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CARLO URBANI Project CARLO URBANI project 2007 / 2017 HUE UNIVERSITY OF MEDICINE AND PHARMACY 06 Ngo Quyen Str., Hue City, 530000, Vietnam Tel: +84.234.382217 - Fax: +84.234.3826269 huemed-univ.edu.vn - hcmp@huemed -univ.edu.vn PAGE COVERBACK CARLO URBANI PROJECT 06 Ngo Quyen Str. Hue City, 530000, Vietnam Tel: +84.234.382217 / Fax: +84.234.3826269 www.carlo-urbani-center.com 2 OUTLINE REPORT OF CARLO URBANI project 2007 / 2017 CONTENT About the project 1 About Dr. Carlo Urbani 2 Timeline of the project 3 Phase I 4 Activities & outcome 4 Opening ceremony of project 5 Infrastructure building 7 Inauguration of Carlo Urbani Center 9 Training activities 10 Short training courses 10 Research activities 14 Phase II 17 Activities & outcome 17 Infrastructure & Inauguration of new ICU 15 Training activities 19 Short training for new ICU staff 19 Initiation of biomedicine institute 20 Phase III 22 Activities & outcome 22 Joint International Master course in medical Biotechnology 23 The PhD Course in Life Sciences and Biotechnologies 28 Other activies 30 Short training courses of biotechnolgy for high-school teachers 30 10 year Anniversary of Dr. Carlo Urbani’ death 32 Science festivals in Hue Festivals 39 Publication 44 4 About Carlo Urbani Project The project "Organization of a training, research and reference center for the control of respiratory infections in Central Vietnam dedicated to the memory of Carlo Urbani " orginated from a real need of the Vietnamese health system and from the willingness to promote an initiative in the health sector, aimed at prevention and control of highly contagious acute respiratory infections that, at the same time could remember Carlo Urbani decisive commitment, until his sacrifice, for the control of SARS outbreak that struck Vietnam in 2003. In agreement with the Italian Embassy and Italian Cooperation office in Vietnam it was decided to locate the initiative in central Vietnam, at that time an area without BSL3 facilities and with limited training initiatives, taking advantage from the collaboration that the University of Sassari (UNISS) had established, since a number of years, with the University of Hue and particularly with the University of Medicine and Pharmacy (HUMP). The execution of the project was entrusted to a Consortium comprising UNISS, the AISPO / San Raffaele NGO, the San Salvatore Hospital in Pesaro and AICU (Italian Association Carlo Urbani) and the first phase of the project, co-funded by the Italian Cooperation, started in October 2007. In February this year the third and final stage was concluded, and among the events for the celebration for the 60th anniversary of the University of Hue, there will be the official closing of the project with a scientific symposium and presentation of the results. The objectives of the Center's activities were aimed at improving the control of respiratory infections including the epidemiological surveillance system, the laboratory diagnosis, the clinical diagnosis and treatment of respiratory infections, the professional qualification, scientific training and health management skills of medical and paramedical staff, researcher and teacher and finally, the development of biomedical and clinical research on infections and their etiological agents. 1 Dr. Carlo Urbani I 1956 - 2003 n 2004, the SARS (Severe Acute Respiratory Syndrome) outbreak started in Hong Kong and rapidly spread to Vietnam and other countries. Dr. Carlo Urbani, an Italian expert working for WHO, died of SARS when fighting against the virus in Vietnam. To remember of his heroic sacrifice, the Italian Government and Italian Cooperation supported the building of a center under his name for surveillance and control on respiratory infections, the Carlo Urbani Center at HUMP. 2 TIMELINE The organization of the project in three phases, interspersed with periods in which the activities were still going ahead, although to a lesser extent, allowed to give a multi- year intervention breath and gradually consolidate the results obtained. The general activities developed under the project have been: training and technical assistance, the reorganization and improvement of infrastructure and the supply of equipment, technology transfer and promoting biomedical research. 758.890 € Total 349.890 € Italian Cooperation 125.000 € Sardinia Research Agency 143.500 € UNISS-AISPO 140.500 € HUMP Phase III Nov 2013 - Feb 2017 Feb 2010 - Dec 2012 Phase 1.473.966 € Total II 996. 