:QH 431 .S692 10 1978 UNIVERSITY OF MISSOURI AGRICULTURAL EXPERIMENT STATION

STADLER GENETICS SYMPOSIA Volume 10

Edited by G.P. Redei

Columbia, Missouri 1978 COPYRIGHT 1978 The Curators of the University of Missouri ALL RIGHTS RESERVED

This book may not be reproduced, in whole or in part, except by reviewers for the public press, without written permission from the publisher.

LIBRARY OF CONGRESS CATALOG CARD NUMBER 79-635774

International Standard Book Number (Vol. 10) 0-912630-09-4

The ST ADLER GENETICS SYMPOSIA volumes are published by the Missouri Agricultural Experiment Station 117 Curtis Hall University of Missouri Columbia MO 65211 USA and may be purchased directly or through booksellers. The price of this volume is $5.00. Please remit also 50¢ for postage and handling. Missouri residents must pay an additional 20¢ for sales tax. Account Number 9738-2225 UNIVERSITY OF MISSOURI AGRICULTURAL EXPERIMENT STATION

STADLER GENETICS SYMPOSIA Volume 10

Edited by G.P. Redei

Columbia, Missouri 1978 2 STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia

ACKNOWLEDGEMENTS

The 10th Stadler Genetics Symposium was financed by the Department of Agronomy, the Division of Biological Sciences, the Graduate School and the School of Medicine of the University of Missouri-Columbia. The lecture of Dr. Norman H. Giles was made possible by the Donald M. Nelson Fund. The lectures of Dr. Barbara Mcclintock and Dr. c. S. Levings were sponsored by the u. S. Department of Agriculture, Agricultural Research Service, Mid-Plains Area. The Genetics Faculty and Students gratefully acknow­ ledge all the moral and financial support which make these annual Symposia possible.

The participants wish to express their thanks to Mrs. Mary Kay Doyle and to other wives of the Genetics Faculty who organized the social program with much success.

We owe gratitude to Professor Carolyn Kenneson and the Student String Quartetfor the f ine entertainment provided at the banquet.

Special thanks are due to Larry Dardick, David Estervig, Georgia Eizenga, Gary Peterson, and Jim Worstel who were in charge of the projection and earned the compliments of all the speakers. Larry Dardick also took some photographs of the Symposium.

Carol Irish assisted with typing of the Proceedings. Maribeth Jackson took care of most of the administrative chores of the Symposium. The financial matters of these Symposia are managed with care and efficiency by Fran Malloy. STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia 3

ST ADLER GENETICS SYMPOSIA CONTENTS VOLUME 10 (1978)

Acknowledgements • • • • • • 2 Contents • • • • • • • • • • 3 Participants • • • • • • • 4 E. R. Sears Scholarship Fund 8

Arthur Chovnick, Margaret Mccarron, Arthur Hilliker Janis O'Donnell, William Gelbart and Stephen Clark ORGANIZATION OF A GENE IN DROSOPHILA: A PROGRESS REPORT 9 Barbara Mcclintock MECHANISMS THAT RAPIDLY REORGANIZE THE · · · · · 25 Norman H. Giles, N. K. Alton, M. E. Case, J. A. Hautala, J. W. Jacobson, S. R. Kushner, V. B. Patel, W. R. Reinert, P. Str¢man and D. Vapnek THE ORGANIZATION OF THE QA GENE CLUSTER IN NEUROSPORA CRASSA AND ITS EXPRESS I ON IN ESCHERICHIA COLI • • • • • • • • • • 49 Janine Zieg, Michael Silverman, Marcia Hilmen and Melvin Simon PHASE VARIATION IN SALMONELLA: ANALYSIS OF THE CONTROLLING ELEMENT OF H2 GENE EXPRESSION 65 C. S. Levings, III and D. R. Pring THE MITOCHONDRIAL GENOME OF HIGHER PLANTS · · · · · · · · · 77 M. M. Green THE GENETIC CONTROL OF MUTATION IN DROSOPHILA 95 George P. Smith NON-DARWINIAN EVOLUTION AND THE BEARD OF LIFE 105 Cumulative Contents of the Proceedings of the Stadler Genetics Symposia •..••.•••• 122

THE VOLUMES OF THESE SYMPOSIA CAN BE ORDERED FROM 117 CURTIS HALL, UNIVERSITY OF MISSOURI, COLUMBIA MISSOURI, 65211. PRICE LIST AND CUMULATIVE CONTENTS ARE ON PAGES 122-124. EACH ORDER MUST INCLUDE AN ADDITIONAL 50¢ FOR POSTAGE AND HANDLING. MISSOURI RESIDENTS ARE REQUIRED TO PAY 4% SALES TAX. MAKE CHECKS PAYABLE TO STADLER GENETICS SYMPOSIA. 4 STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia

PARTICIPANTS

Acedo, Gregoria, 117 Curtis Hall, Columbia, MO Adhikary , Bharat, Box 4424, College Station, TX 77844 Agris, Paul F . , Div. Biol. Sci . , UMC, Columbia, MO Al berda, Brent, 1355 Kroeger Drive, St. Louis, MO Albert, Patrice, 106 Tucker Hall, UMC, Columbia, MO Allard, Lloyd, 430 West Adams, Apt. 4, Macomb , IL 61455 Allebrand, Ruth, Southern Ill. Univ., Carbondale, IL 62901 Altschuler, Marsha, Dept. of Biology, Indiana Univ., Bloomington, IN 47401 Amos, Jean, Dept. of Biology, Univ . Northern Iowa, Cedar Falls, IA 50613 Annan, Murve l, Wagner College, Staten Island, NY 10301 Apirion, David, Washl:ngton Univ. , St . Louis, MO Atherly, Alan, Dept . of Genetics, Iowa State U., Ames, IA 50010 Ausmus, Mike, William Jewell College, Liberty, MO 74068 Ayers, Arthur, 108 Waters Hall, UMC, Columbia, MO Ayers, Sandra, 108 Waters Hall, UMC, Columbia, MO Bailey, Tom, JR Browing Hall, William Jewell College, Liberty , MO 64068 Ball, Mary, 3090 W. Bowden, Auburn, Alabama 36830 Barnett, Robert, Washburn Univ . , Biol. Dept., Topeka, KS 66621 Bast, Sister Rose, Mount Mary College, Milwaukee, WI 53222 Beckett, Dorothy, 607 Longfellow Ln., Columbia, MO Beckett, Jack, 209 Curtis Hall, UMC, Columbia, MO Bennett, Vickie, 901 Sycamore Lane, Columbia, MO Biggers, Charles, Memphis State U. , Memphis, TN 38152 Bird, Robert, Missouri Botanical Gardens, 2345 Tower Grove, St. Louis, MO Bishop, Dean, Biology Dept., Pittsburg State U., Pittsburg, KS 66762 Blakey, Becky, Box 156, Wm. Woods College, Fulton, MO 65051 Bleistine, S. Helen, 102 E. 26th St., Bryan, TX 77801 Blizewski, Susan, 634B Hatch Hall, UMC, Columbia, MO Blythe, Gregory , 404 Lawrence Pl., Columbia, MO 65201 Boguslawski, George, Dept. of Microbiol., Univ. of KS, Lawrence, KS 66045 Bond, Lora, 1512 N. Washington Avenue, Springfield, MO 65803 Borek, Kate, Dept. of Biol., Washington u., St . Louis, MO 63130 Bozarth, Connie, 11 Aldeah, Columbia, MO 65201 Brase, Michael, 1405 West Blvd . South, Columbia, MO 65201 Brawn, Robert, 304 Hillside Lane, Bloomington, IL 61701 Breitenbach, R.P., UMC , Columbia, MO Brewer, Steven, Eaton Hall, Wm. Jewell College, Liberty, MO 64068 Bricker, Betsy, 547 Hawkeye Drive, Iowa City, IA 52240 Brooks, Margaret, Dept. of Biol., OK City Univ., Oklahoma City, OK 73106 Bryson, Vernon , Dept. of Biochem. Rutgers Univ., New Brunswick, NJ 03903 Bueno, Alvaro, 126-C Univ. Village, Ames, IA 50010 Burdick, Allan , 205 Curtis Hall, UMC, Columbia, MO Burkholder, John, McPherson College, McPherson, KS 67460 Burnham , Chas., 1539 Branst on St., St. Paul, MN 55108 Bussard, James, 304 Curtis Hall, UMC, Columbia, MO Bryant, S. M., Western IL Univ., Dept. Biology, Macomb, IL 61455 Buzard, Robert, 61 Southside Drive, Columbia, MO Caldwell, Steve, Southern IL Univ., Carbondale, IL 62901 Carlo, Mayra, UMC, Columbia, MO Carr, Bruce, 3125 Lafayette, St. Louis, MO 63104 castor, John H., r.ticrobiol., Southern IL Univ., Carbondale, IL 62901 Chapman, Linda, Biol., UMC, Columbia, no Chou, Tau-San, IL State u., Dept. of Biol., Normal, IL 61701 chovnick, A., University of Connecticut, Storrs, CN Christian, James, Dept. Bot. & Bacteriol., LA Tech. u., Ruston, LA 71270 citron, Bruce, Genetics Dept., u. of Iowaf Iowa City, IA 52242 Coe, Edward, 210 Curtis Hall, UMC, Columbia, MO Coe, Mary, 206 Heather Ln . , Columbia, MO . Coffey, Karen, ElY Hall, Wm. Jewell College, Liberty, MO cox, Thomas, 1006 Stafford Ave~ue, ~es, Iowa 500~0 Curtis, William, Washington Univ., Biol., St. Louis, MO 63130 Dardick, Larry, UMC, Columbia, MO David, John, UMC, Columbia, MO Demarini, David, Ill. State Univ., Normal, IL 61761 DeMars R , univ. Wisconsin, Madison , WI . WI 5 3 706 Demopuios:Rodriguez, J. T., Dept . of Genet. , Univ. Wisc., Madison, Denell, Robin, Div. of Biol., KS State U., Manhattan, KS 66506 Desborough, Sharon , Iforts Sci., u. Minnesota, St: Paul, MN 55108 Der, orchid, Sincl air Research Far~, UMC, Columbia, MO Dierberg, Jeff, 101 Burnam, Columbia, MO STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia 5

D~ 1 the au, ~ave, Westminster College, Fulton, MO Dilts, Judith, William Jewell College, Liberty, M.O 64068 Dlouhy, Stephen, 4339 D7claration o~., Indianapolis, IN 46227 Dooner, Hugo, B12 Genetics, U. of Wisconsin, Madison, WI 5 37 06 Dorsch, Stephen, UMC, 14D Univ . .Terr., Columbia, MO Doy le, Gregory, UMC, Columbia, MO Doyle, Mary Kaye, 1006 W. Rollins, Columbia, MO Dufek,. Debra, Dept. Biol. Sci., Western IL U., Macomb, IL 61455 Eaton, Brenda, 510 High St . , .UMC, Columbia, MO Edwards, G. A., 1703 Todd Trail, College Station, TX 77840 E~ner, Carol, 4550 Scott Ave . , Box 407, St. Louis, MO 63110 E~senstark, Abraham , UMC, Columbia, MO E~senstark, Ro~a, 2002 Valley View Rd., Columbia, MO Eizenga, Ge?rgia, 107 Curtis Hall, UMC, Columbia, MO Engel, Leslie, 613 N. 8th, Columbia, MO Engler~, DuWayne, Dept. of Zool. SIU, Carbondale, IL 62901 Estervig, Dave, 2707 Quail Drive, Columbia, no Feldman, Kenneth, Dept. Biol., UNI, Cedar Falls, Iowa 50613 Fenner, Dee, 233A Schurz, UMC, Columbia MO Fickess, Westminster College, Fulton, MO 65251 Ficsor, G., Dept. Biomed. Sci., WMU, Kalamazoo, MI 49008 Finnerty, Victoria, Emory University, Atlanta GA Fisher, Richard, Dept. Microbiol., U. of Iowa: Iowa City, IA 52240 Ford, Clark, 547 Hawkeye Drive, Iowa City, Iowa 52240 Forgey, Wm. M., 11 Gateway South, UMC, Columbia, Missouri Foundin, Laurie, UMC, B Keene St., Columbia, MO Fraser, Vicky, Box 339, Wm. Woods College, Fulton, MO 65251 Friedman, L., UMSL, St. Louis, MO Friedman, Scott, 908 Curtis Ave., Columbia, MO Fritschle, Carolyn, 12923 Topping Estates, St. Louis, MO 63131 Forlow, Lynn, Route 1, Rayville, MO 64084 Foureman, Polly, Dept. of Genet., U. of Wisc., Madison, WI 53706 Fuller, David, Mammalian Genet. Lab, u. of KN, Lawrence, KN 66044 Gardner, Candice, 312 Curtis Hall, UMC, Columbia, MO Gavan, James, 210 Switzler, UMC, Columbia, MO Gavan, Margaret, R.D. 2, Clark, MO 65243 Geekie, Karen, 313A Wolpers, UMC, Columbia, MO Ghora, Basanta, Washington u., Dept. Mi'crobiol. , Immunol., St. Louis, MO Giles, Norman H., University of Georgia, Athens, GA Gilmore, R. A., Dept. Biochem., Marshall u., Huntington, WV 25701 Godfrey, Joe, Washburn Univ., Biol. Dept., Topeka, Kansas 66621 Goudy, Joyce, Allegheny College, Meadville, PA 16 335 Gowans, Charles, 422 Tucker, UMC, Columbia, MO ~~:~~~,M~~: ~~A g~;~~;~ffy:~, UMC, cOlumbia, MO Green, M. M., University of California, Davis, CA Grether, David, 1406 8th Ave., North, St. Cloud, MN 56301 Grosberg, R., Ill. Benedictine College, Lisle, IL 60532 Grueber, Denyse, 313B Wolpers Hall, UMC, Colwnbia, MO Grula, John, Dept. Biol., U. of KS, Lawrence, KS 66045 Grula, Marge, Dept. of Biol., U. of KS, Lawrence, KS Grunau, John, Univ. of IL, Urbana, IL 63801 Hagood, Sue, College Ave., UMC, Columbia, MO 65201 Hake, Sarah, Dept. Biol., Washington U., St. Louis, MO 63130 Hale, Bill, Washburn, Univ., Biol. Dept., Topeka, KS 66621 Hamilton, John, 6611 N. Platte Hills Rd., Parkville, MO 64152 Hanks, Joanna, 108 Tucker Hall, UMC, Columbia, MO Harriman, Philip, UMKC, Kansas City, MO Hart, Gery, Texas A & M, College Station, TX Hash, Denise, Mammalian Genet. Lab, u. of KS, Lawrence, KS 66044 Hendrick, Phil, Div. Biol. Sci., u. of KS, Lawrence, KS 66045 Hellack, Jenna Jo, Biol. Dept., c.s.u., Edmond, OK Henderson, Betty, UMC, Columbia, MO flerrick, Carleton, Dept. of Biol., SEMS, Cape Girardeau, MO 63701 Hisey, Brent, Zoology Dept., OK u., Norman, OK 73019 Holcombe, Steven, Westminster College, Fulton, MO Horn, Michael, 707C Univ. Village, UMC, Columbia, MO Hough, Dan, Zool. Dept., u. of OK, Norman, OK 73069 Hyde, Beal, Dept. Bot., Univ. of VT, Burlington, VT 05401 Jamison, Kimberly, 456 Mississippi, Liberty, MO 64068 Jones, Bobby R., Southwestern at Memphis, Memphis, TN 38112 Jones, David, · UMC, Columbia, MO Jennings, Lisa, 750 Adams, Memphis, TN 38105 . Johnson, George, Dept. Biol., Washington U., St. Louis, MO 63130 Johnson, Terrell, Div. Biol., K. State, Manhattan, KS 66502 Jones Scott, William Jewell College, Liberty, MO 64068 Joseph Cindy, 105 Schweitzer Hall, UMC, Columbia, MO Kasuni~, Mark, Allegheny College, Meadville, PA . 16335 Kaufman, Thomas, Biol. Dept . , Indiana u., Bloomington, IN 4?401 Kavathas, Paula, Immunobiol. Research Center, U. of WI, Madison, WI 53705 Kazic, Toni, U. of PA, Philadelphia, PA 19104 Kemphues, Kenneth, Iowa University, Iowa City, IA Keppy, Dean, Iowa State, Ames, Iowa 50010 Kcrmicle, Jerry, U. of WI, Madison, WI Kant, narijo, Wm. Woods College, Fulton, MO Kikudome, Gary, UMC, 405 Tucker llall, Columbia, no 6 STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia

Kimber, Gordon, Curtis Hal~, UMC, Columbia, uo Kimber, Yvonne, 1201 Wo<;>dh1.ll Rd., Columbia, MO Kirsch, H ., UMC, Columbia, MO Kittilson~ H. L., B~ologi~al Sci., Univ. 'I'N, Martin, TN 38238 ~;~!~ka:~~t~~r!~ou~~~-C~~~~~:~t:~• U. of MN, St. Paul, MN 55108 Kuyper, Barbara, UMC, Columbia, MO Larson, Peggy, R.D. 4, Columbia, MO Larson, Russell, UMC, 304 Curtis Hall, Columbia MO Laver, Wm. R., Div. of Biol., Environ. Tr. Sub. 1 Centr., UMC, Columbia, MO Lawrence, Barry, 3524 Lincoln Way, Ames, Iowa 50010 Lawrence, Tommy, Dept. Biol., Memphis State u., Memphis, TN 38152 Leban, Karen, SIU, Carbondale, IL Lee, Daniel, UMC, Columbia, MO Lentsch, 7014 Walmer, Overland Park, KS 66204 LeFever, H. Michael, Emporia St., Emporia, KS 66801 Leslie, Ingelin, Madison, WI 53076 Leslie, John F., Dept . Genet., U. of WI, Madison, WI 53706 Leto, Kenneth, Univ. of IL, Urbana, IL Levings, C. S. , North Carolina State University, Raleigh, NC Liebman, Susan, U. of IL at Circle, Chicago, IL 60680 Lim, Johng, Genet. Lab, U. of WI, Madison, WI 53706 Lin, Victor, 121 S. 10th, UMC, Columbia, MO Longley, A. E., ._ 206 Heather, Columbia, MO Longwell, John, 306 Hitt, Apt. BA, Columbia, MO Longwell, Lorna, 306 Hitt, Apt. BA, Columbia, MO Loshman, Cathy, 1826 Pin Oak Dr., Cedar Falls, Iowa 50613 Lovett, Janice, 2530 W. 3rd St., Bloomington, IN 47401 Luerding, Chip, Wm. Jewell College, Liberty, MO 64068 Maham, James, Memphis State U., Dept. Biol., Memphis , TN 38111 Manoogian, Stan, Westminster College, Fulton, MO Maser, Robin, 6709 N. Flora, Kansas City, MO 64118 Master, Connie, UMC, Columbia, MO Mayes, Paul, Dept. of Zool., SIU, Carbondale, IL 62901 Meade, James, Dept. of Phys-ics, KSU, Manhattan, KS 66506 Mego , Wm., U. of IL, Chicago, IL 60680 Meyers, Steven, UMC, Columbia, MO Misra, Rachel, 221 S. 14 St., Murphysbobo, IL 62906 Mitchell, Joyce, UMC, Columbia, MO Mittler, Sidney , Biol. Dept., NIU, Dekalb, IL 60115 Mohamed, Aly, Biol. Dept . , UMKC , Kansas City, MO 64110 Monson, Arvid, Allegheny College, Meadville , PA 16335 Moore, Dana, Wm. Woods College, Fulton, MO 6525 1 Morris, Dantley, UMKC, Kansas City, MO Murnik, Mary, Dept. Biol. Sci., western IL u, Macomb, IL 61455 Murray, Elizabeth, 905 W. 29th St. Terr., Lawrence, KS Myers, Karen, Ely Hall, Wm. Jewell College, Liberty, MO 64068 Myers, Oval, Dept. Plant & Soil Sci., SIU, Carbondale, IL 62901 :~i!~~~~~~ 'B~~c~:~*:~i~Mi~s~~l=~t;g~~n, Cold Spring Harbor, Long Island, NY McCormick, Sheila, 210 Curtis Hall, UMC, Columbia, MO McDani el, Wayne, 908 Curtis Ave., UMC, Columbia, MO Neuffer, Margaret, 2000 Valleyview Rd., Columbia, MO Neuffer, M.G., Curtis Hall, UMC, Columbia, MO Nanney, Adrienno, Wm. Woods College, Fulton, MO Newman, Peter, UMC, Columbia, MO Newton, Kathleen, Biol. Dept., Indiana U., Bloomington, IN 47401 Nichols, UMC, Columbia, MO Nguyen, Manh Quoc, 209 Curtis Hall, UMC, Co lumbia, MO O'Leary, Tim, 909 Richmond, UMC, Columbia, MO Osterman, John, Dept. Biol., Indiana u., Bloomington, IN 47401 Owens, Ken, 7 Holiday Park, UMC, Columbia, MO Parchman, George, Memphis State U., Memphis, TN 38152 Parker, Tom, UMC, Columbia, MO Pauw, Peter, UMC, Columbia, MO Petersen, Arnold, St . Olaf College, Northfield, MN 55057 Peterson, G., UMC, Columbia, MO Pilles, i.tary, 548 w. Murray St., Macomb , IL 61455 Pittenger, Thad, Biol. Div., KSU, Manhattan, KS 66502 Playl, Timothy, 309 S. Schurz, UMC, Columbia, MO Polley, David, Dept. Biol., Wash. U., St. Louis, MO Pugashetti, B. K., Dept. Agron., UMC , Columbia, MO Quinnlian, Elaine, 111 Linwood Ave., Waterloo, Iowa 50702 Rafaill , Wm., Berea College, Dept. Biol., Berea, KY 40404 Rainbolt, chuck, 801 Mohawk, Independence, MO 64056 Rayburn, Lane, Dept. Plant Sci., Texas A & MU., C?llege Sta, TX 77843 Reddy, Arj ula, Dept. Biol. , Johns Hopkins U. , Baltimore, MD 21218 Redei, G. P., 117 Curtis Hall, UMC, Columbia, MO Re

