Subchapter M—International Traffic in Arms Regulations
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
A Guide to Export Controls
Foreign Affairs, Trade and Affaires étrangères, Commerce et Development Canada Développment Canada A Guide To CANADA’S EXPORT CONTROLS December 2012 Introduction The issuance of export permits is administered by the Export Controls Division (TIE) of Foreign Affairs, Trade and Development Canada (DFATD). TIE provides assistance to exporters in determining if export permits are required. It also publishes brochures and Notices to Exporters that are freely available on request and on our website www.exportcontrols.gc.ca. How to contact us: Export Controls Division (TIE) Foreign Affairs, Trade and Development Canada 111 Sussex Drive Ottawa, Ontario K1A 0G2 Telephone: (613) 996-2387 Facsimile: (613) 996-9933 Email: [email protected] For information on how to apply for an export permit and additional information on export controls please refer to our website. To enquire on the status of an export permit application: Recognized EXCOL users can check the status of an export permit application on-line. Non-recognized users can call (613) 996-2387 or email [email protected] and quote your export permit application identification (ref ID) number. Export Controls Division website: www.exportcontrols.gc.ca This Guide, at time of publication, encompasses the list of items enumerated on the Export Control List (ECL) that are controlled for export in accordance with Canadian foreign policy, including Canada’s participation in multilateral export control regimes and bilateral agreements. Unless otherwise specified, the export controls contained in this Guide apply to all destinations except the United States. Canada’s Export Control List can be found at the Department of Justice website at http://canada.justice.gc.ca/. -
Of 10 October 2018 Amending Council Regulation (EC) No 428/2009
14.12.2018 EN Official Journal of the European Union L 319/1 II (Non-legislative acts) REGULATIONS COMMISSION DELEGATED REGULATION (EU) 2018/1922 of 10 October 2018 amending Council Regulation (EC) No 428/2009 setting up a Community regime for the control of exports, transfer, brokering and transit of dual-use items THE EUROPEAN COMMISSION, Having regard to the Treaty on the Functioning of the European Union, Having regard to Council Regulation (EC) No 428/2009 of 5 May 2009 setting up a Community regime for the control of exports, transfer, brokering and transit of dual-use items ( 1), and in particular Article 15(3) thereof, Whereas: (1) Regulation (EC) No 428/2009 requires dual-use items to be subject to effective control when they are exported from or transit through the Union, or are delivered to a third country as a result of brokering services provided by a broker resident or established in the Union. (2) Annex I to Regulation (EC) No 428/2009 establishes the common list of dual-use items that are subject to controls in the Union. Decisions on the items subject to controls are taken within the framework of the Australia Group ( 2 ), the Missile Technology Control Regime ( 3 ), the Nuclear Suppliers Group ( 4 ), the Wassenaar Arrangement ( 5 ) and the Chemical Weapons Convention. (3) The list of dual-use items set out in Annex I to Regulation (EC) No 428/2009 needs to be updated regularly so as to ensure full compliance with international security obligations, to guarantee transparency, and to maintain the competitiveness of economic operators. -
Pyridoxine in Clinical Toxicology: a Review Philippe Lheureux, Andrea Penaloza and Mireille Gris
78 Review Pyridoxine in clinical toxicology: a review Philippe Lheureux, Andrea Penaloza and Mireille Gris Pyridoxine (vitamin B6) is a co-factor in many enzymatic controversial. This paper reviews the various indications pathways involved in amino acid metabolism: the main of pyridoxine in clinical toxicology and the supporting biologically active form is pyridoxal 5-phosphate. literature. The potential adverse effects of excessive Pyridoxine has been used as an antidote in acute pyridoxine dosage will also be summarized. intoxications, including isoniazid overdose, Gyromitra European Journal of Emergency Medicine 12:78–85 mushroom or false morrel (monomethylhydrazine) c 2005 Lippincott Williams & Wilkins. poisoning and hydrazine exposure. It is also recommended as a co-factor to