Anti-CYP4F12 (aa 133-322) polyclonal antibody (DPABH-22566) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description CYP4F12 catalyzes leukotriene B4 omega-hydroxylation and arachidonic acid omega- hydroxylation but with an activity much lower than that of CYP4F2. It also catalyzes the hydroxylation of the antihistamine ebastine. CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Immunogen Recombinant fragment, corresponding to internal sequence amino acids 133 - 322 of Human CYP4F12 (Q9HCS2)
Isotype IgG
Source/Host Rabbit
Species Reactivity Human
Purification Immunogen affinity purified
Conjugate Unconjugated
Applications WB
Format Liquid
Size 50 μl
Buffer pH: 7.00; Constituents: 78% PBS, 20% Glycerol, 1% BSA
Preservative None
Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
GENE INFORMATION
Gene Name CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 [ Homo sapiens ]
Official Symbol CYP4F12
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms CYP4F12; cytochrome P450, family 4, subfamily F, polypeptide 12; cytochrome P450, subfamily IVF, polypeptide 12; cytochrome P450 4F12; CYPIVF12; F22329_1;
Entrez Gene ID 66002
Protein Refseq NP_076433
UniProt ID Q9HCS2
Chromosome Location 19p13.1
Pathway Biological oxidations; Cytochrome P450 - arranged by substrate type; Fatty acids; Metabolism; Phase 1 - Functionalization of compounds; Tryptophan metabolism;
Function alkane 1-monooxygenase activity; arachidonic acid epoxygenase activity; aromatase activity; electron carrier activity; heme binding; leukotriene-B4 20-monooxygenase activity; metal ion binding
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved