7: Biological Sciences*

Total Page:16

File Type:pdf, Size:1020Kb

7: Biological Sciences* Subject Index to Volume 1'7: Biological Sciences* January-Dece:nber 1980 Introdul ction The terms of the Subject Index for Volu me 77, January-December 1980, of the PROCEEDINGS OF THE NATIONAL ACA] )EMY OF SCIENCES USA (Biological Sciences) were chosen from titles, key terr ns, and abstracts of articles. The index terms are alphabetized by computer; nui abers, conformational prefixes, Greek letters, hyphens, and spaces between words aredisregarded in alphabetization. After each index term is printed the title of the Erticle (or a suitable modification of the title) and the appropriate page number. Tit [es are listed in alphabetical order under the index terms. Corrections to papers in which errors occurred are indexed under the term "Correction"as well as under the index term s selected for the paper itself. Organisms are indexed by their scientific names whe] i scientific names were provided in the papers; suitable cross-references are provi ded. Because the PROCEEDINGSurges autho rs to follow the tentative rules and rec- ommendations of the nomenclature comrmissions (e.g., for biochemistry, those proposed by the International Union of E iochemistry), an effort has been made to construct an index that conforms with t] lis policy. However, correction of errors in nomenclature was not attempted and t he index should not be looked upon as a reference for correct or recommended us. tge. In addition, some exceptions to the recommendations of the commissions were necessary. Index terms themselves are usually not abbreviated even if specific re( 'ommendations have been made by the commissions; and in some instances, wordsI within an index term were rearranged. (Thus, tRNA is indexed as "Ribonucleic acid, transfer.?') In general, analogs of compounds are indexed as the parent com] )ound. (Thus, dimethylbenzanthracene is indexed as "Benzanthracene, dimethyl-.' ') The "Recommended Name" from the 1978 recommendations of the Nomenclatur e Committee of the International Union of Biochemistry on the Nomenclature ar d Classification of Enzymes [Enzyme Nomenclature (1978), Academic Press, I 4ew York] has been used for enzymes whenever Enzyme Commission (EC) num bers were published in the papers. EC numbers are listed as part'of the entry on ly if the EC number was printed in the paper. [Thus, some enzymes have two entri es, e.g., "Adenosinetriphosphatase"' and "Adenosinetriphosphatase (EC 3.6.1.3)."] * Subject index for Physical Sciences begins on p. 7623. 754: Downloaded by guest on September 29, 2021 7542 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 77 (1980) Abetalipoproteinemia Analysisof mechanismof fast axonaltransport by intracellularinjection see also Hyperapobetalipoproteinemia of potentiallyinhibitory macromolecules: Possible role of actin Inabilityof serumfrom abetalipoproteinemicsubjects to stimulate filaments,7448 proliferationof humansmooth muscle cells and dermalfibroblasts in Appearanceof cytoskeletalcomponents on the surfaceof leukemiacells vitro, 1511 and of lymphocytes transformed by mitogens and Epstein-Barr virus, Abscisicacid 4979 Abscisicacid content of oat leaves:Changes during senescence, 2050 ATP-drivensteady-state exchange of monomericand filamentousactin Acetate kinase (EC 2.7.2.1) from Dictyostelium discoideum, 4610 Acetate kinase:A triple-displacementenzyme, 2626 Bioenergetic aspects and polymer length distribution in steady-state Acetobacterxylinum head-to-tail polymerization of actin or microtubules, 4803 Cellulosebiogenesis: Polymerization and crystallizationare coupled Calciumcontrol of intestinalmicrovillus cytoskeleton: Implications for processesin Acetobacterxylinum, 6678 regulationof microfilamentorganizations, 6458 Acetone Cooperativebinding of myosinsubfragment 1 to Acetonemetabolism in mice:Increased activity in mice heterozygousfor actin-troponin-tropomyosincomplex, 2616 obesity genes, 290 Cooperativebinding of subfragment1 to regulatedactin: Kinetic studies, N-Acetoxy-2-acetylaminofluorene 7209 Chemicalcarcinogen-modified DNA recognizedby a DNA-binding Cooperativeequilibrium binding of myosin subfragment1 to protein,3201 actin-troponin-tropomyosincomplex: Theoretical model, 3186 Chemicalcarcinogen-modified DNA recognizedby a DNA-binding CytoskeletalF-actin patternsquantitated with fluorescein protein (correction),7510 isothiocyanate-phalloidin in normal and transformed cells, 6624 Conformationof poly(dG-dC).poly(dG-dC)modified by carcinogens Fluorescence staining of actin cytoskeleton in living cells with N-acetoxy-N-acetyl-2-aminofluoreneand 7-nitrobenz-2-oxa-1,3-diazole-phallacidin,980 N-hydroxy-N-2-aminofluorene,4597 Fluorescencestaining of actin cytoskeletonin living cells with Acetylcholine 7-nitrobenz-2-oxa-1,3-diazole-phallacidin(correction), 3747 see also Receptor,acetylcholine Immunologicaldifferences between actins from cardiacmuscle, skeletal Acetylcholine:Specific stimulated uptake by Torpedoelectric organ muscle, and brain, 2069 synapticvesicles, 6234 Recombinantplasmids'constructed containing rat muscle actin and Early nerve-musclesynapses in vitro releasetransmitter over myosinlight chain DNA sequences,960 postsynapticmembrane having low acetylcholinesensitivity, 644 Reversible translocation of cytoplasmic actin into the nucleus caused by Kinetic modelssuggest bimolecularreaction steps in axonal Na+-channel .dimethyl sulfoxide, 5268 gating,6582 a-Actinin Leptinotarsin:A presynapticneurotoxin that stimulatesrelease of Cytoskeletalproteins vinculin and a-actinin:Altered distributions in acetycholine,1219 culturedfibroblasts transformed by Rous sarcomavirus, 6687 Quantalrelease of acetylcholineexamined by currentfluctuation analysis Active avoidance at identifiedneuro-neuronal synapse of Aplysia, 1661 Enkephalinand fear-motivatedbehavior, 3729 Single channelcurrents from excised patches of muscle membrane,6930 Acyclovir Acetylcholinesterase(EC 3.1.1.7) Acyclovir inhibition of Epstein-Barr virus replication, 5163 Acetylcholinesterase:Photodestruction, 1980 Adaptation Clumpingof acetylcholinesteraseactivity in developingstriatum of Spatial frequencyspecific interactionof dot patternsand gratings,662 humanfetus and young infant, 1214 Adenine,isopentenyl- Collagen-tailedand hydrophobiccomponents of acetylcholinesterasein Isopentenyladenineas a mediatorof mevalonate-regulatedDNA Torpedomarmorata electric organ, 4464 replication,5842 Specific photoaffinitylabeling induced by energytransfer: Application to Adenosine irreversibleinhibition of acetylcholinesterase,6439' see also Receptor, adenosine Vasoactiveintestinal polypeptidein cholinergicneurons of exocrine Adenosine,2-chloro- glands:Functional significance of coexistingtransmitters for Putative centralpurinergic receptors: Biochemical characterization by vasodilationand secretion,1651 using 2-chloro[3H]adenosine,a stable analogof adenosine,6892 Acetyl-CoAcarboxylase (EC 6.4.1.2) Adenosine3',5'-cyclic monophosphate Fatty acid-requiringmutant of Saccharomycescerevisiae defective in see also Adenylate cyclase; Receptor, adenosine 3',5'-cyclic acetyl-CoAcarboxylase, 1814 monophosphate Regulationof acetyl-CoAcarboxylase: Properties of CoA activationof Actin nascent chains are substrates for cyclic AMP-dependent acetyl-CoAcarboxylase, 3351 phosphorylation in vivo, 910 N-Acetylglucosamine Adenylate cyclase and immunologic release of mediators from rat mast Phosphorylatedoligosaccharides in lysosomalenzymes: Identification of cells: Agonist and antagonist effects of purine- and ribose-modified a-N-acetylglucosamine(l)phospho(6)mannosediester groups,7074 adenosine analogs, 6800 N-Acetylglucosamine-6-sulfatesulfatase A "mute" catalytic subunit of cyclic AMP-dependent protein kinase Sanfilippodisease type D: Deficiencyof N-acetylglucosamine-6-sulfate from rat muscle and its mode of activation, 2492 sulfataserequired for heparansulfate degradation,6822 Calcium and microtubule dependence for increased ornithine N-Acetylmuramyl-L-alany--D-isoglutamine decarboxylase activity stimulated by f-adrenergic agonists, dibutyryl Antiviralresponse elicited by a completelysynthetic antigen with cyclic AMP, or serum in a rat astrocytoma cell line, 995 built-in adjuvanticity,67,69 Calcium current modulation underlying presynaptic facilitation and Geneticallycontrolled formation of antibodyto a synthetic antigen behavioral sensitization in Aplysia: Mechanism, 6912 [poly(LTyr,LGlu)-poly(DLAla)--poly(LLys)] covalently bound to a Calcium-dependent hormonal regulation of amino acid transport and synthetic adjuvant(N-acetylmuramyl-L-alanyl-D-isoglutamine), 4933 cyclic AMP accumulation in rat hepatocyte monolayer cultures, 5953 Acetylserotoninmethyltransferase (EC 2.1.1.4) Catalyticsubunit of cyclic AMP-dependentprotein kinase: Pteridinesas nonretinalregulators of light-dependentmelatonin Microinjection enhances calcium action potentials of bag cell neurons biosynthesis,2415 in cell culture,7487 N-Acetyltransferase Changein rate of transcriptionof a eukaryoticgene in responseto cyclic see Arylamineacetyltransferase AMP, 7171 Acholeplasmalaidlawii Cyclic AMP accumulation in cultured brain cells: Regulation by secretin, Membranelipid physicalstate and modulationof Na+,Mg2+-ATPase vasoactive intestinal peptide, and somatostatin, 6907 activity in Acholeplasmalaidlawii B, 1255 Cyclic AMP: A role in expression of developmentally regulated genes in Acid-basetitration Dictyostelium discoideum, 1044 Net proton-hydroxylpermeability of largeunilamellar liposomes Cyclic AMP as a negative regulator of hormonally induced lactogenesis measuredby an acid-basetitration
Recommended publications
  • A Phase I Trial of Tamoxifen with Ribociclib (LEE011) in Adult Patients with Advanced ER+ (HER2 Negative) Breast Cancer
    The TEEL Study: A Phase I Trial of Tamoxifen with Ribociclib (LEE011) in Adult Patients with Advanced ER+ (HER2 Negative) Breast Cancer NCT02586675 Version 12.0 September 14, 2016 TEEL Protocol- Tamoxifen +Ribociclib Page 1 TITLE PAGE The TEEL Study: A Phase I trial of Tamoxifen with Ribociclib (LEE011) in adult patients with advanced ER+ (HER2 negative) breast cancer. Protocol: MCC 18332 Chesapeake IRB Pro00015228 Principal Investigator: Co-Investigators: Statistician: Experimental Therapeutics Program H. Lee Moffitt Cancer Center 12902 Magnolia Drive Tampa, FL 33612 & Comprehensive Breast Program Moffitt McKinley Outpatient Center 10920 N. McKinley Dr. Tampa, FL 33612 Study Site Contact: Protocol Version 12 Date: September 14, 2016 TEEL Protocol- Tamoxifen +Ribociclib Page 2 TITLE PAGE .............................................................................................................................................. 1 SYNOPSIS ................................................................................................................................................... 5 Patient Population ................................................................................................................................. 5 Type of Study ......................................................................................................................................... 5 Prior Therapy......................................................................................................................................... 5
