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April 6, 2021 u vol. 118 u no. 14 From the Cover e2021311118 Ancient origins of oral venom e2021535118 Tornado strength and damage-based ratings e2013894118 Evaluating oil and gas well integrity e2013097118 Health benefits of natural sounds e2016337118 Invasive species in the global pet trade Contents THIS WEEK IN PNAS—This week’s research highlights Cover image: Pictured is a Bornean eiti1421118 In This Issue keeled pit viper (Tropidolaemus subannulatus). Agneesh Barua and — Alexander S. Mikheyev examined gene CORE CONCEPTS A brief introduction to emerging topics in science regulatory networks associated with e2104652118 Muography offers a new way to see inside a multitude of objects toxin production in snakes and found David Adam a metavenom network composed of more than 3,000 housekeeping genes. RETROSPECTIVE The findings suggest that snakes likely – developed venom from an ancient oral e2103938118 Alexander Spirin (1931 2020): A visionary scientist, a teacher, secretory system that was adapted to a colleague, a friend handle high protein loads. This ancient Valentina Evdokimova, Yuri Svitkin, and Nahum Sonenberg system is conserved between reptiles and mammals, suggesting that many COMMENTARIES mammals may harbor the potential to ’ become venomous under the right e2102056118 A slime mold s remembrance of things past conditions. See the article by Barua and Robert H. Austin Mikheyev, e2021311118. Image credit: See companion article, e2007815118, in vol. 118, issue 10 Anton Sorokin (photographer). e2102057118 Metabolic plasticity allows cancer cells to thrive under nutrient starvation Wilhelm Palm See companion article, e2003014118, in vol. 118, issue 10 e2102055118 Why does passion matter more in individualistic cultures? Jeanne L. Tsai See companion article, e2016964118, in vol. 118, issue 11 PERSPECTIVE e2020893118 Climate change and state evolution Giacomo Benati and Carmine Guerriero LETTERS e2100662118 No evidence that collective-good appeals best promote COVID-related health behaviors Nathaniel Rabb, David Glick, Attiyya Houston, Jake Bowers, and David Yokum e2102054118 Reply to Rabb et al.: Why promoting COVID-19 vaccines with community immunity is not a good strategy (yet) Lars Korn, Robert Bo¨hm, and Cornelia Betsch Free online through the PNAS open access option. PNAS u April 6, 2021 u vol. 118 u no. 14 u iii–vii Downloaded by guest on October 1, 2021 EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES BRIEF REPORTS e2007797118 Reconciling early Deccan Traps CO2 e2020258118 Task-specific information outperforms outgassing and pre-KPB global climate surveillance-style big data in Andres Hernandez Nava, Benjamin A. Black, Sally A. predictive analytics Gibson, Robert J. Bodnar, Paul R. Renne, Andreas Bjerre-Nielsen, Valentin Kassarnig, David and Loy¨c Vanderkluysen Dreyer Lassen, and Sune Lehmann e2021535118 Supercell tornadoes are much stronger and e2025739118 Deep genetic affinity between coastal Pacific wider than damage-based ratings indicate and Amazonian natives evidenced by Joshua Wurman, Karen Kosiba, Trevor White, Australasian ancestry and Paul Robinson Marcos Arau´jo Castro e Silva, Tiago Ferraz, Maria e2021810118 Fluid-like elastic response of superionic NH in Ca´tira Bortolini, David Comas, and Ta´bita Hu¨nemeier 3 Uranus and Neptune Tomoaki Kimura and Motohiko Murakami PHYSICAL SCIENCES ENGINEERING APPLIED PHYSICAL SCIENCES e2023141118 Deep generative selection models of T and B e2023807118 Imaging in vivo acetylcholine release in the cell receptor repertoires with soNNia peripheral nervous system with Giulio Isacchini, Aleksandra M. Walczak, Thierry Mora, a fluorescent nanosensor and Armita Nourmohammad Junfei Xia, Hongrong Yang, Michelle Mu, Nicholas Micovic, Kira E. Poskanzer, James R. Monaghan, e2014694118 Molecular mechanism of abnormally large and Heather A. Clark nonsoftening deformation in a tough hydrogel e2023181118 Invariant plastic deformation mechanism in Ya Nan Ye, Kunpeng Cui, Wei Hong, Xueyu Li, – Chengtao Yu, Dominique Hourdet, Tasuku Nakajima, paramagnetic nickel iron alloys Takayuki Kurokawa, and Jian Ping Gong Zhihua Dong, Wei Li, Stephan Scho¨necker, Bin Jiang, and Levente Vitos e2019292118 Vapor condensation with daytime radiative cooling ENVIRONMENTAL SCIENCES Ming Zhou, Haomin Song, Xingyu Xu, Alireza Shahsafi, e2013894118 Public data from three US states provide new Yurui Qu, Zhenyang Xia, Zhenqiang Ma, Mikhail A. Kats, Jia Zhu, Boon S. Ooi, Qiaoqiang Gan, insights into well integrity and Zongfu Yu Greg Lackey, Harihar Rajaram, James Bolander, Owen A. Sherwood, Joseph N. Ryan, Chung Yan Shih, e2024837118 Tuning interactions between spins in Grant S. Bromhal, and Robert M. Dilmore a superconductor Hao Ding (丁浩), Yuwen Hu, Mallika