A Hierarchical Location Normalization System for Text
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Next-Generation Sequencing Improves Thalassemia Carrier Screening Among Premarital Adults in a High Prevalence Population: the Dai Nationality, China
ORIGINAL RESEARCH ARTICLE © American College of Medical Genetics and Genomics Next-generation sequencing improves thalassemia carrier screening among premarital adults in a high prevalence population: the Dai nationality, China Jing He, MS1,2, Wenhui Song, PhD3, Jinlong Yang, BS3,5, Sen Lu, PhD4, Yuan Yuan, MS4, Junfu Guo, MS4, Jie Zhang, PhD2, Kai Ye, BS4, Fan Yang, BS4, Fangfang Long, MS3, Zhiyu Peng, PhD4, Haijing Yu, PhD5, Le Cheng, PhD3,6 and Baosheng Zhu, MS1,2 Purpose: Thalassemia is one of the most common monogenic dis- ite α- and β-thalassemia carriers were missed by traditional screens. eases in southwestern China, especially among the Dai ethnic group. The proportion of such α- and β-thalassemia carriers among the Dai Here, we explore the feasibility of a next-generation sequencing people is 8.6% (82/951). For β-thalassemia carriers, the high ratio (NGS) screening method specifically for the Dai people. (66/99) of CD26 mutations may suggest a correlation between CD26 Methods: Blood samples were obtained from Dai people for premar- and the environmental adaption of the Dai people. ital screening. Double-blind, parallel hemoglobinopathy screening Conclusions: Methodological comparisons demonstrate the superi- was conducted using both traditional hematological methods (red ority of NGS for both sensitivity and specificity, provide a compre- cell indexes and hemoglobin electrophoresis, then DNA sequencing) hensive assessment of thalassemia screening strategies, and indicate and an NGS approach. that NGS is a competitive screening method, especially among popu- Results: Among 951 tested individuals, we found a thalassemia car- lations with a high prevalence of disease. rier rate of 49.5% (471/951) using the NGS screen, in contrast to Genet Med advance online publication 26 January 2017 22.0% (209/951) found using traditional methods. -
Butte County MHMP Were Asked to Provide Ratings of the Likelihood That an Event Would Occur in the Future
BUTTE COUNTY MULTI-JURISDICTIONAL ALL HAZARD PRE-DISASTER MITIGATION PLAN MARCH 2007 Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) County of Butte i Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) City of Biggs ii Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 iii Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) City of Chico iv Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 v Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) City of Gridley v Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) City of Oroville vi Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 vii Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Adoption by Local Governing Body: §201.6(c)(5) Town of Paradise viii Butte County Multi-Jurisdictional All Hazard Pre-Disaster Mitigation Plan March 2007 Table of Contents 1. Purpose / Vision / Values .............................................................................................1 2. The Planning Process....................................................................................................3 -
Who Gets Promoted and Why? Understanding Power and Persuasion in China's Cadre Evaluation System
Who Gets Promoted and Why? Understanding Power and Persuasion in China’s Cadre Evaluation System Zhen Wang Department of Political Science Middle Tennessee State University Prepared for Delivery at the 2013 Annual Meeting of the American Association for Chinese Studies October 11-13, 2013 New Brunswick, New Jersey 1 Introduction The worldwide speculations that took place before China’s leadership change in 2012 suggest an uncomfortable fact that we know very little about how China’s political personnel system actually works. The authoritarian state is surely to blame for intentionally making the process secretive. But as political scientists, how do we move beyond guesswork and start making better sense of the system? What are the criteria that the Communist Party uses to promote or demote its officials? How are these criteria implemented? And what are the power mechanisms involved in the implementation process? A small group of political scientists have striven to make sense of this murky but highly important subject by examining either the Nomenklatura system at the central level or the Cadre Evaluation System (CES) at the level of sub- national governments. This paper seeks to contribute to this cause of a better understanding of the Communist Party’s personnel management system by further investigating the CES – a personnel management system that assesses the performance of leading local officials from the provincial down to the lowest local level. Based on six months of fieldwork combing interviews with archival research, I argue that China’s cadre evaluation system consists of two intrinsic power mechanisms – top-down control and local autonomy, and that there is more bargaining and negotiation involved in the cadre evaluation process than often assumed. -
Local Governments and Home Rule in South Carolina
