Low Power Wireless Solutions for Healthcare Applications FTF-HCR-F0196

David Niewolny | Healthcare Segment Manager

A P R . 2 0 1 4

External Use Agenda

Topics: • Telehealth Ecosystems • IoT Architectures: Hub-Centric vs Cellular Direct • Most Optimum Wireless Standards • Example • Q & A David Niewolny Healthcare Segment Manager Freescale Semiconductor, Inc. Microcontroller Solutions Group United States, Austin TX We See a Healthier, Safer Population

TM External Use 1 Medical / Healthcare Device Architecture

Flash/ Communications EEPROM Interfaces

BT/LE Signal Conditioning LCD Driver Sensors ADC Wifi

Actuators DAC Zigbee

GSM / RTC Vref MCU/MPU Energy CDMA Harvesting Power Audio Codec & Ethernet Mgmt. Amp / USB

Touch Freescale Sensors Offer

TM External Use 2 Precision Analog Improves Accuracy

• The challenge: Increase device accuracy without increasing cost. − The FDA is requiring higher accuracy on most medical devices and changes to healthcare provide significant cost pressure

• The solution: Integrated precision analog. − Integrating precise analog components such as Op Amps, Tri Amps, high resolution ADC, and DACs

• Ideal solution – Platforms w/ flexible analog − Freescale offers customers fully integrated analog solutions that are pin compatible with solutions that have key analog peripherals needed to connect to a custom analog ASIC

TM External Use 3 3 Low Power Operation Extends Battery Life

• The challenge: Make the hardware as maintenance free as possible − Requiring a patient to replace batteries dramatically reduces the effectiveness of the medical device • The solution: Low power technologies − Use ultra low power microprocessors as the “brain” of the device with wireless technologies designed for low power networks − Make use of various sleep modes through efficient software design • Ultra Low Power Microcontrollers − 210uA/MHz run current (MCU) − Stop Mode operation <50nA (MCU) − RTC operation in <600nA (MCU) − LCD Operation <500nA (MCU) − 4us wake up time (MCU) • Ultra Low Power Microprocessors − 1600+ MIPS at <1W (MPU) • Ideal solution – eliminate batteries − Freescale is working to make this a reality with ultra low power converters

TM External Use 4 GUI Improves Device Usability

• The challenge: Make adding a GUI, easy low cost and easy to implement − Adding a GUI to a medical device has many advantages for patients like making operation easier, more fun, while delivering more information

• The solution: Integration and Software − Use microprocessors as the “brain” of the device with integrated LCD controllers or LCD enabled peripherals − Use LCD segment drivers, LCD graphics libraries, and GUI builders

• Ideal solution – Platform with Flexibility − Freescale has a wide variety of microcontrollers and microprocessors that have integrated LCD or LCD enabled peripherals

TM External Use 5 Interoperability and Communication Standards

• The challenge: Crossing the chasm − Adding communications functionality to medical devices that will “play nice” with other medical devices

• The solution: Continua Health Alliance − Creating guidelines for wireless and wired data transport between monitoring devices and healthcare providers − Guidelines are applicable to familiar, basic devices and more sophisticated devices

• Continua and IEEE certified software stacks − Ready to launch USB PHDC Software stack − Ease of use reduces time to market

• Wireless solutions that have climbed the S-curve including ZigBee and 802.15.4

TM External Use 6 It’s a Connected World Fostering Quality of Life

Interaction/Context Personal Gateway Internet Services

Motion Vital Monitoring Reaction Emotion Personal Posture Biometrics Fitness Tracker

Technique Trajectory low energy WLAN Impact Coaching Velocity Devices Power + objects Cellular Feedback data Weight-loss Entertainment Manager

Elderly Monitoring Location Altitude Temperature Ambient Virtual Humidity Sports Light Sound

TM External Use 7 Today’s Wireless Landscape: Interoperability Nightmare

Low data rate WAN (>1000) Wi-Max City & Nation TV Wide White Space M2M STDs, Cellular e.g. (HSXPA, LTE. LTE+, etc.) Weightless KNX WLAN (100)

