Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives

Total Page:16

File Type:pdf, Size:1020Kb

Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives U. S. DEPARTMENT OF HEALTH AND HUMAN SERVICES • Public Health Service • Alcohol, Drug Abuse, and Mental Health Administration Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives Editors: Robert J. Battjes, D.S.W. Roy W. Pickens, Ph.D. Division of Clinical Research National Institute on Drug Abuse NIDA Research Monograph 80 1988 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Alcohol, Drug Abuse, and Mental Health Administration National Institute on Drug Abuse 5600 Fishers Lane Rockville, MD 20857 For sale by the Superintendent of Documents, U.S. Government Printing Office Washington, DC 20402 NIDA Research Monographs are prepared by the research divisions of the National Institute on Drug Abuse and published by its Office of Science. The primary objective of the series is to provide critical reviews of research problem areas and techniques, the content of state-of-the-art conferences, and integrative research reviews. Its dual publication emphasis is rapid and targeted dissemination to the scientific and professional community. Editorial Advisors MARTIN W. ADLER, Ph.D. MARY L. JACOBSON Temple University School of Medrcrne National Federation of Parents for Philadelphia. Pennsylvania Drug-Free Youth Omaha, Nebraska SYDNEY ARCHER, Ph.D. Rensselaer Polytechnic Institute Troy, New York REESE T. JONES, M.D. Langley Porter Neuropsychiatric lnstitute RICHARD E. BELLEVILLE. Ph.D. San Francisco, California NB Associates, Health Sciences RockviIle, Maryland DENISE KANDEL, Ph.D. KARST J. BESTEMAN College of Physicians and Surgeons of Alcohol and Drug Problems Association Columbia University of North America New York, New York Washington, D. C. GILBERT J. BOTVIN, Ph.D. Cornell Unrversrty Medical College HERBERT KLEBER, M.D. Yale University School of Medicine New York, New York New Haven, Connecticut JOSEPH V. BRADY, Ph.D. The Johns Hopkins Unrversrty School of Medicine RICHARD RUSSO Baltimore, Maryland New Jersey State Department of Health Trenton, New Jersey THEODORE J. CICERO, Ph.D Washington University School of Medicine St Louis, Missouri NIDA Research Monograph Series CHARLES R. SCHUSTER, Ph.D. Director, NIDA THEODORE M. PINKERT, M.D.,J.D. Acting Associate Director for Science, NIDA Parklawn Building, 5600 Fishers Lane, Rockville, Maryland 20857 Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives ACKNOWLEDGMENT This monograph is based upon papers and discussion from a technical review which took place on May 18 and 19, 1987, at Bethesda, Maryland. The review meeting was sponsored by the Division of Clinical Research, National Institute on Drug Abuse. COPYRIGHT STATUS All material in this volume except quoted passages from copyrighted sources is in the public domain and may be used or reproduced without permission from the Institute or the authors. Citation of the source is appreciated. The views and opinions expressed on the following pages are solely those of the authors and do not necessarily constitute an endorse- ment, real or implied, by the U.S. Department of Health and Human Services. The U.S. Government does not endorse or favor any specific commer- cial product or company. Trade or proprietary names appearing in this publication are used only because they are considered essential in the context of the studies reported herein. DHHS publication number (ADM) 89-1567 Printed 1988, Reprinted 1989 NIDA Research Monographs are indexed in the Index Medicus. They are selectively included in the coverage of American Statistics Index, Biosciences Information Service, Chemical Abstracts, Current Contents, Psychological Abstracts, and Psychopharmacology Abstracts. iv Foreword Checking the spread of AIDS is the most urgent task confronting public health officials today. One in four persons with AIDS in the United States has used illicit drugs intravenously. Hence the National Institute on Drug Abuse (NIDA) has committed its re- sources on many fronts to help curb this deadly infection among intravenous drug abusers, their sexual partners, and their children. Transmission of the AIDS virus-human immunodeficiency virus (HIV)-among intravenous drug abusers most often occurs when they share drug injection equipment. Small amounts of