional body for infectious diseases and microbiology in the region and a key stakeholder for government departments, medical colleges and other societies, including international organisations. ASID New Zealand 2020 Annual Meeting 1 Invited Speakers Professor/Ahorangi Michael Baker Department of Public Health/Te Tari Hauora Tūmatanui; University of Otago, Wellington/Te Whare Wānanga o Otāgo ki Te Whanga-nui-a-Ta Michael Baker is a public health physician and Professor in the Department of Public Health at the University of Otago. He is a member of the Ministry of Health’s COVID-19 Technical Advisory Group, has taken a leading role in formulating New Zealand’s elimination strategy against this pandemic and established a programme of research on the epidemiology, prevention and control of COVID-19 with support from the Health Research Council of New Zealand. Dr Ashley Bloomfield Director-General of Health and Chief Executive Dr Bloomfield qualified in medicine at the University of Auckland in 1990 and after several years of clinical work specialised in public health medicine. His particular area of professional interest is non-communicable disease prevention and control, and he spent 2011 at the World Health Organization in Geneva working on this topic at a global level. Dr Bloomfield was Chief Executive at Hutt Valley District Health Board from 2015 to 2018. Prior to that, he held a number of senior leadership roles within the Ministry of Health. Dr Richard Chen Urgent Care Physician prior to COVID-19. Quarantine Medical Lead since February 2020. Involved with initial operations at the Whangaparaoa Naval Base for Evacuees out of the Wuhan Epicenter and later Guests from the Diamond Princess Cruise Ship Outbreak. Now stationed at Jet Park Quarantine responsible for COVID-19 cases from across the border and community clusters within the Greater Auckland, Waikato and Rotorua Regions. ASID New Zealand 2020 Annual Meeting 2 Invited Speakers Professor Allen Cheng Allen Cheng is Director of the Infection Prevention and Healthcare Epidemiology Unit at Alfred Health, and Professor of Infectious Diseases Epidemiology at the School of Public Health and Preventive Medicine at Monash University. He is the current ASID President, Co-Chair of the Australian Technical Advisory Group on Immunisation and a member of several other government advisory committees. Dr Gary McAuliffe Dr McAuliffe is a graduate of Imperial College School of Medicine in the UK. He trained in microbiology in Christchurch, Auckland, and Darwin. Relevant areas of clinical experience include: paediatrics, adult infections and tropical medicine. In addition to being Medical Director of Labtests and Northland Pathology Laboratory, Dr McAuliffe works eight tenths at Labtests as a clinical microbiologist, and two tenths in the microbiology department at LabPLUS, Auckland Hospital. Dr McAuliffe is a Fellow of the Royal College of Pathologists of Australasia. Dr Mariam Parwaiz Public Health Medicine Specialist Dr Parwaiz is a public health medicine specialist and, since July 2020, has been the clinical lead for the ARPHS COVID-19 response. Dr Parwaiz completed her medical degree at the University of Otago in 2012 and recently completed public health medicine specialist training. In addition to previous roles at ARPHS, Dr Parwaiz has worked in public health positions at Counties Manukau Health and Te Marae Ora Cook Islands Ministry of Health, and has served on the Council of the New Zealand College of Public Health Medicine as the Registrar Representative. ASID New Zealand 2020 Annual Meeting 3 The 2020 ASID NZ Annual Meeting is made possible with the generous support of our sponsors More information on the sponsors can be found from page 19. ASID New Zealand 2020 Annual Meeting 4 ASID New Zealand 2020 Annual Meeting Program Friday 30 October, online streaming with regional hubs TIME SPEAKER SITE TITLE 8:30 REGISTRATION / SOUND CHECK 9:00 Chris Hopkins Auckland hub Welcome 9:05 Tim Cutfield & Amanda Taylor London COVID-19 in London 9:20 Gary McAuliffe Auckland hub Laboratory response to COVID-19 9:40 Michael Baker Christchurch hub The COVID-19 elimination strategy: Implications and opportunities for NZ 10:00 Ashley Bloomfield