Local Area Proprietary Wi-Fi Wide Wireless 802.11 a,b,g,n, ac, ad Wavenis HART Sub-GHz 2.4GHz

Z- Range (m) Range WPAN (10) wave A ANT+ RF4CE N

T BTLE RFID WBAN (1) NFC ZigBee Bluetooth

0.01 1 10 100 Data Rate (Mbps)

TM External Use 8 Continua Health Alliance

• Continua Health Alliance − Non-profit, open industry coalition of healthcare and technology companies joining together in collaboration to improve the quality of personal healthcare − Over 240 member companies globally, from payers to providers to medical equipment, consumer electronics manufacturers to systems integrators to silicon vendors − Establishing guidelines for interoperable personal health solutions . Foster living independence . Empower individuals to be better connected to their own health . Opportunity for truly personalized health and wellness management • Freescale and Continua − Freescale Semiconductor is a Continua promoter member − Dr. Jose Fernandez and I represent Freescale within the Continua Health Alliance and help drive the technical guidelines for development and standards selection.

TM External Use 9 Healthcare Connectivity Interfaces & Standard Personal Device Aggregation Health Thermometer Manager Records

Pulse Oximeter

Pulse / Blood Pressure

Weight Scale

Glucose Meter

Cardio / Strength Wide Health EHR Independent Area Record Living Activity Low-Power Network Network Local Area Peak Flow (WAN) (HRN) Network Interface Interface PHR Medication (LAN) Adherence Interface Telehealth Physical Activity Service Personal Center Area Network Electrocardiogram (PAN) Interfaces Insulin Pump

TM External Use 10 Wireless Bands Available for Healthcare

• US FCC recognizes several bands for medical applications − License-only, geographically restricted (FCC Part 95) . 401 – 406 MHz, 608 - 614 MHz, 1395 – 1400 MHz, 1427 – 1432 MHz . Implantables, in-hospital therapeutic devices, wearable devices . 2360 – 2400 MHz band .. Quite band just below frequency of Wi-Fi, Bluetooth, ZigBee

• US FCC also provides many license free bands − General Industrial, Scientific and Medical (ISM) purposes . 902 – 928 MHz, 2400 – 2483.5 MHz, 5725 – 5875 MHz and others

• Standards-based approaches are targeting these bands and others

TM External Use 11 Choices in Wireless Technology

• Standards-based − Personal area, up to ten meters . BT 4.0 Bluetooth and Bluetooth Low Energy (expanding healthcare profiles) . IEEE 802.15.6 BAN Body Area Network . IEEE 802.15.4j MBAN Medical Body Area Network

− Local area, up to tens of meters . Wi-Fi / IEEE 802.11 . ZigBee / IEEE 802.15.4 (ZigBee healthcare profiles)

− Wide Area, up to many kilometers . Cellular: GSM, UMTS, CDMA . TV whitespace: vacated by analog TV (developing standard)

• Proprietary − Mostly <10m range: MICS, MEDRadio, and WMTS devices

TM External Use 12 Local and Wide Area Networks – LAN and WAN LAN WAN

• Wi-Fi: IEEE 802.11 • Cellular: GSM/UMTS and CDMA − Dominant in clinical care settings − Support voice and data communication − Clinical IT staff knows how to provision, − Excellent transport security configure and maintain − Purpose-built modems for embedded − Supports variety of data rates up to hundreds of connectivity MB/sec − Typically powered by a rechargeable source − High data security − Cellular networks migrating toward a more IP- based infrastructure, will increase ease of use • ZigBee: IEEE 802.15.4 − Designed for M2M sensor and control networks, co-exists with Wi-Fi • TV White Space spectrum − Battery efficient, devices can sleep for months − TV whitespace: currently unused TV but still available in milliseconds broadcast channels vacated by analog TV − Multi-hop mesh networks from just a few to − Between VHF and UHF bands hundreds of devices − Basestation to 1000’s of M2M end-nodes − Communication and asset tracking − Low cost, long range connectivity − Deployment in major hospitals − Lightweight protocol using TDMA − A new SiG exists, weightless, proposing proprietary open standard

