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Vol.11 No.2.Pmd 2009; 11 (2) : 103 INDIAN JOURNAL OF PRACTICAL PEDIATRICS • IJPP is a quarterly subscription journal of the Indian Academy of Pediatrics committed to presenting practical pediatric issues and management updates in a simple and clear manner. • Indexed in Excerpta Medica, CABI Publishing. Vol.11 No.2 APR.-JUN. 2009 Dr.K.Nedunchelian Dr. S. Thangavelu Editor-in-Chief Executive Editor CONTENTS FROM THE EDITOR'S DESK 109 TOPIC OF INTEREST - ORGAN TRANSPLANTATION Medico legal aspects of cadaveric organ donation and transplantation in India 112 - Chavda M, Cherian A, Abraham BK, Ramakrishnan N Renal transplantation in children 117 - Anil Vasudevan, Arpana Iyengar, Kishore Phadke Stem cell transplantation 127 - Nita Radhakrishnan, Yadav SP, Anupam Sachdeva Pediatric cardiothoracic transplantation: An update 136 - Rathinam S, Margabanthu G Hematopoietic stem cell transplantation in children with special reference to Indian Scenario 140 - Shipra Kaicker, Gauri Kapoor Corneal transplantation in children 153 - Priye Suman Rastogi, Bina John, Sujatha Mohan, Srinivas K Rao Pediatric liver transplantation with special reference to scenario in India 159 - Neelam Mohan Journal Office and address for communications: Dr. K.Nedunchelian, Editor-in-Chief, Indian Journal of Practical Pediatrics, 1A, Block II, Krsna Apartments, 50, Halls Road, Egmore, Chennai - 600 008. Tamil Nadu, India. Tel.No. : 044-28190032 E.mail : [email protected] 1 Indian Journal of Practical Pediatrics 2009; 11(2) : 104 INFECTIOUS DISEASES Update on rickettsial infections 172 - Arun Shah NEUROLOGY Febrile Seizures 177 - Kumaresan G DERMATOLOGY Childhood vitiligo - An overview 185 - Jayakar Thomas PICTURE QUIZ 190 RADIOLOGIST TALKS TO YOU Disorders of ventral induction and similar conditions - II 191 - Vijayalakshmi G, Elavarasu E, Vijayalakshmi M, Venkatesan MD CASE STUDY Stroke after primary varicella zoster virus infection 194 - Jayasree P, Pradeep, Chitra, Anand, Sukumaran TU Open lip schizencephaly causing childhood hemiparesis - A case report 197 - Basu M, Saha S, Banerjee T QUESTION AND ANSWER 200 CLIPPINGS 126,139,152,158,171,184,193 NEWS AND NOTES 176, 199 FOR YOUR KIND ATTENTION * The views expressed by the authors do not necessarily reflect those of the sponsor or publisher. Although every care has been taken to ensure technical accuracy, no responsibility is accepted for errors or omissions. * The claims of the manufacturers and efficacy of the products advertised in the journal are the responsibility of the advertiser. The journal does not own any responsibility for the guarantee of the products advertised. * Part or whole of the material published in this issue may be reproduced with the note "Acknowledgement" to "Indian Journal of Practical Pediatrics" without prior permission. - Editorial Board Published by Dr.K.Nedunchelian, Editor-in-Chief, IJPP, on behalf of Indian Academy of Pediatrics, from 1A, Block II, Krsna Apartments, 50, Halls Road, Egmore, Chennai - 600 008. Tamil Nadu, India and printed by Mr. D. Ramanathan, at Alamu Printing Works, 9, Iyyah Street, Royapettah, Chennai - 14. 2 2009; 11 (2) : 105 3 Indian Journal of Practical Pediatrics 2009; 11(2) : 106 4 5 Saturday, August 21, 2010 1:23:15 PM 5 Saturday, August 21, 2010 1:23:19 PM 2009; 11 (2) : 109 FROM THE EDITOR’S DESK This issue is dedicated to the subject of other regenerative tissues like hematopoeitic stem “Human organ and tissue transplantation”, cell transfusion . Many principles are involved a fascinating field and emerging as treatment with human organ and tissue transplantation, option for many end organ failures. necessitating very stringent ethical issues to be Transplantation of human organs and tissues can adhered with legal implications. Eventhough the be life saving and helps to restore vital functions indications for various organ transplantation are of otherwise incurable patients. same universally, the practice of opting for it is The harvesting of organs for transplantation very meager in developing countries when is dependent on a stringent definition of brain compared to developed ones. Reasons may be death. World Health Assembly sets guiding sociocultural unacceptability, financial constraint, principles emphasizing voluntary donation, lack of expertise, etc. For the organ non commercialisation, preference of cadaver transplantation to be successful it is mandatory over living donors and genetically related over to follow steps required, starting from donor as non related donors. The person whether recipient well as recipient selection, preparation, surgery or donor must be the main concern both as patient and life long immune suppression all of which and human being. The following general principles make the procedure tedious and expensive, may