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www.inst.ac.in C o n t e n t s S. No. Title Pages

1 From the Desk of Director 1-2 2 Vision, Mission, Objecves and Funcons 03 3 Decision Making Bodies 04 4 Academics programme at INST 05 5 Message from Prof Ashok K Ganguli: Founding Director, INST 06 6 Research Facilies at INST 7-9 7 Research at INST I. Chemical Biology and Therapeuc 10-24 II. Nanostructured Devices 25-33 III. Nanotechnology for Energy and Environment 34-45 IV. So Nanostructure 46-52 8 Some of Research Highlights 53-55 9 Funding @ INST 56-59 10 Publicaons from INST 60-69 11 Lecture at INST Mohali 70-71 12 Foreign visit of INST Faculty 72-74 13 Conferences/Workshop Organised by INST 75-82 14 Parcipaon of INST in various events 82-85 15 Outreach @ INST 86-89 16 Other Acvies @INST 89-94 17 Awards and Honors to INST 94-95 18 INST-Industry partnership 96-100 19 Human resource (scienfic & administraon) 101-102 20 Financial accounts 103-120

FROM THE DESK OF DIRECTOR

I joined this Instute as Scienst – G from Bhabha Atomic Research Centre (BARC), Mumbai and presently holding the charge of Director (Offg.) aer the successful compleon of tenure of Prof Ganguli. I feel both pleased and privileged to present you the Sixth Annual Report of INST, Mohali. This report presents outlines, achievements and progress of INST in the past year. In addion, the report provides an update on the status of our endowment and financial results for the 2017-2018 fiscal year. In the past five years, INST has grown from an idea to an instuon, and is ready to take its place with other leading scienfic instuons in the country, but differenates for aiming beyond discovery research. INST has unique foundaonal elements to support its mission. Our young and enthusiasts, well-trained faculty, have a spectrum of scienfic strength that can bridge basic to applied sciences and translaonal research. Our commitment is to focus on cung edge research in the area of science and technology, besides build academia-industry collaboraons to support industrial research, and develop technologies that would address government iniated programs like Swatchh Bharat and Swasth Bharat. This year also marks the compleon of the long and successful tenure of Prof Ashok K Ganguli, the Founding Director of INST, under whose dynamic leadership the Instute has built such naonally unique capabilies and accorded internaonal recognion in the field of nano science and technology. On behalf of INST family, I would like to place on record our great respect and appreciaon for his commendable efforts in bringing INST to these heights. Under its Ph D programme, INST has started 10 Ph.D. courses in associaon with IISER Mohali and Panjab University (as degree awarding Universies/Instutes) for enrollment of PhD students. Currently, INST has 121 PhD students and 11 Post-doctoral students.

The faculty has made significant scienfic contribuons as reflected by the quality as well as number of research publicaons from INST over the last 05 years. Since its incepon, INST has published more than 200 papers in reputed internaonal journals.

The instute has made significant progress in terms of developing new materials and processes and progressing a number of technologies towards transfer to industry contribung to the Make in India campaign.

During the year, INST faculty have filed four patents on Nanoadsorbents for removal of Lanthanide ions from water; Cellulose-metallothionein conjugate for metal binding; Graphene-CNT nanohybrid aptasensor for label free detecon of cardiac biomarker myoglobin; Efficient ferlizer delivery through mesoporous silica. Some of the patents which are under the process of filing are: Extracon of zinc oxide from baery waste and their ink formulaon, Removal of phosphate ions from water, Extracon of silica nanoparcles from industrial waste, Nanoadsorbents for removal of metal ions and organic impuries. 01 Institute of Nano Science And Technology

The growing number of extra-mural projects has offered a high level of vibrancy, energy and compeve spirit to the campus. A total of 62 sponsored-research projects, including 4 industrial projects have been sanconed amounng to INR ~30.70 crores. During the financial year 2017-18, a total of 19 sponsored-research projects have been sanconed amounng to INR ~22.55 crores (2017-18). Most of the projects are focused on applicaon-oriented research of societal relevance.

During the period reported upon, INST has also signed MoUs with Naonal Agri-Food Biotechnology Instute (NABI), Mohali, Centre for Innovaon and Advanced Biology (CIAB), Mohali (an autonomous instute under Department of Biotechnology, Ministry of Science and Technology, Government of India). Both the instutes have agreed to provide some laboratory space in their buildings.

In addion to technology and process development, INST has also demonstrated its ability to contribute significantly in promong science and inculcang the pracce to develop technology in India amongst the young generaon of the naon through its amazing and unparalleled outreach program in any research instute of India. Chhatra Protsahan Vyakhyan Shrankhla (CPVS), North East Educaonal Development (NEED), Outreach programme for Women, School adopon programme are some of the iniaves taken since its incepons under the banner of Outreach Programme. Nearly 270 schools (~18,500 students) from rural and remote areas were covered in the last three years in 18 states including Assam, Andhra Pradesh, Chhasgarh, J&K, Kerala, Himachal Pradesh, Meghalaya, Rajasthan, Orrisa, Punjab, Haryana, , Uar Pradesh, Uarakhand etc. under the various outreach programmes.

Construcon of INST's state-of-the-art main campus has started in January this year and is expected to be completed within two years of me. Now, the execuon of work is in full swing and is expected to be completed by end of 2019.

I take this opportunity to thank all the employees for their unsnted cooperaon, dedicated efforts in accomplishing the set targets and commitments for their innovaon. I would like to place on record the connuous support provided by DST and the key role played by the Board Of Governors (BoG), Research Academic Advisory Council(RAAC), Finance Commiee and Building Works Commiee (BWC) in providing the right policy support, encouragement and guidance. The contribuons of various commiee members in steering the R&D programmes in the right direcon are noteworthy.

(Hirendra Nath Ghosh)

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2. Vision, Mission, Objecves and Funcons

VISION MISSION To emerge as globally To be a world class research instuon by carrying out cung-edge compeve India's foremost research through outstanding sciensts from different branches of research instuons in Nano science and engineering, encouraging them to carry out their Science and Technology and individual scienfic research to be published in the best journals along to contribute to the society with their mandate to jointly work on interdisciplinary projects to through applicaons of develop devices/technologies based on nano science and technology. n a n o s c i e n c e a n d To encourage all aspects of nanoscience and nanotechnology with nanotechnology in the field major thrust on the following areas: agricultural nanotechnology, of agriculture, medicine, sensors, medical nanotechnology, nanotechnology based soluons energy and environment. for energy and environment. The ulmate goal is to make a difference to society through nanoscience and technology.

OBJECTIVES Ø Encouraging innovave and challenging Ø Resource building – infrastructure and technology/product based scienfic manpower projects Ø Enhance research acvity in Nano Science and Ø Publish scienfic papers in the best journals Nano Technology Ø Generang patents in Nano Science and Ø Training students in PhD programme in Nano Technology Science and Technology Ø Encouraging translaonal research (from Ø Foster interacons between leading sciensts laboratory to industry) of the world in Nano Science and Technology Ø Special thrust to innovate and to apply Ø Impart advanced training courses and science for benefit to society laboratory techniques of nanotechnology at Ø Sensizing public and media about the the highest level advantages and safeguards in Nano Science Ø O rga n iz in g imp o rta nt n a o n a l a n d and Technology internaonal level seminars and conferences FUNCTIONS To facilitate the growth of understanding of developing technologies, which are globally compeve acclaimed level. Efforts shall be carried on relentlessly by supporng and encouraging young researchers and sciensts with state-of-the-art infrastructure and through a challenging work environment. Though all aspects of nanoscience and nanotechnology will be encouraged, some of the key research projects of the instute would be as follows: Ø Water purificaon, Water spling and Carbon Ø Nanostructures for Li-ion baeries dioxide sequestering Ø Flexible electronics Ø Carbon based nanostructures & devices Ø Smart polymers Ø Band-gap engineering for efficient solar Ø Devices based on 2 D nanostructures photo-catalysts Ø Interacve nano-packaging for extending Ø Thermal insulaon and thermoelectronics food shelf lives Ø Low-cost microfluidic devices for food, Ø Cancer Nano therapeucs security, health and agriculture Ø Tissue engineering for research, products targeng wound heali

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3. Decision Making Bodies BOARD OF GOVERNORS (BOG) Chairperson: Bharat Ratna, Prof. CNR Rao Prof. Ashutosh Sharma Dr. K. VijayRaghavan Sh. Vinay Sheel Oberoi Secretary, Dept. of Higher Secretary, DST Secretary, DBT Educaon, MHRD Dr. Trilochan Mohapatra Shri Anuj Kumar Bishnoi Prof. A. K. Sood Secretary (DARE) & Secretary,Department of Chemicals and IISc, Bangalore Director General (ICAR) Petrochemicals, New Delhi Prof. Shankumar V. Nair, Prof. V. Ramgopal Rao Prof. M.K. Sanyal AIMS, Kochi Director, IIT, Delhi SINP, Dr. J.K. Arora Sh. A.S.Miglani Prof. D P Sarkar Execuve Director Secretary, Punjab Govt. Director, IISER Mohali PSCST, Chandigarh Dept. of Sc., Tech. and Env. Prof. Avinash C Pandey Sh. J.B. Mohapatra Prof. A.K. Ganguli Director, IIDS, University JS & FA, DST Director, INST Mohali of Allahabad, Allahabad

Shri U. C. Prasad CFAO, INST, Mohali Member-Secretary

RESEARCH AND ACADEMIC ADVISORY COUNCIL (RAAC) Chairperson : Prof. Krishna N Ganesh, Director , IISER, Tirupa Members DR. ANAND K BACHHAWAT DR. VIJAYAMOHAN K PILLAI Professor (Biology) Director, CSIR-Central ElectroChemical IISER, Mohali Research Instute, Karaikudi DR. BODH RAJ MEHTA DR. JATINDER KAUR ARORA Member Execuve Director Schlumberger Chair Professor Punjab State Council for Science Indian Instute of Technology Delhi & Technology (PSCST) Dr. P. S. ANIL KUMAR PROF. UMESH V. WAGHMARE Associate Professor Theorecal Sciences Unit Department of Physics Jawaharlal Nehru Centre for Advanced Indian Instute of Science, Bangalore Scienfic Research, Bangalore

PROF. ASHOK K GANGULI DR. PRAKASH P. NEELAKANDAN Director, Instute of Nano Science Member-Secretary and Scienst E and Technology, Mohali Instute of Nano Science and Technology

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4) Academics Programme at INST : PHD PROGRAMME : INST, Mohali has a comprehensive PhD programme that gives enthusiasc and movated students, the opportunity to join the highly compeve global research community. INST offers an exceedingly high degree of intellectual freedom to students allowing them to pursue their individual interests within the four broader areas of research conducted at the Instute. Students at INST, Mohali are registered for their PhD degree with IISER, Mohali and also Panjab University, Chandigarh. Currently 100 PhD students are working (93 are registered at IISER Mohali and 7 at Panjab University). Specialized PhD Degree on Nanoscience and Technology INS651: Biomolecular interacons: Spectroscopic and calorimetric methods INS652: Characterizaon of nanomaterials INS653: Chemistry of Nanomaterials: Synthesis, Properes and Applicaons INS654: Electron Microscopy INS655: Photoluminescence spectroscopy with emphasis on applicaons in Material Science including nanomaterials INS656: Biomolecular self-assembly. INS657: Chemistry of nanomaterials: Synthesis, properes and applicaons INS658: Nanobiotechnology and nanomedicine: Basics and applicaons INS659: Thermal properes at Nanoscale. INS660: Plasmonics and its applicaons IDC601: Seminar course POSTDOCTORAL FELLOWSHIP PROGRAMME: INST also offers a postdoctoral fellowship programme, which is open for applicaons from the diverse field of Nano Science and Technology. This fellowship is inially offered for a period of two years and usually extended to three, following review. Postdoctoral fellows are expected to work independently and have complete academic freedom in the sense that they can choose their own research problem and collaborator. Post-Doctoral Fellows will work in interdisciplinary major projects with faculty of INST. Interested candidates should have strong research interest in Nano Science and Technology (Drug delivery, sensors, energy, agriculture, water purificaon, scanning probe microscopy, high resoluon electron microscopy, smart materials, devices, microfluidics, industrial and societal technologies). The fellowship carries a consolidated monthly spend of Rs.45,000/- besides a conngency grant of Rs.40,000/- per annum. Candidates who have submied their Ph.D. thesis but are yet to be awarded the PhD degree, if selected, will be paid Rs. 25,000/- per month ll the award of the degree. Special internship opportunity for General/SC - ST candidates: Instute of Nano Science and Technology, Mohali also provides an opportunity to exceponally good undergraduate students to execute an innovave research and development project under the guidance of INST faculty. The students from different instuons including IITs, NITs, IISERs, Central Universies as well as several State Universies across the country have been carrying out their research internships at INST. Currently, INST is also encouraging students to carry out research internship who have their own fellowship awarded from IASc-INSA-NASI Summer Research Programme as well as Inspire Programme (DST). 05 Institute of Nano Science And Technology

5) Message from Prof Ashok K Ganguli: Founding Director, INST

On compleon of five-year term, I was relieved from this Instute on 02nd January, 2018 and is going to re-join my parent department viz. IIT- Delhi.

The Instute of Nano Science and Technology, Mohali was conceived by the Govt. of India as an instuon of educaon, training and research in Nano Science and Technology in India. I joined this youngest family of DST's instuons on 03rd January, 2013. I was associated this Instute during the last five years. My tenure of five years has been hugely evenul and of great significance to the development of specialized research facilies in the field of nanoscience and nanotechnology. I am quite happy that various objecves as envisioned and mandated for INST have been fulfilled to a large extent. With the hard work put-in by INST's faculty, officers and staff, the instute has aained a highly posive environment for encouraging outstanding research and academic development. I feel highly sasfied that we at INST has worked as a team and brought this instute on the forefront of research map at a fast pace during its inial five years. I am quite confident that the instute with its connued efforts will be a leading research instute in the area of nanoscience and nanotechnology recognized globally, where efforts in research will ulmately translate to society. While addressing the audience on the 5th Foundaon Day of INST, He said that “every achievement of INST, I celebrate and share with friends and colleagues Prof Ghosh felicitating Prof Ganguli elsewhere. Connue the good work, together, as interdisciplinary is the strength of INST. I am looking forward to the skyline changing with the buildings coming up rapidly”. And all of you having excellent campus in the near future and do not forget the great outreach program INST is known for. Wish you all the very best and thank you for being with me always and helping in making INST.

(Ashok Kumar Ganguli)

Shri P K Datta alongwith Prof Ghosh giving a plaque of INST's building to Prof Ganguli

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6) Research Facilies at INST: INST's Laboratories has high–end facilies like Microscopes, diffractrometers and Spectrophotometers: TEM, SEM, AFM, XRD, Confocal Raman, DLS, SAXS, CD, UV-vis-NIR HPLC, GC-MS, QPCR, Ultrafast spectroscopy, confocal microscopy with live cell imaging, ICP-MS, Nanoimprint lithography, PECVD, Electrochemical workstaon, BET Surface Analyser, TGA- DTA, Solar Simulator Rotavapor, Pepde Synthesizer, Protein Purificaon System, Autoclave (400 degC),Gel Documentaon System, Polymerase Chain Reactor, Biosafety Cabinet, High Performance Liquid Chromatography Probe Sonicator, Ultra Centrifuge etc. Some of the New Facilies Created are: a) Ultrafast Transient Broadband Spectrometer: Ultrafast Broad band transient absorpon spectrometer is located in Faraday Lab in Instute of Nano Science and Technology. The laser system is a Coherent regenerave amplifier (Astrella Ultrafast Ti:Sapphire Amplifier) (800 nm with repeon rate of 1 kHz and pulse duraon of <35 fs) seeded by a Ti:sapphire oscillator. The output of the amplifier was split into pump and probe beam lines. The output of the opcal parametric amplifier (OPerA-SOLO) was used as a pump source at the required wavelength (in the wavelength range of 350-1600 nm) and fed into the spectrometer through a synchronized chopper, thus generang 500 Hz sync signals. Quartz cells of 2 mm sample path length were used for transient absorpon studies.The data analysis was carried by Surface Xplorer soware. Kinec traces were obtained from me-resolved spectral data at appropriate wave-lengths. Major purpose of this instrument to monitor ultrafast charge carrier dynamics of solar energy conversion and photo- detector materials. Also excited state dynamics of organic and inorganic molecules to monitor ultrafast intra and inter-molecular electron and proton transfer reacon. b) Fluorescence Acvated Cell Sorng (FACS): The Flow Cytometry Facility is located in the Naonal Agri-food Biotechnology Instute (NABI), Mohali Laboratory of INST. This instrument (BD FACS Aria FUSION SORP) is having 5 lasers i.e. 488 nm Blue Laser, 640 nm Red Laser, 405 nm Violet Laser, 561nm Yellow Green Laser and 355 nm True UV laser having a life span of more than 3000 hours. The major purpose of this facility is for idenficaon and isolaon of various cell populaons using anbodies to which various colours or dyes are been aached and are directed at molecules known to exist on the cell surface or in the

07 Institute of Nano Science And Technology several colors aached to different anbodies, one can idenfy and purify cells that express any given configuraon of various molecules. c) Advanced Spectral Confocal Laser Scanning System: An advanced super resoluon confocal laser scanning laboratory is being created in INST-NABI laboratory. This is a very high end system capable of achieving high contrast and high resoluon imaging [can resolve structures of 120 nm (in x, y) and 350 nm (in z) in all X, Y and Z direcons. Besides carrying out regular confocal based imaging of samples in both fixed and live samples, the system also carries mul-photon and deep ssue imaging modules to gain detailed informaon from deep inside samples. d) High Performance Compung Cluster: A high-performing compung (HPC) cluster funded by SERB-DST has been installed at INST. The cluster consists of 15 Intel Xeon E5- 2650 compute nodes with one master node and100 Gbps intra node communicaons architecture. It has 140 Tb of RAID6 data storage capacity. Each node has 24 cores and 128 Gb of memory. The cluster is well equipped to perform highly parallel ab inio simulaons codes for condensed phase materials and bio- molecules. e) Nanoscale Physics and Device lab (NPDL): NPDL is located in the upcoming campus of INST dedicated to nanoscale physics and device fabricaon. NPDL is a host to many high end facilies varying from pre-fabricaon labs to characterizaon labs. The facilies here include Pulsed Laser Deposion system by Pascal for the fabricaon of epitaxial heterostructures. It is the first system to be installed in India for the temperature gradient and mul-target combinatorial growth of thin films. Electrical transport and magnec properes of the materials are characterized here by using Physical Property Measurement system by Quantum Design. It is a completely dry system having the temperature variability of 350 K to 1.8 K. The magnec field range of the system is 14 to -14 Tesla and is the second system in North India to have such high field range. The other facilies in NPDL includes e-beam evaporator by Excel Instruments. It is a combined system for thermal and e-beam evaporaon of metals. NPDL also houses Microfluidics reactor

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set up which is used for synthesis of nano-parcles using micron sized channels. The channels are fabricated using in-house technique with the help of Laser Engraver and 3D printer installed here.

Inauguration of NPDL lab by Bharat Ratna Prof. C. N. R. Rao

Visit of Prof. D. D. Sarma, IISc, Bangalore Pulse Laser Deposition System at NPDL

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7) Research at INST:

I. CHEMICAL BIOLOGY & THERAPEUTIC: 1). Dr. Deepa Ghosh, Scienst F and Group co-ordinator Research area of interest: Development of funconalized materials for ssue engineering applicaons With an aim to improve the ssue repair process, our group is Focusing on developing biomaterials that are funconalized to improve scaffold properes; opmize cell aachment, proliferaon and its differenaon; and increase cell migraon etc. We have recently developed nanocomposites of graphene oxide-hydroxyapate for addressing bone repair. Sponsored Project: Development of advanced third generaon matrix associated chondrocytes for carlage repair, DBT. 2). Dr. Surajit Karmakar, Scienst – E Research area of interest: Development of nano-therapeucs including screening of pepde and small molecule combinatorial therapy, siRNA delivery and pepde-mediated cancer therapy by targeng mitochondrial metabolism. Ÿ Understanding the molecular mechanisms of diabec renopathy and their prevenon by nanotherapy. Ÿ Nanomaterials for tumour imaging and chemo-photo combinaon therapy. To overcome resistance to chemotherapy, target validaon, signal transducon in membrane proteins and nanoparcles endocytoc cascade. Ÿ Receptor and ion channel regulaon on cell membrane organizaon, endosomal funcon and escape. Environment, Food and probioc Nano biotechnology. Fig: Lanthanum Carbonate Nanospheres (REM100) was synthesized via mix SDS/CTAB surfactant assisted synthesis. Crucial interacons of curcumin with REM100 endows with a characteriscs of fluorescent probe. The protein concentraon and c o n f o r m a o n b a s e d fl u o r e s c e n c e enhancement of Curcumin-REM100 10 Institute of Nano Science And Technology were observed by steady state fluorescence emission, Langmuir adsorpon and surface covering of the Curcumin-REM100. The steady state fluorescence anisotropy data affirm the formaon of protein-Curcumin-REM100 corona. The extent of Aβ interacon with Curcumin- REM100 demonstrang as promising probe could detect and delineate between monomer and aggregaon state of Aβ. Sensors and Actuators B: Chemical, 2018, 262, 687-695.

Publicaons (2017-18): Ø Srivastava AK, Dev A, Choudhury SR, Karmakar S. New Insight into Curcumin Tethered Lanthanum Carbonate Nanospheres and Protein Corona Conferring Fluorescence Enhancement based Sensive Detecon of Amyloid-beta Aggregates. Sensors and Actuators B: Chemical, 2018, 262, 687-695. Ø Singh PK, Srivastava AK, Dev A, Kaundal B, ChoudhurySR, Karmakar S.1,3β Glucan anchored, paclitaxel loaded chitosan nanocarrier endows enhanced hemocompability with efficient an-glioblastoma stem cells therapy. Carbohydr Polym., 2018, 180, 365-375. Ø Srivastava AK, Dev A, Karmakar S. Nanosensors and Nanobiosensors: Current trend and innovaon in perspecve of Food and Agriculture Sector. In Nanoscience in Food and Agriculture. Vol 5, 2017, 41-79. Ø Dev A, Srivastava AK and Karmakar S., Nanomaterial toxicity for plants. Environ Chem Le, 2017, 1-16. Ø Dev A, Srivastava A and Karmakar S. Nano-toxicity and Plants. In Nanoscience in Food and Agriculture. Vol 5, 2017, 169-204 (Springer Internaonal Publishing). Ø Yadav KS, Kumar Srivastava A, Dev A, Kaundal B, Roy Choudhury S, Karmakar S.Nanomelatonin triggers superior ancancer funconality in a human malignant glioblastoma cell line. Nanotechnology, 2017, 28, 365102. Ø Agrawal M, Yadav SK, Agrawal SK, Karmakar S. Nutraceucal phycocyanin nanoformulaon for efficient drug delivery of paclitaxel in human glioblastoma U87MG cell line. J Nanopart Res, 2017, 19, 272.

Sanconed projects: A high performance nanodelivery system for Inflammatory Bowel Disease (IBD) therapy, SERB; 2).Development of novel theranosc nanoplaorms for targeted therapy for liver cancers, for Proof of concept work, DST-Nano Mission.

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3. Dr. Md. Ehesan Ali, Scientist E Research Highlights: a). Chemical Bond-induced Spin-Cross over (SCO): The external-perturbaons or smuli act on the collecve molecular structures in the SCO process. However in this work, based on various ab inio computaons, Dr. Ali's group showed that the manipulaon on a single cobalt-phosphorous chemical bond can control the

molecular ground spin-state of the penta-coordinated Co(II)-complex. Thealso observed that the single-ion magnec (SIM) properes could also simultaneously be altered along with SCO. Thus targeng a specific chemical bond to alter the molecular ground spin-state paves a new avenue to control the molecular magnesm. b). Strong Long-range Exchange Interacons Mediated Through Polyacene Couplers: Applying mul-reference calculaons that accounts both dynamical as well as non-dynamical electronic correlaons,the magnec exchange interacons for the long-range spacers were computed. It is found to be quite strong and independent of the lengths of the coupler. Such long-range exchange interacons could be aributed to the enhanced-conjugaon, as it

opened up mulple conductance channels that facilitate the orbital assisted tunneling currents. The spin-spin interacons between the radical center and the tunnelingelectron escalate the long-range exchange interacons. The observed mechanism is similar to the Ruderman-Kile-Kasuya-Yosida (RKKY) type interacons, in which the long-range exchange interacons occurs via the coupling of localized spins with the spins of the conducng electrons in metallic substrates. In absence of the conducon electron in organic diradicals, the molecular conductance (G) that occurs via the electron tunneling phenomenon play an instrumental role in mediang the long-range exchange interacons. 12 Institute of Nano Science And Technology c). Ion and small molecule transportaon through the open pore allows the transmembrane cell communicaons and also supplies nutrients for the biochemical acvies in cells. In this project, we invesgated such ion dynamics applying ab inio calculaons and molecular dynamics simulaons. The dynamic nature of the electrostac potenal of the pore that

selecvely controls ion transportaons in different Pdu shell-proteins have been confirmed along with various state-of-the-art experiments in collaboraon with Dr. Sinha.

Publicaons:

Ø Kathewad, N.; Pal, S.; Kumawat, R. L.; Ali, Md. E.; Khan, S. Synthec Diversity and Luminescence Properes of ArN(PPh 2) 2-Based Copper(I) Complexes Eur. J. Inorg. Chem2018, 2518. Ø Jiang,X.; Futera, Z.; Ali, Md. E.; Gajdos,F.; von Rudorff, GF.; Carof, A. Breuer, M. Blumberger, J.Cysteine Linkages Accelerate Electron Flow through Tetra-Heme Protein STC.J. Am. Chem. Soc.2017, 139, 17237. Ø Girovsky, J.;Nowakowski, J.; Ali, Md. E., Baljozovic, M.; Rossmann, Harald R.; Nijs, T.; Aeby, E. A.; Nowakowska, S.; Siewert, D.; Srivastava, G.; Wäckerlin, C.; Dreiser, J.; Decurns, S.; Liu, S.-X.; Oppeneer, P. M.; Jung T. A. Ballav, N. Long-range ferrimagnec order in a two- dimensional supramolecular Kondo lace.Nat. Commun. 2017, 8, 15388. Ø Madhuri, K. P.; Kaur, P., Ali, Md. E.,John N. S.Nanoscale Conductance in Lead Phthalocyanine Thin Films: Influence of Molecular Packing and Humidity.J. Phys. Chem. C, 2017, 121, 9249.

Sanconed projects: 1. SERB-ECR: “Photo-magnec Control of Molecular Spintronic Properes” 2. DST-VR (Indo-Swedish bilateral Proposal) “In Silico Studies of Magnec and Vibraonal Properes of Porphyrins for Diagnosc Applicaons “

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4). Dr. Sharmistha Sinha, Scienst E

Research area of interest: The main research theme of our laboratory is protein structure- funcon relaonship applied to protein nanostructure paradigms and naturally occurring biomaterials. The main protein structures we are interested in are bacterial microcompartments and amyloid aggregates. Bacterial microcompartments (BMCs) are huge, polyhedral shaped all protein structures found in many bacteria. Inside the BMCs, there are specific enzymes that carry on a biological process and these enzymes are surrounded by an envelope of protein sheet. We are trying to explore and understand the properes of the polyhedral shell and exploit them for different real life uses. Our research on amyloid structures focuses on understanding mechanism of amyloid formaon and idenfying the process variables for development of therapeucs. We further aim to design and formulate these pepde inhibitors into biocompable nanostructures for enhanced bioabsorpon, slow release and beer targeng. Our laboratory is also working on biochemical and genec manipulaon of bacterial cellulose producon to enhance quality and yield of cellulose.

Publicaons:

Ø Cellulose-Metallothionein Matrix for Metal Binding. NK Bari, S Barua, A Garg, MK Sannigrahi, S Sinha. Carb. Pol. 192(15), 126-134, 2018

Ø Enhanced bacterial cellulose producon from Gluconobacter xylinus using super opmal broth PT Chandrasekaran, NK Bari, S Sinha, Cellulose 24 (10), 4367-4381, 2017 Patent filed: Cellulose-Metallothionein Conjugate for Metal Binding. Applicaon No.: 201711034498, Date of Filing: 28th September, 2017, Inventor(s): 1) Sharmistha Sinha 2) Naimat Kalim Bari 3) Shaswat Barua 4) Ankush Garg Award: SERB women excellence award

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5) Dr. Rahul Kumar Verma,Scienst D Research area of interest: My research involves designing, development and evaluaon of novel targeted & controlled release drug delivery systems for pharmaceucal, herbal, biomaterial and nanomedicine applicaons, which can be administered by convenonal and unconvenonal non-invasive routes. Currently working on various modalies i.e. development of novel formulaon (Nano-in Micro) for controlled delivery of pepde in lungs using Trojan horse approach; Novel nano-formulaon for cold injury; pulmonary delivery of fixed dose combinaon for High Altude Pulmonary Edema and Enzyme acvated targeted nano-formulaons of autophagy/apoptosis-inducing bioacve for drug resistant lung cancer.

