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Lung Transplantation with the OCS (Organ Care System)
Lung Transplantation with the OCSTM (Organ Care System) Lung System Bringing Breathing Lung Preservation to Transplant Patients A Guide for You and Your Family DRAFT ABOUT THIS BOOKLET This booklet was created for patients like you who have been diagnosed with end-stage lung failure and are candidates for a lung transplant. It contains information that will help you and your family learn about options available to you for a transplant. This booklet includes information on your lungs, how they function, and respiratory failure. In addition, you will learn about a new way to preserve lungs before transplantation, called breathing lung preservation. Your doctor is the best person to explain your treatment options and their risks and to help you decide which option is right for you. The booklet explains: • Breathing lung preservation with the OCS™ Lung System • How the OCS™ Lung System works • Who is eligible for the OCS™ Lung System • Lung transplant complications • How the lungs function • What is respiratory failure and the treatment options • What to expect during your treatment • Summary of clinical data for the OCS™ Lung System • Contact Information Please read this booklet carefully and share it with your family and caregivers. For your convenience, a glossary is provided in the front of this booklet. Terms in the text in bold italics are explained in the glossary. If you have questions about the OCS™ Lung System that are not answered in this booklet, please ask your physician. This booklet is intended for general information only. It is not intended to tell you everything you need to know about a lung transplant. -
Case Report AJNT
Arab Journal of Nephrology and Transplantation. 2011 Sep;4(3):155-8 Case Report AJNT High Ureteric Injury Following Multiorgan Recovery: Successful Kidney Transplant with Boari Flap Ureterocystostomy Reconstruction Michael Charlesworth*, Gabriele Marangoni, Niaz Ahmad Department of Transplantation, Division of Surgery, St James’s University Hospital, Leeds, United Kingdom Abstract Keywords: Kidney; Transplant; Ureter; Donor efficiency Introduction: Despite increased utilization of marginal organs, there is still a marked disparity between organ The authors declared no conflict of interest supply and demand for transplantation. To maximize resources, it is imperative that procured organs are in Introduction good condition. Surgical damage at organ recovery can happen and organs are sometimes discarded as a result. Despite the extension of the donor pool with the inclusion We describe a damaged recovered kidney with high of marginal organs and the use of organs donated after ureteric transection that was successfully transplanted cardiac death, there is still a great disparity between the using a primary Boari flap ureterocystostomy. number of patients on the transplant waiting list and the number of kidney transplants performed each year. Case report: The donor kidney was procured form a It is therefore of paramount importance to maximize deceased donor and sustained damage by transection our scarce resources and avoid the discard of otherwise of the ureter just distal to the pelvi-ureteric junction at functional kidneys due to iatrogenic injuries at the time organ recovery. The recipient had been on the transplant of multi-organ recovery. Essentially, three types of organ waiting list for eight years and not accepting this kidney damage can potentially occur: vascular, parenchymal would have seriously jeopardized her chance of future and ureteric. -
Pelvic Anatomyanatomy
PelvicPelvic AnatomyAnatomy RobertRobert E.E. Gutman,Gutman, MDMD ObjectivesObjectives UnderstandUnderstand pelvicpelvic anatomyanatomy Organs and structures of the female pelvis Vascular Supply Neurologic supply Pelvic and retroperitoneal contents and spaces Bony structures Connective tissue (fascia, ligaments) Pelvic floor and abdominal musculature DescribeDescribe functionalfunctional anatomyanatomy andand relevantrelevant pathophysiologypathophysiology Pelvic support Urinary continence Fecal continence AbdominalAbdominal WallWall RectusRectus FasciaFascia LayersLayers WhatWhat areare thethe layerslayers ofof thethe rectusrectus fasciafascia AboveAbove thethe arcuatearcuate line?line? BelowBelow thethe arcuatearcuate line?line? MedianMedial umbilicalumbilical fold Lateralligaments umbilical & folds folds BonyBony AnatomyAnatomy andand LigamentsLigaments BonyBony PelvisPelvis TheThe bonybony pelvispelvis isis comprisedcomprised ofof 22 innominateinnominate bones,bones, thethe sacrum,sacrum, andand thethe coccyx.coccyx. WhatWhat 33 piecespieces fusefuse toto makemake thethe InnominateInnominate bone?bone? PubisPubis IschiumIschium IliumIlium ClinicalClinical PelvimetryPelvimetry WhichWhich measurementsmeasurements thatthat cancan bebe mademade onon exam?exam? InletInlet DiagonalDiagonal ConjugateConjugate MidplaneMidplane InterspinousInterspinous diameterdiameter OutletOutlet TransverseTransverse diameterdiameter ((intertuberousintertuberous)) andand APAP diameterdiameter ((symphysissymphysis toto coccyx)coccyx) -