contami- nated blood left in needles or syringes can carry the virus from person to person. Almost all intravenous drug users sometimes share their “works,” for reasons that include convenience, friend- ship, and ritual. In some cities in the United States, rates of HIV infection among intravenous drug users are already high. In many others, still in relatively early stages of the AIDS epidemic, a window of opportu- nity exists to prevent catastrophe. How can the risks from sharing injection equipment, commonplace among intravenous drug users, be reduced? How can individuals who are often hard to reach and unresponsive to “authority” be made aware of the danger and moti- vated to change long-established behaviors? To review existing research and program experience in dealing with these questions, NIDA convened more than 40 experts for a 2-day meeting in May 1987. They came from across the United States and from England, The Netherlands, and Italy, from governments, universities, treatment facilities, and professional associations. v Participants described a wide variety of programs and policies which have been implemented in U.S. cities and in Western Europe. They spoke from diverse perspectives and expressed dif- fering views. This monograph, summarizing the presentations at the meeting, is both informative and thought-provoking. lt can provide a valuable basis for further discussion about the challenging problem of stopping the spread of AIDS through “needle sharing.” Charles R. Schuster, Ph.D. Director National Institute on Drug Abuse vi Contents Page Foreword . v Participants . ix Needle Sharing Among Intravenous Drug Abusers: An Overview Robert J. Battjes and Roy W. Pickens . 1 Overview: HIV Infection Among Intravenous Drug Abusers in the United States and Europe Harry W. Haverkos. 7 Needle Sharing and Street Behavior in Response to AIDS in New York City William Hopkins. .18 The Ethnography of Needle Sharing Among Intravenous Drug Users and Implications for Public Policies and Intervention Strategies Harvey W. Feldman and Patrick Biernacki. .28 Mexican-American Intravenous Drug Users’ Needle-Sharing Practices: Implications for AIDS Prevention Alberto G. Mata and Jaime S. Jorquez . .40 Amsterdam’s Drug Policy and Its Implications for Controlling Needle Sharing Ernst C. Buning, Giel H.A. van Brussel, and Gerrit van Santen . , . .59 vii Page The Influence of AIDS Upon Patterns of Intravenous Use- Syringe and Needle Sharing-Among Illicit Drug Users in Britain Robert Michael Power . .75 Injecting Equipment Exchange Schemes in England and Scotland Gerry V. Stimson . .89 Sharing Needles and the Spread of HIV in ltaly’s Addict Population Enrico Tempesta and Massimo Di Giannantonio . 100 Drug Addiction and AIDS in France in 1987 Claude Olievenstein . 114 Intravenous Drug Abuse and AIDS Transmission: Federal and State Laws Regulating Needle Availability Chris B. Pascal . 119 Combining Ethnographic and Epidemiologic Methods in Targeted AIDS Interventions: The Chicago Model W. Wayne Wiebel . 137 Why Bleach? Development of a Strategy To Combat HIV Contagion Among San Francisco Intravenous Drug Users John A. Newmeyer. 151 The Sharing of Drug Injection Equipment and the AIDS Epidemic in New York City: The First Decade Don C. Des Jarlais, Samuel R. Friedman, Jo L. Sotheran, and Rand Stoneburner. 180 Needle Sharing Among Intravenous Drug Abusers: Future Directions Robert J. Battjes and Roy W. Pickens . 176 List of NIDA Research Monographs . 184 viii Participants National Institute on Drug Abuse Technical Review Meeting on Needle Sharing Among Intravenous Drug Abusers: National and lnternational Persectives, Bethesda MD, May 18-19, 1987 MODERATORS Don C. Des Jarlais, Ph.D. Assistant Deputy Director Robert J. Battjes, D.S.W. New York State Division of Associate Director for Planning Substance Abuse Services Division of Clinical Research 55 West 125th Street, 10th Floor National Institute on Drug Abuse New York, NY 10027 Parklawn Building, Room 10A-38 (212) 8708362 5600 Fishers Lane Rockville, MD 20857 Harvey W. Feldman, Ph.D. (301) 4436697 Executive Director Youth Environment Study, Inc. Roy W. Pickens, Ph.D. 1779 Haight Street Director, Division of San Francisco, CA 94117 Clinical Research (415) 751-4221 National Institute on Drug Abuse Parklawn Building, Room 10A-38 Harry W. Haverkos, M.D. 5600 Fishers Lane