Pulmonary & Nasal Delivery Transdermal Delivery Intra-arcular Delivery

Figure:Designing and development of pulmonary delivery of nanoparcles and microparcles for tuberculosis and lung cancer. Designing nano spray gel formulaon for cold injury in high altute regions. Development of smuli triggered nanoformulaons for intra-artcular delivery for rheumatoid arthris.

Publicaons (2017-18): Ø Sharma A, Vaghasiya K, Ray E, Verma RK* (2018) Nanoencapsulated HHC10host defense pepde(HDP) reduces the growth of E.coli via mulmodal mechanism Arficial Cell, Nanomedicine and Biotechnology ( accepted) Ø Sharma A, Vaghasiya K, Gupta P, Gupta UD, Verma RK*Reclaiming hijacked phagosomes: Hybrid nano-in-micro encapsulated MIAP pepde ensures host directed therapy by specifically augmenng phagosome-maturaon and apoptosis in TB infected macrophage cells Internaonal Journal of Pharmaceucs. 2018 Nov 24;536(1):50-62 Ø Sharma A, Vaghasiya K, Ray E, Verma RK* (2018) Lysosomal targeng strategies for design and delivery of bioacve for therapeuc intervenons Journal of Drug Targeng2018 Vol 26, NO. 3, 208–221

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Ø Malik R, Tondwal S, Venkatesh K.S, Gupta G, Shanker K, Verma RK and Misra A Timing feedback-inhibion of the reproducve hormone axis for male contracepon Molecular Medicine : Bench to Bedside and Beyond (Indian Society for the Study of Reproducon and Ferlity) 2018, 117-130. Ø Sharma A, Verma RK* (2017) Hybrid Nano-in-Micro systems for lung delivery of Host Defence Pepdes (HDP) as adjunct therapeucs for Pulmonary TB. Drug Delivery to Lungs (Proceedings) Vol 26, 3, 113–115.

6). Dr. Priyanka, Scienst D Research area of interest: Nanobioprobe based low cost Apta/Immuno-diagnosis for clinical diagnosis (cardiac markers: Myoglobin, Troponin I, BNP, FABP; cancer markers: Prostate; Bacterial Pathogens: E. coli, Salmonella typhi, Mycobacterium tuberculosis), sepsis & thyroid management and environmental monitoring applicaons (Pescides, explosives, drugs, toxins, dyes, VOCs). Ø Sensor design, fabricaon, tesng and validaon with real samples. Ø Microfluidics devices based sensive assay plaorms for disease management. Ø Aptamer tethered DNA nanocarriers for targeted drug delivery in therapeucs and diagnoscs applicaons.

Publicaons: Ø Shorie, M.; Kumar, V.; Kaur, H.; Singh, K.; Tomer, V.K.; Sabherwal, P .Plasmonic DNA hotspots made from tungsten disulfide nanosheets and gold nanoparcles for ultrasensive aptamer-based SERS detecon of myoglobin. Microchimica Acta. 2018, doi.org/10.1007/s00604-018-2705-x Ø Kaur, H.; Shorie, M.; Sharma, M.; Ganguli, A.K.; Sabherwal, P .Bridged Rebar Graphene funconalized aptasensor for pathogenic E. coli O78: K80: H11 detecon. Biosens Bioelec. 2017, 98, 486-493. Ø Tomer, V.K.; Singh, K.; Kaur, H.; Shorie, M.; Sabherwal P .Rapid Acetone Detecon using Indium loaded WO3/SnO2 Nanohybrid Sensor. Sensors & Actuators B. 2017, 253, 703-713.

Award/ recognion: INSA vising Fellowship 2017; INST Naonal Technology day Award 2017 Sponsored projects: Low cost diagnosc system for public health surveillance, targeng bacterial enteric pathogens.(~3 crores), DST Nano Mission

Technology Developed/being Developed : i) Smart phone based device for detecng cardiac markers; ii) Device based on Flagellin (FliC/FljB) pepdes for the specific detecon of Salmonellosis for detecng Salmonellosis

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Patent filed: “Flagellin (FliC/FljB) pepdes for the specific detecon of Salmonellosis: a new method and a device thereof” Inventors: Parveen Rishi, Chander Raman Suri, Priyanka Sabherwal, Pree Pathania, Harmanjit Kaur T.I.(01)/TIFA/2018

7).Dr. Jiban Jyo Panda, Scienst C Our group is presently working on three major projects. First is the development of biocompable, parcularly pepde and pepde hybrid based nanostructures for effecve drug delivery across physiological barriers such as blood brain and blood ocular barriers (Figure 1). In this project,We have acquired some preliminary data such as development of various vesicular and tubular pepde based nanostructures with inherent propensity to cross the blood brain barrier. The nanostructures were characterized using dynamic light scaering, electron microscopy (transmission electron microscopy, scanning electron microscopy) and light microscopy. BBB barrier penetraon has also been assessed using PAMPA assay and some nanostructures have been found to cross this in vitro model.

Figure 1: Development of pepde based nanocarrier systems for delivery across the blood brain barrier.

Our group is also working in another project which is an Inspire Faculty Fellow project. In this project, aim is to develop versale, mulfunconal and adaptable pepde nanofiber scaffolds for promong neuritogenesis in brain injury (Figure 2). Chasing this aim, we have started developing pepde nanofibers and have characterized them using light microscopy, electron microscopy, light scaering, rheology etc.

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The fiber properes have been shown to vary based on their assembling condions. Further cell based studies are in progress in this direcon.

Figure 2: Peptide based brous scaffolds for neural tissue engineering applications.

In another project my group is trying to develop pepde nanocarriers towards potenal applicaons in the field of smuli responsive drug delivery (Figure 3). We are also trying to develop biocompable and topical Nano therapeucs for potenal cataract therapy.

Publicaons: (2017-18) Ø Singh, P. K.; Chibh, S.; Dube, T.; Chauhan, V. S.; Panda, J. J.; Arginine-α, β-ehydrophenylalanine Dipepde Nanoparcles for pH-Responsive Drug Delivery. Pharm Res. 2018,16, 35. Ø Kumar, V.; Kaur, J.; Singh, A. P.; Singh, V.; Bisht, A.; Panda, J. J.; PHISTc protein family members localize to different subcellular organelles and bind Plasmodium falciparum major virulence factor PfEMP-1. Mishra PC, Hora R. FEBS J. 2018, 285, 294-312. Ø Varshney, A.; Panda, J. J.; Singh, A. K.; Yadav, N.; Bihari, C.; Biswas, S.; Sarin, S. K.; Chauhan, V. S. Targeted delivery of microRNA-199a-3p using Figure 3: Peptide Nanoparticles for self-assembled dipepde nanoparcles stimuli responsive drug delivery. efficiently reduces hepatocellular carcinoma in mice. Hepatology. 2018; 67; 1392-1407. Ø Dube, T.; Chibh, S.; Mishra, J.; Panda, J. J. Receptor Targeted Polymeric Nanostructures Capable of Navigang across the Blood-Brain Barrier for Effecve Delivery of Neural Therapeucs. ACS Chem Neurosci. 2017,18, 2105-2117. Ø Baskar, G.; Ravi, M.; Panda, J. J.; Khatri, A.; Dev, B.; Santosham, R.; Sathiya, S.; Babu, C. S.; Chauhan, V. S.; Rayala, S. K.; Venkatraman, G. Efficacy of Dipepde-Coated Magnec Nanoparcles in Lung Cancer Models Under Pulsed Electromagnec Field. Cancer Invest. 2017, 35, 431-442. Ø Dube, T.; Mandal, S.; Panda, J. J. Nanoparcles generated from a tryptophan derivave: physical characterizaon and an-cancer drug delivery. Amino Acids. 2017, 49, 975-993.

Sponsored projects: Mulmodal Glioblastoma Therapy by Blood Brain Barrier Traversing and Glioma Targeng An-cancer Pepde Theranosc Nanoparcles; DBT: Development of Versale, Mulfunconal and Adaptable Pepde Nanofiber Scaffolds with Potenal for Promong Neuritogenesis in Brain Injury. DST-INSPIRE. 18 Institute of Nano Science And Technology

8). Dr. Manish Singh, Scienst C Research area of interest: My group research is focused on Nanotoxicology, Developmental Nanotoxicology, In utero Exposures and CNS Development, Neuro-Behavioral Analysis, Nanoneurotoxicology, Nano Environmental Health and Safety, and Bio imaging Tools (Confocal and Electron Microscopy)

Ø The indiscriminate usages of nanotechnology can deteriorate the living condions for humans through exposures to the various hazardous nanomaterials whether incidental or deliberate. Ø Despite several years of research, definive findings regarding the extent of toxicological risks arising from using CNMs are not well-established. Sll, the database on toxicity of engineered NMs is to date very limited.The use of CNTs and Graphene NMs in the targeted drug delivery and, other biomedical and agricultural applicaons are important but considering the likelihood of exposure to human being and its toxic effects are yet not well-established, thus it becomes necessary to evaluate the toxicity of these NMs. Ø These findings can also be significant for the development of carbonaceous nanomaterials-based drug delivery system and other biomedical applicaons in future.

Fig:In this study we tagged the GO with ICG, a fluorescent dye and explored the short term Bio distribuon in rat model using in-vivo imaging system (IVIS). Results showed the accumulaon of GO in liver. We further explored for the toxicity of GO in long term repeated dose toxicity studies which showed increased levels of LPO, ROS, SOD & catalase acvies along with the alteraons in Liver histology suggesng the hepatotoxic effects of GO exposure.

Publicaons Ø Khushboo Soni, Sushil Kumar, Riyajuddin , Kasinath Ojha, Manish Singh, Kaushik Ghosh, Vercally Aligned Core-Shell p-i-n Silicon Nanowire Array and N-Doped Graphene Quantum Dots Heterostructure for Photoelectrochemical Hydrogen Evoluon. ACS Applied Materials & Interfaces (Communicated: am-2018-060652)

Sanconed projects (Ongoing): II).Assessment of maternal, reproducve and fetal toxicity induced by intrauterine exposure of carbonaceous nanomaterials like graphene and carbon nanotubes. SERB (DST). ii).Glioma Targeng Ancancer Pepde Theranosc Nanoparcles. DBT Biocare.

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9) Dr. Subhasree Roy Choudhury, Scienst C Research area of interest: Development of target specific nanotherapeucs for epigenec regulaon of cancer. Chemoprevenon and mechanism of acon of drug/siRNA loaded nanoparcle mediated therapy for leukemia, neuroblastoma and glioblastoma. New drug development from natural products and combinaon therapy against cancer. Development and applicaon of high-throughput funconal gene-based screening for cancer. Mulple retrovirus and lenvirus mediated gene delivery for target validaon and funconal implicaon in cancer. A novel nutraceucal based highly biocompable drug-delivery system has been developed that shows an excellent an-cancer efficacy in the oral squamous cell carcinoma cell line model in both 2D in vitro and 3D mul-layer ex vivo ra models. Present nano nutraceucal showed G0/G1 phase cell cycle arrest within 48 hrs of treatment, caused downregulaon of Polycomb group of proteins EzH2 and Bmi-1 expressions, also resulted in increased apoptosis through elevated level of caspase-3. Thus the present Nano formulaon has potenal for improved drug delivery in oral cancer ssues and shows promise for potent ancancer acvity. Publicaons: Ø New Insight into Curcumin Tethered Lanthanum Carbonate Nanospheres and Protein Corona Conferring Fluorescence Enhancement based Sensive Detecon of Amyloid-beta Aggregates. Srivastava AK, Dev A, Choudhury SR, Karmakar S. Sensors and Actuators B: Chemical, 2018, 262, 687-695. Ø Singh PK, Srivastava AK, Dev A, Kaundal B, Choudhury SR*, Karmakar S. 1,3β Glucan anchored, paclitaxel loaded chitosan nanocarrier endows enhanced hemocompability with efficient an-glioblastoma stem cells therapy. Carbohydr Polym. 2018,180, 365-375. Ø Sardoiwala MN, Kaundal B, Choudhury SR*. Toxic impact of nanomaterials onmicrobes, plants and animals. Environ Chem Le, 2018, 16,147-160. Ø Kumar Yadav S, Kumar Srivastava A, Dev A, Kaundal B, Roy Choudhury S, Karmakar S. Nanomelatonin triggers superior ancancer funconality in a human malignant glioblastoma cell line. Nanotechnology, 2017, 28, 365102. Ø Kaundal B, Dalai S and Choudhury SR*. Nanomaterial toxicity in Microbes, Plants and Animals. Nanoscience in Food and Agriculture, (Springer Nature publisher) 2017, 5, 243- 266.

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Ø Sardoiwala MN, Kaundal B, Choudhury SR*. Development of engineered nanoparcles expeding diagnosc and therapeuc applicaons across blood brain barrier, Handbook of Nanomaterials for Industrial Applicaons, Elsevier Press 2018.

Sanconed projects: Project 1: Nanotherapy for controlling epigenec regulaon by polycomb in Myb mediated leukemia, Funding agencies DBT. Project 2: Idenficaon of Polycomb and c- Myb signaling and their targeted nanotherapy in leukemogenesis, funding agencies DST

10) Dr. Asihan Shanavas, Scienst C Research area of interest: 1) Targeted combinatorial nanomedicines: Cancer paents undergo vigorous combinaon chemotherapeuc protocols. Due to variaons in pharmacokinecs, membrane transport and biodistribuon properes of different chemotherapeucs, dosage and opmizaon of drug scheduling become highly difficult. Combinaon nanomedicines offer vehicle uniformity, raometric drug loading with temporal site-specific release of the drugs. Our group invesgates polymeric core-shell nanoparcles for compartmentalizaon and sequenal release of two or more chemotherapeucs. 2) Organo-Inorganic Biomaterials for Theranoscs: Mulfunconal biomaterials offer a 'One for All' approach towards precise in vivo detecon and subsequent treatment of solid tumors. Our group invesgates organo-inorganic composite biomaterials for simultaneous therapy and imaging of cancerous ssues. 3) Plasmonic nanomaterials for Photothermal Therapy: Cancer drug resistance is an evolving paradigm that is interconnected with a multude of signaling pathways regulang cell survival, growth and proliferaon. Gold based anisotropic nanostructures such as nanoshells have shown a huge success in combang resistant tumors. With beer engineering of these nanoshells, a new generaon of nanomedicines may emerge that can effecvely combat undruggable advanced cancers. Our group explores such an arena, where asymmetric plasmonic nanoparcles will be systemacally explored for photothermal therapy against drug-resistant cancers, Shanavas A, et al. Int J Biol Macromol. 2018, 110:392-398. A simple technique to synthesize mulfunconal nanoparcles without compromising on any of their funconality is a challenge. We have aempted to opmize a two-step procedure of gold coated polymeric template involving 1) Single pot synthesis of PLGA nanoparcles with caonic surface charge using glycol chitosan and 2) in situ gold coang for formaon of gold coated PLGA nanoshell (AuPLGA-NS).

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These gold-coated PLGA nanoparcles were explored for photothermal therapy (PTT) and as X- ray/CT contrast agents. Biocompability and photothermal cytotoxicity of AuPLGA-NS were evaluated in-vitro and results confirmed the therapeuc efficacy of these parcles resulng in 80% cancer cell death. Besides, it also showed potenal X-ray/CT imaging ability with contrast equivalent to that of Iodine. The results demonstrated that these gold-coated PLGA nanoparcles synthesized by a simple approach could be used as a mulfunconal nanosystem for cancer theranoscs.”

Publicaons: Ø P Yadav, S P Singh, A K Rengan, R Srivastava, A Shanavas*, Gold laced bio-macromolecules for theranosc applicaon, Int. J. Biol. Macromol, 110, 2018, 39-53. Ø Glycol chitosan assisted in situ reducon of gold on polymeric template for an-cancer theranoscs, A Shanavas*, A K Rengan, D Chauhan, L George, M Vats, N Kaur, P Yadav, P Mathur, S Chakraborty, A Tejaswini, A De, R Srivastava, Int. J. Biol. Macromol, 110, 2018, 392-398. Ø K Naim, S T Nair, P Yadav, A Shanavas, P P Neelakandan, Supramolecular confinement within chitosan nanocomposites enhance singlet oxygen generaon, ChemPlusChem, March 2018, Just accepted arcle.

Award/Recognion: Indo-Australian Career Boosng Gold Fellowship from DBT for 2016-17 Sanconed projects: Gold Capsuled Combinaon Nanomedicine for Target Specific Therapy of Chemo resistant Breast Tumors:SERB-EMR scheme (as PI) ;Reconstutable Lyophilized Plasmonic Semishells as Near Infra-Red Photo thermal Nanotransducers for Cancer Treatment: DBT Nanobiotechnology scheme (as PI).

11) Dr. Shyam Lal M, Scienst B Research area of interest:Development of Modified lipid nanovesicles based oral drug delivery system for the treatment of visceral leishmaniasi; Development of Solid lipid nanoparcles mediated drug delivery of anepilepc drugs; Development of Efficient per oral delivery system of Amphotericin B using surface modified Vitamin B 12.

Research Highlights: Our group works at the interface of nanoscience and infecous biology. We aim to develop lipid based nanoparculate system for oral delivery of amphoteric drugs through nanomodificaons. In hyper endemic areas of Bihar, India, Amphotericin B (AmB) is currently the first-line parenteral treatment for Visceral Leishmaniasis (VL). However, prolonged duraon, adverse reacons, and the need to monitor renal funcon and electrolyte levels remain well-recognized drawbacks of AmB treatment. Lipid formulaons of AmB have been developed in order to improve its bioavailability and pharmacokinec properes,

22 Institute of Nano Science And Technology considerably reducing side effects. The liposomal formulaon (AmBisome) is an approved treatment for VL in India that besides the reduced toxicity has a beer half-life and a high level of efficacy, with 90% cure rate. The main limitaons are its high cost, administraon route and lack of stability at high temperature (cold chain is needed). Miltefosine was recently approved for VL treatment in India but this is also posing serious concerns with regard to its teratogenic effect. In this perspecve, oral administraon of AmB is being widely considered as a realisc soluon, since it has the potenal to eliminate acute toxicity associated with parenteral delivery, to reduce and control sub-acute side effects (renal toxicity), to decrease substanally the associated costs of the treatment, to improve the quality of life for paents and to allow therapy to reach developing naons. Currently we are developing surface modified lipid vesicles/ solid lipid nanoparcles mediated therapeucs for Visceral Leishmaniasis.

Publicaons:Mannose-conjugated curcumin-chitosan nanoparcles: Efficacy and toxicity assessments against Leishmania donovani, Pramila Chaubey, Brahmeshwar Mishra, Shyam Lal Mudavath, Ravi R Patel, Sundeep Chaurasia, Shyam Sundar, Vasan Suvarna, Marvis Monteiro, Int J Biol Macromol. 2018 May; 111:109-120. Sanconed Projects: Development of modified lipid nanovesicles based oral drug delivery system for the treatment of visceral leishmaniasis.

12) Dr. Rehan Khan, Scienst B Research area of interest: Synthec lethality is a molecular-targeted therapy for selecve killing of cancer cells. We exploited a lethal interacon between superoxide dismutase 1 inhibion and Bloom syndrome gene product (BLM) defect for the treatment of colorectal cancer (CRC) cells (HCT 116) with a customized lung cancer screen-1-loaded nanocarrier (LCS-1-NC). The drug LCS-1 has poor aqueous solubility. To overcome its limitaons, a customized NC, composed of a magnete core coated with three polymeric shells, namely, aminocellulose (AC), branched poly(amidoamine), and paraben-PEG, was developed for encapsulang LCS-1. LCS-1-loaded Nano carrier (LCS-1-NC) demonstrated high killing selecvity (104 mes) toward BLM-deficient HCT 116 cells over BLM-proficient HCT 116 cells. Due to enhanced efficacy of the drug using Nano carrier, the sensivity difference for BLM-deficient cells increased to 1.7 mes in comparison to that with free LCS-1. LCS-1-NC induced persistent DNA damage and apoptosis, which demonstrates that LCS-1-NC effecvely and preferenally killed BLM-deficient CRC cells.

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Publicaons Ø Gupta, A.; Ahmad, A.; Dar, A.I.; Khan, R. Synthec lethality: From Research to Precision Cancer Nanomedicine. Current Cancer Drug Targets 2018, 18 (4), 337 – 346. Ø Gupta, A.; Ahmad, A.; Singh, H.; Kaur, S.; K, M. N.; Ansari, M.M.; Jayamurugan, G.; Khan, R. Nano carrier Composed of Magnete Core Coated with Three Polymeric Shells Mediates LCS-1 Delivery for Synthec Lethal Therapy of BLM-Defecve Colorectal Cancer Cells. Bio macromolecules 2018, 19 (3), 803−815. Sanconed projects: Dual-Drug loaded Customized Nanocarrier for Synergisc Synthec Lethal Killing of Colorectal Cancer, Funding Agency: DST-Nano Mission.

13) Dr. Deepika Sharma, Scienst B Our group research interest lies at the interface of engineering, medicine and biology to develop novel plaorms for understanding, diagnosing and treang human disease. Specifically, my work is focused on diagnoscs and treatments for cancer. My group research work is centred on designing and development of targeted nanoparcles to perform complex task such as mulmodal, non-invasive tumour imaging; trigger the release of a targeted, therapeuc payload, hyperthermia and mulfunconal agents for cancer therapies. Our lab works on the synthesis of magnec materials from both chemical and natural pathways. Magnetotacc bacteria, a group of aquac prokaryotes are being used as a natural source to isolate magnetosomes through various cell disrupon techniques. Magnetosomes are tested for their ability to act as nano-sized biocompable magnec heaters. The magnec materials generated are extensively characterized and evaluated for their potenal to be used in magnec hyperthermia-mediated cancer therapy, primarily for glioblastoma mulforme (GBM) at the pre-clinical level. We also study the comparison of characteriscs of chemically and naturally synthesized magnec nano-parcles to be used in hyperthermic applicaons. The primary research area in our lab is to invesgate the capability of these magnec materials to cross the blood-brain barrier which is one of the major challenges to treat gliomas. Also, we are working to evaluate the capacity of hyperthermia to enhance the chemotherapeuc effect of temozolomide for GBM when used as combinaon therapy. In addion to GBM, the magnec nano-heaters synthesized in the lab will also be evaluated for their therapeuc effect for other solid tumors like breast cancer. Sanconed projects: “Temozolomide delivery across blood-brain barrier through Nanomagnec Transducer: A Targeted Therapy for Glioblastoma Mulforme”funded by 'DST- SERB'.

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II. NANOSTRUCTURED DEVICES

1) Prof. Hirendra Nath Ghosh, Scienst G (Group Coordinator)

Correlang Charge Carrier Dynamics with Efficiency in Quantum Dot Solar Cells to find the role of Excitonics to Design and Development of Highly Efficient Devices: The photovoltaic performance of quantum dot solar cells strongly depends on the charge carrier relaxaon and recombinaon processes, which need to be modulated in a favourable way to obtain maximum efficiency. Recently, we have significantly devoted our efforts to invesgate the carrier dynamics of nanocrystal sensizers both in soluon phase and upon deposited on TiO2 photoanode with the aim to correlate the excitonics with solar energy conversion efficiency. In this mini-review we summarize some proof-of-the concepts that efficiency can be directly correlated with the exciton dynamics for quantum dot solar cells. Our findings are based on CdSeS alloy, CdSe/CdS core/shell, Au/CdSe nano-hybrids and Mn-doped CdZnSSe nanocrystals where we opmize the favourable excitonic processes to enhance the efficiency. We have demonstrated the prospects and limitaons that need to be addressed in future.

Selecve Publicaons in 2017-18:

Ø Tushar Debnath, Kausturi Parui,Sourav Mai, and Hirendra N. Ghosh*, An Insight into the Interface through Excited-State Carrier Dynamics for Promising Enhancement of Power Conversion Efficiency in a Mn-Doped CdZnSSe Gradient Alloy,Chem. Eur. J.,2017, 23, 3755- 3763. Ø Tushar Debnath, D Sebasan, Sourav Mai, and Hirendra N. Ghosh*, Tuning Hole and Electron Transfer from Photo-excited CdSe Quantum Dot to Phenol Derivaves: Effect of Electron Donang and Withdrawing Moiety, Chem. Eur. J.,2017, 23, 7306-7314. Ø Jayanta Dana, Tushar Debnath and Hirendra N.Ghosh*, Hot-Electron Transfer from Semiconductor Domain to Metal Domain in CdSe@CdS{Au} Nano-Heterostructure, Nanoscale 2017, 9, 9723 – 9731. Ø Pallavi Singhal, Partha Maity,Sanjay K. JhaandHirendra N. Ghosh*Metal-Ligand Complex Induced Ultrafast Charge Carrier Relaxaon and Charge Transfer Dynamics in CdX (X = S, Se, Te) Quantum Dots Sensized Nitro Catechol, Chem. Euro. J.,2017, 23, 10590-10596.

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Ø Pallavi Singhal, Sanjay K. Jha, BalGovind Vats, and Hirendra N. Ghosh*,.Electron Transfer Mediated Trace Level Detecon of Uranium Using CdSe/CdS Quasi Type II Core Shell Quantum Dots: An Insight Mechanisc Studies, Langmuir, 2017, 33, 8114–8122. Ø , and Hirendra N. Ghosh* , Carrier Relaxaon Dynamics in Type-II ZnO/CdSe Quantum Dot Heterostructure, Phys. Chem. Chem. Phys., 2017, 19, 24896- 24902. Ø S. Mai, J. Dana, Y. Jadhav, T. Debnath, S. K. Haram, and H. N. Ghosh*, Electrochemical Evaluaon of Dopant Energecs and the Modulaon of Ultrafast Carrier Dynamics in Cu-Doped CdSe Nanocrystals, J. Phys. Chem. C.,2017, 121, 27233-27240. Ø S.Mai, F. Azlan, P. Anand, Y. Jadhav, J. Dana, S. K. Haram and H. N. Ghosh*, Boosng the Efficiency of Quantum Dot Solar Cells Through Formaon of Caon Exchanged Hole Transporng Layer, Langmuir, 2018, 34, 50–57. Ø J. Dana, P. Anand, S. Mai, F. Azlan, Y. Jadhav, S.K. Haram, H. N. Ghosh*, Inhibing Interfacial Charge Recombinaon for Boosng Power Conversion Efficiency in CdSe{Au} Nanohybrid Sensized Solar Cell, J. Phys. Chem. C, 2018, 122, 13277−13284. Ø J. Dana, S. Mai, V. S. Tripathi. and Hirendra N. Ghosh*, Direct Correlaon of Excitonics with Efficiency in Core Shell Quantum Dot Solar Cell, Chem. Eur. J., 2018, 24, 2418–2425. Ø J. Dana, P. Maity, B. Jana, S. Mai,and Hirendra N. Ghosh*, Concurrent Ultrafast Electron and Hole Transfer Dynamics in CsPbBr3 Perovskite and Quantum Dots, ACS Omega, 2018, 3, 2706-2714. Ø T. Debnath, K. Parui, S. Mai, H. N. Ghosh*, Unique Solar Conversion Efficiency Performance of High Temperature Gradient Alloy over Low Temperature One: Comprehending Interfaces through Excitonics Study, J. Phys. Chem. C, 2018,122, 11312−11321. Ø S. Mai, J. Dana, and Hirendra N. Ghosh*Correlang Charge Carrier Dynamics with Efficiency in Quantum Dot Solar Cells: Can Excitonics Lead to Highly Efficient Devices? Chem. Eur. J., 2018, (Mini Review) (ASAP) MS No: chem.201801853 Ø Pallavi Singhal, and Hirendra N. Hot Charge Carrier Extracon from Semiconductor Quantum Dots: A Step toward High Efficiency Quantum Dot Solar Cell. J. Phys. Chem. C, (Feature Arcle) 2018, ASAP, MS No: acs.jpcc.8b03980.

2) Dr. Suvankar Chakraverty, Scienst E

Oxide Thin films, Interface and Supper laces:Designing and understanding the physical properes of new oxide materials with integrated funconalies for spin- electronics devices in the form of thin films, super-lace and interfaces with atomic scale control and monitoring

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We are also involved in tuning the topology and physical properes of maer through strong spin-orbit coupling and broken symmetries. We have set up a state of art laboratory equipped with combinatorial pulsed laser MBE, 14T (1.8 – 300K) physical properes (magnec and electrical) measurement systems, wire-bonder and metal electrode (E-beam) deposion system (DST Funded)

Publicaons: Ø Gaikwad, V. M.; Goyal, S.; Yanda, P.; Sundaresan, A.; Chakraverty, S.; Ganguli, A. K.” Influence of Fe substuon on structural and magnec features of BiMn2O5 nanostructures”. J. Magn. Magn. Mater., 2018, 452, 120-128. Ø Wadehra, N.; Tomar, R.; Haider, S.; Sharma, M.; Singh, I.; Jena, N.; Prakash, B.; Sarkar, A. D.; Bera, C.; Venkatesan, A.; Chakraverty, S.”Electronic structure modificaon of the KTaO3 single crystal surface by Ar+ bombardment”. Phys. Rev. B., 2017, 96(11), 115423(1-6). Ø Tomar, R.; Wadehra, N.; Budhiraja, V.; Prakash, B.; Chakraverty, S. “Realizaon of single terminated surface of perovskite oxide single crystals and their band profile (LaAlO3)0.3(Sr2AlTaO6)0.7, SrTiO3 and KTaO3 case study”. Appl. Surf. Sci., 2017,427, 861- 866. Ø Balal, M.; Sanwlani, S.; Wadehra, N.; Chakraverty, S.; Sheet, G. “Electrical domain wring and nanoscale potenal modulaon on LaVO3/SrTiO3”. Appl. Phys. Le., 2017, 110,261604(1-5). Ø Kaur, P.; Chakraverty, S.; Ganguli, A.K.; Bera, C. “High anisotropic thermoelectric effect in palladium phosphide sulphide”. Phys. Status Solidi B, 2017, 1-5. Ø Wadhera, N.; Gupta, N.; Prakash, B.; Sharma, D.; Chakraverty, S. “Biocompable ferrite nanoparcles for hyperthermia: effect of polydispersity, anisotropy energy and inter- parcle interacon”. Mater. Res. Le., 2017, 4(2), 025037(1-6).