improve the conversion of glyoxylic acid European Journal of Emergency Medicine 2005, 12:78–85 into glycine in ethylene glycol poisoning. Other indications Keywords: Antidotes, crimidin, drug-induced neuropathy, ethylene glycol, are recommended by some sources (for example crimidine hydrazine, isoniazid, metadoxine, pyridoxine poisoning, zipeprol and theophylline-induced seizures, adjunct to d-penicillamine chelation), without significant Department of Emergency Medicine, Erasme University Hospital, Brussels, Belgium. supporting data. The value of pyridoxine or its congener Correspondence to Philippe Lheureux, Department of Emergency Medicine, metadoxine as an agent for hastening ethanol metabolism Erasme University Hospital, 808 route de Lennik, 1070 Brussels, Belgium. or improving vigilance in acute alcohol intoxication is E-mail: [email protected] Introduction ing. More controversial issues include alcohol intoxication Pyridoxine or vitamin B6 is a highly water-soluble and zipeprol or theophylline-induced seizures. vitamin. Its main biologically active form is a phosphate ester of its aldehyde form, pyridoxal 5-phosphate (P5P). -
Gyromitrin Poisoning: More Questions Than Answers
Gyromitrin poisoning: more questions than answers Denis R. Benjamin, MD some dedicated mycophagist, who had Many of these clues to the toxin never eaten the mushroom for many years made any coherent sense, even though it “It is perhaps ironic for a mushroom, without any ill effects, would suddenly was known for some years that the toxins Gyromitra esculenta, whose very name and unaccountably take ill. This too could be destroyed by cooking.” (From means edible, to be so poisonous under was passed off as the development of an Benjamin, 1995.) certain circumstances. Surprisingly, allergy in the unfortunate individual, the toxins were only characterized as that the mushrooms had been mistaken ll the enigmas related to this recently as 1968. A number of factors for a poisonous variety, or a rotten toxin remain unresolved. The conspired against the investigators of this batch had been eaten. To compound the current literature merely repeats mushroom poison (Lincoff and Mitchel, difficulties, Gyromitra esculenta caused Awhat was published before 1990. A 1977). The first was the observation that many poisonings in Europe, while in the deluge of “cut and paste.” No meaningful only a few of the participants eating the western USA, the seemingly identical research has been done in the past same quantity of the same mushroom species appeared largely harmless. All three decades. This is due to a number would become ill. Because of this, the sorts of explanations were proposed of factors. The first was the demise of poisoning was immediately ascribed to to explain this discrepancy, including academic pharmacognosy departments, ‘allergy’ or ‘individual idiosyncrasy.’ The such fanciful ones as suggesting that responsible for investigating the biology next problematic observation was that Americans cook their vegetables better. -
Toxicological Profile for Hydrazines. US Department Of
TOXICOLOGICAL PROFILE FOR HYDRAZINES U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Agency for Toxic Substances and Disease Registry September 1997 HYDRAZINES ii DISCLAIMER The use of company or product name(s) is for identification only and does not imply endorsement by the Agency for Toxic Substances and Disease Registry. HYDRAZINES iii UPDATE STATEMENT Toxicological profiles are revised and republished as necessary, but no less than once every three years. For information regarding the update status of previously released profiles, contact ATSDR at: Agency for Toxic Substances and Disease Registry Division of Toxicology/Toxicology Information Branch 1600 Clifton Road NE, E-29 Atlanta, Georgia 30333 HYDRAZINES vii CONTRIBUTORS CHEMICAL MANAGER(S)/AUTHOR(S): Gangadhar Choudhary, Ph.D. ATSDR, Division of Toxicology, Atlanta, GA Hugh IIansen, Ph.D. ATSDR, Division of Toxicology, Atlanta, GA Steve Donkin, Ph.D. Sciences International, Inc., Alexandria, VA Mr. Christopher Kirman Life Systems, Inc., Cleveland, OH THE PROFILE HAS UNDERGONE THE FOLLOWING ATSDR INTERNAL REVIEWS: 1 . Green Border Review. Green Border review assures the consistency with ATSDR policy. 2 . Health Effects Review. The Health Effects Review Committee examines the health effects chapter of each profile for consistency and accuracy in interpreting health effects and classifying end points. 3. Minimal Risk Level Review. The Minimal Risk Level Workgroup considers issues relevant to substance-specific minimal risk levels (MRLs), reviews the health effects database of each profile, and makes recommendations for derivation of MRLs. HYDRAZINES ix PEER REVIEW A peer review panel was assembled for hydrazines. The panel consisted of the following members: 1. Dr. -