Chief, Clinical Medicine Branch Rockville, MD 20857 Division of Clinical Research (301) 4436697 National Institute on Drug Abuse Parklawn Building, Room 10A- REVIEWERS 5600 Fishers Lane Rockville, MD 20857 Ernst C. Buning, Psychologist (301) 443-1801 Drug Department GG & GD Valckenierstraat 2 1018 XG Amsterdam The Netherlands 01131 20 5555 349 ix William Hopkins, Ph.D. Robert Michael Power, Ph.D. Supervisor, Street Research Unit Research Fellow New York State Division of Drug Indicators Project Substance Abuse Services Department of Politics Vincent Building and Sociology 55 West 125th Street Birkbeck College New York, NY 10027 University of London (212) 8708501 16 Gower Street London, WC1, England Alberto G. Mata, Ph.D. 441 631 6246 Postdoctoral Fellow Center for Health Promotion Gerry V. Stimson, Ph.D. University of Texas Director, Monitoring
Recommended publications
  • Drug Threshold Enactments (2009-2015) 2015
    NCSL: Drug Threshold Enactments 2009-2015 Page | 1 Drug Threshold Enactments (2009-2015) 2015 Alabama SB 67 Lowers from a class C to class D felony first degree possession of marijuana if the person possesses marijuana for personal use after previously being convicted of certain marijuana possession offenses. Connecticut HB 7104 Reduces from a felony to a class A misdemeanor possession of any amount of illegal drug. Reduces from a felony to a class A misdemeanor possession of a half-ounce or more of marijuana. Kentucky SB 192 Creates a new class C felony of importing heroin and a new class B felony of aggravated trafficking in a controlled substance in the first degree if the substance trafficked was 100 grams or more of heroin. Increases the penalty from a class A misdemeanor to a class D felony for drug trafficking that involves more than 120 dosage units. Louisiana HB 149 Creates graduated penalties for first time possession of marijuana offenses by weight, reduces penalties for second and third convictions for possession of marijuana offenses, and creates a penalty for fourth conviction of possession of marijuana. • First offense possession of less than 14 grams of marijuana is punishable by not more than 15 days in jail and not more than $300. • First offense possession of more than 14 grams but less than two and a half pounds of marijuana is punishable by not more than six months jail and not more than $500. • Reduces second offense possession of marijuana from not more than 5 years and not less than $250 but not more than $2,000, to not more than 6 months in jail and nor more than $1,000.
    [Show full text]
  • HIV and Substance Use October 2016
    HIV and Substance Use October 2016 Fast Facts • Alcohol and other drugs can affect a person’s judgment and increase risk of getting or transmitting HIV. • In people living with HIV, substance use can worsen the overall consequences of HIV. • Social and structural factors make it difficult to prevent HIV among people who use substances. Substance use disorders, which are problematic patterns of using alcohol or another substance, such as crack cocaine, methamphetamine (“meth”), amyl nitrite (“poppers”), prescription opioids, and heroin, are closely associated with HIV and other sexually transmitted diseases. Injection drug use (IDU) can be a direct route of HIV transmission if people share needles, syringes, or other injection materials that are contaminated with HIV. However, drinking alcohol and ingesting, smoking, or inhaling drugs are also associated with increased risk for HIV. These substances alter judgment, which can lead to risky sexual behaviors (e.g., having sex without a condom, having multiple partners) that can make people more likely to get and transmit HIV. In people living with HIV, substance use can hasten disease progression, affect adherence to antiretroviral therapy (HIV medicine), and worsen the overall consequences of HIV. Commonly Used Substances and HIV Risk • Alcohol. Excessive alcohol consumption, notably binge drinking, can be an important risk factor for HIV because it is linked to risky sexual behaviors and, among people living with HIV, can hurt treatment outcomes. • Opioids. Opioids, a class of drugs that reduce pain, include both prescription drugs and heroin. They are associated with HIV risk behaviors such as needle sharing when injected and risky sex, and have been linked to a recent HIV outbreak.