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3) Dr. Dipankar Mandal, Scienst E Research area of interest: I joined this instute as a Scienst – E on 01/1/2017. My Research Interest are Piezo, Pyro & Ferroelectric Materials, Mechanical and Thermal Energy Harvesters (Nano generators), Self-powered Electronics, Bio-signal monitoring via Non-invasive Biosensor and e-Skin.

Schemac: Thermal and mechanical energy harvesng by flexible ferroelectric nanocomposite (SEM image), where wrist pulse rate is recorded via piezoelectric phenomena and output current generaon via pyro-electric phenomena is illustrated.

Publicaons:

Ø A. Sultana, Md. M. Alam, T. R. Middya and D. Mandal*, 2018, A pyroelectric generator as a self-powered temperature sensor for sustainable thermal energy harvesng from waste heat and human body heat, Applied Energy 221, 299 – 307. Ø A. Sultana, P. Sadhukhan, Md. M. M. Alam, S. Das, T. R. Middya and D. Mandal*, 2018, Organo-Lead Halide Perovskite Induced Electroacve β-Phase in Porous PVDF Films: An Excellent Material for Photoacve Piezoelectric Energy Harvester and Photodetector, ACS Appl. Mater. Interfaces 10,4121–4130. Ø Md. M. M. Alam, S. K. Ghosh, A. Sultana, and D. Mandal*, 2018, An Efficient Wind Energy Harvester of Paper Ash-Mediate Rapidly Synthesized ZnO Nanoparcle-Interfaced Electrospun PVDF Fiber, ACS Sustainable Chem. Eng. 6, 292–299. Ø S. K. Ghosh, M. Xie, C. R. Bowen, P. R. Davies, D. J. Morgan and D. Mandal*, 2017, A hybrid strain and thermal energy harvester based on an infra-red sensive Er3+ modified poly(vinylidene fluoride) ferroelectric structure, Scienfic Reports 7, 16703, DOI: 10.1038/s41598-017-16822-3.

Sanconed projects: Fabricaon of Flexible Piezoelectric Energy Harvester for Developing the Self-Powering System, SERB-EMEQ (PI).

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4) Dr. Indranil Sarkar, Scienst E Research area of interest: I have started a group called Spin Harvesng in nano-Engineerd Devices (SHAPED). The group will work on spintronics based plaorm for device applicaon. The aim of this group will be to develop novel materials and plaorms based on spin degree of freedom of charge carriers that will find device applicaon in energy harvesng, magnec memory devices and sensors. The research will combine unique property of spin and its co- operave interacon at nanoscale to engineer efficient nanostructures that can be used for developing devices. Design of these material plaorms will be guided by the requirement that their use in devices shall lead to lower power consumpon, faster performance and mul- funconality 5) Dr. Kaushik Ghosh, Scienst D Research area of interest:Electronics: Advance 3D-IC packaging, CNT-TSV / Cu-TSV interconnect fabricaon, Characterizaon & Reliability Study, Carbon based piezoelectric device. Energy : Advanced Material Synthesis for Solar Cell Applicaon / Renewable Energy, Noncorrosive hydrophobic ARC coang for Solar glass, All Carbon based Transparent /Flexible micro-coil Supercapacitor, Novel Photo catalyst for PEC water spling, Graphene-CNT based facile coang on Copper sink: For chip cooling Sensor: CNT/Graphene based-FED/FET device, Graphene- nanoribbon based NEMS detector, Novel Graphic VACNT magnec coils for NMR tomography/Cancer Hydrophobic, An-corrosive AR Coang Figure: The3D schemac representaon of (a) nanoporous silica coang on glass substrate without graphene layer, where the contact angle of the water droplets is θ <50º, (b) nanoporous silica coang on glass substrate with graphene layer, where the contact angle of the water droplets is θ >90º In this work, for the first me, we have demonstrated that graphene can be used to enhance the hydrophobicity of nanoporous silica based single layer anreflecve coang. High transmiance with high hydrophobic noncorrosive anreflecve (AR) coang of Graphene/Nanoporous-silica heterostructure is designed for advance solar devices. The prolong acid test for long term durability imparts to hydrophobic, an-corrosive and robust nature of this AR coang without alteraon of wide angle and broadband transmiance. Publicaons Ø Udaya Kumar, Khushboo Soni, S. Suresh, Kaushik Ghosh, M.R. Thansekhar, P. Dinesh Babu Modified Surfaces Using Seamless Graphene/Carbon Nanotubes Based Nanostructures for Enhancing Pool Boiling Heat Transfer” Experimental Thermal and Fluid Science; 96 (2018) 493-506.DOI: hps://doi.org/10.1016/j.expthermflusci.2018.03.038 Ø Kulvinder Singh, Sushil Kumar, Kushagra Agarwal , Khushboo Soni, Venkata Ramana Gedela & Kaushik Ghosh, Three dimensional Graphene with MoS2 Nanohybrid as Potenal Energy torage/Transfer Device, Scienfic Reports; 7, 9458(2017); DOI:10.1038/s41598-017- 09266-2.

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6) Dr. Kiran Shankar Hazra, Scienst C Our research acvity is mostly focused on exploring opcal and electronic response of nanostructured 2-D layered materials. We are also working on developing 2-D layered materials based nano-sensors and transducers. Apart from these, we have an interest in applicaons of nano-composites of 2-D layered materials such as flexible electronics, coang technology and in energy devices Two-dimensional (2-D) layered materials such as graphene, phosphorene and transion metal dichalcogenides (TMDs) like MoS2, WS2 are capable materials for next-generaon Nano electronic devices. Various 2-D layered materials exhibit metallic, insulang or semiconducng properes depending upon layer thickness and demonstrates unique opcal and electronic response. Due to these properes, it opens an unprecedented prospect of miniaturizing electronic and optoelectronic devices, chemical & biosensors plaorm. Our group is focused on exploring the fundamental opcal and electronic properes and novel funconality of these 2-D layered materials. Creang nanostructures on 2-D layered materials is one of the major challenge to realize its applicaon in nanoelectronics and opto-electronics. However, the exisng convenonal fabricaon technique has their own drawback such as isotropic etching rate, usage of of chemicals and complicated equipment set ups. Our group is interested in fabricang nanostructures on these 2D nano-materials using the simple, reliable and economical method. We have developed a novel technique to fabricate the nanostructures on these materials by using simple one step focused laser irradiaon technique which is simple one step process and free from chemical contaminaon. Our research interest lies in exploring the opcal and electronic response of various nanostructures, fabricated on 2D layered nanomaterials. We are also working on nanocomposites of 2-D layered materials for applicaons in flexible electronics, energy devices, sensing and coang technology. Our complementary approach provides the capability to gain deep insight into the fundamental mechanism of light to maer interacons.

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7) Sh. Bhanu Prakash, Scienst C The research is focused on experimental microfluidics and micro-nano fabricaon for device applicaons. Synthesis of novel nanostructures using microfluidic route for photocatalyc and photovoltaic applicaons is ongoing work. We are also developing new microfluidic plaorm for connuous and droplet microfluidics via me effecve and low cost route avoiding the use of expensive lithographic setups. To combine surface enhanced Raman spectroscopy (SERS) and plasmonics with microfluidics for different device based applicaons is also being explored. The work is focused towards designing new devices for energy conversion/harvesng and development of sensors for food safety, environmental safety and in parcular homeland security applicaons. My research involves thin film deposion, lithography, bonding, dry (plasma) as well as wet etching, laser/focused ion beam assisted etching, deep reacve ion etching and working in a clean room environment. Apart from this, in collaboraon, we are also working on perovskite oxide interfaces, synthesis of pepde nanostructures and development of devices for biomedical use with Dr. Suvankar Chakraverty, Dr. Jiban J Panda and Dr. Patra at INST Mohali. Publicaons: Ø Wadehra, N.; Tomar, R.; Halder, S.; Sharma, M.; Singh, I.; Jena, N.; Prakash, B.; Sarkar, A. D.; Bera, C.; Venkatesan, A.; Chakraverty, S.; Ar+ bombardment induced electronic band modificaons in KTaO3 single crystal surfaces, Phys. Rev. B, 2017, 96, 115423. Fig : Micro and Nano fluidics for Ø Tomar, R.; Wadehra, N.; Budhiraja, V.; Prakash, Sensing and Device Applicaons B.;* Chakraverty, S.; Realizaon of single terminated surface of perovskite oxide single crystals and their band profile: (LaAlO3)0.3(Sr2AlTaO6)0.7, SrTiO3 and KTaO3 case study, Appl. Surf. Sci., 2017, 427, 861. Ø Kumar, N.; Tomar, R.; Wadehra, N.; Devi, M. M.; Prakash, B.;* Chakraverty, S.; " Growth of highly crystalline and large scale monolayer MoS2 by CVD: The role of substrate posion, Cryst. Res. Technol. 2018, 1800002. Ø Baruah, A.; Singh, A.; Sheoran, V.; Prakash, B.;* Ganguli, A. K.; Droplet-microfluidics for the controlled synthesis and efficient photocatalysis of TiO2 nanoparcles, Mater. Res. Express, 2018, 5, 7. Ø Singh, A; Baruah, A.; Vaghasiya, K.; Prakash, B.;* Ganguli, A. K.; Microreactor based synthesis and photocatalysis of Ag3PO4 nanoparcles with greater photostability and anmicrobial efficiency, J. Photochem. Photobiol A, 2018, 364, 382.

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8) Dr. Chandan Bera, Scienst C Research area of interest: Dr. Chandan Bera is working on thermal and electrical properes of nano structure materials for renewable energy applicaon. More specifically for applicaon on thermoelectric, thermal insulaon, thermal storage etc.

Fig: (a) Crystal structure of PdPS, (b) Band diagram, (c) and (d) power factor for ntype and ptype PdPS in different direcon. It is found that for n-type z direcon of crystal have very high power factor compare to bulk and for p-type very high power factor is observed in y direcon. Publicaons: Ø Chandan Bera, Surendra B. Devarakonda, Vishal Kumar, Ashok K. Ganguli and Rupak K. Banerjee, The mechanism of nanoparcle-mediated enhanced energy transfer during high-intensity focused ultrasound sonicaon. Phys. Chem. Chem. Phys.19, 19075–19082 (2017). Ø Prabhjot Kaur, Chandan Bera, Effect of alloying on thermal conducvity and hermoelectric properes of CoAsS and CoSbS, Phys. Chem. Chem. Phys.19, 24928–24933 (2017). Ø Neha Wadehra, Ruchi Tomar, Soumyadip Halder, Minaxi Sharma, Inderjit Singh, Nityasagar Jena, Bhanu Prakash, Abir De Sarkar, Chandan Bera, Ananth Venkatesan, S Chakraverty, Electronic structure modificaon of the KTaO 3 single-crystal surface by Ar+ bombardment, Phys. Rev. B96, 115423 (2017).

Projects Sanconed: Ø Computaonal study of spin polarizaon in ternary chalcogenide, SERB-EMEQ (PI) Ø Method development for measurement of thermal properes (especially thermal conducvity) for heat transfer materials at higher temperature, IOCL R&D (PI) Ø Biomass Derived Nanostructured Cellulose Aerogel Materials for Thermal Insulaon in Energy Efficient Smart Buildings, DST-CERI, (Co-PI) Ø Low temperature growth of carbonaceous heterostructure for magnec and thermal applicaon, DST-NanoMission, (Co-PI) Ø Computaonal predicon of novel thermoelectric nanomaterials, DST-SERB-EMR. (PI) Ø Extracon of nanostructured materials from gaseous effluents of power plant,NTPC- NETRA.(Co-PI) 32 Institute of Nano Science And Technology

9) Dr. Neha Sardana, Scienst B Research area of interest: Our group is involved in theorecal and experimental studies involving electromagnec wave and maer interacons with an aim for device fabricaon. The key research interests are:

Ø Designing plasmonic structures for low cost sensing applicaons especially biosensing. eg: FET Based devices, Opto Electronic devices, etc. Ø Nanostructured materials especially photonic crystals for energy harvesng Ø Fabricaon and study of different gels (silica aerogel, graphene aerogel, metallogels etc.) as substrates for opcal studies.

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III. NANOTECHNOLOGY FOR ENERGY AND ENVIRONMENT:

1) Prof H. N. Ghosh: Group Coordinator

2) Dr. Kamalakannan Kailasam, Scienst E

Research highlights: Advanced Funconal Nanomaterials: Energy and Environmental Applicaons like Photocatalyc Water Spling, Biomass Conversion to Fine Chemicals Producon, Photovoltaics and Sensors using Heptazine based Carbon Nitride Polymers. One of our sensing is highlighted below: Figure:Highly sensive and fast responsive relave humidity (%RH) sensor based on In-SnO2 loaded cubic mesoporous graphic carbon nitride (g-C3N4).In-SnO2/meso-CN nanohybrid demonstrated superfast response (3.5 s) and recovery (1.5 s) in 11-98 %RH range at room temperature (graph, le above). Repeated response and recovery curves for In-SnO2/meso- CN measured in 5 loops in 11-98 %RH range shows similar impedence values, which reveals that the response of In-SnO2/meso-CN sensor is highly reversible (graph, le below).These results open the door for breath monitoring and shows promising glimpse for designing mesoporous 2D layered materials in the development of futurisc ultrasensive %RH sensors.

Publicaons : Ø Bhumica Agarwal, K. Kailasam, R. S. Sangwan and S. Elumalai “Traversing the History of Solid Catalysts for Heterogeneous Synthesis of 5-Hydroxymethylfurfural from Carbohydrate Sugars: A Review” Renewable and Sustainable Energy Reviews, 2018, 82, 2408–2425. Ø R. Malik, V. K. Tomer*, V. Chaudhary, M. S. Dahiya, S. P. Nehra, S. Duhan and K. Kailasam* , “A Low Temperature, Highly Sensive and Fast Response Toluene Gas Sensor Based on In(III)-SnO2 Loaded Cubic Mesoporous Graphic Carbon Nitride“ . Sens. Actuators B, 2018, 255, 3564-3575.

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Ø H. Singh, V. K. Tomer, N. Jena, I. Bala, N. Sharma, D. Nepak, A. De Sarkar,* K.Kailasam* and S. K. Pal*. “A Porous, Crystalline Truxene-based Covalent Organic Framework and its Applicaon in Humidity Sensing” J. Mater. Chem. A, 2017, 5, 21820-21827. Ø I. Bala, H. Singh, V. R. Baula, S. P. Gupta, J. De, S. Kumar, K. Kailasam* and S. K. Pal* “Heptazine: A new electron deficient fluorescent core for discoc liquid crystals. Chem. Eur. J.,2017, 23, 14718-14722. Ø V. K. Tomer, R. Malik and K. Kailasam*, “Near Room Temperature Ethanol detecon using Ag-loaded Mesoporous Carbon Nitrides” ACS Omega, 2017, 2 (7), 3658–36 Ø Malik, R.; Tomer. V. K.; Chaudhary, V.; Dahiya, M. S.; Nehra, S. P.; Duhan, S.; Kailasam, K.J. Mater. Chem. A 2017,5, 14134-14143. Sponsored Projects: Photocatalyc-driven Hydrogen Generaon and Cellulosic-Biomass Conversion using Mesoporous Carbon Nitrides: DST-SERB-E ; 2)Biomass Derived Nanostructured Cellulose Aerogel Materials for Thermal Insulaon in Energy Efficient Smart Buildings: DST-CERI; 3)Prototype Large-Scale Reactor for Simultaneous Producon of H2 and Fine Chemicals under Natural Sunlight DST-Nano Mission-NATDP; 4)Method development for measurement of thermal properes (especially thermal conducvity) for heat transfer materials at higher temperature: IOCL R&D.

3) Dr. Abir De Sarkar, Scienst E A synergic coupling between the semiconducng and piezoelectric properes in single layer MoS2 has been explored in our studies via density funconal theory for the opmizaon of nanoelectromechanical energy conversion/harvesng and its nanopiezotronic properes [J. Phys. Chem. C 121 (2017) 9 1 8 1 – 9 1 9 0 ] . Va r i a o n i n piezoelectric and semiconducng properes, and carrier mobility with the applicaon of strain of all kinds have been studied to ascertain the type and magnitude of strain under which the energy conversion and the carrier mobility are simultaneously and opmally enhanced. Effects of strain and pH on photocatalyc acvies in single layer MoS2 has been comprehensively studied in our work in terms of band edges straddling the redox potenal, opcal conducvity and absorbance, carrier mobility and carrier mobility rao [J. Mat. Chem. A, 5 (2017) 22265-22276]. The mechanism underlying the opmal enhancement in the thermoelectric power factor in monolayer MoS2 under the applicaon of strain has also been invesgated using density funconal theory coupled to Boltzmann transport equaon [J. of Phys.: Cond. Ma. 29 (2017) 225501 (7pp)]. These are independent theorecal work from my Group with my PhD students. Besides these, I have also collaborated with my experimentalist colleagues and have provided them the theorecal support.

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Publicaons: Ø Jena, N.; Dimple; Behere, S. D.; De Sarkar, A. Strain-Induced Opmizaon of Nanoelectromechanical Energy Harvesng and Nanopiezotronic Response in a MoS2 Monolayer Nanosheet. J Phys Chem C2017, 121, 9181–9190. Ø Dimple; Jena, N.; Rawat, A.; De Sarkar, A. Strain and PH Facilitated Arficial Photosynthesis in Monolayer MoS2 Nanosheet. J Mater Chem A2017, 5, 22265–22276. Ø Dimple,; Jena, N.; De Sarkar, A. Compressive Strain Induced Enhancement in Thermoelectric-Power-Factor in Monolayer MoS2 Nanosheet. J Phys Condens Maer2017, 29 (22), 225501. Ø Wadehra, N.; Tomar, R.; Halder, S.; Sharma, M.; Singh, I.; Jena, N.; Prakash, B.; De Sarkar, A.; Bera, C.; Venkatesan, A.; et al. Electronic Structure Modificaon of the KTaO3 Single-Crystal Surface by Ar+ Bombardment. Phys Rev B2017, 96, 115423. Ø Singh, H.; Tomer, V. K.; Jena, N.; Bala, I.; Sharma, N.; Nepak, D.; De Sarkar, A.; Kailasam, K.; Pal, S. K. A Porous, Crystalline Truxene-Based Covalent Organic Framework and Its Applicaon in Humidity Sensing. J Mater Chem A2017, 5, 21820–21827.

Dr Abir with Prof Rao

Sponsored projects: Individual centric Extramural Research (EMR) Grant from DST, Nano Mission Award: Prof CNR Rao Award for Excellence in Nano research for the year 2018

4) Dr. P.S. Vijayakumar, Scienst C To design nanoparcles suitable for agricultural pracces like nutrient, pest and diseases management. In the context of pescide, a graphene oxide based pescide delivery system that can resist the dri loss is developed. Here we discovered graphene oxide to show ~400% pescide loading (w/w). The graphene oxide was further decorated with copper selenide, which have photothermal and photocatalyc property. Photothermic property complements with graphene oxide in pescide delivery, which may control diurnal pest. The photocatalyc

36 Institute of Nano Science And Technology property aid in programmed pescide residue degradaon in the offsite. This nano-carrier shows dri resistance in addion to targeted release, which enhanced larval mortality by >35%. In case of ferlizer delivery, a plant smuli readable ferlizer delivery system for the efficient plant uptake was developed. Here the nano coang funcons as latent gate, that close and avoid ferlizer loss; whereas open to release the nutrients selecvely to the root. To develop nanotechnology for food preservaon and forficaon with high nutrion quality and minimum chemical intervenon. Publicaons: Sharma S.; Singh S.; Ganguli A. K.; Vijayakumar, P. S. An-dri nano-sckers made of graphene oxide for targeted pescide delivery and crop pest control. Carbon 2017, 115, 781-790. 5 ) Dr. Sonalika Vaidya, Scienst C Design of anisotropic, core-shell and self-assembled nanostructures with ideal and controllable morphology, size, and structure with improved performance for solving persistent issues related to energy and environment. The nanostructures Effect of Mg doping on Photocatalyc acvity of SnS2 designed are studied for their photocatalyc and electrocatalyc applicaons. Formaon of oriented assemblies of nanostructures for improved performances. Our group is also focussed on study of nucleaon and growth of nanostructures using SAXS. In this study, we are trying to study the effect of variaonin co- surfactant on the growth mechanism of copper oxalate within the microemulsion using SAXS.

Study of Nucleaon and Growth of Nanostructures Using SAXS

CTAB/1-butanol/iso-octane/copperoxalate CTAB/1-octanol/iso-octane/copperoxalate

Project Sanconed: Oriented assemblies of ferroelectric nanostructures with enhanced polarizaon for Photocatalyc water spling, CSIR.

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6) Dr. Tapasi Sen, Scienst C

Fabricaon of plasmonic nanostructures based on DNA origami, Development of DNA- directed self-assembled nanoantennas to get strong Fluorescence/SERS enhancement for biomolecular assays and sensing applicaons, Design of nanostructures materials with unidireconal energy transfer for developing efficient light harvesng systems,Nano-bio- interacons study using single-molecule fluorescence spectroscopy, Our group has recently designed Au nanostar dimers with precisely tunable interparcle gap

and controlled stoichiometry assembled on DNA origami. Au nanostars with uniform and sharp ps were immobilized on rectangular DNA origami dimerized structures. The SERS enhancement factors of single Texas red dye molecules placed in the centre of dimeric structures having interparcle gaps of 7 and 13 nm are 2 × 1010 and 8 × 109, respecvely,which are strong enough for single analyte detecon. The highly enhanced electromagnec field generated by the coupling of sharp ps of Au nanostars exhibits excellent SERS sensivity in the wide conjuncon region that allows the accommodaon and specific detecon of large biomolecules. Such DNA-directed assembled nanoantennas with controlled interparcle distance and stoichiometry, can be used as excellent substrates in single-molecule SERS spectroscopy and will have potenal applicaons as a cost-effecve and reproducible plaorm in single-molecule sensing.

Publicaons Ø DNA Origami Directed Au Nanostar Dimers for Single-Molecule Surface-Enhanced Raman Scaering.Tanwar, S.; Haldar, K.K.; Sen, T. J Am Chem Soc2017, 139, 17639. Ø Core size maers! High Raman enhancing core tunable Au/Ag bimetallic core-shell nanoparcles. Paital, D.; Sen, T.; Patra, A.;Haldar, K.K.Gold Bullen 2017, 50 (4), 313.

Sanconed project Project entled “Plasmonic enhancement of single molecule fluorescence by metallic nanoantennas assembled on DNA origami”sanconed by SERB ECR.

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7) Dr. Menaka Jha, Scienst C Nanostructured materials and their applicaon to make electronic devices, Low temperature stabilizaon of boron based materials (borane, boride and borates) and stabilizaon of higher oxidaon states in binary and ternary metal oxides, Quantum dots based Colloidal nanostructures and their applicaon in making flexible electronic devices, Producon and storage of H2 using nanostructured materials Global warming is a burning issue worldwide because of toxic components in the polluted air causes several health issues. The polluted air is generally composed of smoke, dust, and greenhouse gases (flue gases). Recently, our research group at INST Mohali have been working in the field of treatment of industrial efflent (toxic gases) as well as liquid effluents. We are also working on the recovery of valuable materials from industrial eflluent.

Conversion of industrial waste (flue gas or corrosive effluents) into nanostructured materials

To meet our above objecve, we have been working with chemical industry (C. S. Zircon Pvt. Ltd. ) as well as power plants. With the help of themal power plant (NTPC Netra), we have developed a technology to convert power plant pollutants to valuable materials which is in high demand. Our team has ulized gaseos effluents and we have been successfully converted these materials to industrially important material. The lab scale as well as pilot scale studies has been completed and looking forward to have industrial scale set-up at NTPC power plant. INST and NTPC now planning to take up this to the commercial scale. My group is also acvely working in the area of water purificaon, where our main aim is to help society to get safe water. We have been intensively working on applicaon of nanotechnology in fabricaon of various cartridges. 39 Institute of Nano Science And Technology

Apart from the above work, my group is also working in the field of synthesis of nanostructured materials and their applicaon. We have been successfully able to stbilized controlled shaped metal oxide, metal borides and metal phosphides and ulized these materials into fabricaon of field emier, supercapacitor, Li ion baery and photocatalysis. Currenly, the applicaon of all these materials have been studied at lab scale and we are looking forward to make suitable product out of these materials.

Projects sanconed: Ø Extracon of nanostructured materials from gaseous effluents of power plant” sanconed by Naonal Thermal Plant Corporaon (Budget 50 lacs for 2 year). Group: Dr. Menaka Jha, Dr. Chandan Bera and Prof. A. K. Ganguli Ø Extracon of valuable product from industrial waste” sanconed by C.S. Zircon Product Pvt. Ltd. (Budget 19 lacs for 6 month), Group: Dr. Menaka Jha, Dr. S. Vaidya, Dr. V. Bagchi and Prof. A. K. Ganguli Ø Validaon of cartridge for purificaon of water contaminated with arsenic sanconed by Naonal Instute of Foundaon: Group: Dr. Menaka Jha and Prof. A. K. Ganguli Ø Development of prototype for removal of toxic impurity from waste water sanconed by INST Mohali (Group: : Dr. Menaka Jha and Prof. A. K. Ganguli ; Budget: 9.96 lacs). Ø Design of process for enameling of the gold surface Jewelry using colored gold Nanoparcles (POC development), sanconed by Titan, Tanishq Group: Dr. Menaka Jha and Prof. A. K. Ganguli, Budget: 11 lacs for 6 month. Ø Technology for commercial scale up for process entled “Synthesis of N-doped graphene” by NTPC Netra, Menaka Jha, Budget~ 10 lacs. Ø Method development for measurement of thermal properes (especially thermal conducvity) for heat transfer material at higher temperatures Sanconed by Indian Oil Corporaon (Budget 65 lacs), Group: C. Bera, K. Kailasam, M. Jha and A. K. Ganguli Ø Prototype Large-scale reactor for simultaneous producon of H2 and fine chemicals under natural sunlight by Department of Science and Technology (Budget: Rs. 1090 lakh), Group: K. Kailasam, A. K. Ganguli, V. Bagchi, S. Naidu and M. Jha Publicaons: Ø Low Temperature synthesis process of stabilizaon of cubic yria stabilized zirconia spindles an important high temperature ceramic material K K Yadav, A Gupta, M Sharma, N Dabas, A K Ganguli, M Jha, Materials Research Express, 2017, 4 (10), 105044 Ø Invesgaon of the growth mechanism of the formaon of ZnO nanorods by thermal decomposion of zinc acetate and their field emission properes , M Sreekanth, S Ghosh, SK Mehta, AK Ganguli, M Jha, Cryst Eng Comm, 2017 19 (16), 2264-2270 Ø Nanocuboidal-shaped zirconium based metal organic framework for the enhanced adsorpve removal of nonsteroidal an-inflammatory drug, ketorolac tromethamine, from aqueous phase S Singh, S Sharma, A Umar, M Jha, SK Mehta, S K Kansal, New Journal of Chemistry, New J. Chem., 2018,42, 1921-1930

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Ø Room temperature synthesis of urea based imidazole funconalised ZnO Nanorods and their photocatalyc applicaon , J Mishra, M Jha, N Kaur, AK Ganguli, Materials Research Bullen, 2018, 311-318. Ø Microemulsion based approach for nanospheres assembly into anisotropic nanostructures of NiMnO3 and their magnec properes, M Jha, S Kumar, N Garg, KV Ramanujachary, SE Lofland, AK Ganguli, Journal of Solid State Chemistry, 2018, 258, 722- 727 Ø Efficient synthesis and characterizaon of Cu20Se03 nanoparcles via hydrothermal route , M M Devi, M Jha, A K Ganguli, S Chakraverty, Materials Research Express, 2017, 4 (11), 115007. Ø Transformaon of Waste Tin Plated Steel to Iron Nanosheets and Their Applicaon in Generaon of Oxygen, Manolata Devi, Kasinath, A. K. Ganguli and M. Jha, Internaonal Journal of Environmental Science and Technology, 2018, Just accepted Ø New low temperature process for stabilizaon of nanostructured La2NiMnO6 and their magnec properes, Viswajit, Suvankar Chakravorty, S. E . Lofland, K. V. Ramanujachary, Ashok Kumar Ganguli, Menaka Jha*, Journal of Magnesm and Magnec Materials, 2018, Just accepted

8) Dr. Vivek Bagchi, Scienitst C The design and synthesize new nanoscale materials and structures with an emphasis on raonal control of morphology, size, structure, composion and doping of metal carbides and nitrides on mulple scales for electrocatalyc applicaons.; Nano structured composite materials for photoelectrochemical applicaons.; Metal-Air Baeries and hybrid energy storage devices; Acve catalysts for Oxygen Reducon Reacon for Nonaqueous Li-Air

Baeries; Development of low cost, stable and efficient electrocatalyst for development of PEMFC; MOF based polymer electrolyte; Nano-materials mediated catalysis for organic transformaons; Engineered nanomaterials for Air/Water purificaon. Publicaon: Nano-structured hybrid Molybdenum Carbides / Nitrides generated in-situ for HER Applicaons; Rajinder Kumar, Ritu Rai, Seema Gautam, Abir De Sarkar, N. Tiwari, Shambhu Nath Jha, Dibyendu Bhaacharyya, Ashok K Ganguli and Vivek Bagchi, J. Mater. Chem. A, 2017, 5, 7764.