Rodi, Charles, University of Minnesota Rodriguez, UMC, Biol. Sci. , Columbia, MO Roy, Paul, Dept. Biol. Sci., State U., Normal, IL Russell, Judi, Pittsburg State u., Pittsburg, KS 66762 Sakamoto, Winifred, UMC, Columbia, MO Salama, Nasr, Western Michigan u., Kalamazoo, MI 49007 Samson, Richard, 1600 Urbana Lane, Lincoln, HE 68505 Sandoxis, Christina, 4339 Mercier, K.C., MO 64111 Schaefer, Bradley, Zool. Dept., OU, Norman, OK 73019 Schmidt, Mike, SIU, Carbondale, IL 62901 Schultejans, Molly,407 Turner, UMC, Columbia, MO Schuppert, Hank, 502 Westminster Ave., Fulton, MO Scuba, James, 815 N.W. 13, Oklahoma City, OK 73106 Sears, Barbara, Duke Univ., Dept. Bot., Durham, NC Sears, E. S., UMC, Columbia, MO Sears, Lotti, UMC, Columbia, MO Shadley, Jeff, Illinois State u., Normal, IL 61761 Shellhard, Marsha, Wm. Jewell College, Liberty, MO 64068 Sherman, Louis, UMC, Columbia, MO Simmons, Patricia, UMC, Columbia, MO Simon, Phil, Hort. Dept., U. of WI, Madison, WI 55706 Slater, Jim, Box 316, Rt. 6, Neosho, MO 64850 Slife, David, 17 S. Jewell, Liberty, MO 64028 Smith, Danny, SIU, Carbondale, IL 62901 Smith, Charles, Zool. Dept., OU, Norman, OK 73019 Smith, George, Tucker Hall, UMC, Columbia, MO Smith, Jolynn, Dept. M.icrobiol., SIU, Carbondale, IL 62901 Snyder, John C., U. of MN, St. Paul, MN 55108 Spidle, Brenda, Wm. Jewell College, . Liberty, MO 64068 Stadler, Jody, 8 Curtiss Hall, Iowa State U., Ames, IA 50010 Stamberg, Judith, Genet. Dept., Washington U., St . Louis, MO Stansfield, David, UMC, Columbia, MO Steglich, Carolin, Genet. Dept., U . of WI, Madison, WI 53706 Stephenson, A. B., UMC, Columbia, MO Stock, Carolyn, UMC, Columbia, MO Stone, Joyce, 3161 Flint Dr., Memphis, TN 38118 Strickberger, Monroe, UMSL, St. Louis, MO Suhayda, Charles, 108 Waters Hall, UMC, Columbia, MO Suiter, Sarah, Stephens College, Columbia, MO Sustarsic, Dennis, Dept. of Med., Med. Coll. of Ohio, Toledo, OH 43699 Sustarsic, Schelly, 7251-B Lunitas Ln., Perrysburg,. Ohio 43551 Swanson, Margaret, 106 Tucker Hall, UMC, Columbia, MO Thom, Sophie, Mount Mary College, Milwaukee, WI 53222 Thompson, James N., Jr., Dept. of Zool., OU, Norman, OK 73019 Tollefson, A., UMC, Columbia, MO Tomlinson, Thomas, Washburn Univ. • , Biol. Dept., Topeka, KS 66621 Toothman, Penny, Biol. Dept., Washington Univ., St. Louis, MO 63130 Toney, Joe V. , Zoology Dept. , OU, Norman, OK 73019 Tuan, James, Berea College, Dept. of Biol., Berea, Kentucky 40404 Tuitmire, Ann, Wm. Jewell College, Liberty, MO Ullrich, Robert, Dept. of Bot., u. of Vt . , Burlington, VT 05401 Unander, Dave, SIU, Carbondale, IL 62901 Voss, Deward, 1645 N. Spanish, Cape Girardeau, MO 63701 Wagoner, Dale, Dept. of Biol., Maharishi Int. U., Fairfield, IA 52556 Uakimoto, Barbara, Dept. of Biol., Indiana U., Bloomington, IN 47401 Walbot, Virginia, Dept. of Biol., Washington U., St. Louis, MO 63130 Walro, Leanne, Allegheny College, Meadville, PA 16 335 Wang, Richard, Dalton Research Center, UMC, Columbia, MO Wang, Wei Yeh, Dept. of Bot., U. of Iowa, Iowa City, IA 52242 Warren, Thomas, 1434 Kinser PK., Bloomington, IN 47401 Watkins, Penny, Wm. Jewell College, Liberty, MO 64068 Weber, David, Dept. of Biol. Sci., IL St. U . , Normal, IL 61761 Weir, John, Dept. Physiol. & Cell Biol., U. of KS, Lawrence, KS Welter, Richard, P.O. 268, Ames, IA 50010 Werthnulle, Wm. Woods College, Fulton, MO Whale, R. H., Biol. Sept., SD State U., Brookings, SD 5 7006 Williams, Larry c., Div. of Biol . , Kansas State U., Manhattan, KS Wilson, Wells, Westminster College, Fulton, MO Wixom, Robert, Dept . of Biochem., UMC, Columbia, MO Wolf, Thomas, Biol. Dept., Washburn u., Topeka, KS 66621 Wolfe, H. Glenn, Dept. Physiol. & Cell Biol., Lawrence, KS 6604 5 Worstell, J., UMC, Columbia, MO Wronkiewicz, Dept. Biol . Sci., Western ILU., Macomb, IL 6145 5 wurst, Glen, Allegheny Colle ge, Meadville, PA 16335 Yand ers, A. F., UMC, Columbia, MO Zacher, Allan, UMC, Columbia, MO Zieg, J., Univ. California, La J o lla, CA Zimme rman, Greta, Wm. Jewell College, Lib erty, MO 64068 Zuber, Bernice, 2211 Bushnell, Columbi a , MO Zuber, M. S., Ur.IC, Curtis Hall, Columbia, MO 8 STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia

R. S eaM Sc.ho .tcw, hip Fu.nd The. Etl.nv.,t R. Se.a.M Sc.ho.la.Mlup Fund, e.1.,.ta.bwhe.d by- Ve.an EmeJr,Wv., John H. Longwe,U a.nd M,v.,. LOJtna. Longwei.l , ,u., in­ te.nde.d to -6timui.a,te. 1te1> e.Mc.h a.nd -6 c.lwla./t-6 hip in Ge.ne.tic.-6 in the. -6piltit 06 the. c.onbu..bution-6 60Jt V1t. Se.a.M to -6c.ie.nc.e., e.-6Hn;tla..t to the. de.ve.lopme.nt o 6 Ag/tic.ui...twte.. The. divide.nd-6 06 the. Fund will be. w., e.d :to -6uppoltt a.nd Jte.c.ognize. a. gJta.dua:te. -6:tu.de.nt oft 6a.c.u..tty- me.mbe.Jt 601t uho.la.Mlup a.nd 1te.-6e.a1tc.h in Ge.ne.tic.-6 • The. Fund ,u., a.dmlnb.,:te.1te.d by- :the Se.a./t-6- Longwe,U Awa.ltd Commli­ te.e.. The. a.nnu.a..t a.wa1td-6 will be. p!te.-6 e.n:te.d a.t :the. S.ta.d.te.Jt Ge.ne.tic.-6 Sy-mpo-6ia.. 16 y-ou would Uke. :to join in :tlu-6 explte.-6-6ion honolting V1t. S e.a./t-6 , ple.a.-6 e. -6 e.nd y-oUlt c.o ntltibutio n :to :