    [Show full text]
  • Overland Park, Kansas Municipal Code Table of Contents Title 1 - General Provisions 1.01 Code Adoption
    Overland Park, Kansas Municipal Code Table Of Contents Title 1 - General Provisions 1.01 Code Adoption. 1.01.010 Generally. 1.01.020 Publication-Effect. 1.01.030 Short Title-Citation-Reference. 1.01.040 Reference Applies to Amendments. 1.01.050 Title, Chapter and Section Headings. 1.01.060 Reference to Specific Ordinances. 1.01.070 Supplements Authorized. 1.01.080 Effect of Code on Past Actions and Obligations. 1.01.090 Effective Date of Code. 1.01.100 Ordinance Book Designated. 1.01.110 Constitutionality. 1.04 General Provisions 1.04.010 Definitions. 1.04.020 Grammatical Interpretation. 1.04.030 Prohibited Acts Include Causing, Permitting, and Related Acts. 1.04.040 Construction. 1.04.050 Repeal Not To Revive Any Ordinances. 1.08 Right of Entry for Inspection 1.08.010 Regulations Generally. 1.12 General Penalty 1.12.010 Designated. 1.16 Ward Boundaries (Repealed) 1.16.010 Division - Boundaries - Renumbering - Boundary Adjustment. 1.20 Official Newspaper (Repealed) 1.20.010 Exemption from K.S.A. 13-1420. 1.20.020 Governing Body to Designate Official Newspaper. 1.20.030 Official Designation. 1.20.040 Official Newspaper To Have Been Published for a Year. 1.20.050 More Than One Official Newspaper. 1.24 Citations for Violations 1.24.010 Definitions. 1.24.020 Notice To Appear. 1.24.030 Time Specified. 1.24.040 Municipal Court. 1.24.050 Distribution of Notice. 1.24.060 Complaint To Be Filed. 1.24.070 Chapter Inapplicable To Certain Violations. Legal Basis for Overland Park, Kansas Title 2 - Administration and Personnel Page 1 2.09 City Manager/Governing Body Article I.
    [Show full text]
  • Advisory Council on the Misuse of Drugs
    ACMD Advisory Council on the Misuse of Drugs Chair: Dr Owen Bowden-Jones Secretary: Zahi Sulaiman 1st Floor (NE), Peel Building 2 Marsham Street London SW1P 4DF Tel: 020 7035 1121 [email protected] Sarah Newton MP Minister for Vulnerability, Safeguarding and Countering Extremism Home Office 2 Marsham Street London SW1P 4DF 10 March 2017 Dear Minister, RE: Further advice on methylphenidate-related NPS In February 2016, my predecessor Professor Les Iversen wrote to the then minister for Preventing Abuse, Exploitation and Crime, requesting that the Temporary Class Drug Order (TCDO) on seven methylphenidate-related Novel Psychoactive Substances be re-laid for a further 12 months. This TCDO was re-laid until June 2017, to allow the Advisory Council on the Misuse of Drugs (ACMD) more time to collect the evidence required to provide further advice for full control under the Misuse of Drugs Act 1971. The ACMD believes that the TCDO has been effective in reducing the prevalence of these substances and that the TCDO level of control was proportionate in the interim. I am now pleased to present to you the ACMD’s further advice on this matter in the enclosed report. The ACMD’s recommendation for full control applies to the seven substances currently controlled under the TCDO and extends to an additional five closely-related substances. These five similar substances have subsequently appeared on markets following the TCDO and are included in this advice due to their potential for similar harms. Recommendation The ACMD recommends that the
    [Show full text]
  • Texas Controlled Substances Act
    HEALTH AND SAFETY CODE TITLE 6. FOOD, DRUGS, ALCOHOL, AND HAZARDOUS SUBSTANCES SUBTITLE C. SUBSTANCE ABUSE REGULATION AND CRIMES CHAPTER 481. TEXAS CONTROLLED SUBSTANCES ACT SUBCHAPTER A. GENERAL PROVISIONS Sec.A481.001.AASHORT TITLE. This chapter may be cited as the Texas Controlled Substances Act. Acts 1989, 71st Leg., ch. 678, Sec. 1, eff. Sept. 1, 1989. Sec.A481.002.AADEFINITIONS. In this chapter: (1)AA"Administer" means to directly apply a controlled substance by injection, inhalation, ingestion, or other means to the body of a patient or research subject by: (A)AAa practitioner or an agent of the practitioner in the presence of the practitioner; or (B)AAthe patient or research subject at the direction and in the presence of a practitioner. (2)AA"Agent" means an authorized person who acts on behalf of or at the direction of a manufacturer, distributor, or dispenser. The term does not include a common or contract carrier, public warehouseman, or employee of a carrier or warehouseman acting in the usual and lawful course of employment. (3)AA"Commissioner" means the commissioner of state health services or the commissioner 's designee. (4)AA"Controlled premises" means: (A)AAa place where original or other records or documents required under this chapter are kept or are required to be kept; or (B)AAa place, including a factory, warehouse, other establishment, or conveyance, where a person registered under this chapter may lawfully hold, manufacture, distribute, dispense, administer, possess, or otherwise dispose of a controlled substance or other item governed by the federal Controlled Substances Act (21 U.S.C.
