Squay Bayesian Analysis of SARS
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Progress Report on a Pandemic
The international journal of science / 20 August 2020 other diseases were more likely to be admitted to intensive care, whereas children seemed to have milder disease4. Progress report But it quickly became apparent that SARS-CoV-2 is not just a respiratory virus. It also affects blood vessels, causing on a pandemic thrombosis5 and strokes6. Autopsies have found the virus in organs other than the lungs, including the kidneys, liver, heart and brain, In the first of a series of editorials, we as well as in the blood7. We now know that symptoms of look back at some of the key findings COVID-19 can include gastrointestinal, neurological, renal, from scientists’ race to demystify the new cardiovascular and other complications8. coronavirus. Something in the air n the space of eight months, the new coronavirus It soon became clear that SARS-CoV-2 could hop from SARS-CoV-2 and the disease it causes, COVID-19, have one person to another. This could happen through direct dominated the work of thousands of researchers in an contact or indirect transmission, such as through drop- unprecedented global effort. lets expelled during a cough, or even a simple exhalation. In a series of editorials, we look back at key scientific What wasn’t clear — and is still a matter of debate — is how Ifindings that have revealed important characteristics of big those droplets need to be, and how far they can travel. the virus and COVID-19, including emerging approaches to It’s an important question. Larger droplets will quickly treatment and prevention. We begin, this week, with how fall to the ground, but smaller, lighter ones — known as aer- the virus was identified; how it transmits between people; osols — can stay suspended in the air. -
June 11, 2021 the Honorable Xavier Becerra Secretary Department of Health and Human Services 200 Independence Ave S.W. Washingto
June 11, 2021 The Honorable Xavier Becerra Secretary Department of Health and Human Services 200 Independence Ave S.W. Washington, D.C. 20201 The Honorable Francis Collins, M.D., Ph.D. Director National Institutes of Health 9000 Rockville Pike Rockville, MD 20892 Dear Secretary Becerra and Director Collins, Pursuant to 5 U.S.C. § 2954 we, as members of the United States Senate Committee on Homeland Security and Governmental Affairs, write to request documents regarding the National Institutes of Health’s (NIH) handling of the COVID-19 pandemic. The recent release of approximately 4,000 pages of NIH email communications and other documents from early 2020 has raised serious questions about NIH’s handling of COVID-19. Between June 1and June 4, 2021, the news media and public interest groups released approximately 4,000 pages of NIH emails and other documents these organizations received pursuant to Freedom of Information Act requests.1 These documents, though heavily redacted, have shed new light on NIH’s awareness of the virus’ origins in the early stages of the COVID- 19 pandemic. In a January 9, 2020 email, Dr. David Morens, Senior Scientific Advisor to Dr. Fauci, emailed Dr. Peter Daszak, President of EcoHealth Alliance, asking for “any inside info on this new coronavirus that isn’t yet in the public domain[.]”2 In a January 27, 2020 reply, Dr. Daszak emailed Dr. Morens, with the subject line: “Wuhan novel coronavirus – NIAID’s role in bat-origin Covs” and stated: 1 See Damian Paletta and Yasmeen Abutaleb, Anthony Fauci’s pandemic emails: -
Melissaossmanpro.Pdf
August 19, 2021 Chairman Lipps, Vice Chair Holmes, Ranking Member Russo, and Members of the House Health Committee, thank you for the opportunity to provide proponent testimony on House Bill 248. My family and I are asking that Ohio HB248 be passed in order to protect the individual freedoms we currently have as American citizens. I work in a corporate setting and my husband owns a small business. We have two young daughters who are relying on us to provide for them and protect their rights. I support this bill in hopes that they can grow up with the same liberties we have had. Segregation and discrimination over individual health choices should be taken seriously and passing this bill is key to avoiding those types of issues in the future. I am not a scientist, but I am a mom, a wife, and a daughter who takes the health of my family very seriously. I have done extensive amounts of research on the SARS-COV2 virus and subsequent vaccines. There are also many health experts that provide me with helpful information. I am sure you are receiving many testimonies about the large numbers of vaccine injuries and even deaths that have occurred during this vaccine campaign. Personally, I know two women who have had severe menstrual issues (requiring surgery) that they can connect back to occurring right after the vaccine. My friends’ cousin passed away at only 23 years old from an enlarged heart after receiving the vaccine. The stories go on and on. The point is that no legislation should force my family and I to inject ourselves with substances that have side effects such as this. -
The Highly Pathogenic Avian Influenza A(H5N1) Virus: a Twenty-Year Journey of Narratives and (In)Secure Landscapes
The Highly Pathogenic Avian Influenza A(H5N1) Virus: a twenty-year journey of narratives and (in)secure landscapes Philip Rolly Egert Dissertation submitted to the faculty of the Virginia Polytechnic Institute and State University in partial fulfillment of the requirements for the degree of Doctor of Philosophy In Science, Technology, and Society Barbara L. Allen (Chair) Daniel Breslau Bernice L. Hausman David C. Tomblin March 18, 2016 Falls Church, Virginia Keywords: H5N1, HPAI, highly pathogenic avian influenza virus, pandemic, social justice, bioterrorism, bioethics, biopower, tacit knowledge, dual-use dilemma, dual-use research of concern, emerging infectious disease Copyright Philip R. Egert The Highly Pathogenic Avian Influenza A(H5N1) Virus: a twenty-year journey of narratives and (in)secure landscapes Philip Rolly Egert ABSTRACT This dissertation is comprised of two manuscripts that explore various contestations and representations of knowledge about the highly pathogenic avian influenza H5N1virus. In the first manuscript, I explore three narratives that have been produced to describe the 20-year journey of the virus. The journey begins in 1996 when the virus was a singular localized animal virus but then over the next 20 years multiplied its ontological status through a (de)stabilized global network of science and politics that promoted both fears of contagion and politics of otherness. Written by and for powerful actors and institutions in the global North, the narratives focused on technical solutions and outbreak fears. In doing so, the narratives produced policies and practices of biopower that obscured alternative considerations for equity, social justice, and wellbeing for the marginalized groups most directly affected by the H5N1 virus. -
Emergence of Highly Infectious SARS-Cov-2 Variants in Bangladesh
Hasan et al. Trop Med Health (2021) 49:69 https://doi.org/10.1186/s41182-021-00360-w Tropical Medicine and Health LETTER TO THE EDITOR Open Access Emergence of highly infectious SARS-CoV-2 variants in Bangladesh: the need for systematic genetic surveillance as a public health strategy Mohammad Mehedi Hasan1,2, Ian Christopher N. Rocha3, Kimberly G. Ramos3, Trisha Denise D. Cedeño3, Ana Carla dos Santos Costa4, Christos Tsagkaris5, Md. Masum Billah6, Shoaib Ahmad7 and Mohammad Yasir Essar8* Abstract Bangladesh, a low-middle-income country in South Asia is facing one of its worst public health emergencies due to the COVID-19 pandemic. The increase in the number of cases from the disease, since the second half of March 2021, can potentially cause the health system overload, and has, as one of the main reasons, the non-compliance with measures of social distance and the emergence of the variants of concern in the country. This increase in the contagion curve can also provide a favorable environment for the occurrence of more mutations in the structure and genome of the virus. Therefore, there is an urge to carry out genomic surveillance programs in order to identify, moni- tor and characterize these variants, and understand whether the vaccines currently used are efective against them. Keywords: Bangladesh, SARS-CoV-2 variants, Public health, Genetic surveillance Dear editor, in the country began to increase during the middle of Te ongoing Coronavirus Disease 2019 (COVID-19) March 2021. Initially, there was a drop in the number of pandemic is a major burden to health systems world- cases during February 2021, in which the lowest monthly wide, constituting the worst health crisis in history. -