The Human Body Systems for Kids
1 Maine Regional School Unit #67 Chester, Lincoln, Mattawamkeag The Human Body Systems for Kids KidsKonnect.com and kidshealth.org provide links to more detailed information about each of the systems listed below. The first group of systems are commonly taught in the elementary grades. Teachers wishing more detailed information should consult sources beyond this handout. There are many systems in the human body. • Skeletal System (bones) • Respiratory System (nose, trachea, lungs) • Circulatory System (heart, blood, vessels) • Digestive System (mouth, esophogus, stomach, intestines) • Muscular System (muscles) • Nervous System (brain, spinal cord, nerves) • Excretory System (lungs, large intestine, kidneys) • Urinary System (bladder, kidneys) • Endocrine System (glands) • Reproductive System (male and female reproductive organs) • Immune System (many types of protein, cells, organs, tissues) 2 The Skeletal System has three major jobs: • It protects our vital organs such as the brain, the heart, and the lungs. • It gives us the shape that we have. • It allows us to move. Because muscles are attached to bones, when muscles move, they move the bones and the body moves. http://kidshealth.org/kid/htbw/bones.html The Respiratory System is the system of the body that deals with breathing. When we breathe, the body takes in the oxygen that it needs and removes the carbon dioxide that it doesn't need. The organ most closely connected with this system is the lung. The human body has two lungs. http://kidshealth.org/kid/htbw/lungs.html 3 The Circulatory System is the system by which oxygen and nutrients reach the body's cells, and waste materials are carried away. -
The Muscular System
THE MUSCULAR SYSTEM COMPILED BY HOWIE BAUM 1 Muscles make up the bulk of the body and account for 1/3 of its weight.!! Blood vessels and nerves run to every muscle, helping control and regulate each muscle’s function. The muscular system creates body heat and also moves the: Bones of the Skeletal system Food through Digestive system Blood through the Circulatory system Fluids through the Excretory system MUSCLE TISSUE The body has 3 main types of muscle tissue 1) Skeletal, 2) Smooth, and 3) Cardiac SKELETAL MUSCLE SMOOTH MUSCLE CARDIAC MUSCLE Skeletal muscles attach to and move bones by contracting and relaxing in response to voluntary messages from the nervous system. Skeletal muscle tissue is composed of long cells called muscle fibers that have a striated appearance. Muscle fibers are organized into bundles supplied by blood vessels and innervated by motor neurons. Muscle structure Skeletal (striated or voluntary) muscle consists of densely packed groups of hugely elongated cells known as myofibers. These are grouped into bundles (fascicles). A typical myofiber is 2–3 centimeters ( 3/4–1 1/5 in) long and 0.05millimeters (1/500 inch) in diameter and is composed of narrower structures – myofibrils. These contain thick and thin myofilaments made up mainly of the proteins actin and myosin. Numerous capillaries keep the muscle supplied with the oxygen and glucose needed to fuel contraction. Skeletal Muscles • Skeletal muscles attach to bones by tendons (connective tissue) and enable movement. • Skeletal muscles are mostly voluntary Feel the back of your ankle to feel your Achilles tendon - the largest tendon in your body. -
Internet Research Sites
Human Body Project Helpful Sites General Sites www.exploratorium.edu http://www.ehc.com/vbody.asp A virtual body tour (brain, skeleton, heart, and digestive tract). http://www.kidsbiology.com/human_biology/index.php A kid-friendly site that allows you to explore your body under one of the human body systems. Ophthalmologists- Muscular System http://www.exploratorium.edu/learning_studio/cow_eye/coweye.pdf Step by step directions on cow eye dissection. http://www.exploratorium.edu/learning_studio/cow_eye/ -Cow eye dissection video. Cardiologists- Circulatory System Cardiovascular System Circulatory System Circulatory System 1 Circulatory System: The Life Pump How Your Heart Works Kids Health: Your Heart & Circulatory System Preview the Heart The Circulatory System The Human Heart Wikipedia: The Circulatory System Orthopedic Specialist-Skeletal System http://kidshealth.org/kid/htbw/bones.html Multi-media Flash videos and information on bones. eSkeletons Project Human Skeleton Printout-Enchanted Learning.com Kids Health: Your Bones Skeletal System Skeletal System: The Bone Zone Skeletal System (Front View) Skeletal System (Back View) The Skeletal System The Skeleton Wikipedia: Skeleton Pulmonary Specialist- Respiratory System http://kidshealth.org/kid/closet/movies/asthma_movie.html Flash video showing Asthma’s effect on our lungs. Air Bags: The Respiratory System How the Body Works: The Respiratory System Kids Health: Your Lungs & Respiratory System Oxygen Delivery System Respiratory System The Respiratory System Your Respiratory System -
Science-5-Nov-16-20 Circulatory-System.Pdf
Grade 5 Science Week of November 16 – November 20 Circulatory System Most of the cells inside of your body do not move. If a cell is hungry or needs to get rid of waste, it can’t simply move itself to the part of your body where it needs to go. Instead, your body must bring the food to your cells and take the waste away from them. By using billions of tiny tubes the circulatory system transports substances around our bodies. It delivers essential nutrients to every cell, and it transports waste products to waste-disposal sites—the lungs, the skin, and the kidneys. The circulatory system is an organ system that includes the heart, the blood vessels, and the blood itself. It has three functions: 1. to transport materials (i.e., nutrients and oxygen) and cells from one place to another 2. to defend the body against invasion by harmful organisms by taking white blood cells to an area of injury or infection 3. to maintain a constant body temperature Introduction Your body has a network of blood vessels—hollow tubes—that move blood and nutrients. A pumping organ—the heart—pushes blood through this network of vessels. Watch this video to start looking at this incredible system: https://youtu.be/tF9-jLZNM10 Complete the following. 1) Fill in the blanks: 1. Most of the cells inside of your body ________________ . If a cell is _____________ or needs to get rid of ______________, it can’t simply move itself to the part of your body where it needs to go. -
Skin Is Not the Largest Organ
View metadata, citation and similar papers at core.ac.uk brought to you by CORE providedRD by Elsevier Sontheimer - Publisher Connector Skin is Not the Largest Organ 3 content. CHS, JNB, and MAS were involved in Paris, France; Division of Genetics and susceptibility to psoriasis vulgaris. J Invest study supervision. Molecular Medicine, St John’s Institute of Dermatol 134:271–3 Dermatology, Guy’s Hospital, London, UK; Martin MA, Klein TE, Dong BJ et al. (2012) Clinical 1,8 4 Alexander A. Navarini , Guy’s and St Thomas’ NHS Foundation pharmacogenetics implementation consortium Trust, Skin Therapy Research Unit, St John’s Laurence Valeyrie-Allanore2,8, guidelines for HLA-B genotype and abacavir 1 Institute of Dermatology, St Thomas’ Hospital, dosing. Clin Pharmacol Ther 91:734–8 Niovi Setta-Kaffetzi , London, UK; 5King’s College Hospital, London, Jonathan N. Barker1,3,4, UK; 6University Medical Center Freiburg, Navarini AA, Valeyrie-Allanore L, Setta-Kaffetzi N et al. (2013) Rare variations in IL36RN in 1 5 Institute of Medical Biometry and Medical Francesca Capon , Daniel Creamer , severe adverse drug reactions manifesting as 2 6 Informatics, Freiburg, Germany and Jean-Claude Roujeau , Peggy Sekula , 7 acute generalized exanthematous pustulosis. 1 Department of Dermatology, J Invest Dermatol 133:1904–7 Michael A. Simpson , Dokumentationszentrum Schwerer 1 Richard C. Trembath , Hautreaktionen (dZh), Universita¨ts-Hautklinik, Setta-Kaffetzi N, Navarini AA, Patel VM et al. (2013) Maja Mockenhaupt7,8 and Freiburg, Germany Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated 1,3,4,8 8 Catherine H. Smith These authors contributed equally to this work. -
GLOSSARY of MEDICAL and ANATOMICAL TERMS
GLOSSARY of MEDICAL and ANATOMICAL TERMS Abbreviations: • A. Arabic • abb. = abbreviation • c. circa = about • F. French • adj. adjective • G. Greek • Ge. German • cf. compare • L. Latin • dim. = diminutive • OF. Old French • ( ) plural form in brackets A-band abb. of anisotropic band G. anisos = unequal + tropos = turning; meaning having not equal properties in every direction; transverse bands in living skeletal muscle which rotate the plane of polarised light, cf. I-band. Abbé, Ernst. 