    [Show full text]
  • Treatment of Alzheimer's Disease and Blood–Brain Barrier Drug Delivery
    pharmaceuticals Review Treatment of Alzheimer’s Disease and Blood–Brain Barrier Drug Delivery William M. Pardridge Department of Medicine, University of California, Los Angeles, CA 90024, USA; [email protected] Received: 24 October 2020; Accepted: 13 November 2020; Published: 16 November 2020 Abstract: Despite the enormity of the societal and health burdens caused by Alzheimer’s disease (AD), there have been no FDA approvals for new therapeutics for AD since 2003. This profound lack of progress in treatment of AD is due to dual problems, both related to the blood–brain barrier (BBB). First, 98% of small molecule drugs do not cross the BBB, and ~100% of biologic drugs do not cross the BBB, so BBB drug delivery technology is needed in AD drug development. Second, the pharmaceutical industry has not developed BBB drug delivery technology, which would enable industry to invent new therapeutics for AD that actually penetrate into brain parenchyma from blood. In 2020, less than 1% of all AD drug development projects use a BBB drug delivery technology. The pathogenesis of AD involves chronic neuro-inflammation, the progressive deposition of insoluble amyloid-beta or tau aggregates, and neural degeneration. New drugs that both attack these multiple sites in AD, and that have been coupled with BBB drug delivery technology, can lead to new and effective treatments of this serious disorder. Keywords: blood–brain barrier; brain drug delivery; drug targeting; endothelium; Alzheimer’s disease; therapeutic antibodies; neurotrophins; TNF inhibitors 1. Introduction Alzheimer’s Disease (AD) afflicts over 50 million people world-wide, and this health burden costs over 1% of global GDP [1].
    [Show full text]
  • Epidemics of HIV, HCV and Syphilis Infection Among Synthetic Drugs
    www.nature.com/scientificreports OPEN Epidemics of HIV, HCV and syphilis infection among synthetic drugs only users, heroin-only users and Received: 7 November 2017 Accepted: 28 March 2018 poly-drug users in Southwest China Published: xx xx xxxx Shu Su1, Limin Mao 2, Jinxian Zhao3, Liang Chen3, Jun Jing4, Feng Cheng4 & Lei Zhang 1,4,5 The number of poly-drug users who mix use heroin and synthetic drugs (SD) is increasing worldwide. The objective of this study is to measure the risk factors for being infected with hepatitis C (HCV), human immunodefciency virus (HIV) and syphilis among SD-only users, heroin-only users and poly- drug users. A cross-sectional study was conducted in 2015 from a national HIV surveillance site in Southwest China, 447 poly-drug, 526 SD-only and 318 heroin-only users were recruited. Poly-drug users have higher drug-use frequency, higher rates of drug-sharing and unsafe sexual acts than other users (p < 0.05). About a third (36.7%) of poly-drug users experienced sexual arousal due to drug efects, which is higher than the rate among other drug users. Poly-drug users had the highest prevalence of HIV (10.5%) and syphilis (3.6%), but heroin-only users had the highest prevalence of HCV (66.0%) (all p < 0.05) among three groups. Logistic regression shows among poly-drug users, having sex following drug consumption and using drugs ≥1/day were the major risk factors for both HIV (Adjusted odds ratio (AOR) = 2.4, 95% CI [1.8–3.4]; 2.3, [1.6–3.1]) and syphilis infection (AOR = 4.1, [2.1–6.9]; 3.9, [1.8–5.4]).
