Open Access Case Report DOI: 10.7759/cureus.2876 Painful Bladder Syndrome/Interstitial Cystitis Successful Treatment with Montelukast: A Case Report and Literature Review Muhammad Wajih Ullah 1 , Sunita Lakhani 2 , Sunder Sham 3 , Afshan Rehman 4 , Wardah Siddiq 5 , Tariq Siddiqui 6 1. Cardiology, Mayo Clinic, Rochester, USA 2. Internal Medicine, Liaquat University of Medical and Health Sciences Hospital, Jamshoro, PAK 3. Internal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK 4. Internal Medicine, Baylor Saint Luke's Medical Center, Houston, USA 5. Internal Medicine, Beth Israel Deaconess Medical Center/Harvard Medical College, Boston, USA 6. Internal Medicine, Maharashtra Institute of Medical Education & Research, Talegaon, IND Corresponding author: Muhammad Wajih Ullah,
[email protected] Abstract Painful bladder syndrome/interstitial cystitis (PBS/IC) is a chronic condition characterized by pelvic pain, urinary frequency, and urgency for more than six months in the absence of urinary tract infections. The etiology of PBS/IC is still an enigma. PBS/IC is challenging for doctors to diagnose because its symptoms overlap with other diseases such as urinary tract infection, overactive bladder, or endometriosis. Hence, it is diagnosed after excluding those diseases. The prognosis of PBS/IC may vary because of multiple treatment options. In this study, we are documenting a 26-year-old female patient who was successfully treated with montelukast after diagnosed with PBS/IC. Categories: Internal Medicine, Urology, Pulmonology Keywords: bladder pain syndrome, montelukast, asthma Introduction Painful bladder syndrome/interstitial cystitis (PBS/IC) is a disease of unknown etiology. The male-to-female ratio is 1:9 in the US population survey [1].