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OCal 5034-2 Page 1 of 2 List of Materials Prohibited for Use in OCal Cannabis Production This list is provided for reference purposes and is not intended to be comprehensive. In addition to the materials identified below, any synthetic material that is not included at 7 CFR § 205.601 of the National List of Allowed and Prohibited Substances (National List) is prohibited for use in OCal cannabis production. The materials listed below are specifically prohibited on the National List at 7 CFR § 205.602, have been reviewed by a Federal agency and determined to be prohibited, or are no longer allowed for use in organic (and therefore OCal) crop production. Find more classification information in OCal 5033 Classification of Unique Materials, OCal 5033- 1 Decision Tree for Classification of Materials, OCal 5033-2 Definitions of Terms Used for Classification, OCal 5034 Classification of Materials for OCal Cannabis Production, and OCal 5034-1 List of Materials for Use in OCal Production. 1,4-Dimethylnaphthalene Dextrin 3-Decen-2-one Ethylene Glycol 6-Benzyladenine Exhaust Gas (Carbon Monoxide) Acetylated Lanolin Alcohol Glycerin Oleate Acrylic Acid Methyl Ester, Polymer with Glyphosate Acrylonitrile and 1,3-Butadiene Humic acid, treated with hydrogen peroxide Ammonium Nonanoate, except as (oxidized lignite) provided on in 7 CFR § 205.601 Indole-3-butyric Acid Arsenic Lead Salts Ash from Manure Burning Leather Meal Avermectin Lime Mud Basic Slag, agricultural slag Magnesium Dihydrogen Phosphite Biosolids Monohydrate Calcium Carbide Manganous Oxide, except as provided on in Calcium Oxide, fertilizer use 7 CFR § 205.601(j) Calcium Sulfate (synthetic form) Methyl Bromide Captan Methyl Laurate Chitosan Monocalcium Phosphate Copper Chromium Arsenate Nickel Salts, Synthetic Coumarone – indene resin Niter Cryolite Pelargonic Acid OCal 5034-2 List of Materials Prohibited for Use in OCal Cannabis Production, April 6, 2020 23, 2021 OCal 5034-2 Page 2 of 2 Pentaerythritol Monostearate Struvite (Magnesium Ammonium Pentaerythritol Tetrastearate Phosphate) Piperonyl Butoxide Strychnine Propylene glycol monolaurate (PGML) Sulfuric Acid, except as provided on in 7 Polyoxin D Zinc Salt CFR §205.601(j) Potassium Sulfate (synthetic form) Tall Oil Propane, for underground rodent control Tetracycline Sewage Sludge Tetrahydrofufuryl Alcohol Sodium Chlorate Thiram Sodium Fluoaluminate Tobacco Dust (Nicotine Sulfate) Sodium Fluoride Triple Phosphate Sodium Lauryl Sulfate (SLS) Urea Sodium Propionate Streptomycin Note: Substances classified as EPA List 4, Inerts of Minimal Concern, may be permitted in pesticide products under section 7 CFR 205.601 (m). Certified operations should receive approval from their certifying agents before using pesticide products that contain these substances. OCal 5034-2 List of Materials Prohibited for Use in OCal Cannabis Production, April 6, 2020 23, 2021 .