TM External Use 13 Standards Based Personal Area Network - PAN

• Bluetooth “Classic”: • BAN: Body Area Network BT1.x, 2.x, 3.0, Smart Ready 4.0 IEEE 802.15.6 − Master to client networks − Designed for use in or around human body (headset to handset, etc) − Secure and can be very low power − Well suited for cellular handset-centric applications − One MAC, three different PHYs − Low latency, moderate data rates − Narrowband in 402-2484Mhz − UWB in 3494-9984MHz − Good for audio from low-rate voice to streaming music − Human Body Comm in 21Mhz − In billions of handsets all around the world − 2360-2400MHz band is quite, sitting just below Wi-Fi, Bluetooth, ZigBee band • Bluetooth Low Energy (BLE): Bluetooth Smart BT4.0 • MBAN: Medical Body Area Network − Master to client networks (sensing device to IEEE 802.15.4j handset) − Wearable, portable, fixed sensors. No − Optimized for sleepy sensor devices, Implantables improving battery life 10-20x over Bluetooth − Uses standard 802.15.4 (2006) MAC/PHY, classic. 1+ on year coin-cell flexible channel scheme − Low latency, low data rate while connected − Operation limited to in- and around- − Majority handsets/tablets shipping with BLE hospital/care facility for 2360 – 2390 MHz now. Majority software enabled in 2015 − Operation anywhere for 2390 – 2400 MHz − 2360-2400MHz band is quite, sitting just below Wi-Fi, Bluetooth, ZigBee band

TM External Use 14 Freescale Offerings

TM External Use 15 Kinetis Microcontrollers (Now & in the Future…)

World’s Broadest ARM Cortex-M Portfolio

Kinetis X Series High-performance ARM Availability Cortex-M4/Mx MCU families NOW! Kinetis K Series with advanced memory and feature integration for robust, Industry-first ARM Cortex-M4 networked industrial and Performance Availability MCU families from 50MHz / consumer systems. NOW! 32KB with low power, Availability FlexMemory, mixed-signal and NOW! Kinetis E Series Kinetis L Series broad connectivity, HMI & Robust, 5V ARM Cortex-M0+ Ultra-low power/cost ARM security features. & ARM Cortex-M4 MCU Cortex-M0+ MCU families families for use in high from 48MHz / 8KB with mixed- electrical noise environments. signal, connectivity & HMI Safety features for high- features in low pin-count reliability applications packages. General Purpose Availability NOW! Kinetis V Series Segment Focused Availability High efficiency, high speed NOW! Kinetis M Series peripherals ARM Cortex-M0+ Kinetis W Series High accuracy metrology ARM & Cortex-M4 MCU families for Integrated wireless Cortex-M0+ MCU families for use in motor control & power connectivity ARM Cortex-M4 single chip smart meter conversion. and M0+ MCU families with Coming implementations. Q1 ‘14 class-leading sub-1 GHz and (samples 2.4 GHz RF transceivers now) Integration Leading Performance - Low Power - Scalability - Industrial-grade reliability & temp

Freescale Bundled IDE, RTOS & Middleware - Rapid prototyping Platform - Broad ARM Ecosystem Support

TM External Use 16 Kinetis Enables the Internet of Things

Smart Smart • Broad range of compatible Health Lighting ultra-low power and high- Smart performance MCUs Grid Gaming Smart M2M • Embedded memory and Gaming Cars peripheral sets aligned to a Building Point of Sale variety of applications Automation Smart Home Smart Energy Appliance • Miniaturization & advances Homes Air Quality in packaging technologies Control Wearables • Comprehensive hardware Smart Pedestrian Supply Chain Smart and software development Parking Navigation tools Automation Tags

Customer Applications Kinetis SDK MQX RTOS Reference Designs Application Notes Software Sensing Embedded Processing Connectivity

Kinetis L - Hub Kinetis K – High Performance Kinetis W – BLE, Kinetis K - Fusion Kinetis L – Low Power Zigbee, <1GHz Kinetis V – Power Conversion & Motor Control Kinetis E – 5V Robust TM External Use 17 Kinetis M – Metrology Technology

Connectivity Strategy

Wideband Technologies Narrowband Technologies (More Complex) (Less Complex)