516 € Italian Cooperation 280.650 € Italian Consortium 196.800 € HUMP Oct 2007 - Jan 2009 Phase I 1.277.318 € in Total 839.424 € Italian Cooperation 261.394 € Italian Consortium 176.500 € HUMP 3 PHASE 1 October 2007- January 2009 ACTIVITIES & OUTCOME ▪ A laboratory for molecular diagnosis and cell cultures with a sector at BSL3 level located in Department of Microbiology ▪ A conference room with distance learning facilities ▪ Equipment for diagnosis, research and distance learning purchase and provided ▪ Eight training courses for doctors and health personnel from 9 provinces of Central Vietnam (total about 180 persons) ▪ Short training courses in Italy for 6 doctors and nurses ▪ Two doctors admitted to PhD course in Italy ▪ International Seminar on Emerging and re-emerging respiratory infections ▪ Grants for research projects on infectious diseases 4 Opening ceremony of project Opening ceremony of the project Visit to the location area for Carlo Urbani Center of Italian Ambassador 5 Meeting with UNISS Meeting with AISPO 6 Infrastructure building The first phase was focused on establishing microbiological laboratories for detection of respiratory pathogens causing acute respiratory infections in Thua Thien Hue province, including some highly contagious pathogens such as SARS-CoV and multidrug resistant Mycobacterium tuberculosis, … Setting up a molecular microbiology diagnostic lab in an area of nearly 300 square meters with two BSL3 laboratories for identification of respiratory infections in Hue UMP. Carlo Urbani Center plan 7 Setting up of the ventilation and filter system for BSL3 The construction started in Oct 2008 and was terminated in March 2009. The BSL3 was certified by an international company from Singapore. Setting up of the control room for BSL3 8 Inauguration of Carlo Urbani Center Inauguration of Carlo Urbani Center with the presence of Vice-Minister of Health, Italian Ambassador and TT Hue province and University authorities A B C Carlo Urbani Center Facilities A. Cell culture laboratory B. BLS3 Bacteriology laboratory C. BLS3 Virology laboratory 9 TRAINING ACTIVITIES Short training courses Improving the capacity of health workers in central Vietnam Training on laboratory diagnosis, surveillance and control of respiratory infections for health staff of HUMP and of 9 provinces in the central Vietnam, from Quang Binh to Khanh Hoa province. Quang Binh Quang Tri Thua Thien Hue Da Nang Quang Nam Quang Ngai Binh Dinh Phu Yen Khanh Hoa Map of Provinces included in training 10 Short training courses in Carlo Urbani Center LIST OF SHORT TRAINING COURSES IN PHASE 1 Laboratory diagnosis of microbial pathogens in Mar 2008 respiratory tract infection Laboratory diagnosis of viral respiratory infections Mar 2008 Practice in use SPSS software in science research Mar 2008 Molecular biological methods applied in diagnosis of Jun 2008 pathogens of respiratory infections Laboratory diagnosis of Mycobacteria tuberculosis Sept 2008 complex Methodology of research in medicine Sept 2008 Basis of Cardio-Respiratory Resuscitation Nov 2008 Acute respiratory infection in ICU Now 2008 11 Improving the capacity of young doctors of Carlor Urbani Center staffs Specialized trainings for junior doctors working in the Carlo Urbani centre in Hue University were also offered by sending them to many Italian Universities and Hospitals. Duration of specialized training was three months and six juniors were selected for training in microbiological diagnosis and intensive care management. Sending young doctors of HUMP for training in microbiology diagnostics and clinical management of respiratory infections in Italy. Dr. Bao Chi and San Raffaele Hospital Staff, Milan, Italy Dr. Tam and San Raffaele Hospital Staff, Milan, Italy Dr. Chau Anh at Gemelli Univ. Polyclinic, Rome, Italy 12 PhD Program between UNISS and Hue UMP Dr. Quynh Tram in lab of Clinical Microbiology, UNISS In 2009 the first two doctors from the Department of Microbiology of HUMP were enrolled in the PhD School in Biomolecular and Biotechnological Sciences of UNISS and in the following year another doctor from the Department of Parasitology entered the same school. All of them were supported by the Carlo Urbani Project during the time spent in Italy until the final exams for obtaining the PhD title. Dr. Le Van An in final presentation of PhD thesis at UNISS 13 RESEARCH ACTIVITIES Research projects on epidemiology of influenza virus and drug resistant Mycobacterium tuberculosis Area of research in this phase ▪ Investigation on viral etiologies of respiratory infections ▪ Characterization of influenza A H1N1 pdm virus in 2009 ▪ MOSD method and PCR techniques for detection of Mycobacterium tuberculosis ▪ Spoligotyping and multidrug resistance of TB complex in central Vietnam 14 International symposium on emerging and re-emerging respiratory infections An international symposium on Emerging and reemerging infectious diseases vas organized on Nov 2008 with the participation of scientists from Italy, Vietnam, Canada, China, France, United Kingdom and made connections for future collaboration on training
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