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9) Dr. Monika Singh, Scienst C My group is working on developing Metal Organic Framework based Porous Nanostructures for Applicaons in Energy and Environment. At present her group focuses on developing of new MOFs for carbon dioxide capture and its catalyc conversion to useful carbonates.

Excellent Catalyc Fixaon of CO2 by Metal-Organic Polymers under Mild Condions Carbon dioxide, a greenhouse gas, being non-toxic and non-flammable serves as a building block in organic synthesis. But its excessive concentraon in the environment has become a major issue and aracted global interest to resolve this problem in a more environmentally benign way. Carbon dioxide being one of the major constuents of global warming gases needs

to be stored or converted into a more useful form of fuel and industrial chemical feedstock. Its chemical fixaon is essenal due to its varied use and also very challenging due to its kinec inertness and thermodynamic stability. CO2 catalyc fixaon has given a very efficient way to get rid of this problem to some extent. A series of Metal-Organic Frameworks (MOFs) based on trimesic acid (btc) have been synthesized using a solvothermal procedure which exhibits excellent catalyc fixaon of CO2. Cycloaddion of CO2 to epoxide to produce cyclic carbonates is quite promising. The chemical fixaon of CO2 reported here is solvent free and carried out under moderately mild condions. All MOFs [Zn-btc (1), Co-btc (2), Ni-btc (3), Cu- btc (4)] show almost 100% conversion in these reacons. All the catalysts follow first-order kinecs, and Zn-btc (1) proved to be the most catalycally acve catalyst among all with ~100% yield with a total turnover number of 18,845 per mole of catalyst and an inial TOF (hour-1) of 946 with respect to Cyclic carbonate. Same reacon using other metal (Co, Ni, Cu)-btc compounds have also yielded product more than 94 % creang an extra impact on the importance of the work.

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10) Dr. Sanyasinaidu Boddu, Scienst B Due to increasing energy needs of the society, depleon of fossil fuels and serious environmental problems accompanying their combuson, modern society has been searching for a new form of energy that is a clean, renewable alternave to fossil fuels. Solar energy is a clean, abundant and economical energy source. But it cannot be used as such; it must be captured and converted into a useful form of energy. Our research is focused on synthesis of novel metal oxide nanomaterial and their applicaons to solar energy conversion (photocatalyc water spling, arficial photosynthesis, photocatalyc CO2 reducon), photocatalyc degradaon of organic pollutants and energy saving (phosphors based light eming devices, LED). LaFeO3/Ag2CO3 heterostructure nanocomposites have been synthesized by co-precipitaon method for the photocatalyc degradaon of Rhodamine B (RhB) dye and p-chlorophenol. It is observed that these heterostructures show the much beer photocatalyc acvity with respect to their individual counterparts and the highest catalyc acvity is observed with 1% LaFeO3/Ag2CO3 sample. 98.8% of RhB is degraded in 45min under the visible light irradiaon. It is found that 99.5% of RhB and 59% of p-chlorophenol degradaon takes place in 45min under natural sunlight. Recycling experiments demonstrate that nanocomposites show excellent catalyc acvity and stability whereas the acvity of pure Ag2CO3 decreases in successive cycles of reuse due to the formaon of Ag0 phase. Reacve Oxygen Species (ROS) scavenging experiments suggest that the holes and HO radicals are playing crucial role in the degradaon process.

2) Publicaons Journal: Kamal, Ch. S.; Boddu, S.; Vishwanadh, B.; Rao, K. R.; Vatsa, R. K.; Sudarsan, V., Blue luminescence from ZnGa2O4: Effect of lace distoron and parcle size, J. Lumin. 2017, 188, 429-435. Book Chapter: S. Boddu, N. Thangaraj, K. Kailasam, Visible light heterogeneous catalysts for photocatalyc CO2 reducon, in Visible Light-Acve Photocatalysis: Nanostructured Catalyst Design, Mechanisms, and Applicaons Edited by Sraban Ghosh, John Wiley & Sons, Inc. 2018.

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11) Dr. Ramendra Sundar Dey, Scienst B Research Highlights : Energy storage technology and sensing with bio-inspired graphene and its composies Self-sustainable integrated energy storage systems can be the most plausible soluon since we are on the verge of a global energy crisis due to rapid dissoluon of fossil fuels. Finding environmentally benign fossil fuel replica with a broad performance spectrum is sll a very encouraging field of research. Increasing craze for portable electronics and hybrid vehicles are raising the bar for the model energy storage systems with high specific energy and power. In recent mes, a tremendous effort related to energy storage device has been put by our research groups. We are currently involved to develop sandwich as well as in-plane supercapacitor with carbonaceous materials and supercapacitor-biofuel cell hybrid system and technologies. Wire-based flexible supercapacitor: An easy and cost-effecve approach for the growing of porous electrochemically reduced graphene oxide networks on copper wire, modified with galvanostacally deposited copper foam was demonstrated. The electrodes were assembled on the flexible sheet in a planar configuraon with an ionogel as an electrolyte as well as a separator. The combinaon of large-scale producon of porous 3D graphene by the electrochemical approach and high electrochemical performance of porous graphene on Cu wire paves-the-way for wearable and texle applicaon. This wire-based all-solid-state supercapacitor is highly flexible, which can be assembled with/without a flexible substrate in different geometries and bending angles for illustrang propious use in smart texle and wearable device. Bio-inspired high surface area graphene for energy storage device: Large area Few-layer graphene-like nanosheets with an abundance of micro as well as mesopores are achieved via a user-friendly mechanical exfoliaon method from an agricultural waste biomass source, peanut shell. A well-known elementary method of probe-sonicaon, for the

achievement of FLG sheets from renewable sources, is introduced in this study for the very first me. The Peanut shell-derived few layer graphene possesses remarkably high Brunauer–Emme–Teller surface area (SBET = 2070 m2 g-1) with a sufficiently large pore 44 Institute of Nano Science And Technology achieved via a user-friendly mechanical exfoliaon method from an agricultural waste biomass source, peanut shell. A well-known elementary method of probe-sonicaon, for the achievement of FLG sheets from renewable sources, is introduced in this study for the very first me. The Peanut shell-derived few layer graphene possesses remarkably high Brunauer–Emme–Teller surface area (SBET = 2070 m2 g-1) with a sufficiently large pore volume. The PS-FLG material is good for applicaon in supercapacitor and shows high specific capacitance of 184 F g-1 and wide voltage range of 2.5 V with organic electrolyte and a promising energy density was aained with this material. A solid-state supercapacitor device was fabricated with the materials to show that the PS-FLG materials have potenal for the applicaon as supercapacitor device.

Layer-by-layer assembly of gold nanoparcles and reduced graphene oxide three-dimensional nanohybrid for DNA sensor: One-step electrodeposion-assisted assembly of gold nanoparcles (AuNPs) and reduced graphene oxide (rGO) for the ultrasensive electrochemical impedance sensing of DNA hybridizaon was demonstrated. This study presents a promising electrochemical sensing plaorm for the label-free ultrasensive detecon of DNA with possible applicaon in cancer diagnoscs and the preparaon of a self- healable nanohybrid thin film with a 3D alternate-layered Nano architecture.

Publicaons:

Ø Jayakumar Kumarasamy, María Belén Camarada, Dharuman Venkatraman,* Huangxian Ju, Ramendra Sundar Dey* and Yangping Wen*, One-step coelectrodeposion-assisted layer- by-layer assembly of gold nanoparcles and reduced graphene oxide and its self-healing three-dimensional nanohybrid for an ultrasensive DNA sensor. Nanoscale, 2018, 10, 1196-1206. Ø Soumik Mitra, Krishnendu Pramanik, Pallab Ghosh, Tithi Soren, Anumita Sarkar, Ramendra Sundar Dey, Sanjeev Pandey, Tushar Kan Mai*, Characterizaon of Cd-resistant Klebsiella michiganensisMCC3089 and its potenal for rice seedling growth promoon under Cd stress, , Microbiological Research 210 (2018) 12–25. Ø Taniya Purkait, Guneet Singh, Dinesh Kumar, Mandeep Singh and Ramendra Sundar Dey*, High-performance flexible supercapacitors based on electrochemically tailored three- dimensional reduced graphene oxide networks. Sci. Rep., 2018, 8, 640. Ø Taniya Purkait , Guneet Singh , Mandeep Singh , Dinesh Kumar and Ramendra Sundar Dey*, Large area few-layered graphene with scalable preparaon from waste biomass for high- performance supercapacitor. Sci. Rep. 2017, 7, 15239.

Technology Developed/being developed: 1) Technology for the synthesis of high surface area few-layered graphene from biomass waste;2) Highly efficient and cost-effecve technology for the free-standing three-dimensional graphene oxide networks.

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IV. SOFT NANOSTRUCTURE

1) Prof. Deepa Ghosh, Scienst – F and Group Coordinator

Development of injectable gels for cell implantaon: The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote ssue regeneraon in the body is of growing interest. Our group is involved in the development of low cost biocompable and biodegradable injectable hydrogels from a variety of natural and synthec polymeric building blocks for delivering cells to address carlage damage. These building blocks are engineered to enable crosslinking by chemical reacon or through physical interacons which on injecon leads to in situ hydrogel formaon.

2) Dr. Prakash Neelakandan, Scienst E

Ø Photochemistry of organic nanomaterials: We are working on developing organic nanomaterials with the aid of supramolecular chemistry. We synthesize simple organic molecules which are then induced to self-assemble into nanomaterials. The photophysical and photochemical properes of these materials were studied and our results demonstrate that the supramolecular nanomaterials exhibit superior properes as compared to the individual components. Ø Nucleic Acid Analogues: Synthec nucleic acids are widely used for research, medical diagnosis, and drug development. Some of them have been commercialized as drugs, and several are undergoing clinical trials. However, the synthec challenge involved in the preparaon of new funconalized oligonucleodes is restricng their wide-spread development. We aim to develop new methodologies based on dynamic covalent chemistry to synthesize nucleic acid analogues for therapeuc applicaons.

Publicaons: Supramolecular confinement within chitosan nanocomposites enhance singlet oxygen generaon. K Naim, ST Nair, P Yadav, A Shanavas, PP Neelakandan*, ChemPlusChem, 2018, in press (DOI: 10.1002/cplu.201800041). Sponsored project: Dynamic Self- assembled Nucleic Acid Analogues. 46 Institute of Nano Science And Technology

3) Dr. Asish Pal, Scienst E Research Area: (A) Smuli-responsive collapse of Single Chain Polymer to form Nanoparcles of uniform size: Single chain polymer with different percentage loading of photo responsive groups are being designed. These photo-responsive groups (e.g. Coumarin moees) upon UV radiaon dimerizes and folds the chain in discrete nanoparcles. The UV spectroscopy can be efficiently used to monitor the dimerizaon process, which demonstrates gradual diminishing of the 320 nm peak. The AFM image shows formaon of uniform sized (Dav = 50 nm) nanoparcles. The glass-transion temperature for uncross linked and photo-crosslinked polymer showed remarkable difference that can be ulized for tunable self-healing applicaons.

(B)Living supramolecular polymerizaon for length control in pepde nanofibers: Pepdes fibers with amyloid core sequence f o l l o w s n u c l e a o n mediated growth and hence can be controlled kinecally by living s u p r a m o l e c u l a r polymerizaon. Thus, s h o r t fi b e r s w e r e prepared and nucleated with different percentage of seeds to get length control over the fibers (le). Eventually, these fibers with uniform length distribuon in different length regime can crosslinked to form hydrogels, which are mechanically tunable. Spontaneous formaon of supramolecular metallo-hydrogels showing mul smuli-responsiveness and self-healing property at room temperature upon the interacon of L- or D-hisdine with Zn2+ ions. Anchoring hisdine onto pepde sequence ensures selecve binding of Zn2+ ions and subsequent enzyme like behavior to realize catalyc amyloid.

Publicaons:

Ø Bhagwa Sharma, Ashmeet Singh, Tridib K.Sarma, Neha Sardana, Asish Pal Chirality control to mul-smuli responsive and self-healing supramolecular metallo- hydrogels, New J. Chem., 2018, 42, 6427-6432.

Ø Jojo P. Joseph, Ashmeet Singh, Asish Pal. Molecular Design Approaches to Self-healing Materials from Polymer and its nanocomposites in Smart Polymer Nanocomposites Energy Harvesng, Self-Healing and Shape Memory Applicaons; Springer Series on Polymer and Composite Materials, Springer, Switzerland 2017; pp 181-218.

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Awards/ Honors received: My students Mr.Ashmeet Singh received Malhotra Weikfield Foundaon Nanoscience Fellowship award at Bengaluru India Nano, 7-8 December, 2017

Sponsored projects: Ø PI: Smuli-responsive collapse of tailored single chain funconal polymer to diverse hierarchical nanostructures for catalysis and self-healing applicaons, DST-SERB. Ø PI: SANS study to probe collapse of the single chain polymer into discrete nanoparcles, UGC-DAE-CRS. Technology Developed/being developed, if any: Ø Surface modificaon of the texle fibers and beer adhesion to rubber will be result in a new technology to overcome the challenge of exisng convenonal resorcinol- formaldehyde method for SRF industries

4) Dr. Debabrata Patra, Scienst E Ongoing research interests/highlights: Enzymes provide high rate and selecvity during a chemical conversion, affording synthec route more economic and energy efficient compare to tradional organic synthesis. Despite the great potenal, the industrial applicaons of enzymes in biocatalysis have been restricted due to lack of long term stability, recovery and reusability. Recently enzyme immobilizaon on solid supports opens up an avenue which can overcome all those problems. It provides convenient handling of enzymes i.e. enzyme can be handled as a solid compare to liquid formulaon. In addion, it also offers easy separaon and prevents enzyme contaminaons. In this scenario, co-assembly of enzymes-nanoparcles (NPs) conjugates at liquid-liquid interface offers an elegant approach for enzyme immobilizaon and the immobilized enzymes show catalyc acvity. However this approach suffers from serious limitaons like size control of the microcapsules and leaching of enzymes from capsule wall, which in terms prevents the reusability of the microcapsules for biocatalysis.

Sponsored projects: Fabricaon of Reusable Biocatalyc Microcapsules using Microfluidic Device, DST-SERB-ECR Our research group focuses on high throughput producon of size-controlled microcapsules using microfluidic device. These microcapsules contains a solid core and enzymes are trapped on the wall of the microcapsules (Fig 1a). In this way we prevent enzyme leaching and thus improving the reusability. 48 Institute of Nano Science And Technology

We also fabricated dual catalyc microcapsules where both enzymes and nanoparcles are parcipang in catalysis (Fig 1b). Recently we started working on posioning mul-enzymes on emulsion templated microcapsules for cascade reacons. Figure 1: (A) Fabricaon of biocatalyc microcapsules using emulsion droplet. (B) One step formaon of dual catalyc microcapsules. Sponsored projects: Fabricaon of Reusable Biocatalyc Microcapsules using Microfluidic Device, DST-SERB-ECR 5) Dr. Jayamurugan Govindasamy, Scienst D

New synthec methods, Catalysis, Framework materials, supramolecular chemistry, Polymer

chemistry. The research in my group is centered on synthec organic chemistry with a view to exploring nanoporous and nanomaterials for various applicaons ranging from catalysis, Nano therapeucs, energy, drug delivery, and sensing, etc.

Research Highlights: Funconal Nano Materials in Drug Delivery:

Magnete funconalized nanoparcles aracted parcular interest as potenal drug delivery carriers as it offers the advantage of delivering drug to target site. In a joint collaboraon with biologist we successfully demonstrated for the first me that the development of a potenal drug carrier to improve the therapeuc efficacy of LCS-1 for specific killing of colorectal cells (CRC) having BLM defects (Figure 1).1,2 A customized Nano carrier (NC) composed of a magnete core coated with three polymeric shells, namely, aminocellulose, branched poly(amidoamine), and paraben-PEG, was synthesized and characterized for encapsulang LCS-1. Encapsulaon efficiency and drug loading were found to be 74% and 8.2%, respecvely.

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LCS-1-NC exhibited sustained release, with 85% of drug release in 24 h. Blank NC (0.5 mg/mL) exhibited cytocompability toward normal cells, mainly due to the AC layer. LCS-1-NC demonstrated high killing selecvity (104 mes) toward BLM-deficient HCT 116 cells over BLM- proficient HCT 116 cells. Due to enhanced efficacy of the drug using NC, the sensivity difference for BLM-deficient cells increased to 1.7 mes in comparison to that with free LCS-1.

Figure 1. Tailor-made magnete based nanocarrier for drug delivery. Nano science in Catalysis: Catalysis is another broad research area we are interested in study using nanomaterials. Herein, we show that copper oxide (CuI/IIO) nanoparcles (NPs) supported by tris-(2- amino ethyl)amine (TREN)-cellulose (TC) funconalized with thioglycolic acid TC-S-CuI/II O, showed excellent acvity for the homo- as well as cross-coupling of terminal alkynes to synthesize corresponding 1,3-diynes under eco-friendly condion (Figure 2). Unlike the popular CuAAC reacon invented by Sharpless and Meldel, Glaser–Hay cross-reacon does not enjoy the status of being “Click” reacon mainly due to its poor selecvity towards hetero-product, when two different terminal alkynes are used. In this work, we tried to address this issue.

GLASER COUPLING

+ OH

O TMEDA, 1:1 H2O/EtOH, 25 C

OH OH Additive Additive (72% yield) (75% yield) Non-Polar O COOH Polar Homo-Product Homo-Product HO ( ) 9 HOOC COOH No additive Medium Polar OH Hetero-Product (80% yield)

Figure 2. Polarity tuned selecvity of hetero Glaser reacon.

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Publicaons: Ø Gupta, A.; Ahmad, A .; Singh, H.; Kaur, S.; Neethu, K. M.; Ansari, M. M.; Jayamurugan, G.;* Khan, R.* Nanocarrier composed of magnete core coated with three polymeric shells mediates LCS-1 delivery for synthec lethal therapy of BLM-defecve colorectal cancer cells Biomacromolecules 2018, 19, 803–815. (*corresponding authors) Ø A Ahmad, A Gupta, G Jayamurugan,* R Khan,* Applying synthec lethality to nanomedicine: LCS-1 loaded magnete and polymeric nanoparcles for the treatment of BLM and CHEK2-deficient colorectal cancer cells. Cancer Medicine. Vol. 7. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY, 2018. Ø Jayamurugan, G.; Gowri, V.; Hernández, D.; Marn, S.; González-Orive, A.; Dengiz, C.; Dumele, O.; Pérez-Murano, F.; Gisselbrecht, J.-P.; Boudon, C.; Schweizer, W. B.; Breiten, B.; Finke, A. D.; Jeschke, G.; Bernet, B.; Ruhlmann, L.; Cea, P.; Diederich, F. Design and synthesis of Aviram-Ratner- type dyads and recficaon studies in Langmuir-Blodge (LB) films Chem. Eur. J.2016, 22, 10539–10547. Technology Developed/being developed: Highly efficient magnecally recyclable eco-friendly customized CuO nanoparcles catalyst for homo- and cross-Glaser reacons have been developed Sanconed Projects: a) Early Carrier Research Award (May 2016- May 2019), 24.14 Lakhs, funded by DST-SERB as PI. Project tle: Synthesis of a New Class of Strong Organic Acceptors and their Nanoparcles Formulaon for Sensing Applicaon. b) Research grant through Ramanujan Fellowship (May 2016 – May 2021), 35 Lakhs, funded by DST-SERB as PI. Project tle: Interconversion of Porous Covalent-Organic and Metal- Organic Frameworks for Versale Applicaons. c) DST-Nano Mission (Bio) project (July 2017 – July 2020) as joint-PI with Dr. Rehan has been approved for ~ 19.4 Lakhs. Project tle: “Synergisc Synthec Lethal Killing of Colorectal Cancer using Funconalized Nanomaterials” 6) Dr. Sangita Roy, Scienst C Our group focuses on design and development of new biofunconal nanomaterials based on sugar-pepde conjugates using molecular self-assembly approach. These supramolecular nanomaterial scaffolds are explored towards solving the problems of biology (e.g. drug delivery, cancer therapy, diagnoscs) and energy resources. More specifically, we are interested in: (a) developing molecularly- engineered biopolymer scaffolds to control the fate and commitment of stem cells towards the desired ssue (b) controlling the cell- e nv i ro n m e nt ( i n s o l u b l e a n d s o l u b l e components) interacons to understand stem cell biology (c) translate these fundamental understandings towards clinical applicaons in ssue engineering.

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Science & Technology, Projects, Administraon : Coordinator

Shri Mukesh Raja , Scienst C

Science & Technology, Administraon: Coordinator Administraon and Coordinaon Cell of INST undertakes all science and technology related maers like: Ø Research related collaborave projects between INST and other Instutes/Universies. Ø Preparaon of different Scienfic and techno-feasibility reports and their submission to different funding agencies like DST, DBT & CSIR and other grantee instuons. Follow up acon for INST acvies. Ø Nodal point of INST for the Chandigarh Region Innovaon and Knowledge Cluster (CRIKC). Ø R&D Projects Management Ø Preparaon of Annual Report of INST. Ø Results-Framework Document (RFD). Ø Parliament Quesons Ø Furnishing of inputs on various subject as sought by DST from me to me. All above Scienfic acvies and any other miscellaneous work looked aer by this cell.

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8) Some of Research Highlights:

1) DNA Origami Directed Au Nanostar Dimers for Single-Molecule Surface-Enhanced Raman Scaering (Swa Tanwar, Krishna Kanta Haldar and Tapasi Sen*J Am Chem Soc 2017, 139, 17639). Dr. Tapasi Sen and her group have recently designed Au nanostar dimers with precisely tunable interparcle gap and controlled stoichiometry assembled on DNA origami. They have immobilized Au nanostars with uniform and sharp ps on rectangular DNA origami dimerized structures. The SERS enhancement factors of single Texas red dye molecules placed in the centre of dimeric structures having interparcle gaps of 7 and 13 nm are 2 × 1010 and 8 × 109, respecvely,which are strong enough for single analyte detecon. The highly enhanced electromagnec field generated by the coupling of sharp ps of Au nanostars exhibits excellent SERS sensivity in the wide conjuncon region that allows the accommodaon and specific detecon of large biomolecules. Such DNA- directed assembled nanoantennas with controlled interparcle distance and stoichiometry, can be used as excellent substrates in single-molecule SERS spectroscopy and will have potenal applicaons as a cost-effecve and reproducible plaorm in single- molecule sensing. 2) Correlang Charge Carrier Dynamics with Efficiency in Quantum Dot Solar Cells: Can Excitonics Lead to Highly Efficient Devices? (J. Dana, S. Mai, V. S. Tripathi. and Hirendra N. Ghosh*, Chem. Eur. J., 2018, 24, 2418–2425) The photovoltaic performance of quantum dot solar cells strongly depends on the charge carrier relaxaon and recombinaon processes which need to be modulated in a favourable way to obtain maximum efficiency. Recently, we have significantly devoted our efforts to invesgate the carrier dynamics of nanocrystal sensizers both in soluon phase and upon deposited on TiO2 photoanode with the aim to correlate the excitonics with solar energy conversion efficiency. We have demonstrated some proof-of-the concept that efficiency can be directly correlated with the exciton dynamics for quantum dot solar cells. Our findings are based on CdSeS alloy, CdSe/CdS core/shell, Au/CdSe nano-hybrids and Mn-doped CdZnSSe nanocrystals where we opmize the favourable excitonic processes to enhance the efficiency. Lastly, we have also suggested the future prospects and limitaons that need to be addressed in future. 53 Institute of Nano Science And Technology

3) Long-range ferrimagnec order in a two-dimensional supramolecular Kondo lace, (Girovsky J, Nowakowski J, Ali ME, et al., Nat. Commun. 2017, 8, 15388). Dr. Ehesan Ali in collaboraon with Uppsala University, Paul Scherrer Instute and IISER-Pune invesgated the long-range ferromagnec ordering on surface supported two-dimensional system of MnPc (Mn-phthalocyanine) and FeFPc that were deposited on 2x2 checkers board paern on Au(111) substrate. The magnec centers are apart from each other by 14.35 Å, but the ferrimagnec interacons are rather strong. Applying on- site coulomb correlaons corrected DFT+U method the nature and strength of the exchange interacons were computed. It was further observed that a substanal overlap between the 3dz2 orbital of the manganese and Au(111) substrate charge density. To determine the origin of the ferrimagnec coupling they performed addional calculaons removing the Au substrate. In absence of the Au substrate, the magnec moments on the metal centers orient randomly. It indicates that the molecule–molecule spin coupling is not due to a weak exchange interacon mediated by the overlap of phthalocyanine ligands. Rather, the electrically conducve MnPc and FeFPc are co-adsorbed on Au(111).Side view and top view. Au(111) substrate is pivotal for mediang the magnec interacon between FeFPc and MnPc following the RKKY type of interacons.

4) Strain and pH facilitated arficial photosynthesis in monolayer MoS2 nanosheet (Dimple, Nityasagar Jena, Ashima Rawat and Abir De Sarkar*, J Mat Chem A 2017, 5, 22265). Dr. Abir De Sarkar and his group have demonstrated the ease of applying mechanical strain reversibly in low dimensional materials and its ulity in opmizing their arficial photosynthec properes. Photo conversion of carbon dioxide with water into renewable solar fuels using a single integrated system is the primary goal of arficial photosynthesis. Strain effects on the concerted interplay of all the factors controlling the photocatalyc ability, such as suitable band edges straddling the redox potenals for CO2 reducon with water and oxygen evoluon reacons, opcal absorbance and conducvity, carrier mobilies, carrier mobility raos and exciton binding energies, have been comprehensively studied on monolayer MoS2 nanosheets and calibrated, using density funconal theory, to ascertain the type and magnitude of strain under which the opcal absorbance and conducvity, carrier mobilies and the carrier mobility rao are simultaneously and opmally enhanced, while the requisite redox reacvity and small exciton binding energies are retained. 54 Institute of Nano Science And Technology

5) Large area few-layer graphene with scalable preparaon from waste biomass for high- performance supercapacitor, (Taniya Purkait, Guneet Singh, Mandeep Singh, Dinesh Kumar & Ramendra Sundar Dey*, Sci. Rep. 2017, 7, 15239). Dr. Ramendra Sundar Dey and his group have recently developedfew-layer graphene- likenanosheets with abundance of micro as well as mesopores from an agricultural waste biomass: peanut shell.The objecve of the work is to aempts not only to solve the age-old socio-economic issue of waste recycling but also to generate value-added materials like conducve graphene from wastes, for renewable energy s t o r a g e d e v i c e s l i k e supercapacitors. The method i s b i o c o m p a b l e a n d

reproducible at the industrial scale.The Peanut shell- derived grapheane possesses remarkablyHigh surface area (2070 m2 g−1) and sheet-like structure promotes fast ion-transport kinecs, making them an ideal choice to be used in supercapacitors.The highest energy density of 58.125 W hKg−1 and highest power density of 37.5 W Kg−1 was achieved by the material.Solid-state- supercapacitor was fabricated with this material for the possible use of low-cost,high-energy promising energy storage device. 6) Excellent Humidity Sensor based on In-SnO2 Loaded Mesoporous Graphic Carbon Nitride (Malik, R.; Tomer. V. K.*; Chaudhary, V.; Dahiya, M. S.; Nehra, S. P.; Duhan, S.; Kailasam, K.* J. Mater. Chem. A 2017, 5, 14134-14143). Dr. Kamalakannan and his group have demonstrated the synthesis and sensing performance of In-SnO2/meso-CN nanohybrid for next generaon humidity sending applicaons. The sensor is highly sensive and fast responsive to relave humidity (%RH). They showed superfast response (3.5 s) and recovery (1.5 s) in 11-98 %RH range at room temperature. Repeated response and recovery curves for In-SnO2/meso-CN was measured in 5 loops in 11-98 %RH r a n g e a n d s h o w s s i m i l a r impedence values, which reveals t h a t t h e r e s p o n s e o f I n - SnO2/meso-CN sensor is highly reversible. These results open the door for breath monitoring and shows promising glimpse for designing mesoporous 2D layered materials in the development of futurisc ultrasensive %RH sensors.