Local Governments and Home Rule in South Carolina A Citizen’s Guide Holley Hewitt Ulbrich and Ada Louise Steirer Strom Thurmond Institute of Government and Public Affairs Clemson University Local Governments and Home Rule in South Carolina A Citizen’s Guide by Holley Hewitt Ulbrich Ada Louise Steirer June 2004 Strom Thurmond Institute of Government and Public Affairs Clemson University Funded by the R.C. Edwards Endowment and the Office of the President 1 Contents ◗ Before You Read This Booklet . Three ◗ Home Rule in South Carolina . Five ◗ Municipalities and Home Rule . Eight ◗ Counties and Home Rule. Fifteen ◗ School Districts and Home Rule . .Twenty-three ◗ Conclusion . Twenty-seven ◗ What Can a Citizen Do? . Twenty-eight About the Authors Dr. Ulbrich is Alumna Professor Emerita of Economics at Clemson University and Senior Fellow of the Strom Thurmond Institute. She has written extensively about tax policy. Ms. Steirer is a re- search associate in community and economic development at the Institute. Both have experience as elected and appointed officials. Cover photos provided by the city of Clemson, Clemson University’s Photo Lab, and the S.C. Association of Counties. View this publication on the Web at www.strom.clemson.edu/publications/ulbrich/home_rule.pdf The views presented here are not necessarily those of the Strom Thurmond Institute of Government and Public Affairs or of Clemson University. The Institute sponsors research and public service programs to enhance civic awareness of public policy issues and improve the quality of national, state, and local government. The Institute, a public service activity of Clemson University, is a nonprofit, nonpartisan, tax-exempt public policy research organization. -
Trials of a Tibetan Monk: the Case of Tenzin Delek
Human Rights Watch February 2004, Vol. 16, No. 1 (C) Trials of a Tibetan Monk: The Case of Tenzin Delek Map 1: Provinces and Autonomous Regions of the People’s Republic of China..............................1 Map2: Sichuan Province and Surrounding Areas....................................................................................2 Map 3: Southeastern Section of Kardze/Ganzi Tibetan Autonomous Prefecture............................3 I. Summary ....................................................................................................................................................5 Recommendations ...................................................................................................................................7 A Note on Methodology.........................................................................................................................8 II. Introduction...........................................................................................................................................10 Tenzin Delek ..........................................................................................................................................12 Lobsang Dondrup..................................................................................................................................14 Bombs......................................................................................................................................................15 III. Arrests...................................................................................................................................................17 -
Yunnan Provincial Highway Bureau
IPP740 REV World Bank-financed Yunnan Highway Assets management Project Public Disclosure Authorized Ethnic Minority Development Plan of the Yunnan Highway Assets Management Project Public Disclosure Authorized Public Disclosure Authorized Yunnan Provincial Highway Bureau July 2014 Public Disclosure Authorized EMDP of the Yunnan Highway Assets management Project Summary of the EMDP A. Introduction 1. According to the Feasibility Study Report and RF, the Project involves neither land acquisition nor house demolition, and involves temporary land occupation only. This report aims to strengthen the development of ethnic minorities in the project area, and includes mitigation and benefit enhancing measures, and funding sources. The project area involves a number of ethnic minorities, including Yi, Hani and Lisu. B. Socioeconomic profile of ethnic minorities 2. Poverty and income: The Project involves 16 cities/prefectures in Yunnan Province. In 2013, there were 6.61 million poor population in Yunnan Province, which accounting for 17.54% of total population. In 2013, the per capita net income of rural residents in Yunnan Province was 6,141 yuan. 3. Gender Heads of households are usually men, reflecting the superior status of men. Both men and women do farm work, where men usually do more physically demanding farm work, such as fertilization, cultivation, pesticide application, watering, harvesting and transport, while women usually do housework or less physically demanding farm work, such as washing clothes, cooking, taking care of old people and children, feeding livestock, and field management. In Lijiang and Dali, Bai and Naxi women also do physically demanding labor, which is related to ethnic customs. Means of production are usually purchased by men, while daily necessities usually by women. -
Xinjiang Regional Road Improvement Project (Korla-Kuqa Section)-Qiemo