• 802.11aPartner • BluetoothDevelop Low EnergyInternally (BLE) • 802.11b • 802.15.4 • 802.11g • ZigBee RF4CE• KW01 • 802.11n • ZigBee Pro• KW20 • WiFi Direct • ZigBee IP • HomePlug • Sub-GHz• KW40 • HomePlug Green PHY • Wireless• MKW60-Bus • G3-PLC • PRIME-PLC • P1901.2

TM External Use 18 Narrowband Connectivity Strategy

• Common Technology with MCU SoC RF

− 90nm TFS RF Low Tier Transceiver − Discrete, SIP & SoC Only • Multi-Mode Radio − ZigBee, BLE, Sub GHz ... System-In-Package SiP − One die, many protocols SiP SiP MCU MCU MCU • Ease of Use RF RF RF − MQX on Cortex M0+ / M4 − Scalable across MCU portfolio • Leadership Performance

− High RF performance SoC SoC

− Low power RF RF − Small die size High Volume SoC

TM External Use 19 BLE Options Monolithic SoC MCU + BLE Radio MCU + BLE SiP / RCP

Memories Memories Memories Memories RF + RF RF or CPU CPU RF IO CPU IO CPU IO CPU IO Mem

• Single chip • Most Flexibility • Single chip • Single chip solution solution solution • Limited on chip • Lowest cost memory (some • More MCU options • More MCU options offering consumed by easily explored easily explored BLE stack) • Smallest footprint • Optimized footprint • Dedicated core • Lowest flexibility • Radio steals and memory for • More expensive cycles from CPU, radio (CPU • Limited on chip than monolithic memory (some limiting system SoC performance and consumed by BLE performance memory not • Radio steals cycles affected) stack) • Large footprint from CPU, limiting • Optimized footprint • Radio steals system cycles from CPU, performance • Most expensive limiting system option today performance

TM External Use 20 System In Package (SiP)

− Example: MCU die + Sub-GHz RF radio die, in production today

side-by-side die position Radio Die

MCU Die

8x8mm LGA56 package

TM External Use 21 Kinetis KW3x-BLESiP1 MCU

Core System Memories BLE Radio

• CPU ARM CortexTM-M4 Internal and Program Flash BLE 4.0 radio 50 MHz External Watchdogs (Up to 512 KB) − 50 MHz Cortex M4 CPU core DMA − Up to 512 KB Flash & up to 64KB SRAM DSP SRAM FlexMemory Option Low Leakage Wake- − Optional: 64 KB FlexNVM & 4 KB FlexRAM 64 KB FlexNVM Up Unit Debug Interfaces 4 KB FlexRAM − Typical current: 250 uA/Mhz run, 1.7uA RTC DC-DC Converter standby Interrupt Controller Analog SRAM 32 MHz Osc • Radio Transceiver 16-bit ADC (Up to 64 KB) − BT 4.0 compliant SPI Interface Communications High Speed − -93 dBm Rx sensitivity and 0dBm Tx output Comparator with Timers power I2C 6-bit DAC Flex Timer Clocks − Peak typical current : <5mA Tx and <5mA Rx SPI Security Programmable Phase-Locked Loop − 16MHz XTAL Delay Block Cyclic Redundancy − UART (ISO 7816) DC-DC Boost / Buck Check (CRC) Frequency Locked − Self contained – radio software stacks included Periodic Interrupt Loop Timers USB On-The-Go (H) Tamper Detect • Security Low / High Cryptography Low Power Timer Frequency Osc. − Active and passive tamper detection with RTC USB Charger Detect Authentication Unit timestamp Random Number Independent Real Internal Reference USB Voltage Regulator − Crypto engine: DES, 3DES, AES 128-256, SHA- Generator Time Clock Clocks 1, SHA-256, MD5, RNG • Software Side-by-side Die Position − BLE Stack & Profiles Radio Die − MQX RTOS

• System MCU Die − UART, SPI, I2C, optional USB 2.0 FS/LS H/D/OTG − 16-bit ADC − Operating range: 1.8 V to 3.6 V, -40C to +105C 8x8mm LGA56 package