Synthetic and Naturally Occurring Hydrazines As Possible Cancer Causative Agents
[CANCER RESEARCH 35, 3693-3697 December 1975] Synthetic and Naturally Occurring Hydrazines as Possible Cancer Causative Agents Bela Toth' The Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska 68105 SUMMARY SYNTHETIC HYDRAZINES The various synthetic substituted hydrazines, which cause tumors in animals, are briefly enumerated. To date, 19 of Studies on the carcinogenic potentialities of synthetic them have proved to be tumorigenic in animals. A number substituted hydrazines began in 1962, when it was shown of these chemicals are found today in the environment, in that the base compound hydrazine sulfate induced lung industry, in agriculture, and in medicine, and the human neoplasms in mice (1). Subsequently, a series of hydrazine population is exposed to a certain degree to some of them. derivatives were investigated in various laboratories for Hydrazine also occurs in nature in tobacco and tobacco tumor-inducing capabilities. These studies clearly demon smoke. The three other naturally occurring hydrazine strated that these chemicals are indeed powerful tumori compounds are N-methyl-N-formylhydrazine, which oc genic substances in mice, hamsters, and rats, due to their curs in the wild edible mushroom, Gyromitra esculenta, tumor-inducing abilities in the intestines, brain, lungs, and @-N-[―y-L(+)-glutamylJ-4-hydroxymethylphenyl blood vessels, liver, breasts, kidneys, etc. Now, we know of hydrazine and 4-hydroxymethylphenylhydrazine, whkh 19 hydrazine derivatives that have been shown to be tumor are found in the commonly eaten cultivated mushroom, inducers. These include, in addition to hydrazine (1, 32), Agaricus bisporus. Tumorigenesis studies with the natu methyl- (35, 40), 1,2-dimethyl- (6, 27, 36, 46, 52), 1,1- rally occurring hydrazines are in progress. -
Hydrazine 1 Hydrazine
Hydrazine 1 Hydrazine Hydrazine Identifiers [1] CAS number 302-01-2 , 7803-57-8 (hydrate) [2] EC number 206-114-9 UN number 2029 (anhydrous) 2030 (aq. soln., 37–64%) 3293 (aq. soln., <37%) RTECS number MU7175000 Properties Molecular formula N H 2 4 Molar mass 32.05 g/mol (anhydrous) 50.06 g/mol (hydrate) Appearance Colourless liquid Density 1.0045 g/cm3 (anhydrous) 1.032 g/cm3 (hydrate) Melting point 1 °C (274 K, anhydrous) -51.7 °C (hydrate) Boiling point 114 °C (387 K), anhydrous 119 °C (hydrate) Solubility in water miscible Acidity (pK ) 8.1 a Refractive index (n ) [3] D 1.46044 (22 °C, anhydrous) 1.4284 (hydrate) Viscosity 0.876 cP (25 °C) Structure Hydrazine 2 Molecular shape pyramidal at N [4] Dipole moment 1.85 D Hazards [5] MSDS ICSC 0281 EU Index 007-008-00-3 EU classification Carc. Cat. 2 Toxic (T) Corrosive (C) Dangerous for the environment (N) R-phrases R45, R10, R23/24/25, R34, R43, R50/53 S-phrases S53, S45, S60, S61 NFPA 704 Flash point 52 °C Autoignition 24–270 °C (see text) temperature Explosive limits 1.8–100% LD [6] 50 59–60 mg/kg (oral in rats, mice) Related compounds Related nitrogen hydrides Ammonia Hydrazoic acid Related compounds monomethylhydrazine dimethylhydrazine phenylhydrazine [7] (what is this?) (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references Hydrazine is an inorganic chemical compound with the formula N H . It is a colourless liquid with an 2 4 ammonia-like odor and is derived from the same industrial chemistry processes that manufacture ammonia. -
Role of Electrodes in Ambient Electrolytic Decomposition of Hydroxylammonium Nitrate (HAN) Solutions