ERNEST R. SEARS FUND 117 Curtis Hall University of Missouri Columbia', Missouri 65201

During 1978, by November 29, contributions were received from: Edward H. Coe, Jr. Abraham Eisenstark Luther B. Hughes Susan W. Liebman Gordon Kimber G. P. Redei Dale Sechler Robert & Sonya Ullrich Armon F. Yanders STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia 119

Speakers and other participants of the 10th Stadler Symposium, 1978 120 STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia

Dr. Sheila McCormick, a 1978 graduate, the first recipient of the E. R. SEARS SCHOLARSHIP AWARD. The Fund has been established by Dean Emeritus John H. Longwell and Mrs. Lorna Longwell STADLER SYMP . Vol. 10 (1978) University of Missouri, Columbia 121

Dean Longwell, Sheila McCormick, and Dr. Sears at the presentation of the LONGWELL-SEARS SCHOLARSHIP AWARD at the banquet of the 10th Stadler Genetics Symposium 122 CUMULATIVE CONTENTS OF THE PROCEEDINGS VOLUMES 1 and 2 •1971• 176 pages ($6.00) G. P. REDEI: A Portrait of L. J. Stadler 1896-1954 CURT STERN: From Crossing-Over to Developmental Genetics C. C. LINDEGREN: Biology and Biochemistry: Thesis and Antithesis T. S. PAINTER Chromosomes and Genes Viewed from a Perspective of Fifty Years Research A.H. DOERMANN: Bacteriophage T4, the Present Concept of the Gene A. H. STURTEVANT: On the Choice of Material for Genetical Studies RUTH SAGER and ZENTA RAMANIS: Formal Genetic Analysis of Organelle Genetic Systems LYNN MARGULIS: Cytoplasmic Genes - Our Precambrian Legacy S. FOGEL, D. D. HURST and R. K. MORTIMER: Gene Conversion in Un­ selected Tetrads from Multipoint Crosses G. W. BEADLE: Genes, Intelligence and Education W. J. Peacock: Cytogenetic Aspects of the Mechanism of Recom­ bination in Higher Organisms C. M. RICK: Some Cytogenetic Features of the Genome in Diploid Plant Species. VOLUME 3 116 pages ($4.00) R. W. ALLARD and A. L. KAHLER: Allozyme Polymorphisms in Plant Populations DAVID SCHLESSINGER: Repertoire of Genetic Control of Gene Ex­ pression in Procaryotes ALLAN R. GOLDBERG and JERARD HURWITZ: The Catalytic Role of rho in Termination During In Vitro DNA-Dependent RNA Synthesis HAMPTON L. CARSON: Speciation and the Founder Principle TIBOR RAJHATHY: The Alloploid Model in Avena JEROME A. SCHIFF: The Informational and Nutritional Requirements of Cellular Organelles VOLUME 4 136 pages ($4.00) HERMAN W. LEWIS: Trends in Genetics Research - Prospects for Development E. R. SEARS: Chromosome Engineering in Wheat ROBERT P. WAGNER: Evolution and Genetic Significance of Mitochondria STEPHEN H. HOWELL: The Biochemistry of Meiosis and Genetic Recom- bination G. F. SPRAGUE: The Genetics of Corn Breeding LEON S. DURE III and WILLIAM C. MERRICK: The Role of tRNA in Development SHELDON C. REED and V. ELVING ANDERSON: Genetics of Psychoses CHARLES F. MULLETT: Seven (or Twenty-Seven) Against Obscurity or Still Further Observations on Tittlebats STADLER SYMP. Vol. 10 (1978) University of Missouri, Columbia 123 VOLUME 5 •1973• 188 pages ($4.00) M. M. RHOADES: A Portrait of E. G. Anderson 1891-1973 ELOF A. CARLSON: Eugenics Revisited: The Case for Germinal Choice H. ROMAN: Studies of Recombination in Yeast A. EISENSTARK: Tryptophan Photoproduct as a Genetic Probe: Effects on Bacteria R. P. LEVINE: Membranes and Mutations in Chlamydomonas reinhardi LEE HOOD: The Genetics, Evolution and Expression of Antibody Molecules R. D. HOTCHKISS: Genetic Unity and Biochemical Diversity in Genetic Recombination Mechanisms A. TOMASZ: DNA Uptake by Bacteria and Eucaryotic Cells R. H. HODGES: Judges, Genes and Man VOLUME 6 •1974• 168 pages ($4.50) G. UNGAR: Molecular Coding of Information in the Nervous System 0. W. MCBRIDE: Metaphase Chromosome Uptake by Mammalian Cells and Expression of the ·Genes Transferred T. T. PUCK: The Genetics of Somatic Mammalian Cells R. H. DAVIS: Metabolic Organization in Neurospora P. S. CARLSON and T. B. RICE: Developmental Genetics and Crop Yield B. A. HAMKALO, 0. L. MILLER, JR. and A. H. BAKKEN: Electronmicro- scopic Studies of Active Genes C. S. GOWANS: Genetics and Art G. P. REDEI, G. ACEDO and G. GAVAZZI: Flower Differentiation in Arabidopsis VOLUME 7 •1975• 168 pages ($5.00) ERWIN CHARGAFF: A Few Remarks on the Impact of Biochemistry on Genetics ROBERT B. HELLING: Eukaryotic Genes in Prokaryotic Cells OLUF L. GAMBORG: Advances in Somatic Cell Hybridization in Higher Plants RICHARD B. FLAVELL and DEREK B. SMITH: Genome Organization in Higher Plants NOBORU SUEOKA: Genetic Transformation as a Tool in the Studies of DNA Replication and Recombination GEORGE B. JOHNSON: Enzyme Polymorphism and Adaptation ALLAN C. WILSON: Evolutionary Importance of Gene Regulation C. DONALD MILES: Genetic Analysis of Photosynthesis DEANE. METTER: Natural Selection and Adaptive Resemblance VOLUME 8 182 pages ($5.00) DREW SCHWARTZ: Regulation of the Alcohol Dehydrogenase Genes In JOHN W. DRAKE: Mutagenic Mechanisms in Bacteriophage T4 ARNOLD L. DEMAIN: Genetic Regulation of Fermentation Organisms 124 STADLER SYMP. Vol. 10 (1978) University of Missouri, Co lumbia

