PRMT8 Antibody Cat. No.: 56-275

PRMT8 Antibody

Western blot analysis of PRMT8 using rabbit polyclonal PRMT8 Antibody using 293 cell lysates (2 Western blot analysis of PRMT8 Antibody in K562 cell line lysates (35ug/lane) ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2).

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse

This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.

TESTED APPLICATIONS: WB

October 1, 2021 1 https://www.prosci-inc.com/prmt8-antibody-56-275.html APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 45 kDa WEIGHT:

Properties

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: PRMT8

Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein ALTERNATE NAMES: methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4

ACCESSION NO.: Q9NR22

PROTEIN GI NO.: 88983969

GENE ID: 56341

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N- methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of BACKGROUND: arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.

REFERENCES: 1) Lee,J., J. Biol. Chem. 280 (38), 32890-32896 (2005)

October 1, 2021 2 https://www.prosci-inc.com/prmt8-antibody-56-275.html ANTIBODIES FOR RESEARCH USE ONLY.

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