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9) Funding @ INST

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Projects Sanctioned to INST: Sr. Title of the Project Funding Agency 2014-15 Development of Versale, Mulfunconal and Adaptable Pepde Nanofiber Scaffolds 1. with Potenal for Promong Neurogenesis in Brain Injury and Stroke, Dr Jiban Jyo DST INSPIRE Panda 2. Smart Gels for Green Energy Applicaons, Dr. Sangita Roy SERB-YSS First-Row Transion Metals in Catalyc Atom/Group - Transfer Funconalizaon of 3. Hydrocarbons, Dr. Vivek Bagchi SERB-YSS 4. Self- Assembled nano structures for photocatalyc applicaons, Dr. S. Vaidya SERB-YSS 5. Smart packing system with the nanocomposite to improve the shelf life of perishable CARS, DIHAR vegetable, Dr. PS Vijaya Kumar and Dr. Sonalika Vaidya 6. Metered dose trans-dermal nano-spray herbal gel formulaon for rapid relief and CARS, DIHAR effecve management of cold injury at extreme altudes, Dr. Rahul Kumar Verma 2015-2016 Design of controlled and targeted agricultural pescide delivery nano-carrier with DST Nano 1. copper-graphene oxide composite, Dr. P S Vijaya Kumar and Dr. Vivek Bagchi Mission Nanostructured Materials Synthesized from Transion Metal, Dr. Vivek Bagchi, Prof. A,K. SERB-EMR 2. Ganguli and Dr. Sonalika Vaidya Pulmonary delivery of Host Defence Pepdes (HDP) using Porous nanoparcle- 3. Aggregate Parcles (PNAPs) for alveolar macrophage targeng in pulmonary SERB-YSS tuberculosis, Dr. Rahul Kumar Verma Magneto-opto-electronic properes and applicaons of 2-dimensional electron gas DST Nano 4. system at oxide interfaces, Dr. Suvankar Chakraverty, Prof. A,K. Ganguli,Dr. Kiran Shankar Hazra, Dr. Kaushik Ghosh, Dr. Chandan Bera and Mr. Bhanu Prakash Mission Cell Free Bioreactors from the Shell Proteins of Bacterial Microcompartments, Dr. 5. Sharmishtha Sinha DST-EMR 6. Idenficaon of polycomb and c-Myb signaling and their targeted nanotherapy in SERB-YSS leukemogenesis, Dr. Subhasree Roy Choudhury 7. Nanoporous materials for carbon dioxide sequestraon, Dr. Monika Singh SERB-YSS Towards the development of hybrid supercapacitor-biofuel cell technology and devices, 8. Dr. Ramendra Sundar Dey DST INSPIRE Nanoparcle-mediated inhibion of PRDX2 for selecve killing of CHEK2-defecve 9. colorectal cancer cells by synthec lethality, Dr. Rehan Khan SERB-YSS 10. Bio-mimicking photocatalyc water oxidaon using Manganese and Cobalt oxide SERB-ECR nanomaterials: understanding the effect of redox nacve metal ion, Dr. Sanyasinaidu Boddu 2016-2017 1. Synthesis and Photophysical Study of New Class of Push-Pull Chromophores for DST Ramanujan Optoelectronic Applicaons, Dr. Jayamurugan Govindasamy Smuli-responsive collapse of tailored single chain funconal polymer to SERB-ECR 2. diverse hierarchical nanostructures for catalysis and self-healing applicaons, Dr. Asish 3. Photomagnec Control of Molecular Spintronic Properes, Dr. Ehesan Ali SERB-ECR

4. Synthesis of a New Class of Strong Organic Acceptors and their Nanoparcles SERB-ECR Formulaon for Sensing Applicaon, Dr. Jayamurugan Govindasamy 5. Organoboron Macrocycles as Adaptable, Photoacve Materials, Dr. Prakash P. SERB-ECR Neelakandan

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Assessment of maternal, reproducve and fetal toxicity induced by intrauterine 6. exposure of carbonaceous nanomaterials like graphene and carbon nanotubes, Dr. SERB-YSS Manish Singh New class of flexible solid-state supercapacitor from nano-engineered carbonaceous 7. materials, Dr. Ramendra Sundar Dey and Dr. Kaushik Ghosh DST EMR

Design, Growth and Invesgaon of New Mulferroic materials, Prof. Ashok K Ganguli 8. and Dr. Suvankar Chakraverty SERB EMR

Plasmonic enhancement of single molecule fluorescence by metallic nanoantennas 9. assembled on DNA origami, Dr. Tapasi Sen SERB-ECR

Search of new materials showing exoc superconducng and magnec properes in 10. bulk and mesoscale, Prof. Ashok K Ganguli and Dr. Kiran Shankar Hazra SERB-EMR

Nanotherapy for controlling epigenec regulaon by polycomb in Myb mediated 11. leukemia, Dr. Subhasree Roy Choudhury and Dr. Surajit Karmakar DBT 12. Tailorable plasmonic metamaterial substrates : Gold and beyond, Dr. Neha Sardana SERB-ECR Low cost diagnosc system for public health surveillance targeng bacterial enteric DST-Nano 13. pathogens, Dr. Priyanka, Prof. Ashok Ganguli, Dr. Vivek Bagchi, Mr. Bhanu Prakash and Mission Dr. Neha Sardana

Photocatalyc-driven Hydrogen Generaon and Cellulosic-Biomass Conversion using 14. Mesoporous Carbon Nitrides, Dr. Kamalakannan Kailasam SERB-ECR Prototype Reactor for Simultaneous Producon of H2 and Fine Chemicals under DST-Nano 15. Natural Sunlight, Dr. Kamalakannan Kailasam, Prof. A.K. Ganguli, Dr. Vivek Bagchi, Dr. Prakash Neelakandan, Dr. Menaka Jha Mission 16. Computaonal study of spin polarizaon in ternary chalcogenide, Dr. Chandan Bera SERB-EMEQ DAE-UGC 17. SANS study to probe the collapse of Single Chain Polymer in to discrete Nanoparcles, Dr. Asish Pal CSR SERB Women 18. Cellulose-protein binary conjugates for metal detoxificaon, Dr. Sharmistha Sinha Excellence Award Exploring the Shell Proteins of BMCPs as Potenal Substrates for Fabricaon of Organic- DST-Nano 19. Inorganic Hybrid Nanomaterials, Dr. Sharmistha Sinha, Dr. Eehsan Ali and Dr. Neha Sardana Mission Dual-Drug loaded Customized Nanocarrier for Synergisc Synthec Lethal Killing of DST-Nano 20. Colorectal Cancer. Dr. Rehan Khan & Dr. Jayamurugan Govindasamy Mission Dynamic self-assembled nucleic acid analogues, Dr. Prakash P. Neelakandan and 21. Dr. Asihan Shanavas DBT Surface modificaon for beer adhesion property between Rubber and texles, 22. Dr. Sangita Roy, Dr. Jayamurugan Govindasamy, Prof. A.K. Ganguli and Dr. Ashish Pal SRF Ltd

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2017-18 Sr. Title of the Project/Scheme Funding Agency Prototype Reactor for Simultaneous Producon of H2 and Fine Chemicals under Natural DST-Nano 1. Sunlight, Dr. Kamal Mission-NATAG Biomass Derived Nanostructured Cellulose Aerogel Materials for Thermal Insulaon in 2. Energy Efficient Smart Buildings,Dr. Kamal DST-CERI Mulmodal Glioblastoma Therapy by Blood Brain Barrier Traversing and Glioma DBT 3. Targeng An-cancer Pepde Theranosc Nanoparcles Dr. Jiban Jyo Panda Bio-care Low temperature growth of carbonaceous heterostructure for magnec and thermal DST-Nano 4. applicaon, Dr. Kaushik Ghosh Mission Dual-Drug loaded Customized Nanocarrier for Synergisc Synthec Lethal Killing of DST-Nano 5. Colorectal Cancer., Dr. Rehan Khan & Dr. Jayamurugan Govindasamy Mission Reconstutable Lyophilized Plasmonic Semishells as Near Infra Red Photothermal 6. Nanotransducers for Cancer Treatment, Dr. Asif Khan DBT Fabricaon of Reusable Biocatalyc Microcapsules using Microfluidic Device, Dr. SERB-ECR 7. Debabrata Patra Gold capsuled combinaon nanomedicine for target specific therapy of chemoresistant SERB-EMR 8. breast tumors, Dr. Asihan Shanavas In Silico Studies of Magnec and Vibraonal Properes of Porphyrins for Diagnosc DST-DAAD 9. Applicaons , Dr. Ehesan Ali 10. Dynamic self-assembled nucleic acid analogues,Dr. Prakash P. Neelakandan DBT

Atomic-scale invesgaon of the nanopiezotronic properes in semiconducng DST-Nano 11. transion metal dichalcogenide monolayers via first-principles electronic structure methods, Dr. Abir De Sarkar Mission Computaonal predicon of novel thermoelectric nanomaterials Dr. Chandan Bera 12. SERB-EMR Air Purificaon Device for Harmful Pollutant and VOC Sequestraon: Economical and 13. Reusable, Dr. Vivek Bagchi DST-TDP A high performance nanodelivery system for Inflammatory Bowel Disease (IBD) therapy, 14. Dr. Surajit Karmakar SERB-ECR Enzyme acvated targeted nano-formulaons of autophagy/apoptosis-inducing agents DST-Nano 15. as potenal therapy for drug resistant lung cancerDr. Rahul Kumar Verma Mission Encapsulaon of pescides by Magnec nanoparcles coated with polysaccharides to DST Women 16. improve the input delivery,Dr. Ritu Mahajan Scienst Exploring the Shell Proteins of BMCPs as Potenal Substrates for Fabricaon of Organic- DST-Nano 17. Inorganic Hybrid Nanomaterials, Dr. Sharmistha Sinha Mission Temozolomide delivery across blood-brain barrier through nanomagnec transducer: A 18. targeted therapy for Glioblastoma mulforme,Dr. Deepika Sharma SERB-ECR 19. Fabricang rGO based highly sensive non-cryogenic micro-bolometer sensor array for thermal imaging applicaons, Kiran S Hazra SERB-EEQ 20. Surface modificaon for beer adhesion property between Rubber and texles,Dr. Sangita Roy SRF Ltd 21. Method development for measurement of thermal properes (especially thermal conducvity) for heat transfer materials at higher temperature, Dr Chandan Bera IOCL 22. Extracon of nanostructured materials from gaseous effluents of power plants,Dr. Menaka Jha NTPC 23. Development of Prototype for Removal of Toxic Impurity from Waste Water Dr. Menaka Jha INST 59 Institute of Nano Science And Technology

10) Publicaons and INST: a) Publicaons (2017-18) :

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2018 Sr Title of Research paper 1. Plasmonic DNA hotspots made from Tungsten disulfidenanosheets and gold nanoparcles for ultrasensive aptamer-based SERS detecon of Myoglobin, M. Shorie, V. Kumar, H. Kaur, K. Singh, V. K Tomer, P. Sabherwal, Microchimica Acta.2018, 185:158

2. New Insight into Curcumin Tethered Lanthanum Carbonate Nanospheres and Protein Corona Conferring

Fluorescence Enhancement based Sensive Detecon of Amyloid- Aggregates, Anup K. Srivastava , Atul Dev, Subhasree Roy Choudhury SurajitKarmakar, Sensors and Actuators B:Chemical 2018 262, 687-695 3. Organo-lead halide per ovskite induced electroacve β-phase in porous PVDF films: An excellent material for photoacve piezoelectric energy harvester and photodetector, A. Sultana, P. Sadhukhan, Md. M. Alam, S. Das, T. R. Middya and D. Mandal, ACS Appl. Mater. Interfaces 2018, 10, 4 121–4130. 4. Synthec lethality: From Research to Personalized Cancer Nanomedicine, A. Gupta, A. Ahmad, A.I. Dar, R. Khan*, Current Cancer Drug Targets 2018. 2018;18(4):337-346 5. Nanocarrier Composed of Magnete Core Coated with Three Polymeric Shells Mediates LCS-1 Delivery for Synthec Lethal Therapy of BLM-Defecve Colorectal Cancer Cells, A. Gupta, A. Ahmad, H. Singh, S.

Kaur, Neethu K M, M. M. Ansari, G. Jayamurugan* and R. Khan*, Biomacromolecules 2018, 19, 803-815. 6. Cellulose-Metallothionein Matrix for Metal Binding, N. K.Baria, S. Baruaa, A. Garga, M. K.Sannigrahi and

S. Sinha*, Carbohydrate Polymers. 2018, 192, 126-134. 7. Chirality control to mul-smuli responsive and self-healing supramolecular metallo-hydrogels, B Sharma, A. Singh, T. K. Sarma, N. Sardana* and A. Pal*, New J ournal of Chemistry 2018,42, 6427-6432. 8. Twin Funcon of Zein−Zinc Coordinaon Complex: Wheat Nutrient Enrichment and Nanoshield against Pathogenic Infecon., B. K. Biswal, M. El Sadany, D. Kumari, P. Sagar, N. K. S inghal, S. Sharma, T. Stobdan and S. Vijayakumar*, ACS Sustainable Chem. Eng. 6, 5877–5887. 9. A comprehensive study in carrier mobility and arficial photosynthec properes in Group VI B transion metal dichalcogenide monolayers, A. Rawat, N. Jena, Dimple, A. D . Sarkar.*, Journal of Materials Chemistry A. 2018, 6, 8693-8704

10. Reclaiming Hijacked Phagosomes: Hybrid Nano-in-Micro encapsulated MIAP pepde ensures host directed therapy by specifically augmenng phagosome-maturaon and apoptosis in TB infected

macrophage cells. Sharma, A, Vaghasiya, K, Gupta P, Gupta U D and Verma, R.K., Internaonal Journal of Pharmaceucs(Accepted) 11. Glycol Chitosan assisted in situ Reducon of Gold on Polymeric Template for An-cancer Theranoscs, A. Shanavas, A. K. Rengan, D. Chauhan, L. George, M. Vats, N. Kaur, P. Yadav, P. Mathur, S. Chakraborty, A. Tejaswini, A. De, R. Srivastav a. 2017, Internaonal Journal of Biological Macromolecules, In Press. DOI: 10.1016/j.ijbiomac.2017.11.127 12. High-performance flexible supercapacitors based on electrochemically tailored three-dimensional reduced graphene oxide networks, T. Purkait, G. Singh, D. Kumar, M. Singh and R. S. Dey , Sci. Rep., 2018, 8, 640.

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13. PHISTc p rotein family members localize to different sub-cellular organelles and bind Plasmodium falciparum major virulence factor 'PfEMP-1', Kumar V, Kaur J, Singh AP, Singh V, Bisht A, Panda JJ, Mishra PC, Hora R., FEBS J. 2017 Nov 20. doi: 10.1111/febs.14340 14. Targeted delivery of miR-199a-3p using self-assembled dipepde nanoparcles efficiently reduces hepatocellular carcinoma, Varshney A, Panda JJ, Singh AK, Yadav N, Bihari C, Biswas S, Sarin SK, Chauhan

VS., Hepatology. 2017, Nov 6. doi: 10.1002/hep.29643

15. Arginine-α, β-dehydrophenylalanine Dipepde Nanoparcles for pH-Responsive Drug Delivery., Singh

PK, Chibh S, Dube T, Chauhan VS, Panda JJ, Pharm Res. 2018 Jan 16;35(2):35. doi: 10.1007/s11095-017- 2299-8. 16. Realizao n of single terminated surface of perovskite oxide single crystals and their band profile: (LaAlO3)0.3(Sr2AlTaO6)0.7, SrTiO3 and KTaO3 case study, R. Tomar, N. Wadehra, V. Budhiraja, B. Prakash, S.Chakraverty, Applied Surface Science 2018, 427, 861-866. 17. Gold laced Bio-macromolecules for theranosc applicaons, P. Yadav, S. P. Singh, A. K. Rengan, R. Srivastava, A. Shanavas, Internaonal Journal of Biological Macromolecules, 2018, 110, 39-53. 18. Synthec Diversity and Luminescence Property of ArN(PPH2)2 based Copper (I) complexes, Kathewad, N.; Pal, S.; Kumawat, R. L.; Ali, Md. E.; Khan, S, Eur. J. Inorg. Chem. 2018 (accepted)

19. Supramolecular Confinement within Chitosan Nanocomposites Enhances Singlet Oxygen Generaon,

Khalid Naim, Sreejisha T. Nair, Pranjali Yadav, AsihanShanavas, and Prakash P. Neelakandan,

ChemPlusChem 20. Mannose-conjugated curcumin-chitosan nanoparcles: Efficacy and toxicity assessments against Leishmaniadonova ni, Chaubey P, Mishra B, Mudavath SL, Patel RR, Chaurasia S, Sundar S, Suvarna V, Monteiro M, Int J BiolMacromol, 111:109-120

21. Modulang Capacitive Response of MoS2 Flake by Controlled Nanostructuring through Focused Laser Irradiaon, R.Rani, A.Kundu, Mohammad Balal , Goutam Sheet and Kiran Shankar Hazra, Nanotechnology, 2018 22. One-step coelectrodeposion-assisted layer-by-layer assembly of gold nano parcles and reduced graphene oxide and its self -healing three-dimensional nanohybrid for an ultrasensive DNA sensor, J Kumarasamy, MB Camarada, D Venkatraman, H Ju, R. S. Dey, Y Wen, Nanoscale 10 (3), 1196 -1206

23. Characterizaon of Cd-resistant Klebsiellamichiganensis MCC3089 and its potenal for rice seedling growth promoon under Cd stress, S Mitra, K Pramanik, PK Ghosh, T Soren, A Sarkar, R. S. Dey, S Pandey, T. K. Mai, Microbiological research 210, 12-25 24. Boosng the Efficiency of Quantum Dot Solar Cells Through Formaon of Caon Exchanged Hole Transporng Layer, S. Mai, F. Azlan, P. Anand, Y. Jadhav, J. Dana, S. K. Haram and H. N. Ghosh*, Langmuir, 2018, 34, 50–57. 25. Concurrent Ultrafast Electron and Hole Transfer Dynamics in CsPbBr3 Perovskite and Quantum Dots, J. Dana, P. Maity, B. Jana, S. Mai, and Hirendra N. Ghosh*, ACS Omega, 2018, 3, 2706-2714. 26. Solar Conversion Efficiency Pe rformance of High Temperature Grad ient Alloy over Low Temperature One: Comprehending Interfaces through Excitonics Study, T. Debnath, K. Parui, S. Mai, H. N. Ghosh*, J. Phys. Chem. C, 2018, 122 (21), pp 11312–11321

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27. Modified surfaces using seamless graphene/carbon nanotubes based nanostructures for enhancing pool boiling heat transfer, GU Kumar, K Soni, S Suresh, K Ghosh, MR Thansekhar, PD Babu, Experimental Thermal and Fluid Science 96, 493-506 28. 1,3β Glucan anchored, paclitaxel loaded chitosan nanocarrier endows enhanced hemocompability with efficient an-glioblastoma stem cells therapy, Singh PK, Srivastava AK, Dev A, Kaundal B, Choudhury SR*, Karmakar S., CarbohydrPolym. 2018

29. Solar Conversion Efficiency Performance of a High Temperature Alloy over a Low Temperature One:

Comprehending Interfaces through Excitonics Study, T. Debnath, K. Parui, S. Mai, H. N. Ghosh*, J. Phys. Chem. C, 2018,122, 11312−11321. 30. Correlang Charge Carrier Dynamics with Effici ency in Quantum Dot Solar Cells: Can Excitonics Lead to Highly Efficient Devices? , S. Mai, J. Dana, and Hirendra N. Ghosh*, Chem. Eur. J., 2018, (Mini Review) (ASAP) MS No: chem.201801853 31. Hot Charge Carrier Extracon from Semiconductor Quantum Dots: A Step toward High Efficiency Quantum Dot Solar Cell, PallaviSinghal, and Hirendra N. Ghosh*, J. Phys. Chem. C, (Feature Arcle) 2018, ASAP, MS No: acs.jpcc.8b03980. 32. A Low Temperature, Highly Sensive and Fast Response Toluene Gas Sensor Based on In(III) -SnO2 Loaded Cubic Mesoporous Graphic Carbon Nitride, R. Malik, V. K. Tomer*, V. Chaudhary, M. S. Dahiya,

S. P. Nehra, S. Duhan and K. Kailasam*, Sens. Actuators B, 2018, 255, 3564-3575 33. Traversing the History of Solid Catalysts for Heterogeneous Synthesis of 5 -Hydroxymethylfurfural from Carbohydrate Sugars: A Review, B. Agarwal, K. Kailasam, R. S. Sangwan* and S. Elumalai *, Renewable and Sustainable Energy Reviews,2018,82, 2408–2425. 34. Natural sunlight driven oxidave homocoupling of amines by truxene based conj ugated microporous polymer, V. R. Baula, H. Singh, S. Kumar, I. Bala, S. K. Pal* and K. Kailasam, ACS Catalysis,2018,8, 6751- 6759 35. Hydrogen-bond mediated columnar liquid crys talline as semblies of C3 -symmetric heptazine derivaves at amb ient temperature, I. Bala, S. P. Gupta, S. Kumar, H. Singh, J. De, N. Sharma, K. Kailasam* and S. K. Pal*, So Maer, 2018, DOI: 10.1039/c8sm00834e 36. Deep-Blue OLED Fabricaon from Heptazine Columnar Liquid Crystal Based AIE-Acve Sky Blue Emier, I. Bala, L. Ming, R. A. K. Yadav, J. De, D. K. Dubey, S. Kumar, H. Singh, J. –H. Jou, K. Kailasam, and S. K.

Pal*, Chemistry Select,2018, 3, 7771–7777 37. Emergence of s-Heptazines: From trichloro-s-heptazine building blocks to funconal materials, S. Kumar, N. Sharma and K. Kailasam, Journal of Materials Chemistry A, 2018, DOI: 10.1039/C8TA05430D

38. Hollow ZnO from assembly of nanoparcles: photocatalyc and anbacterial acvity, Z Zaidi, K Vaghasiya, A Vijay, M Sharma, RK Verma, S Vaidya, Journal of Materials Science,(2018). h ps://doi.org/10.1007/s10853-018-2715-4 39. Growth of highly crystalline and large scale monolayer MoS2 by CVD: The role of substrate posion, Kumar, N.; Tomar, R.; Wadehra, N.; Devi, M. M.; Prakash, B.;* Chakraverty, S.Ϯ, Cryst. Res. Technol. 2018, 1800002

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40. Droplet-microfluidics for the controlled synthesis and efficient photocatalysis of TiO2 nanoparcles, Baruah, A.; Singh, A.; Sheoran, V.; Prakash , B.;* Gang uli, A. K.Ϯ; ,Mater . Res. Express, 2018, 5, 7. 41. Connuous flow synthesis of Ag3PO4 nanoparcles with greater photostability and photocatalyc dye degradaon efficiency, Astha Singh, ArabindaBaruaha, VibhavKatocha, Kalpesh Vaghasiyaa, BhanuPrakasha, Ashok K. Ganguli, J. Photochem. Photobiol A, 2018, 364, 382.

42. All-Organic High-Performance Piezoelectric Nanogenerator with Mullayer Assembled Electrospun

Nanofiber Mats for Self-Powered Mulfunconal Sensors, K. Maity and D. Mandal, ACS Appl. Mater. Interfaces 2018, 10, 18257−18269 43. A Pyroelect ric Generator as a Self-p owered Temperature Sensor for Sustainable Thermal Energy Harvesng from Waste Heat and Human Body Heat, A. Sultana, Md. M. Alam, T. R. Middya and D. Mandal, Applied Energy 2018 221, 299 – 307 44. An Efficient Wind Energy Harvester of Paper As h-Mediate Rapidly Synthesized ZnO Nanoparcle- Interfaced Electrospun PVDF Fiber, Md. M. M. Alam, S. K. Ghosh, A. Sultana, and D. Mandal, ACS Sustainable Chem. Eng.(IF~6.1), 6, 292–299 45. Nanoparcle Fabricaon on Bacterial Microcompart ment Surface for the Development of Hybrid Enzyme-Inorganic Catalyst, NaimatKalim Bari, Gaurav Kumar, Aashish Bha, Jagadish Prasad Hazra,

Ankush Garg, Md. Ehesan Ali, Sharmistha Sinha, ACS Catalysis , DOI: 10.1021/acscatal.8b02322 46. Superior Bactericidal Efficacy of Fucose-Funconalized Silver Nanoparcles against Pseudomonas

aeruginosa PAO1 and Prevenon of Its Colonizaon on Urinary Catheters, Arpit Bhargava, VikramPareek,Subhasree Roy Choudhury, JitendraPanwar , and SurajitKarmakar , ACS Ap pl. Mater. Interfaces , 2018, 10 (35), pp 29325–29337, DOI: 10.1021/acsami.8b09475 47. Pathway Driv en Self-assembly and Living Supramolecular Polymerizaon in Amyloid -inspired Pepd e Amphiphile, Ashmeet Singh , Jo jo Joseph, Deepika Gupta, Indr anil Sarkar, Asish Pal*, Chem Comm, DOI: 10.1039/C8CC06266H 48. Biomechanical and acousc energy harvesng from TiO2 nanoparcle modulated PVDF nanofiber made high performance nanoge nerator, Md. M. M. Alam , A. Sultana, D. Sarkar and D. Mandal*, ACS Appl. Energy Mater. 1 (7), 3103–3112.

49. Synergiscally enhanced piezoelectric output in highly aligned 1D polymer nanofibers integrated all- fibernanogenerator for wearable nano-tacle sensor, S. K. Ghosh and D. Mandal*, Nano Energy

hps://doi.org/10.1016/j.nanoen.2018.08.036 50. Organo-lead Halide Perovskite Regulated Green Light Eming Poly (vinylidene fluoride) Electrospun Nanofiber Mat and its Potenal Ulity for Ambient Mechanical Energy Harvesng Applicaon, A. Sultana. M. Alam, P. Sadhukhan, U, K, Ghorai, S, Das , T. R. Middya, D. Mandal, Nano Energy. 2018, 49, 380-392. 51. Direct Correlaon of Excitonics with Efficiency in Core Shell Quantum Dot Solar Cell., J. Dana, S. Mai, V. S. Tripathi. and Hirendra N. Ghosh, Chem. Eur. J., 2018, 24, 2418-2425 52. Inhibing Interfacial Charge Recombinaon for Boosng Power Conversion Efficiency in CdSe{Au} Nanohybrid Sensized Solar Cell., J. Dana, P. Anand, S. Mai, F. Azlan, Y. Jadhav, S. K. Haram, H. N. Ghosh, J. Phys. Chem. C, 2017, 121, ASAP. DOI: 10.1021/ acs.jpcc.7b08448

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53. Connuous flow synthesis of Ag3PO4 nano parcles with greater photostability and photocatalyc dye degradaon efficiency, AsthaSingha,ArabindaBaruaha, ,Kalpesh Vaghasiya, Bhanu Prakash, Ashok K. Ganguli, Journal of Photochemistry and Photobiology A: ChemistryVolume 364, Pages 38 2-389 54. Microemulsion based approach for nanospheres assembly into anisotropic nanostructures of NiMnO3 and their magnec properes, MenakaJha, Sandeep Kumar, Neha Garg, Kandalam V.