Propulsion and Power Research 2013;2(3):194–200 http://ppr.buaa.edu.cn/ Propulsion and Power Research www.sciencedirect.com ORIGINAL ARTICLE Role of electrodes in ambient electrolytic decomposition of hydroxylammonium nitrate (HAN) solutions Kai Seng Koha, Jitkai China,n, Tengku F. Wahida Ku Chikb aFaculty of Engineering, University of Nottingham Malaysia Campus, Semenyih, Selangor 52000, Malaysia bNational Space Agency Malaysia (ANGKASA), Putrajaya, Wilayah Persekuatuan 62570, Malaysia Received 13 April 2013; accepted 17 June 2013 Available online 27 August 2013 KEYWORDS Abstract Decomposition of hydroxylammonium nitrate (HAN) solution with electrolytic decomposition method has attracted much attention in recent years due to its efficiencies and Electrolytic decomposition; practicability. However, the phenomenon has not been well-studied till now. By utilizing Hydroxylammonium mathematical model currently available, the effect of water content and power used for nitrate (HAN); decomposition was studied. Experiment data shows that sacrificial material such as copper or Copper wire; aluminum outperforms inert electrodes in the decomposition of HAN solution. In the case of using Inert carbon rod; copper wire to electrolyse HAN solutions, approximately 10 seconds is required to reach 100 1C Electrode regardless of concentration of HAN. In term of power consumption, 100 W–300 W was found to be the range in which decomposition could be triggered effectively using copper wire as electrodes. & 2013 National Laboratory for Aeronautics and Astronautics. Production and hosting by Elsevier B.V. All rights reserved. 1. Introduction n Hydroxylammonium nitrate (HAN), with the chemical Corresponding author: Tel.: +60 173310400. formula NH OHNO , has been widely recognized as a E-mail address: [email protected] (Jitkai Chin). -
Doping-Induced Detection and Determination of Propellant Grade Hydrazines by a Kinetic Spectrophotometric Method Based on Nano and Conventional Polyaniline Using Halide Ion
RSC Advances This is an Accepted Manuscript, which has been through the Royal Society of Chemistry peer review process and has been accepted for publication. Accepted Manuscripts are published online shortly after acceptance, before technical editing, formatting and proof reading. Using this free service, authors can make their results available to the community, in citable form, before we publish the edited article. This Accepted Manuscript will be replaced by the edited, formatted and paginated article as soon as this is available. You can find more information about Accepted Manuscripts in the Information for Authors. Please note that technical editing may introduce minor changes to the text and/or graphics, which may alter content. The journal’s standard Terms & Conditions and the Ethical guidelines still apply. In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains. www.rsc.org/advances Page 1 of 12RSC Advances RSC Advances Dynamic Article Links ► Cite this: DOI: 10.1039/c0xx00000x www.rsc.org/xxxxxx ARTICLE TYPE Doping-induced Detection and Determination of Propellant Grade Hydrazines by Kinetic Spectrophotometric Method based on Nano and Conventional Polyaniline using Halide ion Releasing Additives† Selvakumar Subramanian, *,a Somanathan Narayanasastri b and Audisesha Reddy Kami Reddy a 5 Received (in XXX, XXX) Xth XXXXXXXXX 20XX, Accepted Xth XXXXXXXXX 20XX DOI: 10.1039/b000000x A kinetic spectrophotometric method is described for the detection and determination of propellant grade hydrazines and its derivatives based on their reaction with 1-Chloro-2,4-dinitrobenzene (CDNB) incorporated in a solution matrix of Polyaniline-Emaraldine Base (Pani-EB) to produce HCl. -
Characterization & Analysis On
CHARACTERIZATION & ANALYSIS ON ELECTROLYTIC DECOMPOSITION OF HYDROXYLAMMONIUM NITRATE (HAN) TERNARY MIXTURES IN MICROREACTORS CHAI WAI SIONG, BEng. Thesis submitted to the University of Nottingham For the degree of Doctor of Philosophy 2017 1 | P a g e Abstract Rapid development of micropropulsion systems arose from growing interest on micro- and nanosatellites. Utilization of liquid energetic materials such as hydrazine and hydrogen peroxide as propellant in propulsion yielded promising results. However, safety issue remains a great concern as hydrazine is highly toxic. This drives the development of propellants towards lower toxicity and more environmental friendly, namely green propellants. Hydroxylammonium nitrate (HAN) was selected among three green propellants due to its high energy density in addition to ease in storage and handling properties. In order to understand the effect of addition of fuel into HAN binary solution, electrolytic decomposition of zero oxygen balance HAN ternary mixture in thermal isolated beaker was performed at macroscale. Addition