1840-1905. German physicist; mathematical analysis of optics as a basis for constructing better microscopes; devised oil immersion lens; Abbé condenser. absorption L. absorbere = to suck up. acervulus L. = sand, gritty; brain sand (cf. psammoma body). acetylcholine an ester of choline found in many tissue, synapses & neuromuscular junctions, where it is a neural transmitter. acetylcholinesterase enzyme at motor end-plate responsible for rapid destruction of acetylcholine, a neurotransmitter. acidophilic adj. L. acidus = sour + G. philein = to love; affinity for an acidic dye, such as eosin staining cytoplasmic proteins. acinus (-i) L. = a juicy berry, a grape; applied to small, rounded terminal secretory units of compound exocrine glands that have a small lumen (adj. acinar). acrosome G. akron = extremity + soma = body; head of spermatozoon. actin polymer protein filament found in the intracellular cytoskeleton, particularly in the thin (I-) bands of striated muscle. adenohypophysis G. ade = an acorn + hypophyses = an undergrowth; anterior lobe of hypophysis (cf. pituitary). adenoid G. " + -oeides = in form of; in the form of a gland, glandular; the pharyngeal tonsil. adipocyte L. adeps = fat (of an animal) + G. kytos = a container; cells responsible for storage and metabolism of lipids, found in white fat and brown fat. -
A Description of the Omo I Postcranial Skeleton, Including Newly Discovered Fossils
Journal of Human Evolution 55 (2008) 421–437 Contents lists available at ScienceDirect Journal of Human Evolution journal homepage: www.elsevier.com/locate/jhevol A description of the Omo I postcranial skeleton, including newly discovered fossils Osbjorn M. Pearson a,*, Danielle F. Royer b, Frederick E. Grine c,d, John G. Fleagle c a Department of Anthropology, MSC 01-1040, University of New Mexico, Albuquerque, NM 87131, USA b Interdepartmental Doctoral Program in Anthropological Sciences, Stony Brook University, Stony Brook, NY 11794, USA c Department of Anatomical Sciences, Stony Brook University, Stony Brook, NY 11794, USA d Department of Anthropology, Stony Brook University, Stony Brook, NY 11794, USA article info abstract Article history: Recent fieldwork in the Kibish Formation has expanded our knowledge of the geological, archaeological, Received 24 April 2007 and faunal context of the Omo I skeleton, the earliest known anatomically modern human. In the course Accepted 15 May 2008 of this fieldwork, several additional fragments of the skeleton were recovered: a middle manual phalanx, a distal manual phalanx, a right talus, a large and a small fragment of the left os coxae, a portion of the Keywords: distal diaphysis of the right femur that conjoins with the distal epiphysis recovered in 1967, and a costal Anatomically modern Homo sapiens fragment. Some researchers have described the original postcranial fragments of Omo I as anatomically Omo Kibish modern but have noted that a variety of aspects of the specimen’s morphology depart -
Skeletal System Fact Sheet
Skeletal system fact sheet • At birth the human skeleton is made up of around 300 bones. By adulthood, some bones have fused together to end up with 206 bones. • Human bones grow continually from birth till our mid 20's. Our skeleton's bone mass is at its maximum density around the age of 30. • If broken our bones will re-grow and repair themselves. Often doctors will place a cast on splint to make sure these bones repair straight and true. • The axial skeleton part of the human skeleton has 80 bones. It includes the vertebral column, the rib cage and the skull and helps us maintain our upright posture, by spreading the weight in the head, and upper areas down to the lower areas near the hips. • The appendicular skeletal section of our skeleton has 126 bones. It includes the pectoral (shoulder) girdles, the pelvic girdle and the bones of the lower and upper limbs. Its function is for movement of the body and to protect some organs. • The human skeletal system has six major functions including the production of blood cells, for support, for movement, for protection, for storage of ions and endocrine regulation. • The longest bone in the human body is the thigh bone called the femur. • The smallest bone found in the human body is located in the middle ear. The staples (or stirrup) bone is only 2.8 millimetres (0.11 inches) long. • Like our skin, the human body's bones are also constantly worn down and re-made, to the point where every 7 years we essentially have a new bone. -
Human Anatomy and Physiology
LECTURE NOTES For Nursing Students Human Anatomy and Physiology Nega Assefa Alemaya University Yosief Tsige Jimma University In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education 2003 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2003 by Nega Assefa and Yosief Tsige All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty in a health care field. Human Anatomy and Physiology Preface There is a shortage in Ethiopia of teaching / learning material in the area of anatomy and physicalogy for nurses. The Carter Center EPHTI appreciating the problem and promoted the development of this lecture note that could help both the teachers and students.