TM External Use 25 Kinetis W: BLE “Plus” Single chip MCU + BLE solutions for real applications

• Lots of integrated memory

Communication • High-performance Cortex-M4 Control • HMI support Display

Kinetis W • High precision on-chip analog Sensors

Input/Output • Abundant IO

• Unparalleled hardware & software scalability

TM External Use 26

Freescale i.MX 6 – Silex SDCAN Partnership

• 802.11a/b/g/n WLAN SDIO card based on Qualcomm Atheros AR6003 technology • Wi-Fi driver pre-integrated with various i.MX 6 development systems • Low power design ideal for portable battery operated device SPECIFICATIONS: applications Product Name SX-SDCAN-2830

• Family of “production ready” Chipset Qualcomm Atheros AR6233 hardware options available Wireless IEEE 802.11a/b/g/n

Host Interface SDIO v2.0 More information at www.silexamerica/freescale Operating Voltage 3.30VDC +/- 5% Operating Temperature -10 to + 70 degrees C FCC/IC (US/Canada) Regulatory Approvals R&TTE (EU), TELEC (Japan)

Silex Technology Solution Partner TM (US/Europe/Japan) External Use 27 Embedded Wireless Products

Intelligent Embedded Radio Modules Certified SDIO Radio Modules and Cards

SX-SDMAN SX-SDMGN SX-SDCAN 802.11a/b/g/n+BT 802.11b/g/n 802.11a/b/g/n+BT SX-580/SX-570 SMT or Connector Connector SDIO Card IEEE 802.11a/b/g/n Module Module Intelligent Communication Module

SDIO Radio SIP (System in Package) Mini-PCI and Mini-PCI Express

SX-SDPAN SX-SDPBN 802.11a/b/g/n+BT 802.11b/g/n SX-PCEAN SX-10WAN 802.11a/b/g/n 802.11a/b/g/n Mini PCI-Express Mini-PCI

Silex Technology is a Qualcomm Atheros Authorized Design Center (ADC) partner, providing various levels of wireless technology implementation support for the popular Atheros chipsets.

TM External Use 28 RCP With Integrated Antenna

Zigbee

WiFi

WiFi / BT 4.0

Traditional PCB Module RCP Module Size: 13x26x2 mm3 Size: 8x8x1 mm3 Modem only 121 MAP-BGA, 0.65mm pitch Modem + Full Featured Kinetis MCU Kinetis Tools & Enablement

TM External Use 29 Development Tools

TM External Use 30 Hardware Platforms

• Tower − KW2x − TWR-RF-MRB

• FRDM − KW4x

Others: USB Stick • MRB Antenna Diversity Board Reference Design − KW0x

Should all future general hardware enablement be on FRDM?

TM External Use 31 Connectivity Software Overview

Profiles and Apps

FSCI Component Framework Interface Interface Interface

FSCI API Component API Framework API FSCI Connectivity Freescale Connectivity Framework

Freescale Serial Components Task Mgr, Serial Mgr, Message Mgr, Task Mgr, Communication NVM Mgr, System Reset, System Panic Interface BLE Data Logger CMSIS - RTOS IPv4/v6 Stack Device Drivers ZigBeePRO MQX Lite (PEx or KSDK) ZigBeeIP

802.11 b/g/n MCU Hardware Peripherals

802.15.4g

TM External Use 32 Reference Designs

TM External Use 34 Gateway Deployment Example – “One Box”

• Physician Tablet with Medical • Social Networking User Interface (i.MX6) • Monitoring Center • Loved Ones Ethernet

Reference Platform Gateway (i.MX28) HOME AUTOMATION OneBox Expanding the Reference Platform Smart Plugs Smart Appliances Safety/Security TELE-HEALTH Lighting Control Local Display

868MHz RF Bluetooth HDP Bluetooth USB Healthcare Low Energy PHDC Bluetooth SPP Panic Alarm Weight Scale (MC12311) Thermometer Blood Pressure Wired connection Nonin Pulse Ox Monitors Wireless connection (MC9S08GP32) Blood Glucose Meter Medical monitoring WWW connection

TM External Use 35 “OneBox” …. Have it Your Way… Home/Patient/Clinical

Configurable “OneBox”