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Prohibited Materials for Organic Crop Production
United States Department of Agriculture 1400 Independence Avenue SW. NOP 5034-2 Agricultural Marketing Service Room 2646-South Building Effective Date: December 2, 2016 National Organic Program Washington, DC 20250 Page 1 of 2 Guidance Appendix of Prohibited Materials for Organic Crop Production This list is provided for reference purposes and is not intended to be comprehensive. In addition to the materials identified below, any synthetic material that is not included at section 205.601 of the National List is prohibited for crop production. The materials listed below have been specifically prohibited on the National List at section 205.602, have been petitioned and reviewed by National Organic Standards Board and not recommended for addition to the National list, have expired from the National List, and/or have been reviewed by a Federal agency and determined to be prohibited for organic crop production. 1,4-Dimethylnaphthalene Manganous Oxide, except as provided on 3-Decen-2-one § 205.601(j) 6-Benzyladenine Methyl Bromide Acetylated Lanolin Alcohol Methyl Laurate Acrylic Acid Methyl Ester, Polymer with Monocalcium Phosphate Acrylonitrile and 1,3-Butadiene Nickel Salts, Synthetic Ammonium Nonanoate, except as provided Niter on § 205.601 Pelargonic Acid Arsenic Pentaerythritol Monostearate Ash from Manure Burning Pentaerythritol Tetrastearate Avermectin Piperonyl Butoxide Basic Slag, agricultural slag Propylene glycol monolaurate (PGML) Biosolids Polyoxin D Zinc Salt Calcium Carbide Potassium Sulfate (synthetic form) Calcium Oxide, fertilizer
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Nonanoic Acid Product-Type 2 (Disinfectants and Algaecides Not Intended for Direct Application to Humans Or Animals) September 2013 Austria
Regulation (EU) n°528/2012 concerning the making available on the market and use of biocidal products Evaluation of active substances Assessment Report Modification of the conditions of approval Nonanoic acid Product-type 2 (Disinfectants and algaecides not intended for direct application to humans or animals) September 2013 Austria Nonanoic acid Product-type 10 2013 Nonanoic acid (PT 2) Assessment report Finalised in the Standing Committee on Biocidal Products at its meeting on 27 September 2013 CONTENTS 1. STATEMENT OF SUBJECT MATTER AND PURPOSE ....................................... 4 1.1. Principle of evaluation ...................................................................................... 4 1.2. Purpose of the assessment ................................................................................. 4 1.3. Procedure followed ........................................................................................... 5 2. OVERALL SUMMARY AND CONCLUSIONS ...................................................... 7 2.1. Presentation of the Active Substance ................................................................ 7 2.1.1. Identity, Physico-Chemical Properties & Methods of Analysis ........ 7 2.1.2. Intended Uses and Efficacy ................................................................. 8 2.1.3. Classification and Labelling of the active substance Nonanoic acid .. 9 2.1.4. Classification and labelling of the biocidal product NEU 1170 H.... 12 2.2. Summary of the Risk Assessment ..................................................................
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Fatty Acids As Essential Adjuvants to Treat Various Ailments and Their Role in Drug Delivery: a Review
Nutrition 65 (2019) 138À157 Contents lists available at ScienceDirect Nutrition journal homepage: www.nutritionjrnl.com Review article Fatty acids as essential adjuvants to treat various ailments and their role in drug delivery: A review Aakash Katdare B. Pharm, MS. Pharm, Shreya Thakkar B. Pharm, M. Pharm, Shivshankar Dhepale B. Pharm, MS. Pharm, Dignesh Khunt B. Pharm, M. Pharm, Manju Misra B. Pharm, M. Pharm, Ph.D. * Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Ahmedabad, India ARTICLE INFO ABSTRACT Article History: Since the discovery of fatty acids, a niche has been carved for their vital role as adjuvants in drug delivery and Received 23 May 2018 as treatment for various diseases. The literature has repeatedly described the essential role of various fatty Received in revised form 1 February 2019 acids in treating a wide range of diseases and disorders, from central nervous system diseases to wound heal- Accepted 20 March 2019 ing. The use of fatty acids has expanded to many horizons and in recent decades they have gained impor- tance as drug delivery adjuvants in addition to their auxiliary beneﬁts in treating various diseases. Although Keywords: fatty acids aid in solving both formulation-based and therapeutic challenges to our knowledge, they have Polyunsaturated FA never been viewed as dual agents in modern scientiﬁc literature. The aim of this review was to provide this FA Lipids perspective and combine the very discreet literature about fatty acids, which includes their role as therapeu- Oils tic adjuvants and drug delivery agents. It gives insights on the use of fatty acids in treating the diseases of the Penetration enhancers eye, skin, central nervous system, viral diseases, and so on.