    [Show full text]
  • Methylphenidate-Based
    ACMD Advisory Council on the Misuse of Drugs Chair: Professor Les Iversen Secretary: Zahi Sulaiman 1st Floor (NE), Peel Building 2 Marsham Street London SW1P 4DF Tel: 020 7035 1121 [email protected] Minister of State for Crime Prevention Home Office 2 Marsham Street London SW1P 4DF 31 March 2015 Dear Minister, I am writing to recommend that you lay a temporary class drug order (TCDO) pursuant to section 2A of the Misuse of Drugs Act 1971 on a number of methylphenidate-based NPS: ethylphenidate, 3,4-dichloromethylphenidate (‘3,4- DCMP’), methylnaphthidate (‘HDMP-28’), isopropylphenidate (‘IPP’ or ‘IPPD’) and propylphenidate. Methylphenidate-based NPS Methylphenidate is a licensed stimulant pharmaceutical and is controlled in the UK as a Class B controlled drug. The methylphenidate-related materials being marketed as NPS have psychoactive effects so similar to the parent compound that they can be expected to present similar risks to users. Although ethylphenidate is by far the most widely available of this group, other variants are already in the market place. In the short term, to address the widespread availability of methylphenidate-based NPS and the associated problems which are being reported, the ACMD has considered the evidence on methylphenidate-based NPS and recommends control of these NPS by means of a TCDO. The attached report contains the ACMD’s consideration of the evidence concerning methylphenidate-based NPS. 1 In providing this advice, I would like to convey my thanks to Police Scotland, the National Programme on
    [Show full text]
  • Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009–2010 Xizhong Cui,1 Leisha D
    RESEARCH Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009–2010 Xizhong Cui,1 Leisha D. Nolen,1 Junfeng Sun, Malcolm Booth, Lindsay Donaldson, Conrad P. Quinn, Anne E. Boyer, Katherine Hendricks, Sean Shadomy, Pieter Bothma, Owen Judd, Paul McConnell, William A. Bower, Peter Q. Eichacker This activity has been planned and implemented through the joint providership of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the American Nurses Credentialing Center (ANCC), the Accreditation Council for Pharmacy Education (ACPE), and the Accreditation Council for Continuing Medical Education (ACCME), to provide continuing education for the healthcare team. Medscape, LLC designates this Journal-based CME activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test with a 75% minimum passing score and complete the evaluation at http://www.medscape.org/journal/eid; and (4) view/print certificate. For CME questions, see page 175. Release date: December 15, 2016; Expiration date: December 15, 2017 Learning Objectives Upon completion of this activity, participants will be able to: 1. Assess recommendations for the management of systemic anthrax and the use of anthrax immune globulin intravenous (AIG-IV) 2. Distinguish variables associated with the application of AIG-IV in the current study 3.
    [Show full text]
  • The Context of HIV Risk Among Drug Users and Their Sexual Partners
    National Institute on Drug Abuse RESEARCH MONOGRAPH SERIES The Context of HIV Risk Among Drug Users and Their Sexual Partners 143 U.S. Department of Health and Human Services • Public Health Service • National Institutes of Health The Context of HIV Risk Among Drug Users and Their Sexual Partners Editors: Robert J. Battjes, D.S.W. Zili Sloboda, Sc.D. William C. Grace, Ph.D. NIDA Research Monograph 143 1994 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National Institutes of Health National Institute on Drug Abuse 5600 Fishers Lane Rockville, MD 20857 ACKNOWLEDGMENT This monograph is based on the papers from a technical review on “The Context of HIV Risk Among Drug Users and Their Sexual Partners” held on April 22-23, 1993. The review meeting was sponsored by the National Institute on Drug Abuse. COPYRIGHT STATUS The National Institute on Drug Abuse has obtained permission from the copyright holders to reproduce certain previously published material as noted in the text. Further reproduction of this copyrighted material is permitted only as part of a reprinting of the entire publication or chapter. For any other use, the copyright holder’s permission is required. All other material in this volume except quoted passages from copyrighted sources is in the public domain and may be used or reproduced without permission from the Institute or the authors. Citation of the source is appreciated. Opinions expressed in this volume are those of the authors and do not necessarily reflect the opinions or official policy of the National Institute on Drug Abuse or any other part of the U.S.