be adhered to: i) The organ to be recovered leading to failure if not adhered to strictly. In this from deceased person for the purpose of issue, medicolegal aspects of organ and tissue transplantation after obtaining consent. transplantation in general, information on ii) Physician certifying death of potential donor commonly practiced organ and tissue should not be directly involved in the organ transplantation are given. removal or subsequent transplantation and care Febrile seizures is one of the commonest of recipient. iii) Cadaver donation is preferable. neurological problems which creates anxiety In case of living donor, genetically related one is among parents and dilemma to pediatricians in better and exception may be bone marrow or diagnosis and to decide on treatment options. other regenerative tissue transplantation. Donors The article on “Febrile seizures” will answer many should be explained the risks, benefits and such queries. Some infections are not thought of consequences. iv) No organ is removed from routinely, among which rickettsial infections is an living minor, exception being the case of important one. A brief description of this infection regenerative tissues. v) Human body and tissues is done in the article “Update on rickettsial can not be the subject of commercial transactions; infections”. one should not engage in organ transplantation if there is commercial transactions. vi) Advertising Under the “Radiologist talks to you” column the need for an organ is prohibited. vii) Not to “Disorders of ventral induction and similar receive any payment that exceeds which is conditions”and under dermatology column, justifiable for the service rendered. viii) Donor “Vitiligo” are included. Two interesting cases, organs should be available to patients on the basis primary varicella zoster infection presenting as of medical need and not on financial or other stroke and schizencephaly presenting with considerations. seizures and hemiparesis are covered under the column of case studies. As this issue contains The organ transplantation once was most recent update on the subject of interest, we considered almost synonym with renal hope it will serve as a useful desk top reference transplantation. At the present context it is for years to come. considered as “organ and tissue transplantation” extending to many more organs like liver, heart, Dr. K.Nedunchelian, pancreas, etc and tissues like cornea as well as Editor-in-Chief. 7 Indian Journal of Practical Pediatrics 2009; 11(2) : 110 INSTRUCTIONS TO AUTHORS General Print the manuscript on one side of standard size A4, white bond paper, with margins of at least 2.5 cm (1”) in double space typescript on each side. Use American English using Times New Roman font 12 size. Submit four complete sets of the manuscript. They are considered for publication on the understanding that they are contributed to this journal solely. All pages are numbered at the top of the right corner, beginning with the title page. All manuscripts should be sent to: The Editor-in-Chief, Indian Journal of Practical Pediatrics Manuscript 1st Page – Title Name of the author and affiliation Institution Address for correspondence (Email, Phone, Fax if any) Word count No. of figures (colour / black and white) No. of references Authors contribution 2nd Page – Abstract (unstructured, not exceeding 100 words) with key words (not exceeding 4) 3rd Page - Acknowledgement Points to remember (not more than 5 points) Text References Tables Figures – should be good quality, 4 copies black & white / colour, (4 x 6 inches – Maxi size) Glossy print. (Each colour image will be charged Rs.1,000/- separately) Legends Text Only generic names should be used Measurements must be in metric units with System International (SI) Equivalents given in parentheses. References Recent and relevant references only Strictly adhere to Vancouver style Should be identified in the text by Arabic numerals in parentheses. Type double-space on separate sheets and number consecutively as they appear in the text. Defective references will entail rejection of article Tables Numbered with Roman numerals and typed on separate sheets. Title should be centered above the table and explanatory notes below the table. Figures and legends Unmounted and with figure number, first author’s name and top location indicated on the back of each figure. Legends typed double-space on separate sheet. No title on figure. 8 2009; 11 (2) : 111 Article Categories Review article Article should be informative covering the recent and practical aspects in that field. Main articles can be in 1500 – 2000 words with 12 – 15 recent references and abstract not exceeding 100 words. Case report (covering practical importance) 250 – 600 words, 8 – 10 recent references
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