Ramanujachary, Samuel E. Lofland, Ashok K.Ganguli, Journal of Solid State Chemistry, Volume 258, February 2018, Pages 722-727 55. Transf ormaon of waste n-plated steel to iron nanosheets and their applicaon in generaon of oxygen, Manolata Devi, KasinathOjha, Ashok K. Ganguli, MenakaJha, Internaonal Journal of Environmental Science and Technology, pp 1–10 56. Room temperature synthesis of urea based imid azole funconalised ZnOnanorods and their photocatalyc applicaon, Jayan Mishra, MenakaJha, Navneet Kaur,Ashok K. Ganguli, Materials Research Bullen, Volume 102, June 2018, Pages 311-318 57. Aptamer funconalized MoS2-rGO nanocomposite based biosen sor for the detecon of Vi angen, PreeKumariPathania,Jai KumarSaini,Shania Vij,RupinderTewari,Priyanka Sabherwal, Praveen Rishi, C. Raman Suri, Biosensors and Bioelectronics 58. Nano-encapsulated HHC10 host defense pepde (HDP) reduces the growth of Escherichia coli via

mulmodal mechanisms, AnkurSharma,KalpeshVaghasiya,Eupa Ray &Rahul Kumar Verma, Arficial Cells, Nanomedicine, and Biotechnology 59. Effect of ionic size compensaon by Ag+incorporaon in homogeneous Fe-sub stuted ZnO: studies on structural, mechanical, opcal, and mag nec properes, Gaurav Bajpai, Tulika Srivastava, N. Patra, IgamchaMoirangthem, S. N. Jha, D. Bhaacharyy, Sk Riyajuddin, Kaushik Ghosh, Dharma R. Basaula, Mahmud Khan, Shun-Wei Liu, SajalBiring, Somaditya Sen, RSC Adv., 2018, 8, 24355 -24369 60. New lo w temperature process for stabiliza on of nanostructur ed La2NiMnO6an d their magnec properes , Vishwajit M. Gaikwad, Krish na K. Yadav, S.E. Lofland, Kandalam V. Ram anujachary, SuvankarChakraverty, Ashok K. Ganguli, MenakaJha, Journal of Magnesm and Magnec Materials 61. Comparave Nitrene-Transfer Chemistry to Olefinic Substrates Mediated by a Library of Anionic Mn(II)

Triphenylamido-Amine Reagents and M(II) Congeners (M = Fe, Co, Ni) Favoring Aromac over Aliphac

Alkenes, VivekBagchi, AnshikaKalra, Purak Das, PatrinaParaskevopoulou, Saidulu Gorla, Lin Ai, Qiuwen Wang, SudipMohapatra, Amitava Choudhury, Zhicheng Sun∥, Thomas R. Cundari, Pericles Stavropoulos, ACS Catal., 2018, 8, pp 9183–9206 (ll publicaons of thi s report)

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11) Lecture at INST Mohali: a) Invited Lectures: Dated By Topic Organic-inorganic hybrid perovskite materials for 7.3. 2018 Prof. D. D. Sarma photocatalyc applicaons 27. 2. 2018 Dr. Himanshu Sharma The potenal of CRISPR technology 23. 2. 2018 Prof . Sanjay Kumar Bhadada Osteoporosis and its effect on health Influence of supporng amorphous carbon film thickness on 1. 12. 2017 Dr. Somnath Bhaacharyya measured strain variaon within a nanoparcle

23 11 2017 Dr. Swarup Panda Atomic -Scale Magnesm on a Complex Surface

26 10 2017 Dr. Ambarish Ghosh Novel applicaons of Helical Nanomaterials

27 10 2017 Dr. Manu Jaiswal Substrate Regulated Morphology of Graphene Membranes

2-D Nano MoS2 and its Lithium, Sodium Storage Mechanism 16 10 2017 Dr Sagar Mitra Study-A Experimental and Theorecal Approach

Selecvity engineering in the Synthesis of Chemicals and 14 10 2017 Prof. G. D. Yadav Materials from Biomass and Carbon Dioxide Engineering the TiO2 -Graphene nanocomposi tes towards 13 10 2017 Prof. Somnath C Roy beer light harvesng Towards innovave nano material explorer/drone prototyped 13 10 2017 Prof. Hideomi Koinuma for Japan-India collaborave research and global business

Design and development of materials for energy storage and 04 10 2017 Dr. Mani Karthik conversion 27 9 2017 Dr. Tripta Bhaa Biophysics of the lipid -protein membrane Our efforts towards manufacturing metal a nd metal oxide 22 9 2017 Dr. B. L. V. Prasad nanomaterials by connuous flow methods and the story of “self-expandable non-vascular stents Opcal tweezers for determinaon of rotaonal moon in the 18 9 2017 Prof. Basudev Roy mesoscopic domain

14 9 2017 Prof. Jai P Mial Breaking Bonds to Orde r –A Dream Sll Alive? Tailoring properes of low dimensional systems: 14 9 2017 Dr. Chiranjib Majum der A perspecve.

13 9 2017 Dr. Amit Sharma The chase for fut ure smart cancer theranoscs Sharing Drug Discovery experience in the area o f Oncology 05 9 2017 Dr Ruchi Tandon and Respiratory Biology: Current Challenges & Future Opportunies

Nanoparcles from Polypepdes and Pepde Nucleic Acids: 04 7 2017 Prof Krishna N Ganesh Structures and shape s Assembling Atomic Clusters in 3D for New Physical and 16 6 2017 Prof. Arun Chaopadhyay Chemical Properes 16 6 2017 Prof. Amitava Patra Luminescent Nanomaterials: New Generaon Light Sources

24 –30 March Lecture series: Introducon to NMR in Solids and Mossbauer Prof. Laxmi Chand Gupta 2017 Effect

10 3 2017 Prof. Seiichiro NakabayashiI Nano Bubbles at Normal Hydrogen Electrode

70 Institute of Nano Science And Technology b) Organizing of Special Lecture: I. 3rd INST-Langmuir Lecture: INST organizes two lectures named aer Professor Irving Langmuir and Professor Richard Feynman, christened INST-Langmuir and INST-Feynman Lectures respecvely. The last two INST-Langmuir lectures were delivered by Prof. CNR Rao and Prof. Steve Granick. The 3rd INST-Langmuir Lecture was delivered by Prof. Ayusman Sen, Pennsylvania State University on 22.12.2017. The s p e a ke r P ro f. Ay u s m a n S e n , Disnguished Professor of Chemistry, The Pennsylvania State University is a Fellow of the American Associaon for the Advancement of Science. He is acvely working on self-powered nanomotors and micropumps. He is Prof Sen during the lecture the author of approximately 350 scienfic publicaons and holds 24 patents. Prof Sen delivered the lecture on the tle “Fantasc Voyage: Designing Self-Powered Nanobots”

II. 2nd INST-Feynman Lecture: INST organizes two lectures named aer Professor Irving Langmuir and Professor Richard Feynman, christened INST-Langmuir a n d I N ST- Fey n m a n L e c t u re s respecvely. The first INST-Feynman lecture was delivered by Prof. James Heath of California Instute of Technology. The second lecture under this series was delivered on 28th of December in IISER Mohali by Prof. Pulickel M. Ajayan, Rice University on the tle“Materials Science and Nanotechnology”

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12) Foreign visit of INST Faculty: I) Academic visit of Dr. Kamalakannan Kailasam, Scienst E and Dr. Kiran Shankar Hazra, Scienst - C to Saitama University, Japan during July 29 – August 6, 2017 Dr. Kamalakannan Kailasam, Scienst E and Dr. Kiran Shankar Hazra, Scienst-C were invited by Dr. Seiichiro Nakabayashi, Vice Rector of the University, Professor of Physical University, Saitama University, Saitama, Japan under the Lab-to-Lab program to visit Saitama University during 30th July to 06th August, 2017. They have visited various labs related to their research areas and interacted with the principal invesgators and students. Being a young faculty, it was a good exposure for them to see how research labs are set up and organized in a very limited space and with opmized resources. It was very encouraging for them to see how sciensts are developing and modulang their own measurement set up instead of purchasing from vendors. It was indeed a good learning for them and can directly benefit research group. The academic visit to Saitama University, Japan provided a strong interacon and collaborave possibilies as many of the Professors have complementary research experse to their group's research acvies. They interacted extensively with several sciensts and tried to explore some possibilies of bi-lateral collaboraons. Dr. Kamalakannan Kailasam, Scienst E and Dr. Kiran Shankar Hazra also gave a research talk at Saitama University highlighng overall research acvity of INST and recent research acvity in research group. The talks were very interacve and opened up new ideas and possible collaboraon. It was really rejoicing to find humbleness and helping nature of the Japanese sciensts and students. They also visited labs of several faculty members and explained their work and the instrumentaon they are using. The tailor-made assembled systems were present in each laboratory (Sensing, AFM and Laser systems) and it was indeed a great learning experience. The students explained their research work and enquired about possible exchange programs to perform their research in India. Overall, the visit was a very successful one with possibility of overseeing future research collaboraons that will lead to academic understanding and results in high impact publicaons and beyond.

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II)Visit of Dr. Vivek Bagchi to Rome, Italy on September 04-06, 2017 Dr. Vivek Bagchi, Scienst – C INST ha aended a conference entled "World Chemistry Conference" on September 04-06, 2017 at Rome, Italy and delivered a talk during the session tled “Advanced Nanostructured Materials for HER Applicaons”. This meeng mostly focused on finding sustainable soluons to issues related to energy, water and healthcare etc. through possible collaboraons and effecve internaonal exchange programs. An interacve poster session was organized in the meeng, which allowed him to interact with the experts on the panel. Around seventy scienfic lectures were delivered over the tenure inculcang key advances in nanoscience and technology among the young brains. It was a wonderful experience to interact with so many eminent sciensts which helped broadening his views towards the area of research.

III) Visit of Prof Ashok K Ganguli, Founding Director, INST and Prof H. N Ghosh, Scienst - G, INST to China during28-30 October, 2017: Prof Ashok K Ganguli, Founding Director, INST and Prof H N Ghosh, Scienst - G were invited by Prof. Yanlin Song, Chinese Academy of Sciences (ICCAS), Beijing, P. R. China to parcipate and deliver a talk at the 8th MRS Trilateral Conference on Advances in Nanomaterials: Energy, Water & Healthcare held at the University of Chinese Academy of Sciences, Beijing, from 28th to 30th October, 2017. The said conference was organized jointly by the Chinese Materials Research Society and Instute of Chemistry, Chinese Academy of Sciences (ICCAS). The conference brought together experts from the Chinese Materials Research Society, the Materials Research Society of Singapore, and the Materials Research Society of India. IV) Visit of Prof H. N Ghosh, Scienst - G, INST to Germany during November 14-17, 2017 Prof H N Ghosh, Scienst- G was invited by Prof. Dr. Andreas Dreuw, Interdisziplinäres Zentrum für Wissenschaliches Rechnen Theorecal and Computaonal Chemistry, UNIVERSITAT HEIDELBERG to aend an Indo-German Meeng held at the Interdisciplinary Center for Scienfic Compung at Heidelberg University from 14-17th of November, 2017 for "Elementary Reacons in Funconal Materials: From Biophysics to Technological Applicaons”. About thirty parcipants from India and Germany have aended this iniave for fostering new and exisng collaboraons among the scienst. V) Visit of Dr. Rahul K Verma to U.K. (Scotland) during December 6-8, 2017 : Dr. Rahul Kumar Verma, Sci - D had parcipated in Drug Delivery to Lungs (DDL)-2017 held during 6 - 8 December 2017 at Edinburg, Scotland, UK. The Drug Delivery to the Lungs conference (DDL) is Europe's premier conference and industry exhibion, which is dedicated to pulmonary and nasal drug delivery. The focus is on providing a forum to present through podium and poster presentaons recent developments in the field of inhalaon therapy.

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Each year the DDL commiee invites a long serving respiratory health professionals to deliver the commemorave DDL lectures as a way of recognizing their significant scienfic accomplishments achieved in respiratory health. The lecture programme also features a slot dedicated to junior researchers.The three-day conference consists of a programme of lectures covering five session themes.

The DDL conference provides an annual forum for sciensts, academics, clinicians, regulatory and industry specialists involved in developing medicines for inhalaon. DDL-2017 had five themed sessions each with a combinaon of invited and submied lectures given by experts in the field of inhalaon and students working to advance respiratory science. The topics include inhalaon research (pharmaceucs/clinical/pharmacy pracce etc.), tradional therapies, regulatory issues, future developments of inhalaon therapies. Around 500 Sciensts, researchers, academicians and students from different parts of world has parcipated in this event. Dr. Verma has parcipated as a speaker and delivered a talk on the tle: “Hybrid Nano-in-Micro Systems for Lung Delivery of Host Defence Pepdes (HDP) using as Adjunct Therapeucs for Pulmonary TB” in the meeng. Since, Dr. Verma is also working in the area of Inhalable Nanomaterial for therapeuc applicaons, parcipaon in this conference has enhanced his knowledge and also give him an opportunity to interact with other sciensts in this field.

VI) Visit of Prof H N Ghosh, INST to Thimphu, Bhutan during 12-13 March 2018: Prof H N Ghosh, Director, INST has been invited by Dr. H. S. S. Ramakrishna Mae and Prof. G. U. Kulkarni, Director and (Conveners), CeNS, Bangalore to parcipate and deliver an invited talk in the conference entled “Conference on Physics and Chemistry of Materials” during 12-13 March, 2018 at Thimphu, Bhutan. The said conference has been organized by Centre for Nano and So Maer Sciences, Bengaluru, Karnataka. During the 2 day conference, Prof Ghosh has delivered the lecture on “Ultrafast Exciton-Plasmon Interacon in Semiconductor-Metal and Semiconductor-Janus Hetrostrcutres”. Overall, the visit is very successful one with overseeing future research collaboraons that will lead to academic understanding and results in high impact publicaons and beyond.

VII) Visit of Dr. Ashish Pal to Thimphu, Bhutan during 12-13 March 2018: Dr. Asish Pal, Sc-E, INST was invited to parcipate and deliver lecture in the conference “Physics and Chemistry of Materials”, which was aended by high profile Indian sciensts in the field of material science. The conference was held during 12-13th March, 2018 at hotel Osel in the serene Thimphu valley, where the sciensts came together to discuss the recent advancement in

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13) Conferences/Workshop Organised by INST

1) New Dimensions of Chemistry at the Aahana Resort, Jim Corbe Naonal Park, Uarakhand, during May 03-05, 2017 INST, Mohali in associaon with InternaonalCentre for Materials Science (ICMS), JNCASR, Indian Instute of Technology (IIT), Bombay and Indian Instute of Chemical Technology (IICT), Hyderabad, has conducted a focused conference on “New Dimensions of Chemistry” at the Aahana Resort, Jim Corbe Naonal Park, Uarakhand, during May 03-05, 2017. This focused conference involved 20 eminent Indian sciensts from various research instutes and universies. The parcipants for this conference are recognized globally for their contribuon in the field of Chemical Science and have been working on cung edge science. 25 young sciensts who have started their career in IIT's, IISER's and several universies also took part in the deliberaons. In addion to the technical lectures, there was a special Brain storming session on “Future of Chemistry” chaired by Prof. C. N. R. Rao.

2) Recent Advances in Nano Structured Powders, Films and Devices (NFD 2017) Conference Report during 15-16 September, 2017 Instute of Nano Science and Technology (INST), Mohali has organized a meeng on “Recent Advances in Nano Structured Powders, Films and Devices” during 15th and 16th September, 2017. This meeng was held at the quiet hill top of Kasauli, HP and has offered an excellent plaorm for eminent sciensts, academicians & young researchers to share their latest discoveries and exchange knowledge. This conference has aimed to focus on very specific fields of Nano science and Nanotechnology with emphasis on various applicaons of nano structured powder and films. Almost 42 parcipants parcipated including 18 invited speakers from all parts of the country. In an elaborate poster session research students presented their recent work in this field and interacted with the eminent sciensts.

Prof Mittal during the lecture

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3) 3rd Har Gobind Khorana Lecture: INST in associaon with Punjab State Council for Science and Technology (PSCST) instuted a lecture in the field of Bio-Science and considerd to name the same aer the eminent Punjabi Nobel Laureate and Bio-Scienst, Prof. Har Gobind Khorana. In this direcon, the first lecture under this series was delivered by Sir Venkatraman Ramakrishnan, Nobel Laureate, on 05th January 2016 at Panjab University, Chandigarh, where he delivered a lecture on “On Nobody's Word: Evidence and Modern Sciences”.The second lecture under this series was delivered by Padma Shri, Prof. Gurdev S. Khush, FRS, the world renowned plant breeder and genecist on 27th March 2017 at IISER-Mohali.

This year, INST in collaboraon with Punjab State Council of Science and Technology,Naonal Agri- Food Biotechnology Instute (NABI), Mohali and Indian Instute of Science Educaon and Research, Mohali have organized the 3rd Har Gobind Khorana Lecture on Wednesday, 6th December, 2017 at NABI, Mohali.

Dr. Uam L RajBhandary, Lester Wolfe Professor of Molecular Biology, Massachuses Instute of Technology has kindly delivered the lecture held at Naonal Agri-Food Biotechnology Instute, Knowledge City, Sector 81, SAS Nagar, Punjab. This unique plaorm has provided young researchers to interact scienfically with famous and eminent sciensts from all across the globe, most of whom were associated with Prof. Har Gobind Khorana and to listen to their first hand experiences of interacon with Prof. Khorana.

This symposium provided a good plaorm to all working in different areas of Genes, Genomes and Membrane Biology for networking and meet with some of the eminent peers in the field. The extensive and impressive list of speakers, will definitely lead to intense discussions and ignite new ideas in the young minds.

4) A special conference for ST researchers on Recent Advances in Nano Science and Technology (RANST)

Instute of Nano Science and Technology (INST), Mohali has organized the said Conference at INST for the purpose of raising the awareness of researchers belonging to the ST-category during 19th to 21st December 2017. Parcipaonswere mainly in the form of oral and poster presentaons and Plenary and Invited talks. Although the majority of the parcipants (23) were from the ST-category; however, a few competent non-ST Faculty members (12) were also joined as Plenary/Keynote and Invited Speakers.

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Parcipants are from different universies, instuons such as Nagaland University, Central University of Rajasthan, Osmania University, IGNTU, NIT Tiruchirappalli, BHU, Naonal Instute of Nutrion, PGIMER Chandigarh, NEHU, CSIR-IMMT, IISER Trivandrum, JNTU etc. all over India.

The parcipants benefied from this event by learning current research undergoing in the area of Nano science and technology. It also provided plaorm for effecve interacons among different faculty members, students and to iniate possible collaboraons on joint projects of mutual interest.

Prof. B R. Jagirdar, IISc, Bangalore during the lecture Participants during the conference

Prof. A.K. Dinda, AIIMS during the lecture Prof. Ganguli felicitating Prof Kulkarni

5) Special workshop for ST researchers on Advanced Techniques in Nano Science and Technology (ATNST):

Instute of Nano Science and Technology (INST), Mohali has also organized the said workshop at INST for the purpose of raising the awareness of M.Sc and Ph.D. students belonging to the ST-category in during 13th to 16th December 2017.

Parcipants are from different universies, instuons such as Nagaland University, Manipur University, Mizoram University, Osmania University, CMR Technical Campus, IGNTU, IISER Thiruvananthapuram, Cochin University of Science and Technology, Central University of Rajasthan, University of Rajasthan, IIT-BHU, Deen Dayal Upadhyaya College, University of Delhi, CSIR-Instute of Minerals and Materials Technology, Central University of Jharkhand, Guru Ghasidas Vishwavidyalaya, CK Thakur College all over India. Parcipants includes Faculty members, Ph.D. students and M.Tech students working in the field of Nano Science and Nanotechnology.

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Prof. Arun Chaopadhyay, IIT Guwaha, delivered a plenary lecture on Developing Mulfunconal nanoparcles. Followed by expert lectures covering various advanced techniques in Nanoscience and Technology by Prof. P V Bharatam from NIPER Mohali, Prof. Chandrabhas Narayana from JNCASR, Bangalore, Dr. Ashish from IMTECH, Chandigarh, Dr. Pramit K Chowdhury from IITD, Delhi, Dr. Ramendra Sundar Dey from INST, Mohali, Prof. B. R. Mehta from IITD, Delhi, Dr. Pravin P Ingole from IITD, Delhi and Prof. M. Ghanashyam Krishna from UoH, Hyderabad. A Special Lecture was delivered by Prof. Ashok K Ganguli, Director, INST on Introducon to Nano Science and Technology.

Lectures were followed by praccal demonstraon of various advanced instruments used in Nano Science and Technology like TEM, SEM, AFM, UV-Vis Spectroscopy, Photoluminescence Spectroscopy, FTIR, Raman Spectroscopy Electroanalycal Technique, Cyclic Voltametry, Potenometry and Amperometry.

Overall it provided an ample scope and opportunies for effecve interacons that enabled the parcipants to pursue research using advanced scienfic techniques. The parcipants were also benefited immensely from the event parcularly from the hands-on experience.

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6) Nano Mission School on NS&NT- Biological Sciences Workshop: Instute of Nano Science & Technology (INST), under the support of Nano Mission, Department of Science and Technology (DST) organized a special workshop on Nano Science & Nano Technology- Biological Sciences from 6-11th November at its premises at sector 64, Mohali. The workshop was coordinated by Prof Deepa Ghosh, Scienst F, INST and Dr. Jiban Jyo Panda, Scienst C, INST. The move of the workshop was to familiarize early career researchers across the country with emerging areas in nanoscience and ulize its potenal to address various challenges in agriculture, environment and healthcare. The parcipants include students (MSc/PhD) as well as faculty/sciensts working in the area of Biological Sciences and interested in the area of nanoscience.

A number of areas including Nano biotechnology in pharma and agriculture, cancer biology and nano therapy were discussed by the sciensts and experts from various State of the art Instutes of the country like NABI, NIPER Mohali, DIHAR, INST. During the workshop, special interacve and demonstraon sessions were arranged for the benefit of the parcipants. Besides, hands-on training on the use of high-end instruments like electron microscope, atomic force microscope, dynamic light scaering instrument, fluorescence microscope, circular dichroism, bio layer interferometer etc. was provided for understanding the phenomena at nanoscale. Prof. T. R Sharma, Director-NABI, Mohali was the chief guest to inaugurate the event. Hailing the iniave by INST, he said “such workshops provide excellent opportunies for the students from colleges and universies to decide their future career path.” Different days of the school were dedicated to cover topics related to various aspects of Nano Science and Technology. The first day focused on understanding the phenomena at nanoscale and to introduce t h e p a r c i p a n t s t o t h e fundamental principles of N a n o te c h n o l o g y a n d i t s biomedical applicaons in the field of ssue engineering, sensing etc. The second day showcased the progress made by nanotechnologists in the field of cancer therapy. The third and fourth day were dedicated to applicaons of Nanobio in Pharma and Nanotechnology in Agriculture. The fih day of the workshop shed light on one the most important aspects of nanotechnology, i.e. nanotoxicology.

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The last day of the workshop ended on a lighter note with poster presentaons and interacon of the parcipants with faculty members and experts at INST. Overall, it was a great learning experience for all the parcipants which provided an opportunity to understand and experience research acvies in the excing field of nanotechnology and how it can be used to tackle various problems faced by mankind.

7) 3rd CRIKC Nano Science day: The Instute of Nano Science and Technology, Mohali in associaons with Central Scienfic Instruments Organizaon (a constuent laboratories of the Council of Scienfic & Industrial Research – CSIR) has organized 3rd CRIKC Nanoscience Day on 29th August, 2017 at CSIR-CSIO, Prof Rao alongwith Prof Grover, Chandigarh. This meeng is a part of the CRIKC Nanoscience Prof Ganguli, Dr. R. Sinha Group. Prof. V. Ramgopal Rao, Director- IIT Delhi, has delivered the '3rd CRIKC-INST Nano science Lecture'. Apart from that there were presentaons by sciensts from different CRIKC instuons to showcase the research highlights of their group and their instuons. There were also presentaons from Industrial partners of CSIR-CSIO, who are working well in the area of nanomaterials. A poster session has also planned for the students from all CRIKC instuons. A parallel session was also held for demonstraon of new technology/product developed in the department/instuon under CRIKC domain. This meeng has provided the plaorm for effecve interacons to iniate discussions, joint projects and sharing of facilies for the benefit of researchers in the tricity area and nearby places. 8) CeNS-INST Joint Symposium-2017 : Instute of Nano Science and Technology Visit of delegations to the pavilion (INST), Mohali has organized a joint symposium partnering with Centre for Nano and So Maer Sciences (CeNS), Bangalore during 16-17 November, 2017. This is the first me both these instutes have come together to conduct this event to share each other's work.

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The symposium hosted 17 scienst with 8 from the CeNS and 9 from INST covering research areas in chemistry, physics and biology. Lectures were followed by poster presentaon from 24 PhD scholars, with 10 from INST and 14 from CeNS. To encourage the students interacon, special invites from Jawaharlal Nehru Centre for Advanced Scienfic Research (JNCSR) were also present. At the end of the symposium in the concluding secession poster awards were presented. From INST, Ms. Swa Tanwars poster entled “DNA origami directed self-assembled hybrid nanoantennas for single molecule spectroscopy applicaons”, Mr. Anirban Kundu, and Mr. Atul Dev backed the poster prize.

Overall, it was fruiul me with scienfic interacon to exchange knowledge and experse. Further, it also allowed the young talented PhD scholars from INST to interact with their counterparts from CeNS.On concluding talk Bharat Ratna Prof. C N R Rao announced an award for outstanding research in Nano Science and Technology, which will be given every alternate year.

14) Parcipaon of INST in various events: I. India Internaonal Science Fesval (IISF) – 2017 A team consisng of Faculty members, postdoctoral researchers and PhD students and project students parcipated in 3rd India Internaonal Science Fesval 2017, held during 13-16th October, 2017 at IIT Madras, Anna University, CSIR-CLRI and Madras University, Chennai, Tamil Nadu. Students and Faculty members and the students parcipated in the Mega Science, Technology & Industry Expo and exhibited different technologies developed at INST. Faculty membe rs also parcipated in the Sensizing Youth to Flagship Programs of Government (SYPOG) and presented poster work represenng their group's research and developmental acvies carried out at INST. Dr Jiban Jyo Panda's groups work entled, ''Pepde based neuro nano therapeucs for effecve drug delivery and ssue engineering" has been selected as one of the TOP POSTERS in the Swasth Bharat Category, in SENSITIZING YOUTH TO FLAGSHIP PROGRAMS OF GOVERNMENT (SYPOG)-IISF 2017. Besides this, women sciensts from INST also parcipated and shared their views in the Women Sciensts & Entrepreneur's Conclave.

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II. Vision Jammu & Kashmir 2018 from 29th to 31st January 2018

The Mega Exhibion“Vision Jammu & Kashmir 2018: A technological expo”was organized at Nand Palace, Udhampur, Jammu & Kashmir in order to display of latest products and technologies and discuss new ventures for Large, medium and small companies of the region.The expo also highlight various projects and technologies for the up gradaon in the Rural sector, Health, Science and Technology, Innovaons Rural Technologies, Hill area Development, Research and Development, and Women Empowerment, technological advancements and opportunies, various schemes and programmes being offered by State and Central Government departments for the beerment of the society. The Expo highlighted the creaon of growth in the host State in order to (i) Develop Networking(ii) Promoon of Innovaon (iii) Generate Awareness (iv)Technological Advancements and Opportunies.INST Pavilion This expo was organized by SANSA Foundaon Private limited. This mega exhibion was

inaugurated by Honourable Chief guest Minister of State (Independent Charge) (Ministry of Development of North Eastern Region, Prime Minister Office, Personnel, Public Grievances and Pensions, Department of Atomic Energy and Department of Space) Dr. Jitendra Singh on 29th January 2018. The main exhibitor of expo were Indian Space Research Organisaon (ISRO),Steel Authority of India Ltd, Tea Board, India, Naonal Skill Development CorporaonIndia (NSDC), Skill India, Council of Scienfic & Industrial Research (CSIR), India, Indian Council of Medical Research (ICMR),Central Silk Board (CSB), North Eastern Handicras and Handlooms Development Corporaon Ltd, Naonal Research Development Corporaon (NRDC), Northeast Regional Compung Program and Instute of Nano Science and Technology (INST). On the behalf of INST, Mohali, Dr Kaushik Ghosh and Dr Vivek Bagchi with PhD scholars showcased various technologies, which are indigenously developed at INST, Mohali. Dr Kaushik with his student Mr Surender Gaurh had demonstrated the low cost portable/flexible devices related to energy

83 Institute of Nano Science And Technology storage and renewable energy conversion. Mr. Krishna Yadav and Mr. Sujit Guchhait, students of Dr. Menaka Jha, has demonstrated the design and working of indigenously developednano- adsorbent based prototype for filter for removal of toxic impurity from waste water. They have demonstrated how the synthesized nano-adsorbent can be used for the purificaon and recycling of industrial as well as domesc wastewater. Mr. Pradipta Samanta, student of Dr Priyanka Shaberwal demonstrated Aptasensor based bio-sensors for detecon of myocardial infarcon. More than 5000 people visited the expo including local populaon of palampur and students of nearby schools and colleges.

III. Desnaon Himachal Pradesh-2017 from 12th -14th September, 2017 The Mega Exhibion“Desnaon Himachal Pradesh - 2017: A technological expo”was .organized at Palampur in order to display of latest products and technologies and discuss new ventures for Large, medium and small companies of the region.The expo also highlight various projects and technologies for the up gradaon in the Rural sector, Health, Science and Technology, Innovaons Rural Technologies, Hill area Development, Research and Development, and Women Empowerment, technological advancements and opportunies, various schemes and programmes being offered by state and central Government departments for the beerment of the society. The Expo highlighted the creaon of growth in the host State in order to (i) Develop Networking, (ii) Promoon of Innovaon (iii) Generate Awareness (iv)Technological Advancements and INST's pavilion

Opportunies.This mega exhibion was inaugurated by Honorable Chief Guest Shri Shanta Kumar, Member of Parliament on 12 September 2017. The main exhibitor of expo were Indian Space Research Organizaon (ISRO),Steel Authority of India Ltd, SAIL, Tea Board, India, Naonal Skill Development Corporaon India (NSDC), Skill India, Council of Scienfic & Industrial Research (CSIR), Indian Council of Medical Research (ICMR), Central SilkBoard (CSB), North Eastern Handicras and Handlooms Development Corporaon Ltd, Naonal Research Development Corporaon (NRDC), Northeast Regional Compung Program and Instute of Nano Science and Technology (INST).