    [Show full text]
  • Supervised Injection Services: What Has Been Demonstrated?
    Drug and Alcohol Dependence 145 (2014) 48–68 Contents lists available at ScienceDirect Drug and Alcohol Dependence j ournal homepage: www.elsevier.com/locate/drugalcdep Review Supervised injection services: What has been demonstrated? ଝ A systematic literature review a,b,∗ c,d e a,b Chloé Potier , Vincent Laprévote , Franc¸ oise Dubois-Arber , Olivier Cottencin , a,b Benjamin Rolland a Department of Addiction Medicine, CHRU de Lille, Univ Lille Nord de France, F-59037 Lille, France b University of Lille 2, Faculty of Medicine, F-59045 Lille, France c CHU Nancy, Maison des Addictions, Nancy F-54000, France d CHU Nancy, Centre d’Investigation Clinique CIC-INSERM 9501, Nancy F-54000, France e Institute of Social and Preventive Medicine, University Hospital Center and University of Lausanne, Chemin de la Corniche 10, 1010 Lausanne, Switzerland a r t i c l e i n f o a b s t r a c t Article history: Background: Supervised injection services (SISs) have been developed to promote safer drug injection Received 18 May 2014 practices, enhance health-related behaviors among people who inject drugs (PWID), and connect PWID Received in revised form 14 October 2014 with external health and social services. Nevertheless, SISs have also been accused of fostering drug use Accepted 14 October 2014 and drug trafficking. Available online 23 October 2014 Aims: To systematically collect and synthesize the currently available evidence regarding SIS-induced benefits and harm. Keywords: Methods: A systematic review was performed via the PubMed, Web of Science, and ScienceDirect Supervised injection service databases using the keyword algorithm [(“SUPERVISED” OR “SAFER”) AND (“INJECTION” OR “INJECT- Safer injection facility ING” OR “SHOOTING” OR “CONSUMPTION”) AND (“FACILITY” OR “FACILITIES” OR “ROOM” OR “GALLERY” Supervised injecting center Drug consumption room OR “CENTRE” OR “SITE”)].
    [Show full text]
  • Prescription Stimulants
    Prescription Stimulants What are prescription stimulants? Prescription stimulants are medicines generally used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy— uncontrollable episodes of deep sleep. They increase alertness, attention, and energy. What are common prescription stimulants? • dextroamphetamine (Dexedrine®) • dextroamphetamine/amphetamine combination product (Adderall®) • methylphenidate (Ritalin®, Concerta®). Photo by ©iStock.com/ognianm Popular slang terms for prescription stimulants include Speed, Uppers, and Vitamin R. How do people use and misuse prescription stimulants? Most prescription stimulants come in tablet, capsule, or liquid form, which a person takes by mouth. Misuse of a prescription stimulant means: Do Prescription Stimulants Make You • taking medicine in a way or dose Smarter? other than prescribed Some people take prescription stimulants to • taking someone else’s medicine try to improve mental performance. Teens • taking medicine only for the effect it and college students sometimes misuse causes—to get high them to try to get better grades, and older adults misuse them to try to improve their When misusing a prescription stimulant, memory. Taking prescription stimulants for people can swallow the medicine in its reasons other than treating ADHD or normal form. Alternatively, they can crush narcolepsy could lead to harmful health tablets or open the capsules, dissolve the powder in water, and inject the liquid into a effects, such as addiction, heart problems, vein. Some can also snort or smoke the or psychosis. powder. Prescription Stimulants • June 2018 • Page 1 How do prescription stimulants affect the brain and body? Prescription stimulants increase the activity of the brain chemicals dopamine and norepinephrine. Dopamine is involved in the reinforcement of rewarding behaviors.
    [Show full text]