Ethnic Minority Development Plan Ethnic Minority Development Plan Document Stage: Final Project Number: 39655 September 2007 PRC: Xinjiang Regional Road Improvement Project (Korla-Kuqa Section) Prepared by Communication Construction Administration Bureau of Xinjiang Uigur Autonomous Region for the Asian Development Bank (ADB). The ethnic minority development plan is a document of the borrower. The views expressed herein do not necessarily represent those of ADB’s Board of Directors, Management, or staff, and may be preliminary in nature. Xinjiang Regional Road Improvement Project Qiemo County Local Roads Ethnic Minority Development Plan Communication Construction Administration Bureau of Xinjiang Uigur Autonomous Region March 2007 Ethnic Minority Development Plan Endorsement Letter of Ethnic Minority Development Plan Ministry of Communication and Ministry of Finance have approved Qiemo County Local Road Project which is financed by ADB. The project is planned to commence in 2007 and finish in 2010. According to the requirements of ADB, an EMDP for the project should be compiled in accordance with the Social Safeguards Guidelines of the ADB. Communication Construction Bureau of Xinjiang Uygur Autonomous Region, with the assistance of PPTA consultants finished this plan. This EMDP is a key planning document of the project, which is approved and monitored by the ADB. Communication Department of Xinjiang Uygur Autonomous Region authorizes Communication Construction Bureau of Xinjiang Uygur Autonomous Region to be responsible for the implementation of the project and compilation of the EMDP. Communication Construction Bureau of Xinjiang Uygur Autonomous Region has asked for the views on the draft of this EMDP from relevant bureaus, departments, governments of towns or townships, and communities and incorporated those views into the EMDP. -
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Advances in Social Science, Education and Humanities Research, volume 231 5th International Conference on Community Development (AMCA 2018) Indonesia’s Development Policy to Increase Prosperity of the People in the Border Area Sonny Sudiar Bambang Irawan Mulawarman University, Samarinda Mulawarman University, Samarinda [email protected] [email protected] Abstract. The main issue of this paper highlights the Border area is defined as an area that geographically development policy and prosperity of the people in and demographically adjoins with the borders of a the border area. The border area has always been the country. Scholars exploring the study of international sexiest issues to discuss, as it is identical as a lagging border have developed extensive literatures on the topics and isolated area. The collaboration between the which range from the issue of state’s sovereignty on the government and local communities to overcome those border area [4], the relations between border and problems is needed. In this case, development policy international cooperation [5], the construction of border becomes the key role in order to increase the quality both in physical infrastructure and in intangible of social life especially for the local people. The notion perception of people’s mind [6]-[7] of development has lost its significance due to the One of Indonesia’s most worrying borders is absence of ethics or moral dimension. Practically, the Indonesia-Malaysia border in North Kalimantan. The ethics make the development more meaningful for the problems ranged from high political issues such as entire human life and environment comprehensively. dispute borderlands, damage or missing demarcation Development is a necessity that must be done by every pillars to social and economic issues such as single government to make progress and change for undeveloped region, low or non-existing of basic the better life of the citizens. -
The Investigation of Executive Condition of Minority Regions’ Special
Jan. 2007, Volume 6, No.1 (Serial No.43) Chinese Business Review, ISSN1537-1506, USA The Investigation of Executive Condition of Minority Regions’ Special Education Policies: The Case of Du’an Autonomous County 1 2 TU Wen-jing , MEI Jin-ping (1. College of Management, Guangxi University for Nationalities, Nanning 530006, China; 2. School of Economics, Zhongnan University of Economics and Law, Wuhan 430073, China) Abstract: The unbalance development of education is a widespread problem around the world, and the most outstanding of it is the lag of the education development of minority regions. For the sake of developing the education of minority regions, the government adopted a lot of policies and measures, enacting special education policies is the important matter among them. The paper tries to take Du’an autonomous county, Guangxi autonomous region as a case to explore the problems in the executive condition of minority regions’ special education policies, and gives the suggestion for the government to accelerate the education development of minority regions. Key words: minority regions; special education policies; Du’an County The unbalance development of education is a widespread problem around the world, and the most outstanding of it is the lag of the education development of minority regions. On account of the poor environment, behindhand economic development and laggard education, in the market competition, minority regions are in a disadvantaged position, they always stick in the poor abyss, and the gap between the minority regions and other regions in the country is bigger and bigger. Developing the education of minority regions, and promoting their “soft resources’ to make up the lack of their “hard resources”, is the essential way to supply the gap. -