    [Show full text]
  • Immunoglobulin G Is a Platelet Alpha Granule-Secreted Protein
    Immunoglobulin G is a platelet alpha granule-secreted protein. J N George, … , L K Knieriem, D F Bainton J Clin Invest. 1985;76(5):2020-2025. https://doi.org/10.1172/JCI112203. Research Article It has been known for 27 yr that blood platelets contain IgG, yet its subcellular location and significance have never been clearly determined. In these studies, the location of IgG within human platelets was investigated by immunocytochemical techniques and by the response of platelet IgG to agents that cause platelet secretion. Using frozen thin-sections of platelets and an immunogold probe, IgG was located within the alpha-granules. Thrombin stimulation caused parallel secretion of platelet IgG and two known alpha-granule proteins, platelet factor 4 and beta-thromboglobulin, beginning at 0.02 U/ml and reaching 100% at 0.5 U/ml. Thrombin-induced secretion of all three proteins was inhibited by prostaglandin E1 and dibutyryl-cyclic AMP. Calcium ionophore A23187 also caused parallel secretion of all three proteins, whereas ADP caused virtually no secretion of any of the three. From these data and a review of the literature, we hypothesize that plasma IgG is taken up by megakaryocytes and delivered to the alpha-granules, where it is stored for later secretion by mature platelets. Find the latest version: https://jci.me/112203/pdf Rapid Publication Immunoglobulin G Is a Platelet Alpha Granule-secreted Protein James N. George, Sherry Saucerman, Shirley P. Levine, and Linda K. Knieriem Division ofHematology, Department ofMedicine, University of Texas Health Science Center, and Audie L. Murphy Veterans Hospital, San Antonio, Texas 78284 Dorothy F.
    [Show full text]
  • Katalog 2015 Cover Paul Lin *Hinweis Förderung.Indd
    Product List 2015 WE LIVE SERVICE Certificates quartett owns two productions sites that are certified according to EN ISO 9001:2008 Quality management systems - Requirements EN ISO 13485:2012 + AC:2012 Medical devices - Quality management systems - Requirements for regulatory purposes GMP Conformity Our quality management guarantees products of highest quality! 2 Foreword to the quartett product list 2015 quartett Immunodiagnostika, Biotechnologie + Kosmetik Vertriebs GmbH welcomes you as one of our new business partners as well as all of our previous loyal clients. You are now member of quartett´s worldwide customers. First of all we would like to introduce ourselves to you. Founded as a family-run company in 1986, quartett ensures for more than a quarter of a century consistent quality of products. Service and support of our valued customers are our daily businesses. And we will continue! In the end 80´s quartett offered radioimmunoassay and enzyme immunoassay kits from different manufacturers in the USA. In the beginning 90´s the company changed its strategy from offering products for routine diagnostic to the increasing field of research and development. Setting up a production plant in 1997 and a second one in 2011 supported this decision. The company specialized its product profile in the field of manufacturing synthetic peptides for antibody production, peptides such as protease inhibitors, biochemical reagents and products for histology, cytology and immunohistology. All products are exclusively manufactured in Germany without outsourcing any production step. Nowadays, we expand into all other diagnostic and research fields and supply our customers in universities, government institutes, pharmaceutical and biotechnological companies, hospitals, and private doctor offices.