of a fuel to binary HAN solution generally has more stages of decomposition, as opposed to single stage in binary HAN solution. Rate of temperature increase in the first stage of decomposition (Ṫ1) was found to be directly proportional to electrical resistivity of the HAN ternary mixture, while maximum electrolytic decomposition temperature (Tmax) of HAN ternary mixture obtained was dependent on fuel added. Visualization of HAN decomposition was demonstrated using transparent PDMS microreactors. A novel DPST integration in triggering the power supply and high speed camera was proposed. Such 2 | P a g e integration greatly reduced the cost of using a DAQ system, and was shown to capture the decomposition successfully at 5000 fps. -
Hydrazine, Monomethylhydrazine, Dimethylhydrazine and Binary Mixtures Containing These Compounds
Fluid Phase Behavior from Molecular Simulation: Hydrazine, Monomethylhydrazine, Dimethylhydrazine and Binary Mixtures Containing These Compounds Ekaterina Elts1, Thorsten Windmann1, Daniel Staak2, Jadran Vrabec1 ∗ 1 Lehrstuhl f¨ur Thermodynamik und Energietechnik, Universit¨at Paderborn, Warburger Straße 100, 33098 Paderborn, Germany 2 Lonza AG, Chemical Research and Development, CH-3930 Visp, Switzerland Keywords: Molecular modeling and simulation; vapor-liquid equilibrium; Henry’s law constant; Hy- drazine; Monomethylhydrazine; Dimethylhydrazine; Argon; Nitrogen; Carbon Monoxide; Ammonia; Water Abstract New molecular models for Hydrazine and its two most important methylized derivatives (Monomethyl- hydrazine and Dimethylhydrazine) are proposed to study the fluid phase behavior of these hazardous compounds. A parameterization of the classical molecular interaction models is carried out by using quan- tum chemical calculations and subsequent fitting to experimental vapor pressure and saturated liquid density data. To validate the molecular models, vapor-liquid equilibria for the pure hydrazines and binary hydrazine mixtures with Water and Ammonia are calculated and compared with the available experimen- tal data. In addition, the Henry’s law constant for the physical solubility of Argon, Nitrogen and Carbon Monoxide in liquid Hydrazine, Monomethylhydrazine and Dimethylhydrazine is computed. In general, the simulation results are in very good agreement with the experimental data. ∗ corresponding author, tel.: +49-5251/60-2421, fax: +49-5251/60-3522, email: [email protected] 1 1 Introduction On October 24, 1960, the greatest disaster in the history of rocketry, now also known as Nedelin disaster, occurred [1–3]. At that time, the Soviet newspapers published only a short communique informing that Marshall of Artillery Mitrofan Nedelin has died in an airplane crash. -
(12) United States Patent (10) Patent N0.: US 6,218,577 B1 Brand Et Al
US006218577B1 (12) United States Patent (10) Patent N0.: US 6,218,577 B1 Brand et al. (45) Date of Patent: Apr. 17, 2001 (54) ENEGETIC HYDRAZINIUM SALTS (58) Field Of Search ............................. .. 564/464; 149/36, 149/122 (75) Inventors: Adam J. Brand, Palmdale; Gregory W. Drake, Lancaster, both of CA (US) (56) References Cited (73) Assignee: The United States of America as US' PATENT DOCUMENTS represented by the Secretary of the 3,297,747 * 1/1967 Thornton et al. .................. .. 564/310 Air Force, Washington, DC (US) 3,314,837 * 4/1967 Heubusch . .. 525/410 4,310,696 * 1/1982 Hojo et al. ......................... .. 564/464 ( * ) Notice: Subject to any disclaimer, the term of this . * cited b examiner patent is extended or adJusted under 35 y U_S,C, 154(b) by 0 days, Primary Examiner—Johann Richter Assistant Examiner—Brian J. Davis (21) APPL NO; 09/356,227 (74) Attorney, Agent, or Firm—Thomas C. Stover (22) Filed: Jul. 16, 1999 (57) ABSTRACT Provided is a salt of hydroXyethylhydraZine of Related US. Application Data [HO—CH2—CH2—NH2—NH2+][X_] or [HO—CH2— (60) Provisional application No. 60/093,733, ?led on Jul. 20, 1998. CH2—NH2—NH32+][X_]2, Where X=NO3, c104, N(NO2)2 or C(NO2)3 and method of making same. (51) Int. Cl.7 ................................................. .. C07C 241/02 (52) US. Cl. ............................................................ .. 564/464 19 Claims, N0 Drawings US 6,218,577 B1 1 2 ENEGETIC HYDRAZINIUM SALTS HO—CH2—CH2—NH—NH2+m HXQ[HO—CH2— CH2—NH2—NH2+][X_] or [HO—CH2—CH2—NH2— This application claims priority from US.