Auckland hub Ministry of Health response to COVID-19 10:20 Mariam Parwaiz Auckland hub The August Auckland outbreak 10:40 Panel kōrero 11:00 PAKARU KAWHE / COFFEE BREAK 11:20 Allen Cheng Melbourne Victoria's second wave - lessons learned 11:40 Shivani Fox-Lewis Auckland hub A comparison of SARS-CoV-2 antibody assays evaluated in Auckland, New Zealand 12:00 Susan Morpeth Auckland hub COVID-19 clinical trials in NZ 12:20 Richard Chen Auckland hub Being the quarantine doctor SARS-CoV-2 viral load dynamics & real-time RT-PCR cycle threshold interpretation in symptomatic non- 12:35 Andrew Fox-Lewis Auckland hub hospitalised individuals in NZ 12:50 Nadia Mekki Perth Healthcare Workers’ Perceptions on the COVID-19 Pandemic in a Western Australian Hospital 13:05 TINA / LUNCH 13:20 AGM Highly effective prophylaxis with ertapenem for transrectal ultrasound-guided prostate biopsy: effects on 14:15 Max Bloomfield Wellington hub overall antibiotic use and inpatient hospital exposure Ceftazidime-avibactam plus aztreonam susceptibility testing against New Zealand metallo-beta- 14:30 Aaron Keene Tauranga hub lactamase producing Enterobacterales 14:45 Leeyan Gilmour Auckland hub The Alarming Reality: Our New Zealand Congenital Syphilis Epidemic 15:00 PAKARU KAWHE / COFFEE BREAK 15:30 Aaron Keene & Kevin Chen Tauranga hub A cluster of botulism cases in the Bay of Plenty. Clinical presentation, treatment, diagnostics and pitfalls. 15:45 Katie Walland Auckland hub Do patients with sepsis die of sepsis? A narrative review 16:00 Simon Briggs Auckland hub Enterococcal endocarditis treatment with benzylpenicillin plus ceftriaxone A Qualitative Study Investigating Emergency Department Nurse and Doctor Perceptions of Sepsis 16:15 Alice Rogan Wellington hub Management & Factors Impacting on Patient Care 16:30 CLOSE ASID New Zealand 2020 Annual Meeting 5 Proffered Papers Abstracts A comparison of SARS-CoV-2 antibody assays evaluated in Auckland, New Zealand Authors: Fox-Lewis S1, Whitcombe A2,3, McGregor R2,3, Carlton L2, Hwang Y1, Austin P1, Aspin L4, Raill B5, Webb R2,6,7, Taylor S8, Morpeth S8, Roberts S3,9, Moreland NJ2,3, McAuliffe G1,10 1Department of Virology-Immunology, LabPLUS, Auckland City Hospital, Auckland, New Zealand 2Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand 3Maurice Wilkins Centre, University of Auckland, Auckland, New Zealand 4Department of Biochemistry and Immunology, Labtests, Auckland, New Zealand 5Department of Biochemistry, Middlemore Hospital, Auckland, New Zealand 6Starship Children’s Hospital, Auckland, New Zealand 7KidzFirst Children’s Hospital, Middlemore Hospital, Auckland, New Zealand 8Department of Microbiology, Middlemore Hospital, Auckland, New Zealand 9Department of Microbiology, LabPLUS, Auckland City Hospital, Auckland, New Zealand 10 Department of Microbiology, Labtests, Auckland, New Zealand Introduction: Serological assays for SARS-CoV-2 have a diagnostic role in situations where detection via molecular methods alone is insufficient, due to the timing and quality of sample collection. Serological assays must be assessed in the relevant epidemiological context, to determine locally-applicable sensitivity and specificity data. We present a comparison of nine serological assays conducted in Auckland, New Zealand. Methods: The nine assays evaluated were the Abbott Architect IgG, Roche Elecsys total antibody, Euroimmun IgA to Spike protein and IgG to Spike and nucleocapsid proteins, EDI IgM and IgG, in-house University of Auckland two-step ELISA and surrogate viral neutralisation assay (cPASS, GenScript). Pre-pandemic and pandemic (positive and negative RT-PCR) samples were tested on each assay, and sensitivity and specificity calculated. Pandemic samples were from inpatients to Auckland City Hospital and Middlemore Hospital March to May 2020. Results: With the exception of the IgA and IgM assays, the remaining seven assays demonstrated high specificity (94.2-100%) and reasonable sensitivity (86.7-100%). The in-house ELISA and cPASS assays performed best (100% sensitivity and specificity), but present challenges to implementation in diagnostic laboratories. The high- throughput Abbott and Roche assays
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