    [Show full text]
  • The Principles and Applications of Avidin-Based Nanoparticles in Drug Delivery and Diagnosis
    Journal of Controlled Release 245 (2017) 27–40 Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Review article The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis Akshay Jain, Kun Cheng ⁎ Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri Kansas City, Kansas City, MO 64108, United States article info abstract Article history: Avidin-biotin interaction is one of the strongest non-covalent interactions in the nature. Avidin and its analogues Received 7 October 2016 have therefore been extensively utilized as probes and affinity matrices for a wide variety of applications in bio- Accepted 7 November 2016 chemical assays, diagnosis, affinity purification, and drug delivery. Recently, there has been a growing interest in Available online 16 November 2016 exploring this non-covalent interaction in nanoscale drug delivery systems for pharmaceutical agents, including small molecules, proteins, vaccines, monoclonal antibodies, and nucleic acids. Particularly, the ease of fabrication Keywords: Nanotechnology without losing the chemical and biological properties of the coupled moieties makes the avidin-biotin system a Avidin versatile platform for nanotechnology. In addition, avidin-based nanoparticles have been investigated as Neutravidin diagnostic systems for various tumors and surface antigens. In this review, we will highlight the various Streptavidin fabrication principles and biomedical applications of avidin-based nanoparticles in drug delivery and diagnosis. Non-covalent interaction The structures and biochemical properties of avidin, biotin and their respective analogues will also be discussed. Drug delivery © 2016 Elsevier B.V. All rights reserved. Imaging Diagnosis Contents 1. Introduction............................................................... 27 2. Biochemicalinsightsofavidin,biotinandanalogues............................................
    [Show full text]
  • Recombinant Escheichia Coli-Catalyzed Production of Cytidine 5′-Triphosphate from Cytidine 5′-Monophosphate
    J. Ind. Eng. Chem., Vol. 12, No. 5, (2006) 757-761 Recombinant Escheichia coli-Catalyzed Production of Cytidine 5′-Triphosphate from Cytidine 5′-Monophosphate Sun-Gu Lee† and Byung-Gee Kim* Department of Chemical and Biochemical Engineering, Pusan National University, Busan 609-735, Korea *School of Chemical Engineering, and Institute of Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Korea Received April 24, 2006; Accepted May 22, 2006 Abstract: A recombinant Escherichia coli overexpressing CMP-kinase was constructed and employed as a whole cell biocatalyst for the conversion of cytidine 5′-monophosphate to cytidine 5′-triphosphate. In the whole cell biocatalysis, recombinant CMP kinase catalyzed the conversion of CMP to CDP, and endogenous acetate kinase of the E. coli was utilized for the ATP regeneration as well as for the conversion of CDP to CTP. A conversion yield of ca. 88 % CTP was obtained when starting with 20 mM CMP, 1 mM ATP, and 80 mM acetyl phosphate based on the initial CMP concentration. Endogenous pyruvate kinase and poly- phosphate kinase were inefficient in the process. The CTP production system was applied to the production of CMP-NeuAc by additionally introducing the CMP-NeuAc synthetase gene into the recombinant E. coli. Keywords: CMP-kinase, whole cell biocatalysis, ATP regeneration, cytidine 5′-monophosphate Introduction employing enzymes [4]. They applied various enzymatic 1) methods and chemical methods and concluded that the As glycosyltransferase-catalyzed synthetic techniques enzymatic method based on adenylate kinase/pyruvate are becoming recognized as powerful methods for the kinase provided the most convenient route to CTP. In the preparation of biologically important oligosaccharides, process, CTP was generated efficiently from an inexpen- the development of cost-efficient production methods for sive substrate, CMP.