Medical JOUR
RHODE ISLAND M EDiCAL J ournal ZOOM – It’s a Match! Virtual National Match Day is largest on record See page 75 R SPECIAL SECTION, PART II BIOMEDICAL/TRANSLATIONAL RESEARCH in RI GUEST EDITORS: JAMES PADBURY, MD; BONGSUP CHO, PhD ApRiL 2021 VOLUME 104 • NUMBER 3 iSSN 2327-2228 REINVENTING WHAT YOU EXPECT FROM A MEDICAL PROFESSIONAL LIABILITY PROVIDER. With Coverys, you can reduce the distractions that come between diagnosis and outcomes. By leveraging claims data and analytics plus innovative educational resources, we’re helping doctors and administrators reduce distractions and focus on improving clinical, operational, and financial outcomes.Visit coverys.com Insurance products issued by ProSelect® Insurance Company (NE, NAIC 10638) and Preferred Professional Insurance Company® (NE, NAIC 36234). RHODE ISLAND M EDICAL J OURNAL 15 Translational Research: The Time is Now JAMES F. PADBURY, MD BONGSUP P. CHO, PhD GUEST EDITORS James F. Padbury, MD Bongsup Cho, PhD 17 The Time is NOW: Filling the Gaps in Treatment of Opioid-Exposed Infants: A Prospective, Pragmatic, Randomized Control Drug Trial ADAM J. CZYNSKI, DO; ABBOT R. LAPTOOK, MD 22 COBRE on Opioid and Overdose: A Collaborative Research-Based Center Addressing the Crises in Rhode Island and Beyond TRACI C. GREEN, PhD, MSc; ELIANA KAPLOWITZ, BA; KIRSTEN LANGDON, PhD; JACLYN M.W. HUGHTO, PhD, MPH; WILLIAM C. GOEDEL, PhD; ADAM J. CZYNSKI, DO; GAYLE FRASER, BS; JOSIAH RICH, MD, MPH 27 Brown University COBRE Center for Addiction and Disease Risk Exacerbation PETER M. MONTI, PhD; JENNIFER W. TIDEY, PhD; JASJIT S. AHLUWALIA, MD 32 The Center of Biomedical Research Excellence (COBRE) for Perinatal Biology – Accomplishments, Impact, and Long-term Results SUNIL K. -
Peter Daszak IPBES Scoping for the Nexus Assessment: Health
IPBES Scoping for the Nexus Assessment: Health & Linkages Peter Daszak [email protected] The focus for this session Three thematic areas: 1. Biodiversity & health 2. Global environmental change & health 3. Food, water & health Your suggestions on: • Scope of the assessment • Questions to address Post-2020 Biodiversity Framework and Global Goals . Aichi Biodiversity Targets, particularly: • Target 14. Biodiversity and Ecosystem Services . Sustainable Development Goals, e.g.: • 3. Health; • 6. Clean Water and Sanitation; • 13. Climate Action; • 14. Aquatic Ecosystems; • 15. Terrestrial Ecosystems; • 17. Partnerships . Global Health Security Agenda (Prevent, Detect, Respond) . Sendai Framework for Disaster Risk Reduction 2015-2030 • Bangkok Principles for implementation of health aspects One Health approach • Health of people, wildlife, livestock, environment • Impact of human-mediated global environmental change on health across all sectors Biodiversity’s Health Services Pharmaceuticals • Penicillin (fungus); Digitalis (foxglove plant); Quinine and quinidine (Peruvian Cinchona tree); Morphine and codeine (poppies); Taxol (Pacific Yew tree) Welfare • Link between good mental health and open spaces, biodiversity, forests/parks • Outdoor activity linked to overall fitness and lack of disease • Dietary diversity and nutritional health Protection against disease • Lower risk emerging diseases from undisturbed intact forest Honey Bee Declines in U.S.A. Biodiversity loss & health Intact Forest Residential Urban Culex mosquitoes prefer -
1. Sars-Cov Nucleocapsid Protein Epitopes and Uses Thereof
www.engineeringvillage.com Citation results: 500 Downloaded: 4/24/2020 1. SARS-COV NUCLEOCAPSID PROTEIN EPITOPES AND USES THEREOF KELVIN, David; PERSAD, Desmond; CAMERON, Cheryl; BRAY, Kurtis, R.; LOFARO, Lori, R.; JOHNSON, Camille; SEKALY, Rafick-Pierre; YOUNES, Souheil-Antoine; CHONG, Pele Assignee: UNIVERSITY HEALTH NETWORK; BECKMAN COULTER, INC.; UNIVERSITE DE MONTREAL; NATIONAL HEALTH RESEARCH INSTITUTES Publication Number: WO2005103259 Publication date: 11/03/2005 Kind: Patent Application Publication Database: WO Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data Provider: Engineering Village 2. SARS-CoV-specific B-cell epitope and applications thereof Wu, Han-Chung; Liu, I-Ju; Chiu, Chien-Yu Assignee: National Taiwan University Publication Number: US20060062804 Publication date: 03/23/2006 Kind: Utility Patent Application Database: US Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data Provider: Engineering Village 3. A RECOMBINANT SARS-COV VACCINE COMPRISING ATTENUATED VACCINIA VIRUS CARRIERS QIN, Chuan; WEI, Qiang; GAO, Hong; TU, Xinming; CHEN, Zhiwei; ZHANG, Linqi; HO, David, D. Assignee: INSTITUTE OF LABORATORY ANIMAL SCIENCE OF CHINESE ACADEMY OF MEDICAL SCIENCES; THE AARON DIAMOND AIDS RESEARCH CENTER; QIN, Chuan; WEI, Qiang; GAO, Hong; TU, Xinming; CHEN, Zhiwei; ZHANG, Linqi; HO, David, D. Publication Number: WO2006079290 Publication date: 08/03/2006 Kind: Patent Application Publication Database: WO Patents Compilation and indexing terms, 2020 LexisNexis Univentio B.V. Data -
ISSUE #9 from the Red Patriot Show Some Articles May Require Subscriptions
J E u l y H 1 T 4 The News t Red R eport h The People • The Right Way , ' 2 1 ISSUE #9 from The Red Patriot Show Some articles may require subscriptions CHINESE-MADE COVID-19 VACCINE RECIPIENTS WON’T COUNT AS VACCINATED: SINGAPORE The Epoch Times Singapore’s health agency said that individuals who have received the Chinese-made COVID-19 vaccine won’t count as being vaccinated. BIDEN ADMIN TO GO “The national vaccination numbers reflect only those vaccinated under the national vaccination program,” the country’s Ministry of ‘DOOR-TO-DOOR’ TO Health said on Tuesday. “Currently, this only includes those vaccinated VACCINATE PEOPLE with the Moderna COVID-19 and Pfizer-BioNTech/Comirnaty vaccines.” America's C itizen Press COVID-19 is the disease caused by the CCP (Chinese Communist Party) virus, otherwise known as the coronavirus. President Joe Biden’s administration plans to go door-to-door to vaccinate people against COVID-19. The city-state’s health officials said there is inadequate efficacy data for “Now we need to go to community-by-community, neighborhood- the Sinovac COVID-19 vaccine, namely against the Delta strain. The by-neighborhood, and oft-times door-to-door, literally knocking variant has become the most prevalent COVID-19 strain in the country. on doors,” said Biden. Watch Biden threaten to send government officials to your door to make you take an OPTIONAL vaccine. WATCH BIDEN While answering a question, Biden appeared to lose his train STRUGGLE TO of thought and completely SPEAK YET forget the name Osama Bin Laden for about five to six AGAIN seconds. -
Assessing SARS-Cov-2 Circulation, Variants of Concern, Non-Pharmaceutical Interventions and Vaccine Rollout in the EU/EEA, 15Th Update 10 June 2021
RISK ASSESSMENT Assessing SARS-CoV-2 circulation, variants of concern, non-pharmaceutical interventions and vaccine rollout in the EU/EEA, 15th update 10 June 2021 Summary Although SARS-CoV-2 transmission remains widespread in large parts of the EU/EEA, most countries report declining trends in 14-day COVID-19 notification rates, hospital and intensive care unit (ICU) occupancy, and mortality. Many countries have initiated partial lifting of different non-pharmaceutical interventions (NPIs) that aim to reduce the degree of citizens physical contact and mobility. Since January 2021, EU/EEA countries have reported an increase in the number and proportion of SARS-CoV-2 cases of variants of concern (VOC) associated with increasing transmissibility and/or severity, with Alpha (B.1.1.7) the current dominant variant across the EU/EEA. Estimates across the region show that a large proportion of the population across Europe still remains susceptible to SARS-CoV-2 and that population immunity is far from being reached. As of 3 June, the median cumulative vaccine uptake in the EU/EEA adult population (aged 18 years and older) had reached 46.2% for at least one vaccine dose and 22.3% for the full vaccination course. The highest level of vaccine uptake was observed among the elderly aged over 80, in which the uptake reached 80.5% for at least one dose and 66.3% for full vaccination coverage. For healthcare workers, the median level of at least one dose uptake was 87% and the median uptake for the full vaccination course was 65.2%. Increased vaccine supply has allowed countries to expand eligibility for vaccination to younger age groups. -
Doctors' Mental Health in the Midst of COVID-19 Pandemic
International Journal of Environmental Research and Public Health Article Doctors’ Mental Health in the Midst of COVID-19 Pandemic: The Roles of Work Demands and Recovery Experiences 1,2, 1, , 3 Mohd Fadhli Mohd Fauzi y , Hanizah Mohd Yusoff * y, Rosnawati Muhamad Robat , Nur Adibah Mat Saruan 1,2 , Khairil Idham Ismail 1,2 and Ahmad Firdaus Mohd Haris 4 1 Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia; [email protected] (M.F.M.F.); [email protected] (N.A.M.S.); [email protected] (K.I.I.) 2 Ministry of Health Malaysia, Federal Government Administrative Centre, Putrajaya 62590, Malaysia 3 Occupational and Environmental Health Unit, Selangor State Health Department, No 1, Wisma Sunway, Jalan Tengku Ampuan Zabedah C 9/C, Seksyen 9, Shah Alam, Selangor 40100, Malaysia; [email protected] 4 Non-Communicable Diseases Unit, Perak State Health Department, Jalan Koo Chong Kong, Ipoh 30000, Perak, Malaysia; ahmad.fi[email protected] * Correspondence: [email protected]; Tel.: +60-3-9145-5904 These authors contributed equally to this work. y Received: 18 September 2020; Accepted: 5 October 2020; Published: 8 October 2020 Abstract: The COVID-19 pandemic potentially increases doctors’ work demands and limits their recovery opportunity; this consequently puts them at a high risk of adverse mental health impacts. This study aims to estimate the level of doctors’ fatigue, recovery, depression, anxiety, and stress, and exploring their association with work demands and recovery experiences. This was a cross-sectional study among all medical doctors working at all government health facilities in Selangor, Malaysia. -
Social Distancing and Supply Disruptions in a Pandemic∗
Social Distancing and Supply Disruptions in a Pandemic∗ Martin Bodenstein Giancarlo Corsetti Luca Guerrieri Federal Reserve Board University of Cambridge Federal Reserve Board June 18, 2020 Abstract Drastic public health measures such as social distancing or lockdowns can reduce the loss of human life by keeping the number of infected individuals from exceeding the capacity of the health care system but are often criticized because of the social and economic costs they entail. We question this view by combining an epidemiological model, calibrated to capture the spread of the COVID-19 virus, with a multisector model, designed to capture key characteristics of the U.S. Input Output Tables. Our two-sector model features a core sector that produces intermediate inputs not easily replaced by inputs from the other sector, subject to minimum-scale requirements. We show that, by affecting workers in this core sector, the high peak of an infection not mitigated by social distancing may cause very large upfront economic costs in terms of output, consumption and investment. Social distancing measures can reduce these costs, especially if skewed towards non-core industries and occupations with tasks that can be performed from home, helping to smooth the surge in infections among workers in the core sector. JEL classifications: E1, E3, I1. Keywords: infectious disease, epidemic, recession, COVID-19. ∗ The views expressed in this paper are solely the responsibility of the authors and should not be interpreted as reflecting the views of the Board of Governors of the Federal Reserve System or of any other person associated with the Federal Reserve System.