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On the behalf of INST, Mohali, Dr Menaka Jha and Dr Rahul K.Verma with Ph.D scholars showcased various technologies, which are indigenously developed at INST, Mohali. Dr Menaka with her students, Mr Krishna Yadav, Mr Ankush and Ms.Sunaina demonstrated the design and working of indigenously developednano-adsorbent based prototype for filter for removal of toxic impurity from waste water. They demonstrated how synthesized nano-adsorbent can be used for the purificaon and recycling of industrial as well as domesc wastewater. Dr Rahul K Verma and his student Mr Ankur Sharma exhibited prototype of inhalable nano-in micro assemblies for Tuberculosis therapy and metered dose nano-spray gel for treatment of cold injury. Ms Manju Sharma, a student of Dr Priyanka demonstrated Aptasensor based bio-sensors for detecon of myocardial infarcon.

More than 6000 people visited the expo including local populaon of Palampur and students of nearby schools and colleges.

IV) Special exhibion in CSIR head quarter, New Delhi: INST student Ms. Sunaina presented technologies developed at INST related to low-cost water purificaon system for domesc & industrial waste treatment uses nano absorbents during Swacha hi Sewa campaign during September 27, 2017 at Special exhibion in CSIR head quarter, New Delhi. INST, Mohali also showcased a technology for recovering Nanostructured materials from used baeries waste & industrial waste. Hon'ble Minister of Science and Technology and Earth Science Dr. Harsh Vardhan during the exhibion

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15) Outreach @ INST I) ST Outreach Iniaves The ST-Outreach program has also embarked upon an excing project in which various young people from schools and colleges across the country are idenfied and aend workshops in our Instute which gives exposure to the vast possibilies in modern science as well as opens up the opportunity for interacon with sciensts and technologists. This year (2017-18) outreach report have been covered almost PAN-India including states like Tamil Nadu to Jammu & Kashmir and Madhya Pradesh to Assam covering length and breadth of whole India. Of the 18500 students covered under the outreach lectures about 7307 students belonging to ST community were covered during the fiscal year of 2017 to 2018.Sciensts have visited these remote schools/colleges to their libraries and science laboratories and donated consumables like books, glassware and chemicals etc., which they are in need of by consultaon with the school authories.

Himachal Pradesh

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II) INST Women Outreach program for Inmates : Under the sphere headed leadership of Prof. Ashok K. Ganguli, Director INST, the program was iniated for the women of our society. Dr. Priyanka (coordinator women outreach) along with and other team members: Dr. Sangita, Dr. Sharmistha, Dr. Deepika and Dr. Neha are working together to facilitate in organizing lectures and workshops, especially in rural areas with an idea to touch each aspect of women's life such as hygiene, basic first aid, child abuse, disaster management, sexual harassment and personality development etc. The program aims to dissipate knowledge and awareness among women from different age groups and family backgrounds, to enable them in idenfying realisc steps they want to take to make a beer world for themselves and their families alongwith their work environment. Our team organised women outreach program at Model Jail, Chandigarh on 10th July, 2017. The program started with the intoductory talk by S h . P K D a a , Consultant INST followed by talks delivered by our team of sciensts onvarioustopics viz.connecng with Nature, Women Role Models, Importance of Literacy, Importance of Posive Thinking and Women Hygiene. An aempt was made to sensize the women inmates on these issues.

87 Institute of Nano Science And Technology them for a new beginning in their lives. Outreach flyers were distributed which were printed in three languages, i.e. Hindi, English and Punjabi. With an idea of making it simple and understandable, even by illiterate people, we put more pictures, schemac and illustraons. Our Ph.D fellows and students fully contributed in designing and translang the flyer in regional languages. Women hygiene kits were distributed during the program to help women in adopng good hygiene methods. The audience showed their interest of organizing such events in the future pertaining to science and technology with a focus on nanotechnology in our life. III) INST outreach day: Instute of Nano Science & Technology, Mohali organized the 3rd INST annual outreach day in a bid to promote science and technology among the school children. The event was held at IISER, Mohali auditorium on 11th August, 2017. The program was aended by more than 400 kids across tricity and neighbouring area. Shan Swaroop Bhatnagar award winner, Prof. Uday Maitra from Indian Instute of Science, Bengaluru gave an interesng lecture with demonstraon of fun chemistry experiments to increase their interest in science. Some of the experiment were colourful magic ink, creang fluorescent colour using laser torch. While addressing the audience, he said “Science if taught in an interacve manner with demonstraon of fun experiments, can generate interest and it would encourage students to ask queson, a pre-requisite to inculcate scienfic temperament”. Earlier in the day, Prof. Arun Grover, VC, Panjab University inaugurated the event and lauded the iniave of INST in popularizing science and technology among general masses. He cited the efforts of Prof. Yash Pal, who passed away recently, in this direcon and suggested the instutes in knowledge city, Mohali to come up with Yash Pal Centre for Outreach. Dr. Jander Kaur Arora, Execuve Director, PSCST also shared her view with the children and gave a social message to encourage the girl students. During the event, 20 school students and teachers across India, Punjab, Uarakhand, Assam, West Bengal, Andhra Pradesh and Kerala, were awarded INST-fellowship to support their higher studies. These talented students and teachers were selected during their interacon with INST-outreach team during the past one year. Pooja, a student from GGSSS, Kot babadeep Singh and daughter of a daily wage worker, who came 2nd in 12th board exam in enre Amritsar district, received INST fellowship. While thanking INST she narrated her story “I was on the verge of quing my study during Class 11 due to financial obligaon. Aer the visit of INST outreach team at my school, I felt movated and took it as a challenge to connue my study with the support of INST-Kalpana Chawla fellowship”.

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Prof. Arun Grover, VC, Panjab University, Dr. Jander Kaur Arora, Execuve Director, PSCST, Prof. Uday Maitra from Indian Instute of Science, Bengaluru, Prof A. K Ganguli, Director, INST alongwith awardees of Outreach Award. 16) Other Acvies @INST : I) Celebraon of 5th foundaon day: Instute Nano Science & Technology (INST) celebrated its 5th Foundaon day at NABI auditorium, Knowledge city, Mohali on 7th March, 2018. Prof. Dipankar Das Sarma from Indian Instute of Science, Bangalore was the Chief Guest and he delivered the foundaon day lecture entled “Organic-inorganic hybrid perovskite materials for photovoltaic applicaons”. The programme was graced by Prof. Tilak Raj Sharma, Director- NABI as guest of honor and other dignitaries and was aended by more than 300 audiences. In his introductory remarks, Prof. H. N. Ghosh, Director-INST (Officiang) showcased the young instute's achievement in last 5 years. Finally, INST scienst and students showcased their talents through an enthralling cultural program.

INST's students and staff during Giddha

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II) Bhoomi Poojan : INST Campus Ground breaking ceremony (Bhoomi Poojan) of INST's state-of-the-art Campus at Sector- 81, Knowledge City, Mohali (adjacent to IISER Campus) was performed on 25th May, 2017. Bharat Ratna, Prof CNR Rao, Chairperson, Board of Governors (BoG) of INST was the Chief Guest of this funcon. This event was aended by all INSTian and the senior funconaries of neighbouring instuons including Heads of CRIKC instuons. To make the event a memorable one presentaon/models of Campus panoramic view, Animal House & STP,Main Building Front View, Administrave Block internal view, Seminar Complex (Internal View) Seminar Hall, Library, Laboratory Internal View, Guest House etc were displayed.

Prof Rao along with other functionaries during the event

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III) Observaon of “Swachhta Hi Seva” campaign:

On 2nd October 2014, Swachh Bharat Mission was launched throughout the country as a naonal movement. It was a befing tribute to the Father of the Naon who was concerned about sanitaon issues. The campaign aims to achieve the vision of a 'Clean India' by 2nd October 2019. The naon-wide sanitaon campaign from 15th September to 2nd October 2017 has been named as “Swachhta Hi Seva” by the honourable Prime Minister.

The Swachh Bharat Abhiyan is the most significant cleanliness campaign by the Government of India. Rising to the need of the hour, under the dynamic leadership of the Director, Prof. Ashok K. Ganguli; INST-Mohali has successfully organised the various acvies, which include poster and slogan wring compeon, a small play to sensize the students and staff about the importance of cleanliness, tree plantaon, cleanliness drive in the adopted school and E- cleaning.

Pledge Taking:The whole campaign started with the taking of a pledge on 15th September. The students, Sciensts and staff pledged to dedicate two hours weekly and hundred hours a month towards the programme for the next five years. Tree Plantaon: To save the earth and to prevent environmental degradaon, tree plantaon programme has been organised as a part of Swachhta Abhiyan. It is the crying need of the hour to promote afforestaon and plant more and more trees. Our honourable director, Prof. A.K. Ganguli along with the staff planted samplings in the backyard of the Instute. This Tree Plantaon Program has mobilized students into a community of passionate tree planters and lovers who will work towards prevenng loss of green cover and keeping the environment green and clean.

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Lab Cleaning:Students of INST have taken an integral part in Swatchh Bharat Abhiyan by cleaning their labs, which can be well perceived from the pictures. Cleaning of lab includes cleaning instruments, desktops PCs, proper disposal of waste chemicals and maintenance of their records.

Cleaning of Premises:An instute's environment is healthier when they are kept clean and is maintained well. INST staff efficiently maintains the cleanliness of the Instute premises. In the spirit of the campaign, the staff themselves cleaned the surroundings.

Play/Drama on cleanliness: A play was staged by Ph.D. students to sensize the students and staff about the Swachhta Abhiyan in the Instute and also in the adjoining adopted school as well. It inspired the audience not only to clean their houses, but also to keep their surroundings clean. This was a great effort by the doctoral students.

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Slogan and Poster Presentaon: Swachh Bharat Mission “POSTER” and “SLOGAN WRITING COMPETITION” was organised in our Instute in order to communicate an essenal message to educate students and staff about cleanliness. Students as well as Faculty and Staff acvely took an acve part in the compeon. Cleanliness Drive in the Adopted School: The Swatch Bharat Abhiyan was not limited to the instute, the adjoining school adopted by INST was also involved in this campaign by clearing the weeds on the rooop of the school, making students clean the playgrounds, etc. The INST staff also organized various awareness programs through outreach acvies in the school. Director-INST, Prof. A.K Ganguli, addressed the students and teachers of the school about the combined effort to keep their surroundings clean and healthy.

IV) INST's Technology Day Award: On the basis of the recommendaons of the Naonal Selecon Commiee, the INST Naonal Technology Day Award 2017 was conferred to Dr. Priyanka for her project on 'Novel nanostructures based biosensing for clinically important cardiac biomarkers' and the consolaon prizes were given to ; Dr. Kiran Shankar Hazra (for the projects 'Microscope-less low cost microprobe staon' and 'Focused laser based direct lithography') and Dr. Menaka Jha (for the project 'Design of nanoadsorbent for treatment of Industrial and Domesc polluted water') 5th Meeng of the Research and Academic Advisory Council of the Instute of Nano Science and Technology, Mohali held on 5th July 2017.The award for this purpose, is a research grant to be used for purchase of consumables, maintenance of equipment, hiring short-term manpower, travel related to conferences or research collaboraons, honorarium and travel for experts vising INST etc., V) Celebraon of Annual Sports Day: The Recreaon and Sports Club of INST organized two-day sports events on 16-17th February, 2018 as annual sports day of the instute. The following sports events were organized: Badminton (Singles, Doubles and Mix-Doubles), Table Tennis, Cricket, Racing and Tug of War. INST's faculty, staff and students parcipated in this events with great enthusiasm.

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17)Awards and Honors to INST:

1) Prof. C.N.R. Rao “NANO Science Award'” for the year 2017 to Prof Ashok K Ganguli :

Prof Ganguli, Director, INST has been conferred “India Nano Science Award 2017”. This award has been constuted by Department of IT, BT and S&T, Govt of Karnataka, under the guidance of Vision Group on Nanotechnology led by Bharat Ratna Prof. C.N.R. Rao. This is one of the presgious award in area of Nano science and Technology

Prof Ganguli receiving the award during 9th Bengaluru INDIA NANO 2017 on 9th December, 2017

2) Congratulaon to Dr. Abir De Sarkar on being conferred the Awards for Excellence in Nanoresearch for the year 2018 by the CNR Rao Educaon Foundaon

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Student's Recognitions: Sr. Student Recognitions 1. Mr. Anirban Kundu received the 'Raman Charpak Fellowship 2017' by CEFIPRA for six months research work at CEMES-CNRS, France. Mr. Anirban Kundu received the best poster award in joint INST-CeNS Joint Symposium for 'Experimental Evidence of Abraham Pressure on Graphene Oxide Surface' on 16th and 17th November, 2017 Hampi, Karnataka.

2. Ms. Pooja Sharma received best poster award at the Har Gobind Khorana Memorial Symposium on Genes, Genomes and Membrane Biology during 3-5th December 2017 at NABI Mohali, India. 3. Mr. Munish Shorie was chosen for the final round of NanoSparx Innovaon compeon in 9th Bengaluru Nano 2018. Mr. Munish Shorie and Ms. Harmanjit Kaur received Naonal Technology Day award 2017 for “Novel nanostructures based biosensing for clinically important cardiac biomarkers” 4. Ms. Harmanjit Kaur was chosen finalist in NanoSparx Innovaon compeon in 9th Bengaluru Nano 2018 5. Ms. Renu Rani received best poster award in Recent Advances in Nano structured powders, films and devices held on 15-16 Sep 2017, Kasauli, Himachal Pradesh 6. Ms. Deepika Rani received Royal Society of Chemistry,best poster award in CACEE 2018 organised by TIFR Mumbai from 10-12 January 2018

7. Mr. Atul Dev received best poster prize in joint INST-CeNS meeng for Protein Nano carrier based drug therapy as epigenec modulators in cancer on 16th and 17th November, 2017 8. Ms. Ankush Garg received the best poster award at the Har Gobind Khorana Memorial Symposium on Genes, Genomes and Membrane Biology during 3rd-5th December 2017 at 9. Mr. Naimat K Bari received the best poster award at the ACS on Campus event held at IISER Mohali on February 9th, 2017. 10. Ms. Taru Dubey received best poster award in Internaonal conference on Advances in Polymer Science & Technology (APA 2017) held on 23-25 Nov 2017, New Delhi&Ms. Taru Dubey received best poster award in 2nd CRIKC Nanoscience Day held on 8 Aug 2016, Mohali 11. Ms. Harsimran Kaur received best poster award in 3rd CRIKC Nanoscience day held on 29th Aug 2017, at CSIR-CSIO Chandigarh, India; &Ms. Harsimran Kaur received best poster award at the Har Gobind Khorana Memorial Symposium on Genes, Genomes and Membrane 12. Ms. Khushboo Soni Received 1st prize for poster presentaon in 3rd CRIKC Nanoscience Day, held at CSIO Chandigarh on 29 Aug 2017 13. Mr. Sk Riyajuddin received best poster award (Physics) in 3rd CRIKC Nanoscience Day held at CSIO Chandigarh on 29 Aug 2017 14. Dr. Somen Dey received best poster award in Recent Advances in Nano Structured Powders, Films and Devices, 2017 15. Shri Ashmeet Singh received presgious Weikfield Award (cerficate and cash prize) at the 9th Bangalore India Nano conference from the Donor, Mr Malhotra and from Bharat Ratna Prof CNR Rao.

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17) INST-Industry partnership

INS T- Industry Acvity 2018 INST has taken iniaves to address Industrial problems through consultancy or collaboraons through industrial projects. This iniave will nurture the students, postdocs and faculty to apply their scienfic knowledge to support industry and come up with advanced technologies (high valued products and lower cost) which would help the industry is resolving some of their challenging hurdles. Following industrial projects are under progress: a) Development of Process for imparng Adhesion Characteriscs to Nylon and Polyester

(Team Members: Dr. Sangita Roy, Dr. Asish Pal, Dr. Jayamurugan Govindasamy & Prof. Ashok K. Ganguli) Ÿ Through chemically modified monomer with reacve cross-linking sites for interfacial

Ÿ Opmizaon to improve adhesion with rubber Ÿ Adhesion tesng of the materials and opmizaon of scale up process b) Method development for measurement of thermal conducvity of Heat Transfer fluid (HTFs) (Team Members: Chandan Bera, A.K. Ganguli, Menaka Jha, Kamalakannan Kailasam) Measurement of thermal conducvity by 3 omega and transient hotwire technique of heat exchange materials for solar-thermal storage. c) Extracon of nanostructured materials from gaseous effluents of power plant Global warming is a burning issue worldwide because of toxic components in the polluted air causes several health issues. The polluted air is generally composed of smoke, dust, and greenhouse gases (flue gases). Recently, the research group at INST Mohali and Naonal Thermal Power Corporaon (NTPC) Netra has jointly developed a technology to convert power plant pollutants to valuable materials which is in high demand. The team has ulized gases effluents gas to convert industrially important material. The lab scale as well as pilot scale studies has been completed and looking forward to have industrial scale set-up at NTPC power plant.

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INST and NTPC now planning to take up this to the commercial scale. d) Applicaon of nanotechnology in making Gold Jewellery

Team Members: Dr. Menaka Jha and Prof. Ganguli INST is working with Titan for the fabricaon of next generaon jewelry. Where we are in process of development of enamel using gold nanoparcles on the surface of the jewelry thereby replacing the convenonal materials (Non-gold based enamels). e) Low cost thermal insulaon materials: Ÿ New nanocomposites from waste sources: abundant biomass-derived cellulose & Fly ash Ÿ 1 Kg/batch with strength of >100 MPa of most efficient and environmental-friendly insulator Ÿ Teaming-up with Ingersoll Rand for large-scale producon & calculaons for energy minimized buildings Ÿ Thermal insulaon efficiency about 30-60% (current polymers like polystyrene, have efficiency only about 3-8%)

Lower temperature method leading to stronger and transparent gel Team Members: Dr. Chandan Bera, Dr. Kamal and Dr. Sangita

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Technology developed at INST: 1. Low cost apta-sensor for cardiac marker myoglobin: INST has developed low cost aptasensor for the detecon of cardiac marker (myoglobin) in the management of heart aack. The nanostructured sensor can specifically detect even trace amount (upto picograms) of Myoglobin which is released in paents' blood on the onset of Heart aack.

2. Filtraon system based on Nanostructured Materials for recycling of Industrial and Domesc waste water: INST has made a low cost Cartridges for purificaon of industrial and domesc waste water. (Dr. Menaka Jha Group)

3. rGO/PS Based Flexible and Non Cryogenic Bolometric Sensor : INST has developed Graphene polymer composite based low cost flexible bolometer for temperature sensing, This Polymer based FLEXIBLE bolometer can be used for temperature sensing in biomedical applicaons. ( Dr. Kiran Shankar Hazra group )

4. Novel pepde epitopes for detecon of typhoidal Salmonellosis This technology is for the serological detecon of bacteria of the genus Salmonella. It uses a chemo bio sensing plaorm prepared with self-assembled monolayer (SAM) of carbon disulphide (CS2) on gold electrodes for specific detecon of Vi angen in S.Typhi. This work is done in collaboraon with Im Tech, Chandigarh with PGIMER, Chandigarh. Status: Technology Transferred, (Dr. Priyanka group)

5. An economical and reusable air purificaon device for harmful pollutant and VOC Sequestraon:

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1) Electronic pre-filter uses electric field to agglomerate the sub-micron size parcles and can be trapped in the filter. 2) Customizable filter which will not only absorb the volale organic compounds (VOC) but also are capable of removing ammonia or any other major pollutant from the air. This filter is based on nano-porous material which have very high surface area and can adsorb high concentraon of pollutant. 3) HEPA filter which can trap parculate maer above 2.5 micron. Patents: a) A nanoadsorbent for removal of lanthanide ions from water and associated methods,A.K. Ganguli, A. Barua, M. Jha, Indian patent no. 201711016720, dated May 12, 2017. b) A cellulose- metallothionein conjugate for metal binding, sharmistha sinha, naimat kalim bari, shaswat barua, ankush garg, file number: TEMP/E- 1/35136/2017-DEL c) Ferlizer delivery system. Vijayakumar, P.S.; M. Singh; A.K. Ganguli; Pulkit. Patent filed 201811001751 January 16, 2018 d) Flagellin (FliC/FljB) pepdes for the specific detecon of Salmonellosis: a new method and a device thereof, Priyanka, Patent No: T.I (01)/TIFA/2018 e) Conversion of starch into water purifier and field emier, Menaka Jha, Arabinda Barua, Nishan, Bharat, Santanu Ghosh and A. K. Ganguli. Patent applicaon under progress f) Extracon of silica using industrial waste, Menaka Jha, Manu Sharma, Krishna Kumar Yadav and A.K. Ganguli, Patent applicaon under progress

Summary: Total industrial projects: 13 Ongoing: 5 Discussion: 9 Ÿ SRF Ltd., 2 (Ongoing : 1; Under discussion:1) Ÿ Indian oil Corporaon (Ongoing : 1) Ÿ NTPC: (Ongoing 1 + 1 under process) Ÿ Ingersol Rand (ongoing) Ÿ Titan: 3 (ongoing-1) (Under discussion-2) Ÿ Tata Steel (Under discussion -1) Ÿ Farmson Pharmaceucal Gujarat Pvt. Ltd (Under discussion)-1 Ÿ Shree Simhaas Associates (Under discussion-2)

INST iniave to address societal issue The Instute of Nanoscience and Technology (INST) through its research acvies is acvely involved in addressing issues facing society under the Swasth and Swatch Bharat iniave of the Government of India. Under this iniave, it has developed two technologies (menoned below) to help the people of Punjab to address the issues of environmental polluon as a result of stubble burning and to provide a low cost technology to provide clean drinking water. INST seeks the support of the government of Punjab, to establish and test the said technologies at the pilot scale level

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A) Addressing environmental Polluon caused by stubble burning: The technology involves the Conversion of gaseous effluents into valuable nanostructured materials (Dr. Menaka Jha and Prof. Deepa Ghosh) INST has developed a technology that traps the gaseous effluents and converts them into valuable products. The aim of the present proposal is towards the implementaon of this technology that converts gaseous effluents released while burning plant waste (Hay/stubble) into nanostructured materials. Reaction where conversion of gaseous efuents into sodium

Technology Benefits to the Farmer: Ÿ Sodium carbonate is useful as detergent: Farmers can sell the Sodium carbonate to the soap making industries or can make soap themselves (support can be provided by INST for soap making) Ÿ Ash can be mixed with cement for making concrete. This would reduce the cost of construcon (Research is in progress) Ÿ This technology causes no polluon, hence has immense health and environmental benefits Ÿ The products can be ulize in rural society for improving quality of life. B) Addressing water Polluon caused by excessive metal ions in water We have developed water filtraon cartridges for removal of toxic metal ions from waste water (Dr. Menaka Jha) The consumpon of drinking water containing soluble metal ion is one of the major threat to our society and there is need Figure 2: Cartridge for to have a technology to deal water soluble metal ions To absorption of metal ion address this issue, a research group at INST Mohali led by Dr. Menaka Jha have been working in the area of absorpon of metal ion using nanoadsorbent synthesized using waste materials as a source. It has been know that in RO system, we have seen lot of water are discarded and dumbed back into our eco system. Here, we have made a low cost filter with Zero loss of water, as well as it prevents metal ions immobilizaon into our ecosystem. Our excellent adsorpon capacies of nanoadsorbent encourage us to do field trail of this work and hence here we need help of Indian Punjab Government to test the efficacy of this technology in the field condion. We need Infrastructure/Manpower support in implemenng the above technology in polluted area of Punjab (10 places).

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19) Human Resource (Scienfic & Administraon) A) Dr. Dipankar Mandal, Scienst E

Dr. Dipankar joined this instute as a Scienst – E on 01/1/2017. H i s Re s e a rc h I nte re st a re P i ezo, P y ro & Fe r ro e l e c t r i c Materials,Mechanical and Thermal Energy Har vesters (Nanogenerators),Self-powered Electronics,Bio-signal Monitoring via Non-invasive Biosensor, e-Skin Prior to joining INST, he has worked as an Assistant Professor at Jadavpur University. He is holding very strong research profile. Currently his h index is 22 and total number citaon is exceeded 1000 so far. His work are published in highly reputed journals, such as Nano Energy, ACS Applied and Interface, Langmuir, ACS Sustainable Chem. Engg, Applied Energy and Nano Scale. Joining of Dr. Mandal has strengthenedINST's research, since he has been working on energy harvesng area, in parcular mechanical and thermal energy harvesng by means of nanogenerator. Noteworthy that few of his research finding are highlighted in editorial press release (such as American Chemical Society, American Instute of Physics), electronic and print media. Besides, he has hands on experience on several types of sensor fabricaon which has wide range applicaon including remote health care monitoring. B) Dr. Indranil Sarkar, Scienst E

Dr. Indranil, joined this research instute on 30.11.2017. His research Interests are Low energy electronic materials, Spintronics, Nano- magnesm, Magnec sensors Before joining INST, he has worked in some of the best internaonal labs involved in nano-research. His joining has strengthened our energy and nano-device research iniaves. He has extensive research experience in the field of spintronics and nano-magnesm. His experiences and interests will bolster our research in the field of energy harvesng and novel electronic device/sensors.

C) Dr. Goutam De, Vising Scienst :

Dr Goutam De, Ex-Chief Scienst of CSIR-CGCRI, Kolkata has joined INST as a Vising faculty on February 09, 2018. His research interest includes: Funconal nanocomposite coangs of technological importance, Ordered mesoporous films and electrospun nanofibers, AR & self- cleanable coangs on solar cover glass, Fluorescent nanomaterials & coangs Nanomaterials for photo catalysis. He is a well-known materials scienst and an associate editor of the high impact journal “J. Mater. Chem. A”, published by the RSC. Possessing an outstanding academic and research credenals, Dr. De has published 151 research arcles on funconal nanomaterials and coangs and filed 9 patents. Joining of Dr. De at INST would strengthen the instute's current R&D program. 101 Institute of Nano Science And Technology

Others Sr. Name Designaon Founding 1) Prof. A. K. Ganguli DIRECTOR Director(offg) and 2) Prof HN Ghosh Sc-G 3) Dr. Deepa Ghosh Sc-F

4) Dr. A. De Sarkar Scienst E 5) Dr. S. Karmakar Scienst E 6) Dr. D. Patra Scienst E 7) Dr. A. Pal Scienst E 8) Dr. E. Ali Scienst E 9) Dr. K. Kailasam Scienst E 10) Dr. S. Sinha Scienst E

11) Dr. S. Chakraverty Scienst E 12) Dr. K. Ghosh Scienst D Dr. J. 13) Scienst D Govindasamy 14) Dr. R. K. Verma Scienst D 15) Dr. J. J. Panda Scienst C 16) Dr. K. S. Hazra Scienst C 17) Dr. Priyanka Scienst C 18) Dr. P.S.V. Kumar Scienst C 19) Dr. S. Roy Scienst C 20) Dr. S. Vaidya Scienst C 21) Dr. T. Sen Scienst C 22) Dr. A. Shanavas Scienst C 23) Mr. B. Prakash Scienst C 24) Dr. C. Bera Scienst C 25) Dr. M. Singh Scienst C 26) Dr. Monika Singh Scienst C 27) Dr. M. Jha Scienst C 28) Mr. M. Raja Scienst C 29) Dr. S. Choudhry Scienst C 30) Dr. V. Bagchi Scienst C 31) Dr. D. Sharma Scienst B 32) Dr. N. Sardana Scienst B 33) Dr. R. Khan Scienst B 34) Dr. S. Lal Scienst B Dr. S. Boddu Scienst-B Dr. R. S.Dey Scienst-B Shri U. C Prasad CFAO Mrs Vibha Mehta Finance Officer

Ms. S. Belwal Stenographer Mr. R. Singh Stenographer Contractual administrave posions Mr. P K Daa Consultant and Head Projects Shri M. Jose Store and Purchase Officer Shri Niranjan Singh Chief Engineer Mr. J.N. Ahuja Chief Security Officer Contractual through outsourcing agency Mr. Surinder Singh Security Supervisor Security Guards at INST office 04 at INST Site 06

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20 Financial Statement AUDITORS' REPORT The Director, INSTITUTE OF NANO SCIENCE AND TECHNOLOGY MOHALI, Punjab

We have examined the aached Balance Sheet of INSTITUTE OF NANO SCIENCE AND TECHNOLOGY, MOHALI, Punjab as at March 31, 2018, Income and Expenditure Account and Receipt and Payment Account for the year ended March 31,2018. These Financial statements are the responsibility of the Instute's Management. Our responsibility is to express an opinion on these financial statements based on our audit. We conducted our audit in accordance with Auding Standards generally accepted in India. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatements. An audit includes examining on a test basis, evidence supporng the amounts and disclosures in financial statements. An audit also includes assessing the accounng principles used and significant esmates made by the management, as well as evaluang the overall financial statements presentaon. We believe that our audit provides a reasonable basis for our opinion.

We further report that: a) We have obtained all the informaon and explanaons which to the best our knowledge and belief were necessary for the purpose of our audit; b) In our opinion proper books of accounts, as required by law, have been kept by the instute so far as appears from our examinaon of those books; c) The Balance Sheet, Income and Expenditure Account and Receipt and Payment Account of the instute are in agreement with the books of account; d) In our opinion and to the best ofour informaon and according to the explanaons given to us, the said accounts read together with and subject to the Significant accounng Policies and Notes to Accounts thereon, give the informaon in the manner so required, and present a true and fair view in conformity with the accounng principles generally accepted in India; 1. In so far as it relates to Balance Sheet , of the state of affairs of the instute as at March 31, 2018; 2. In so far as it relates to the Income and Expenditure Account of the Excess of Expenditure over Income of the Instute for the period ended on that date.

For Agarwal A Kumar &Associates Chartered Accountants Place: Chandigarh Date:- 02/07/2018

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FINANCIAL STATEMENT INSTITUTE OF NANO SCIENCE AND TECHNOLOGY HABITAT CENTRE SECTOR-64 PHASE-X MOHALI PUNJAB

Schedule-15 Significant Accounng Policies

1. Accounng concepts & Basis of preparaon of Financial Statements The financial statements have been prepared under the historical cost convenon in accordance with the generally accepted accounng principles. The instute generally follows the accrual system of accounngand recognizes significant items of income & Expenditure on accrual basis unless otherwise stated.

2. Grants Grants are recognized on receipt, Grants received from Department of Science & Technology (DST) for Creaon of Capital Assets (plan) is treated as corpus of the centre. Grants received for General (Plan),General (ST),Salaries (Plan) and Salaries-SC (Plan) are treated as of revenue nature and shown under Income & Expenditure Account.

3. Fixed Assets and Depreciaon

No depreciaon on the Building has been charged during the year as these assets are not put to use upto 31.03.2018 as cerfied by the management of the Instute. Depreciaon on assets has been charged at the rates applicable under Income Tax Act. Depreciaon, on assets used for less than 180 days, is restricted to 50% of the prescribed rates. Cost of Fixed assets includes Custom Duty, Clearing & Forwarding Charges and Freight relang to such assets.

For Agarwal A Kumar & Associates Chartered Accountants

Place: Chandigarh Date: 02/07/2018

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FINANCIAL STATEMENT INSTITUTE OF NANO SCIENCE AND TECHNOLOGY HABITAT CENTRE SECTOR-64 PHASE-X MOHALI PUNJAB BALANCE SHEET AS AT MARCH 31, 2018 Amount in Rs CORPUS/CAPITAL FUND AND LIABILITES Schedules Current Year Previous Year

CORPUS/CAPITAL FUND 1 1117568511.72 652165179.70 RESERVE AND SURPLUS 2 -6678542.87 -9078220.75 EARMARKED/ENDOWMENT FUND 3 0.00 0.00 WELFARE FUND 3A 123793.00 50741.00 PROJECT ACCOUNT 3B 306329521.46 138826621.58 SECURED LOANS AND BORROWING 0.00 0.00 UNSECURED LOANS AND BORROWING 0.00 0.00 DEFERRED CREDIT LIABILITIES 0.00 0.00 CURRENT LIABILITIES & PROVISIONS 4 66202579.50 9797907.75 TOTAL 1483545862.81 791762229.28 ASSETS

FIXED ASSETS-INST 5 385827926.38 181793543.36 Fixed Assets-Project 5 69914793.42 4368674.30 INVESTMENT FROM EARMARKED/ENDOWMENT FUNDS 0.00 0.00 INVESTMENTS-OTHERS 6 0.00 0.00 CURRENT ASSETS, LOANS AND ADVANCES 1027803143.01 605600011.62 MISCELLANEOUS EXPENDITURE (to the extent 0.00 0.00 not written off or adjusted)

TOTAL 1483545862.81 791762229.28

SIGNIFICANT ACCOUNTING POLICIES 15 NOTES ON ACCOUNTS 16

105 Institute of Nano Science And Technology

Amount in Rs) INCOME Schedules Current Year Previous Year

1 Income from Sales and Services 7 1923081.00 1248434.00 2 Grants/subsides 8 160109000.00 189487333.00 3 Fees/subscripons 9 782189.00 575468.33 4 Interest 10 30190146.41 10059409.26 5 Other Misc Income/Receipts 11 3600108.23 2665869.82

TOTAL (A) 196604524.64 204036514.41

EXPENDITURE

1 Establishment Expenses 12 116150776.00 77686081.00 2 Other Expenses 13 78054070.76 36073512.00 3 Project Accounts 14 0.00 13663052.00

TOTAL (B) 194204846.76 127422645.00

Balance being excess/(shorall) of income over 2399677.88 76613869.41 Expenditure (A-B) carried forward to General Reserve

Depreciaon being adjusted from Capital Grant 37096667.98 28189325.92 Surplus/Deficit aer Depreciaon -34696990.10 48424543.49

For INSTITUTE OF NANO SCIENCE AND TECHNOLOGY

Vibha Mehta UMESH CHANDRA PRASAD As per our report of even date. Finance Officer Chief Finance & Administrave Officer

For Agarwal A Kumar & Associates Hirendra Nath Ghosh Chartered Accountants Director Place : Mohali Date : 02.07.2018

106 Institute of Nano Science And Technology

RECEIPT Current Year Previous Year PAYMENT Current Year Previous Year

Opening Balances Revenue Expenses a) Cash in Hand 0.00 20928.00 Establishment

As per Schedule 12 116150776.00 77686081.00 b) With Canara Bank Other Expenses In Current Account 105253.57 48661062.67 As per Schedule 13 78054070.76 36073512.00 In Deposit Account 585098148.05 122014597.21 Project Expenses Cheque Pending Realisaon 38129.00 76117.00 As per Schedule 14 28881761.41 13663052.00 Cheque Pending Realisaon- Project 24260.00 Employees Benevolent Account 50741.00 27316.00 Capital Expenditure

Grants Received on Fixed Assets Corpus/Capital Fund (As per Schedule-1) 502500000.0 0 345750000.0 0 As per Schedule 31864082 2.00 32444144.00 Revenue Fund (As per Schedule- Other 8 ) 160109000.00 189487333.00 Payments/Advances Projects Grant (As per Schedule (At the end of the 3B ) 198620835.00 33668579.00 year) Interest on F.D. from Projects Grants 9727478.17 5936968.58 Advance to Pares 28731592.00 16497.00 Welfare Fund 73052.00 23425.00 Advance to Staff 580323.00 332050.00 Interest Received Advance Projects 101617.00 0.00 Interest from Bank Deposits 30190146.41 10059409.26 T.D.S. Recoverable 621460.00 244845.00 Security fee As per Schedule deposited 1421088.00 1281088.00 Grant/fellowship receivable 90000.00 18409000.00 Fees Subscripons Received 782189.00 575468.33 Any Other Receipts (At the beginning of As per Sched ule the year) T.D.S. Payable 0.00 0.00 Cheques Pending Other Income (specify) 5523189.23 3914303.82 Encashment 1746277.00 1973438.00

As per Schedule Expenses Payable 6934395.75 2896384.00 Security/EMD Deposits 617235.00 84100.00 Other Payments/Advances Conference Receipts 500000.00 0 (At the beginning of the year) Closing Balances Advance to Pares 16497.00 141348.00 a) Cash in Hand 0.00 0.00 Adv ance to Staff 332050.00 35100.00 b) With Canara T.D.S. Recoverable 244845.00 116746.00 Bank

Security Fee 1281088.00 0.00 In Current Account 10927.08 105253.57 Advance (projects) 0.00 114113.00 In Deposit Account 995952463.93 585098148.05 Grant Receivable 18409000.00 0.00 In Employees 76546.00 50741.00

107 Institute of Nano Science And Technology

Benevolent Account Cheque Pending Realisaon 217126.00 38129.00 Security/EMD Deposits Cheque Pending Received 3105565.00 617235.00 Realisaon-Project 0.00 24260.00

Any Other Receipts (At the end of the year) Conference Receipts 0.00 500000.00 Cheques Pending Encashment- INST 3334570.00 1622568.00 Cheques Pending Encashment- Projects 662844.34 123709.00 Expenses Payable 59099600.16 6934395.75

1579328480.93 770420722.62 1579328480.93 770420722.62

For INSTITUTE OF NANO SCIENCE AND TECHNOLOGY

Vibha Mehta UMESH CHANDRA PRASAD As per our report of even date. Finance Officer Chief Finance & Administrave Officer

For Agarwal A Kumar & Associates Hirendra Nath Ghosh Chartered Accountants Director Place : Mohali Date : 02.07.2018

108

Institute of Nano Science And Technology

SCHEDULE NO. -1

Amount in Rs)

CURRENT YEAR PREVIOUS YEAR CORPUS/CAPITAL FUND Contribuon towards creaon of corpus fund Balance at the beginning of the year 652165179.70 334604505.62 Add: Addion during the year (DST) 502500000.00 345750000.00 Less: Depreciaon on fixed Assets 37096667.98 28189325.92 BALANCE AT THE YEAR END 1117568511.72 652165179.70

SCHEDULE NO. -2

Amount in Rs)

CURRENT YEAR PREVIOUS YEAR RESERVE AND SURPLUS General Reserve Balance at the beginning of the year -9078220.75 -85692090.16 Add: Addion during the year - transfer from Income & 2399677.88 76613869.41 Expenditure Account Less : Deducon during the year - Transfer from Income & 0.00 0.00 Expenditure Account

BALANCE AT THE YEAR END -6678542.87 -9078220.75

SCHEDULE NO. -3A

Amount in Rs)

CURRENT YEAR PREVIOUS YEAR WELFARE FUND Benevolent Fund Opening Balance 50741.00 0 Employees Benevolent Fund 23600.00 48600.00 Interest on Employees Benevolent Fund 2205.00 2141.00

TOTAL 76546.00 50741.00 Employee Welfare Benevolent Fund from OHs 5997.00 0 of Consultancy Projects INST Overheads Fund from Consultancy 19250.00 0 Projects IPR Cell Fund from Ohs of Consultancy Projects 8250.00 0 Outreach Programme Fund from Ohs of 5500.00 0 Consultancy Projects Scienst PDA Share Fund from Ohs of 8250.00 0 Consultancy Projects

Total 123793.00 50741.00

109

Institute of Nano Science And Technology

SCHEDULE NO. -3B

Amount in Rs)

CURRENT YEAR PREVIOUS YEAR PROJECT ACCOUNT DBT Project 10836179.00 569656.00 Grant from DIHAR 1920850.00 1981200.00 SERB Project 66359959.00 45831737.00 Hindu college Delhi (Project sponsored by DST) 1569590.00 1600000.00 DST Project 246997752.00 79080902.00 Grant UGC-DAE 45000.00 45000.00 Interest on F.D. from Projects Grants 17364381.75 7636903.58 Interest on Bank Account 2081223.00 2081223.00 TOTAL 347174934.75 138826621.58 Less: Expenditure from Project Grants (Schedule 14) 40845413.29 0.00 Net Grants 306329521.46 138826621.58 SCHEDULE NO. -4 Amount in Rs)

CURRENT YEAR PREVIOUS YEAR

CURRENT LIABILITIES AND PROVISIONS

A. CURRENT LIABILITIES

1. Subscripon received for Conference 0.00 500000.00 2. Cheques Pending Encashment- INST 3334570.00 1622568.00 3. Cheques Pending Encashment- Projects 662844.34 123709.00 4. GIS Payable 120.00 603.00 5. Medical Subscripon Payable 0.00 675.00 6. Provident Fund Payable 0.00 15000.00 7. Salary Payable - INST 13695022.00 2915353.00 9. Security/Earnest Money Deposits 3105565.00 617235.00 10. NPS Subscripon 3030660.00 600246.00 11. Benevolent Fund 2000.00 1950.00 12. Audit fees payable 29500.00 28750.00 13. CHSS 0.00 1827.00 14. GPF 17740.00 17740.00 15. EMD Deposit 8485238.75 3352251.75 16. GST 1170.00 0.00 17. Consultancy Fee IND-02 167000.00 0.00 18. Grant received for NPDF Fellows 2060772.00 0.00 19. Grant INSPIRE FACULTY 1186007.00 0.00 20. Grant Nano Mission School 234224.00 0.00 Interest Received during 2017-18 on GIA from 30190146.41 0.00 DST Refundable to DST TOTAL (A) 66202579.50 9797907.75 B. PROVISIONS 1. Other 0.00 0.00 TOTAL (B) 0.00 0.00 TOTAL (A+B) 66202579.50 9797907.75

110 Institute of Nano Science And Technology

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111

Institute of Nano Science And Technology

SCHEDULE NO. -6 Amount in Rs)

CURRENT YEAR PREVIOUS YEAR

CURRENT ASSETS, LOANS & ADVANCES

A. CURRENT ASSETS

1 Cash in Hand 0.00 0.00

2 Bank Balances Canara Bank a) Curr ent Account No. 2452201001102- INST 5125.17 5252.75 b) Auto Sweep/F.D. Accounts-INST 784048848.9 4 473653066.47 c) Current Account No.2919201000578- Projects 5801.91 100000.82 d) Auto Sweep/F.D. Accounts-Projects 211903614.99 111445081.58 585203401.62

e) Benevolent Account No. 2919101002412 76546.00 996039937.01 50741.00

3 Cheque Pending Realisaon-INST 217126.00 38129.00

4 Cheque Pending Realisaon-Project 0 24260.00

TOTAL: (A) 996257063.01 585316531.62

LOANS, ADVANCES/DEPOSITS AND OTHER B ASSETS ETC. Advance to pares 7195475.00 16497.00 INSA vising scienst felowship receivable 90000.00 Secured Advance for Building 21536117.00 Advance to Staff 580323.00 332050.00 Advance to staff (INST Projects) 101617.00 0.00 Tax Deducted at Source-INST 510025.00 212505.00

Tax Deducted at Source-Project 111435.00 32340.00

SECURITY FEE Deposited 1421088.00 1281088.00

Grant Receivable 0.00 18409000.00

TOTAL (B) 31546080.00 20283480.00

TOTAL (A+B) 1027803143.01 605600011.62

112 Institute of Nano Science And Technology

SCHEDULE NO. -7 Amount in Rs)

Current Year Previous Year INCOME FROM SALES & SERVICES

1 Consultancy Project 1923081.00 1248434.00

TOTAL 1923081.00 1248434.00

SCHEDULE NO. -8 Amount in Rs)

Current Year Previous Year GRANTS/SUBSIDIES 1 Grant for salaries RTFDDCS training programme 0.00 237333.00 2 Grant in Aid General (Plan) 48230000.00 59463000.00 3 Grant in Aid Salaries (Plan) 95626000.00 120687000.00 4 Grant in Aid Salaries-SC 4100000.00 4100000.00 5 Grant in Aid General (ST) 12153000.00 5000000.00

TOTAL 160109000.00 189487333.00 SCHEDULE NO. -9 Amount in Rs)

Current Year Previous Year FEES/SUBSCRIPTIONS

1 Applicaon Fee 210850.00 275217.46 2 RTI Fee 50.00 10.00 3 Tender Fee 262000.00 48055.87 4 Admission Fee 182289.00 156185.00 5 License Fees 72000.00 96000.00 6 Internship Fees 55000.00 0.00 TOTAL 782189.00 575468.33

113 Institute of Nano Science And Technology

SCHEDUAmounLEt inNO Rs. -10)

Current Year Previous Year INTEREST EARNED

1 On Term Deposits 1. INST Main 30190146.41 10059409.26

TOTAL 30190146.41 10059409.26

SCHEDULE NO. -11 Amount in Rs)

Current Year Previous Year OTHER MISCELLANEOUS INCOME/RECEIPTS

1 Guest House Receipts 131400.00 69400.00 2 Outreach Programme Receipts 0.00 242000.00 3 Overhead receipt 3160328.00 2089878.00 4 Penal Interest- INST 769.00 1108.00 5 Penal Interest- Projects 0.00 630.00 6 Miscellaneous Receipts-INST 258895.34 221825.00 7 Miscellaneous Receipts-Projects 48715.89 1251.82 8 Sample tesng 0.00 39777.00

TOTAL 3600108.23 2665869.82 SCHEDULE NO. -12

Amount in Rs) Current Year Previous Year ESTABLISHMENT EXPENSES 1 P ay and Allowances 67422176.00 43208462.00 2 Composite Transfer Grant 241428.00 0.00 3 Salary and Wages 11292482.00 7111632.00 4 Salary consultants 2505436.00 3024511.00 5 Salary IND002 0.00 25500.00

6 Salary INST Project 175000.00 432893.00 7 Salary & Conngency of Post DOC 3053640.00 5507526.00 8 Salary/Spend & Conngency of Ph.D Students 27948636.00 14894647.00

9 Salary Dr. Ehsan Student 188367.00 0.00 10 Children Educaon Allowance 211500.00 195000.00 11 LTC 1882453.00 2239072.00

12 Leave Salary Encashment 186832.00 276589.00 13 Medi cal Reimbursement Expenses 1042826.00 770249.00 TOTAL 116150776.00 77686081.00

114

Institute of Nano Science And Technology

SCHEDULE NO. -13 Amount in Rs)

Current Year Previous Year OTHER EXPENSES

1 ADVERTISEMENT AND PUBLICITY 1237957.00 616459.00 2 ADVERTISEMENT EXP. IND-05 4257.00 0.00 3 FREIGHT AND CARTAGE 65980.00 115670.00 4 ELECTRICITY/POWER SUPPLY CHARGES 3587952.00 2556880.00 5 CUSTOM DUTY & CLEARANCE 1013446.00 568949.00 6 RENT TO GMADA, CIAB & NABI 12180603.00 12665391.00 7 POS MACHINE RENT 4779.00 0.00 8 REPAIR AND MAINTENANCE 297782.00 600649.00 9 AUDIT FEE 29500.00 28750.00 10 GUEST HOUSE EXPENSES 0.00 280.00 11 PRINTING AND STATIONERY 854455.00 1247595.00 12 CONVEYANCE 2074415.00 1839323.00 13 CO-PI CONSULTANCY SHARE IND-01 58100.00 0.00 14 CO-PI CONSULTANCY SHARE IND-02 80284.00 0.00 15 POSTAGE AND STAMPS 286496.00 189971.00 16 MISCELLANEOUS EXPENSES 71574.00 149351.00 17 BANK CHARGES 489612.60 93970.00 18 LEGAL, PROFESSIONAL CHARGES 124049.00 54376.00 19 HONORARIUM PAID 479733.00 481276.00 20 HORTICULTURE, GARDENING & PLANTATION 54163.00 21693.00 21 LABOUR AND PROCESSING EXPENSES 26008.00 31200.00 22 MEETING EXPENSES 208645.00 134707.00 23 OFFICE EXPENSES 73273.00 48441.00 24 TELEPHONE EXPENSES 447523.00 483985.00 25 COMPUTER REPAIR AND MAINTENANCE 108450.00 87746.00 26 CONFERENCE EXPENSES 1079665.00 609077.00 27 CONSUMABLE STORES 341430.00 132618.00 28 MEMBERSHIP FEES 6849.00 14413.00 29 DIESEL FOR GENERATOR SET 220387.00 94089.00 30 EXHIBITION BOOKING CHARGES 520430.00 0.00 31 INTERNET EXPENSES 200057.00 314706.00 32 NEWSPAPERS AND PERIODICALS 35474.00 24051.00 33 PATENT FILLING 38600.00 7500.00 34 REGISTRATION FEE 78300.00 0.00 35 WEB HOSTING 98176.00 0.00 36 ACCOMMODATION EXPENSES 242393.00 19910.00 37 FOUNDATION DAY AWARD 278267.00 245023.00 38 OUTREACH PROGRAMME EXPENSES 684306.00 329784.00

39 HOSPITALITY AND STAFF WELFARE 91749.33 61879.00

115 Institute of Nano Science And Technology

40 RTF-DCS FELLOWSHIP PAYMENT 137895.00 35000.00 41 LAB CHEMICALS 8590924.25 7652006.00 42 LAB CHEMICALS INST PROJECT 01 95693.00 0.00 43 LAB CHEMICAL POST DOC 11714.00 0.00 44 CANTEEN ACCOUNT 123445.00 66811.00 45 CAUTION MONEY 8000.00 0.00 46 OVERHEAD EXPENSE 2590357.00 416451.00 47 SERVICE TAX PENALTY 639.00 65.00 48 SPORTS DAY 121316.00 93242.00 49 PDA EXPENSE TO FACULTY 30093.00 54868.00 50 TA/DA 2544844.00 3144699.00 51 TA/DA IND-03 10103.00 0.00 52 TA/DA IND-04 13313.00 0.00 53 TA/DA INST-03 10228.00 0.00 54 USAGE CHARGES OF IISER EQUIPMENT 0.00 60000.00 55 WATER CHARGES 47273.00 91890.00 56 NSAG MEETING EXP. 0.00 28996.00 57 INST PROJECT 03 LAB CHEMICALS 63774.25 426312.00 58 INST PROJECT 02 LAB CHEMICALS 0.00 73460.00 59 CONSULTANCY PROJECT EXPENSES 610114.00 60000.00 60 DIGITAL SIGNATURE EXPENDITURE 30912.00 0.00 61 INHOUSE SYMPOSIUM EXPENSES 193741.00 0.00 62 RETAINERSHIP FEES 63000.00 0.00 63 ROAD SHOW 157087.00 0.00 64 SAMPLE TESTING 82616.00 0.00 65 SWACHHTA HI SEWA MISSION 75334.00 0.00 66 ADMN FUND CONSULTANCY SHARE IND-02 6400.00 0.00 67 ADMN FUND CONSULTANCY SHARE IND-01 9000.00 0.00 68 MENTOR-CONSULTANCY SHARE IND-02 20988.00 0.00 69 MENTOR-CONSULTANCY SHARE IND-01 13700.00 0.00 70 PI-CONSULTANCY SHARE IND-01 91300.00 0.00 71 PI-CONSULTANCY SHARE IND-02 122862.00 0.00 72 RESEARCH CONTINGENCY OF FACULTY 122092.00 0.00 73 EXPENDITURE OUT OF GENERAL (ST) 3981429.00 0.00 74 INTEREST 1237.00 0.00 75 NFD CONFERENCE 36459.00 0.00 76 INTEREST ON GIA RECEIVED FROM DST REFUNDABLE TO DST 30190146.41 0.00 77 INTEREST ON PREMATURE REDEMPTION OF FD 70921.92 0.00 TOTAL 78054070.76 36073512.00

116 Institute of Nano Science And Technology

SCHEDULE NO. -14 Amount in Rs)

Current Year Previous Year PROJECT ACCOUNT-EXPENDITURE

1 Adversement and Publicity 310616.00 70486.00 2 Bank Charges 164101.55 275522.00 3 Canteen 0.00 630.00 4 Conngency 1108485.00 382336.00 5 Lab Chemicals 12415788.50 6172340.00 6 Miscellaneous expense 57405.00 11960.00 7 Overhead Expenses 4496044.00 1200969.00 8 Prinng & Staonery 1200.00 0.00 9 Registraon Fee 55143.00 0.00 10 Salary- Project 8592142.00 5149966.00 11 T.A./ D.A. 590997.00 320252.00 12 Custom Charges 268552.00 27151.00 13 Freight Charges 58765.00 13425.00 RTF -DCS Lab Chemical- 14 Project 0.00 38015.00 15 Fellowship- RP42 Indo Australian Project 680000.00 0.00 16 Honorarium RP-41 75667.00 0.00 17 Rent POS Machine 6855.36 0.00 18 Depreciaon on Project Assets 11963651.88 0.00 TOTAL 40845413.29 13663052.00

117 Institute of Nano Science And Technology

LIST OF ADVANCE TO PARTIES AS ON 31.03.2018

(Amount in Rs.) Current Year Previous Year M/s Parkash Freight Movers 16497.00 16497.00 M/s JNCASR, Banglore 150000.00 0.00 M/s Airport Handling 7025418.00 0.00 M/s ARCI-NANOTECH INSIGHTS 2000.00 0.00 M/s India Today 1560.00 0.00 Secured Advance for Building 21536117.00 0.00 TOTAL 28731592.00 16497.00

(Amount in Rs.) Current Year Previous Year Dr. Debabarata Patra 6409.00 0.00 Dr. Jayamurugan 167628.00 0.00 Dr. KamalkammamKailasam 13888.00 0.00 Dr. Kaushik Ghosh 126802.00 0.00 Dr. Manish 69300.00 0.00 Dr. Menaka 10000.00 100000.00 Dr. P.S. Vijaya Kumar 4777.00 0.00 Dr. Rahul Verma 9038.00 1000.00 Dr. Sangita 146422.00 0.00 Dr. Sanyasinaidu Boddu 2479.00 Dr. Surajit Karmakar 3200.00 10000.00 Sh. Dhanjit Singh 10000.00 10000.00 Sh. J.N. Ahuja 380.00 Sh. Surinder Singh 10000.00 10050.00 Dr. Deepa Ghose 0.00 10000.00 Dr. Ehsan Ali 0.00 191000.00 TOTAL 580323.00 332050.00

(Amount in Rs.) Current Year Previous Year Dr. Asif Khan 70000.00 0.00 Dr. Jayamurugan 2478.00 0.00 Dr. KamalkammamKailasam 5139.00 0.00 Dr. Kaushik Ghosh 23800.00 0.00 Dr. Manish 200.00 0.00 INST MAIN ACCOUNT 0.00 TOTAL 101617.00 0.00

118 Institute of Nano Science And Technology

FINANCIAL STATEMENT INSTITUTE OF NANO SCIENCE AND TECHNOLOGY HABITAT CENTRE SECTOR-64 PHASE-X MOHALI PUNJAB

Schedules- 16 Notes to the Accounts

1. Department of Science and Technology (DST) Sanconed and Released dring the 2016- 17, total Grant of Rs. 5350 Lakhs. During the previous year 2017-18, Rs 6626.09 Lakhs were received as per following detail:

Rs. In Lakhs Æ Grant in Aid Creaon of Capital Assets (Plan) 1025.00 Æ Grant in Aid Construcon of INST Campus 4000.00 Æ Grant in Aid General (Plan) 482.30 Æ Grant in Aid Salaries (Plan) 956.26 Æ Grant in Aid Salaries- SC(Plan) 41.00 Æ Grant in Aid General (ST) 121.53 6626.09

As cerfied by the management of the Instute, the Grant in Aid Creaon of Capital Assets (Plan) & Construcon of INST Campus of Rs. 5025.00 Lakhs has been shown as Corpus/Capital Fund and all the remaining Grants amounng of Rs. 1601.09 Lakhs has been shown as of revenue nature under Income & Expenditure Account. As cerfied by the management of the Instute, the enre Grant in aid of Rs. 5025.00 Lakhs released under Capital Head has been ulized for creaon of Capital Assets and hence capitalized in the Balance Sheet.

As cerfied by the management of the instute, total of Rs. 19,86,20,835.00 has been received as Grant in Aid for various projects upto 31.03.2018, which has been incorporated in the final accounts of the Instute.

During the year Rs. 23600.00 has been contributed as Benevolent Fund by the employees of the Instute which has been incorporated in the final accounts of the Instute.

2. The financial statements have been prepared under the historical cost convenon in accordance with the generally accepted accounng principles. The Instute generally follows accrual system of accounng and recognizes significant items of Income& Expenditure on accrual basis unless otherwise stated as cerfied by the management of the Instute. 3. In the opinion of the management the current assets, loans and advances are approximately of the value stated, if realized in the ordinary course of business. The provision of all the known liabilies is adequate and not excess of the amount considered reasonable and necessary.

119 Institute of Nano Science And Technology

1. No depreciaon on the Building has been charged during the year as these assets are not put to use up to 31.03.2018 as cerfied by the management of the Instute. Depreciaon on assets has been charged at the rates applicable under Income Tax Act. Depreciaon, on assets used for less than 180 days, is restricted to 50% of the prescribed rates. Cost of Fixed Assets includes Custom Duty, Clearing& Forwarding charges and Freight relang to such assets. 2. As cerfied by the management of the Instute that the cost of all Laboratory Chemicals of Rs. 2,11,77,894.00 purchased during the year 2017-2018 has been issued to laboratory and the same has been consumed up to 31.03.2018. Hence total cost of Rs. 2,11,77,894.00 has been charged to Income & Expenditure Account/Project Account. 3. Cash in Hand, Bank Balances and Fixed Deposit Balances as on 31.03.2018 shown in the Balance Sheet are as cerfied by the management of the Instute. 4. The Interest earned and accrued during the year shown as Income in the Income & Expenditure Account is as cerfied by the management of the Instute. 5. The depreciaon has been charged to Capital fund instead of Income & Expenditure Account 6. Previous year figures have been regrouped/rearranged where ever considered necessary. 7. All Schedules form an integral part of the Balance Sheet and Income& Expenditure Account and have been duly authencated by the management of the Instute. 8. All interests and other earning against Grant in aid or advances to be returned to DST as per their instrucons. For Agarwal & Associates Chartered Accountants Place: Mohali Date: 02/07/2018 Vibha Mehta UMESH CHANDRA PRASAD Finance officer Chief Finance & Administrave Officer

Hirendra Nath Ghosh Director

120 okf’kZd izfrosnu ANNUAL REPORT 2017 - 2018

INSTITUTE OF NANO SCIENCE AND TECHNOLOGY (An Autonomous Institute of Department of Science and Technology, Govt. of India)

Habitat Centre, Phase-10, Sector-64 Mohali, Punjab-160062 Email ID: [email protected] ANNUAL REPORT Website: www.inst.ac.in 2017-18