    [Show full text]
  • Preventive Report Appendix
    Title Authors Published Journal Volume Issue Pages DOI Final Status Exclusion Reason Nasal sumatriptan is effective in treatment of migraine attacks in children: A Ahonen K.; Hamalainen ML.; Rantala H.; 2004 Neurology 62 6 883-7 10.1212/01.wnl.0000115105.05966.a7 Deemed irrelevant in initial screening Seasonal variation in migraine. Alstadhaug KB.; Salvesen R.; Bekkelund SI. Cephalalgia : an 2005 international journal 25 10 811-6 10.1111/j.1468-2982.2005.01018.x Deemed irrelevant in initial screening Flunarizine, a calcium channel blocker: a new prophylactic drug in migraine. Amery WK. 1983 Headache 23 2 70-4 10.1111/j.1526-4610.1983.hed2302070 Deemed irrelevant in initial screening Monoamine oxidase inhibitors in the control of migraine. Anthony M.; Lance JW. Proceedings of the 1970 Australian 7 45-7 Deemed irrelevant in initial screening Prostaglandins and prostaglandin receptor antagonism in migraine. Antonova M. 2013 Danish medical 60 5 B4635 Deemed irrelevant in initial screening Divalproex extended-release in adolescent migraine prophylaxis: results of a Apostol G.; Cady RK.; Laforet GA.; Robieson randomized, double-blind, placebo-controlled study. WZ.; Olson E.; Abi-Saab WM.; Saltarelli M. 2008 Headache 48 7 1012-25 10.1111/j.1526-4610.2008.01081.x Deemed irrelevant in initial screening Divalproex sodium extended-release for the prophylaxis of migraine headache in Apostol G.; Lewis DW.; Laforet GA.; adolescents: results of a stand-alone, long-term open-label safety study. Robieson WZ.; Fugate JM.; Abi-Saab WM.; 2009 Headache 49 1 45-53 10.1111/j.1526-4610.2008.01279.x Deemed irrelevant in initial screening Safety and tolerability of divalproex sodium extended-release in the prophylaxis of Apostol G.; Pakalnis A.; Laforet GA.; migraine headaches: results of an open-label extension trial in adolescents.
    [Show full text]
  • Découverte D'une Nouvelle Famille De Protéine Kinases Bactériennes
    Découverte d’une nouvelle famille de protéine kinases bactériennes : mécanismes de fonctionnement et rôle cellulaire de YdiB, un archétype chez Baccillus subtilis Hien-Anh Nguyen To cite this version: Hien-Anh Nguyen. Découverte d’une nouvelle famille de protéine kinases bactériennes : mécanismes de fonctionnement et rôle cellulaire de YdiB, un archétype chez Baccillus subtilis. Sciences agricoles. Université de Grenoble, 2012. Français. NNT : 2012GRENV017. tel-00721757 HAL Id: tel-00721757 https://tel.archives-ouvertes.fr/tel-00721757 Submitted on 30 Jul 2012 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. THÈSE Pour obtenir le grade de DOCTEUR DE L’UNIVERSITÉ DE GRENOBLE Spécialité : Chimie-Biologie Arrêté ministériel : 7 août 2006 Présentée par Hien-Anh NGUYEN Thèse dirigée par le Dr. Jean-Michel JAULT préparée au sein de l’Institut de Biologie Structurale J.-P. Ebel, et du CEA de Grenoble dans l'École Doctorale Chimie et Sciences du Vivant Découverte d’une nouvelle famille de protéines kinases bactériennes : Mécanisme de fonctionnement et rôle cellulaire de YdiB, un représentant chez B. subtilis Thèse soutenue publiquement le 23 mai 2012 devant le jury composé de : Mme. Patricia DOUBLET Rapporteur Prof.