Studies on Ethnic Groups in China
Kolas&Thowsen, Margins 1/4/05 4:10 PM Page i studies on ethnic groups in china Stevan Harrell, Editor Kolas&Thowsen, Margins 1/4/05 4:10 PM Page ii studies on ethnic groups in china Cultural Encounters on China’s Ethnic Frontiers Edited by Stevan Harrell Guest People: Hakka Identity in China and Abroad Edited by Nicole Constable Familiar Strangers: A History of Muslims in Northwest China Jonathan N. Lipman Lessons in Being Chinese: Minority Education and Ethnic Identity in Southwest China Mette Halskov Hansen Manchus and Han: Ethnic Relations and Political Power in Late Qing and Early Republican China, 1861–1928 Edward J. M. Rhoads Ways of Being Ethnic in Southwest China Stevan Harrell Governing China’s Multiethnic Frontiers Edited by Morris Rossabi On the Margins of Tibet: Cultural Survival on the Sino-Tibetan Frontier Åshild Kolås and Monika P. Thowsen Kolas&Thowsen, Margins 1/4/05 4:10 PM Page iii ON THE MARGINS OF TIBET Cultural Survival on the Sino-Tibetan Frontier Åshild Kolås and Monika P. Thowsen UNIVERSITY OF WASHINGTON PRESS Seattle and London Kolas&Thowsen, Margins 1/7/05 12:47 PM Page iv this publication was supported in part by the donald r. ellegood international publications endowment. Copyright © 2005 by the University of Washington Press Printed in United States of America Designed by Pamela Canell 12 11 10 09 08 07 06 05 5 4 3 2 1 All rights reserved. No part of this publication may be repro- duced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any infor- mation storage or retrieval system, without permission in writ- ing from the publisher. -
Speech by Vice-Governor of the People's Government of Yunnan
Ladies and gentlemen, I am from Yunnan Province, People’s Republic of China. I am Vice-Governor of the People’s Government of Yunnan Province. At the same time, I am also an organizer, participant, promoter and witness to HIV/AIDS prevention and care in Yunnan Province, having worked on HIV/AIDS control for 11 years. I would like to extend my great gratitude to UNAIDS and H.E. Mr. Sidibé for inviting me and my colleagues to be here and to have the opportunity to participate in this Board meeting and to share our experiences on HIV/AIDS prevention and control. As we all know, HIV/AIDS is still one of the most important public health issues in the world. It is also the common challenge and responsibility of all governments. In Yunnan Province of the People’s Republic of China, HIV/AIDS prevention and control is an important task. Yunnan Province is located in the southwestern tip of China and has a population of 47 million. There are 25 ethnic minority groups in Yunnan Province, which comprise 33% of the total population. Yunnan Province covers a land area of 394,000 square kilometers and is bordered with Myanmar, Laos and Viet Nam. It shares a 4060-kilometre border with these three countries and is in the vicinity of the Golden Triangle. Yunnan Province is one of the areas worst affected by drug trafficking. It is also one of the most important areas for HIV/AIDS prevention and control in China. By October 2016, 93,437 people had been diagnosed and reported to be living with HIV, which is 14% of the total cases in China. -
Dataset Description
Dataset Description Each GB code in the database consists of six digits. The first two digits represent the province, the second two the prefecture, and the third two the county. Province, prefectural, and county codings are contained in the linked document, Province codings. Because GB codes do not exist for every administrative unit that existed in the life of the database, it was necessary to create codes in certain circumstances. The construction of the database and information on assignment of values is described in the linked document, Procedures used in the creating the GB database. The dataset consists of ten fields for each record (see variable codes for a description of coding scheme): FIELD DESCRIPTION FORMAT ----------------------------------------------------------------------------------------------------------------------------------------- C-gbcode GB code integer C-source Source of code text N-pinyin Romanized name in Pinyin text N-local Romanized name using some non-Chinese pronunciations text N-hanzi Name in Chinese characters text H Hierarchical position of unit (county-level) integer A Administrative status of unit integer change Configuration of changes text P Hierarchical position of unit (prefecture-level) integer fromdate First day the coded configuration was in effect 8 digits in yyyymmdd todate Last day the coded configuration was in effect 8 digits in yyyymmdd NOTES Details regarding special circumstances text (255 characters) Files and Formats gbcodes1.mdb Microsoft Access Version 2.0 with user interface that allows to search on specific names or codes and also automatically create provincial and/or temporal subsets of the full 1982-1994 GB Codes database. The current version requires Microsoft Access 2.0 or higher to run.