T. Randeria, Silas PHYSICS Hoffman, Oindrila Deb, Jelena Klinovaja, Daniel Loss, and Ali Yazdani e2011174118 Self-shaping liquid crystal droplets by balancing bulk elasticity and interfacial tension e2025317118 Hidden order and multipolar exchange Karthik Peddireddy, Simon Copar, Khoa V. striction in a correlated f-electron system Le, Igor Musevic, Christian Bahr, Leonid V. Pourovskii and Sergii Khmelevskyi and Venkata. S. R. Jampani BIOPHYSICS AND COMPUTATIONAL BIOLOGY e2019348118 “Extraordinary” modulation instability in optics e2018966118 Interplays of electron and nuclear motions and hydrodynamics along CO dissociation trajectory in myoglobin Guillaume Vanderhaegen, Corentin Naveau, Pascal revealed by ultrafast X-rays and quantum Szriftgiser, Alexandre Kudlinski, Matteo Conforti, dynamics calculations Arnaud Mussot, Miguel Onorato, Stefano Trillo, Amin Chabchoub, and Nail Akhmediev Megan L. Shelby, Andrew Wildman, Dugan Hayes, Michael W. Mara, Patrick J. Lestrange, Marco e2021794118 A jamming plane of sphere packings Cammarata, Lodovico Balducci, Maxim Artamonov, Yuliang Jin and Hajime Yoshino Henrik T. Lemke, Diling Zhu, Tamar Seideman, Brian M. e2022884118 Structural relaxation and crystallization in Hoffman, Xiaosong Li, and Lin X. Chen supercooled water from 170 to 260 K e2016623118 Overdispersion in COVID-19 increases the Loni Kringle, Wyatt A. Thornley, Bruce D. Kay, effectiveness of limiting nonrepetitive and Greg A. Kimmel contacts for transmission control e2025870118 Van der Waals interaction affects wrinkle Kim Sneppen, Bjarke Frost Nielsen, Robert J. Taylor, formation in two-dimensional materials and Lone Simonsen Pablo Ares, Yi Bo Wang, Colin R. Woods, James Dougherty, Laura Fumagalli, Francisco Guinea, Benny CHEMISTRY Davidovitch, and Kostya S. Novoselov e2021893118 In situ small-angle X-ray scattering reveals – solution phase discharge of Li O2 batteries SUSTAINABILITY SCIENCE with weakly solvating electrolytes e2020431118 A coupled human–natural system analysis of Christian Prehal, Aleksej Samojlov, Manfred freshwater security under climate and Nachtnebel, Ludek Lovicar, Manfred Kriechbaum, Heinz Amenitsch, and Stefan A. Freunberger population change Jim Yoon, Christian Klassert, Philip Selby, Thibaut e2100165118 Turn-on mode diarylethenes for bioconjugation Lachaut, Stephen Knox, Nicolas Avisse, Julien and fluorescence microscopy of Harou, Amaury Tilmant, Bernd Klauer, Daanish Mustafa, cellular structures Katja Sigel, Samer Talozi, Erik Gawel, Josue Kakishi Uno, Ayse Aktalay, Mariano L. Bossi, Masahiro Medellı´n-Azuara, Bushra Bataineh, Hua Zhang, Irie, Vladimir N. Belov, and Stefan W. Hell and Steven M. Gorelick iv u www.pnas.org Contents Downloaded by guest on October 1, 2021 SOCIAL SCIENCES BIOLOGICAL SCIENCES ECONOMIC SCIENCES APPLIED BIOLOGICAL SCIENCES e2023185118 Twenty-year economic impacts of deworming e2023807118 Imaging in vivo acetylcholine release in the Joan Hamory, Edward Miguel, Michael Walker, peripheral nervous system with Michael Kremer, and Sarah Baird a fluorescent nanosensor Junfei Xia, Hongrong Yang, Michelle Mu, Nicholas ENVIRONMENTAL SCIENCES Micovic, Kira E. Poskanzer, James R. Monaghan, and Heather A. Clark e2020431118 A coupled human–natural system analysis of freshwater security under climate and population change BIOCHEMISTRY Jim Yoon, Christian Klassert, Philip Selby, Thibaut e2026656118 Structural analyses of an RNA stability element Lachaut, Stephen Knox, Nicolas Avisse, Julien interacting with poly(A) Harou, Amaury Tilmant, Bernd Klauer, Daanish Mustafa, Seyed-Fakhreddin Torabi, Yen-Lin Chen, Kaiming Katja Sigel, Samer Talozi, Erik Gawel, Josue Zhang, Jimin Wang, Suzanne J. DeGregorio, Anand T. Medellı´n-Azuara, Bushra Bataineh, Hua Zhang, Vaidya, Zhaoming Su, Suzette A. Pabit, Wah Chiu, Lois and Steven M. Gorelick Pollack, and Joan A. Steitz e2013097118 A synthesis of health benefits of natural e2022756118 Structure of Gcn1 bound to stalled and sounds and their distribution in colliding 80S ribosomes national parks Agnieszka A. Pochopien, Bertrand Beckert, Sergo Rachel T. Buxton, Amber L. Pearson, Claudia Allou, Kasvandik, Otto Berninghausen, Roland Beckmann, Kurt Fristrup, and George Wittemyer Tanel Tenson, and Daniel N. Wilson e2018251118 CLK1 reorganizes the splicing factor POLITICAL SCIENCES U1-70K for early spliceosomal e2022634118 Diversity in health care institutions reduces protein assembly Israeli patients’ prejudice toward Arabs Brandon E. Aubol, Jacob M. Wozniak, Laurent Fattet, Chagai M. Weiss David J. Gonzalez, and Joseph A. Adams e2009086118 Using random assignment to measure e2024846118 Substrate discrimination and quality control court accessibility for low-income require each catalytic activity of TRAMP divorce seekers and the nuclear RNA exosome D. James Greiner, Ellen Lee Degnan,