    [Show full text]
  • ELISA Kit for Hemopexin (HPX)
    SEB986Ra 96 Tests Enzyme-linked Immunosorbent Assay Kit For Hemopexin (HPX) Organism Species: Rattus norvegicus (Rat) Instruction manual FOR IN VITRO AND RESEARCH USE ONLY NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES 11th Edition (Revised in July, 2013) [ INTENDED USE ] The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of hemopexin in rat serum, plasma and other biological fluids. [ REAGENTS AND MATERIALS PROVIDED ] Reagents Quantity Reagents Quantity Pre-coated, ready to use 96-well strip plate 1 Plate sealer for 96 wells 4 Standard 2 Standard Diluent 1×20mL Detection Reagent A 1×120μL Assay Diluent A 1×12mL Detection Reagent B 1×120μL Assay Diluent B 1×12mL TMB Substrate 1×9mL Stop Solution 1×6mL Wash Buffer (30 × concentrate) 1×20mL Instruction manual 1 [ MATERIALS REQUIRED BUT NOT SUPPLIED ] 1. Microplate reader with 450 ± 10nm filter. 2. Precision single or multi-channel pipettes and disposable tips. 3. Eppendorf Tubes for diluting samples. 4. Deionized or distilled water. 5. Absorbent paper for blotting the microtiter plate. 6. Container for Wash Solution [ STORAGE OF THE KITS ] 1. For unopened kit: All the reagents should be kept according to the labels on vials. The Standard, Detection Reagent A, Detection Reagent B and the 96-well strip plate should be stored at -20oC upon receipt while the others should be at 4 oC. 2. For opened kit: When the kit is opened, the remaining reagents still need to be stored according to the above storage condition. Besides, please return the unused wells to the foil pouch containing the desiccant pack, and reseal along entire edge of zip-seal.
    [Show full text]
  • Rnase I Manual
    Manual RNase I For Research Use Only. Not for use in diagnostic procedures. RNase I is part of the Epicentre™ product line, known for its unique genomics kits, enzymes, and reagents which offer high quality and reliable performance. Manual RNase I Contents 1. Introduction .......................................................................................................................................3 2. Product designations and kit components ....................................................................................3 3. Product specifications ......................................................................................................................3 4. Protocol for removing RNA from DNA preparations .....................................................................4 5. References .........................................................................................................................................4 6. Further support .................................................................................................................................4 Manual RNase I 1. Introduction RNase I preferentially degrades single-stranded RNA to individual nucleoside 3′ monophosphates by cleaving every phosphodiester bond.1 By comparison, other ribonucleases cleave only after specific residues (e.g., RNase A cleaves 3′ to pyrimidine residues). Thus, RNase I is useful for removing RNA from DNA preparations,2 detecting mismatches in RNA:RNA and RNA:DNA hybrids2,3 and analysing and quantifying RNA in ribonuclease
    [Show full text]
  • Title 16. Crimes and Offenses Chapter 13. Controlled Substances Article 1
    TITLE 16. CRIMES AND OFFENSES CHAPTER 13. CONTROLLED SUBSTANCES ARTICLE 1. GENERAL PROVISIONS § 16-13-1. Drug related objects (a) As used in this Code section, the term: (1) "Controlled substance" shall have the same meaning as defined in Article 2 of this chapter, relating to controlled substances. For the purposes of this Code section, the term "controlled substance" shall include marijuana as defined by paragraph (16) of Code Section 16-13-21. (2) "Dangerous drug" shall have the same meaning as defined in Article 3 of this chapter, relating to dangerous drugs. (3) "Drug related object" means any machine, instrument, tool, equipment, contrivance, or device which an average person would reasonably conclude is intended to be used for one or more of the following purposes: (A) To introduce into the human body any dangerous drug or controlled substance under circumstances in violation of the laws of this state; (B) To enhance the effect on the human body of any dangerous drug or controlled substance under circumstances in violation of the laws of this state; (C) To conceal any quantity of any dangerous drug or controlled substance under circumstances in violation of the laws of this state; or (D) To test the strength, effectiveness, or purity of any dangerous drug or controlled substance under circumstances in violation of the laws of this state. (4) "Knowingly" means having general knowledge that a machine, instrument, tool, item of equipment, contrivance, or device is a drug related object or having reasonable grounds to believe that any such object is or may, to an average person, appear to be a drug related object.
    [Show full text]
  • Supplementary Materials
    Supplementary Materials COMPARATIVE ANALYSIS OF THE TRANSCRIPTOME, PROTEOME AND miRNA PROFILE OF KUPFFER CELLS AND MONOCYTES Andrey Elchaninov1,3*, Anastasiya Lokhonina1,3, Maria Nikitina2, Polina Vishnyakova1,3, Andrey Makarov1, Irina Arutyunyan1, Anastasiya Poltavets1, Evgeniya Kananykhina2, Sergey Kovalchuk4, Evgeny Karpulevich5,6, Galina Bolshakova2, Gennady Sukhikh1, Timur Fatkhudinov2,3 1 Laboratory of Regenerative Medicine, National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation, Moscow, Russia 2 Laboratory of Growth and Development, Scientific Research Institute of Human Morphology, Moscow, Russia 3 Histology Department, Medical Institute, Peoples' Friendship University of Russia, Moscow, Russia 4 Laboratory of Bioinformatic methods for Combinatorial Chemistry and Biology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia 5 Information Systems Department, Ivannikov Institute for System Programming of the Russian Academy of Sciences, Moscow, Russia 6 Genome Engineering Laboratory, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia Figure S1. Flow cytometry analysis of unsorted blood sample. Representative forward, side scattering and histogram are shown. The proportions of negative cells were determined in relation to the isotype controls. The percentages of positive cells are indicated. The blue curve corresponds to the isotype control. Figure S2. Flow cytometry analysis of unsorted liver stromal cells. Representative forward, side scattering and histogram are shown. The proportions of negative cells were determined in relation to the isotype controls. The percentages of positive cells are indicated. The blue curve corresponds to the isotype control. Figure S3. MiRNAs expression analysis in monocytes and Kupffer cells. Full-length of heatmaps are presented.
    [Show full text]
  • Generate Metabolic Map Poster
    Authors: Pallavi Subhraveti Anamika Kothari Quang Ong Ron Caspi An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Peter D Karp Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Csac1394711Cyc: Candidatus Saccharibacteria bacterium RAAC3_TM7_1 Cellular Overview Connections between pathways are omitted for legibility. Tim Holland TM7C00001G0420 TM7C00001G0109 TM7C00001G0953 TM7C00001G0666 TM7C00001G0203 TM7C00001G0886 TM7C00001G0113 TM7C00001G0247 TM7C00001G0735 TM7C00001G0001 TM7C00001G0509 TM7C00001G0264 TM7C00001G0176 TM7C00001G0342 TM7C00001G0055 TM7C00001G0120 TM7C00001G0642 TM7C00001G0837 TM7C00001G0101 TM7C00001G0559 TM7C00001G0810 TM7C00001G0656 TM7C00001G0180 TM7C00001G0742 TM7C00001G0128 TM7C00001G0831 TM7C00001G0517 TM7C00001G0238 TM7C00001G0079 TM7C00001G0111 TM7C00001G0961 TM7C00001G0743 TM7C00001G0893 TM7C00001G0630 TM7C00001G0360 TM7C00001G0616 TM7C00001G0162 TM7C00001G0006 TM7C00001G0365 TM7C00001G0596 TM7C00001G0141 TM7C00001G0689 TM7C00001G0273 TM7C00001G0126 TM7C00001G0717 TM7C00001G0110 TM7C00001G0278 TM7C00001G0734 TM7C00001G0444 TM7C00001G0019 TM7C00001G0381 TM7C00001G0874 TM7C00001G0318 TM7C00001G0451 TM7C00001G0306 TM7C00001G0928 TM7C00001G0622 TM7C00001G0150 TM7C00001G0439 TM7C00001G0233 TM7C00001G0462 TM7C00001G0421 TM7C00001G0220 TM7C00001G0276 TM7C00001G0054 TM7C00001G0419 TM7C00001G0252 TM7C00001G0592 TM7C00001G0628 TM7C00001G0200 TM7C00001G0709 TM7C00001G0025 TM7C00001G0846 TM7C00001G0163 TM7C00001G0142 TM7C00001G0895 TM7C00001G0930 Detoxification Carbohydrate Biosynthesis DNA combined with a 2'- di-trans,octa-cis a 2'- Amino Acid Degradation an L-methionyl- TM7C00001G0190 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E.
    [Show full text]