ZigBee Ethernet Radio Sub GHz 802.11n Processor Radio Optional WiFi with 802.15.4j Plug-In Operating Radio Modules System USB HS 802.15.6 Radio Bluetooth4.0 (includes BT Low Other Energy)

TM External Use 36

WaRPboard.org

TBD

ET017QC1 EPD DISPLAY EPD BATTERY SINGLE DISPLAY LCD CELL LIPO Main Board PCB size: (500mAh) TOUCH INTERFACE 38 mm x 14 mm Freescale Wearable (1.49”x 0.55”) LCD POWER MIPI EPD Reference Platform Solomon Systech CONNECTOR CONNECTOR Main Board

MANAGEMENT SSD2805C

Maxim MAX77696 3-axis ACCELERO

RGB BOARD BOARD

3-axis MAGNETO

SPI -

FXOS8700CQ to

i.MX 6SL - MICRO USB USB ARM ® Cortex™-A9

Apps Processor CONNECTOR MEMORY BT/BTLE W-LAN / DDR2 Running Android UART LPDDR2 + eMMC BLUETOOTH 4.0 BOARD Samsung MCP WIFI SDIO SDIO KMN5W000ZM-B207 Murata LBEH17YSHC

Freescale Wearable Reference Platform HUB SENSOR Daughter Board

MCU – Kinetis KL16

ARM Cortex™ M0+

BOARD BOARD

to to

- Daughter Board PCB size: 42 mm x 42 mm MOTION SENSING CONNECTOR PEDOMETER WIRELESS (1.65” x 1.65”) CHARGING BOARD MMA9553 BUTTON 1 BUTTON 2

Freescale TM External Use 37 Technology

WaRP with Medical Daughter Board

TBD

BATTERY SINGLE ET017QC1 WaRPboard.org EPD DISPLAY EPD CELL LIPO DISPLAY LCD (500mAh) TOUCH INTERFACE

LCD EPD Freescale Wearable Main Board PCB target size: MIPI Reference Platform POWER CONNECTOR 8 mm x 42 mm Solomon Systech CONNECTOR Main Board

MANAGEMENT SSD2805C

Maxim MAX77696 3-axis ACCELERO

RGB BOARD BOARD

3-axis MAGNETO

SPI -

FXOS8700CQ to

MICRO USB USB i.MX6SL CONNECTOR MEMORY BT/BTLE W-LAN / DDR2 UART LPDDR2 + eMMC BLUETOOTH 4.0 BOARD Daughter Board PCB target Samsung MCP WIFI SDIO SDIO Murata LBEH17YSHC size: 80 mm x 42 mm KMN5W000ZM-B207

Freescale Wearable Reference Platform Daughter / Contact Board 2 CONTACT SENSOR HUB SENSOR 2x2:1 ECG / HR / EMG FILTERING MUX MCU

Plessey EPIC PS25251 MK50DX128VMC7 (TBC)

BOARD BOARD

to to

2 CONTACT SENSOR MOTION SENSING CONNECTOR FILTERING PEDOMETER WIRELESS

ECG / HR / EMG BOARD CHARGING Plessey EPIC PS25251 MMA9553 BUTTON 1 BUTTON 2

TM External Use 38 Application Examples

• Time, chrono, lap time, alarms WaRPboard.org • Smart music player with audio streaming via BT to headset • Photo and video player • Wi-Fi connectivity • Compass display • Free fall detection • Pedometer / activity monitor main board − Step counter (pedometer) battery − Motion detection (walking, running) − Distance traveled button − Calories • ECG & Heart Rate • Wake up on motion daughter board • Charging over USB • Wireless charging

TM External Use 39 Summary

• Healthcare costs higher than ever • Unprecedented opportunity for integrating wireless into healthcare/medical devices • Many wireless standards, but only a handful are best for healthcare/medical applications • Freescale is a leader in enabling IoT applications via secure low power wireless

More info at www.freescale.com/healthcare

Connect with us Freescale Tweeting? Medical by Design Blog on Facebook Please follow us freescale.com/medical facebook.com/freescale @freescale

TM External Use 40 TM