0 . P. SEHGAL and C.H. HSU: RNA:Protein and Protein:Protein Inter­ actions in the Virions of Southern Bean Mosaic JAMES E . CARREL: Aphrodisiacs and Anaphrodisiacs: Better Loving Through Chemistry ALFRED R. LOEBLICH, III : Dinoflagellate Genetics and DNA Char- acterization DAVID APIRION : Genetic Approaches to the Study of Ribosomes DAVIDE. PETTIJOHN: DNA Packaging in Isolated Bacterial Nucleoids ANTHONY CERAMI: The Development of New Drugs for Genetic .Diseases VOLUME 9 •1977• 218 pages ($5.00) JAMES W. ALLEN, CHARLES F. SHULER, and SAMUEL A. LATT : Extension of BrdU-Dye Analysis of DNA Replication and Sister Chr omatid Exchange Formation to In Vivo Systems G. GAVAZZI: The Genetic Complexity of the R Locus in Maize , JAMES N. THOMPSON, JR.: Analysis of Gene Number and Developm~nt in Polygenic Systems HIROFUMI UCHIMIYA, KEVIN CHEN and S . G. WILDMAN: Polypeptide Composition of Fraction I Protein as an Aid in the Study of Plant Evolution DONALD L. RIDDLE: A Genetic Pathway for Dauer Larva Formation in Caenorhabditis elegans WINSTON J. BRILL: Genetics of Nitrogen Fixation RUTH KAVENOFF and BRIAN C. BOWEN: On the Organization of DNA in Isolated Bacterial Chromosomes J. R. S. FINCHAM: A Gene-Enzyme Relationship in Neurospora GARY STEIN, JANET STEIN, LEWIS KLEINSMITH, WILLIAM PARK, JUDITH THOMSON, ROBERT JANSING, ELIZABETH SHEPHARD and SIEGFRIED DETKE : Chromatin as a Model System for Studying the Regula­ tion of Histone Gene Expression in ·Mammalian Cells MOSHE FELDMAN : Historical Aspects and Significance of the Discov­ ery of Wild Wheats VOLUME 10 •1978• 124 pages ($5.00) ARTHUR CHOVNICK, MARGARET MCCARRON, ARTHUR HILLIKER, JANIS O'DONNELL, WILLIAM GELBART and STEPHEN CLARK: Organization of a Gene in Drosophila: A Progress Report BARBARA McCLINTOCK: Mechanisms that Rapidly Reorganize the Genome NORMAN H. GILES, N. K. ALTON, M. E. CASE, J. A. HAUTALA, J. W. JACOBSON, S. R. KUSHNER, V. B. PATEL, W.R. REINERT, P. STR0MAN and D. VAPNEK: The Organization of the QA Gene Cluster in Neurospora crassa and its expression in Escherichia coli JANINE ZIEG, MICHAEL SILVERMAN, MARCIA HILMEN and MELVIN SIMON: Phase Variation in Salmonella: Analysis of the Controlling Element of H2 Gene Expression C. S. LEVINGS, III and D. R. PRING: The Mitochondrial Genome of Higher Plants M. M. GREEN: The Genetic Control of Mhtation in Drosophila GEORGE P. SMITH: Non-D1rwinian Evolution and the Beard of Life

~ ORDER FROM 117 CURTIS HALL, UNIVERSITY: OF MISSOURI, COLUMBIA MO 65211 DUE RETURNED

Form 104A

QH 431 .S692 10 1978 N03316