TBL1X Antibody Cat. No.: 15-880

TBL1X Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human IMMUNOGEN: TBL1X (NP_005638.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) BxPC-3

2) HeLa

3) mouse brain

4) mouse lung

PREDICTED MOLECULAR Observed: 60kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

October 2, 2021 1 https://www.prosci-inc.com/tbl1x-antibody-15-880.html ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: TBL1X

TBL1X, EBI, TBL1, transducin (beta)-like 1X-linked, transducin (beta)-like 1, transducin ALTERNATE NAMES: (beta)-like 1 X-linked, TBL1XR1, transducin (beta)-like 1X-linked receptor 1, C21, DC42, FLJ12894, IRA1, TBLR1, TBL1-related protein 1, nuclear receptor co-repressor

GENE ID: 6907

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is BACKGROUND: found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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October 2, 2021 2 https://www.prosci-inc.com/tbl1x-antibody-15-880.html