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CLH Report for Nonanoic Acid
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Fatty Acid Analysis by HPLC
Fatty Acid Analysis by HPLC Technical Note Current interest in fatty acids and trans-fatty acids in food materials has been increasing. Fatty acid is an organic acid found in fats, oils, and lipids. It can be classified according to chaing length, short chain (2-4 carbons), middle chain (5-10 carbons), and long chain (more than 11 carbons). Although gas chromatography is the predominant technique used for fatty acid analysis, high-performance liquid chromatography (HPLC) plays an important role in applications such as the geometrical isomer separation. By using both HPLC and GC, a better fatty acid profile can be obtained. High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC) COSMOSIL C18 COSMOSIL Cholester Free fatty acids Short fatty acids Good (HILIC) Poor Middle and long fatty acids Excellent Poor Fatty acid ester Short fatty acids Fair Poor Middle and long fatty acids Good Excellent Position or geometrical isomers of unsaturated fatty acids Fair Good Excellent Fair High sensitive analysis Excellent [labeling] Excellent Preparative separation Excellent Poor Lipids composed of complex fatty acid mixture Using both HPLC and GC to achieve better fatty acid profiling (*1) *1: Wakako Tsuzuki and Kaori Ushida, “Preparative Separation of cis- and trans- Isomers of Unsaturated Fatty Acid Methyl Esters Contained in Edible Oils by Reversed-Phase High-Performance Liquid Chromatography” Lipids (2009) 44: 373-379 1. Unsaturated Fatty Acid Analyses by HPLC (1) Geometrical Isomer Separations (cis/trans) Geometrical isomers (cis/trans) are difficult to separate by a C18 column due to their similar hydrophobicity. COSMOSIL Cholest- er column can achieve better separation due to higher molecular-shape selectivity.
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Alternatives to Glyphosate © 2018 Bio-Integral Resource Center
VOLUME XXXII, NUMBER 1-4, SPECIAL ISSUE (PUBLISHED DECEMBER 2018) Drawing courtesy Diane Kuhn Alternatives to Glyphosate © 2018 Bio-Integral Resource Center. All rights reserved. ISSN 8756-7881 Common Sense Pest Control XXXII(1-4) Special Issue 2018 2 Box 7414, Berkeley, CA 94707 Least-Toxic Photo courtesy Pharm Solutions Herbicides By William Quarles About 280 million pounds of glyphosate are applied each year, nearly a pound for each person in the U.S. Much of it is applied to genetically modified crops, but it is also used for weed control in urban and subur- ban landscapes, home lawns, golf courses, and schools (USGS 2015; Duke and Powles 2009). Amounts applied have increased five-fold since 1998, causing the EPA to increase residues allowed on food items such as soybeans. Systemic glyphosate cannot be Concentrated vinegar is corrosive, and personal washed off, and residues cannot be destroyed by cooking protection must be used. Residuals degrade quickly (Kruger et al. 2014; EFSA 2009). There is widespread to carbon dioxide and water. contamination of breakfast cereal, wine, and other com- modities. Glyphosate has been found in the bodies of 93% of people tested in the U.S. (Detox 2016). A study of Least-Toxic Herbicides senior citizens showed urinary concentrations of gly- Herbicides are either pre-emergent or post-emergent. phosate increased about 6-fold between 1999 and 2016 Corn gluten meal is the only pre-emergent least-toxic (Mills et al. 2017). herbicide (Quarles 1999; Quarles 2001). Post-emergent According to the International Agency for Research on products currently available are broad-spectrum contact Cancer (IARC), glyphosate is a probable human carcin- herbicides that kill weeds by desiccation or oxidation.
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Exploring Alternative Methods for Vegetation Control and Maintenance Along Roadsides
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BLUE BOOK 1 Pelargonic Acid CIR EXPERT PANEL MEETING JUNE
BLUE BOOK 1 Pelargonic Acid CIR EXPERT PANEL MEETING JUNE 28-29, 2010 CIR Panel Book Page 1 CIR History of: Pelargonic Acid and its Esters A scientific literature review (SLR) on this group of ingredients was announced on September 25, 2009. During the 60-day comment period on the SLR, industry data on cetearyl isononanoate and isononyl nonanoate were received. Most of the data are on chemical and physical properties of these ingredients, and only the conclusions for the following studies were also received: acute oral toxicity (cetearyl isononanoate – Tegosoft CI), skin irritation (cetearyl isononanoate – Tegosoft CI), acute oral toxicity (isononyl isononanoate – Tegosoft INI), skin irritation (isononyl isononanoate – Tegosoft INI), and ocular irritation (isononyl isononanoate – Tegosoft INI). These data have been incorporated. The following data on pelargonic acid, a registered herbicide, have been requested from the Environmental Protection Agency (EPA) and will be incorporated: acute inhalation, oral, and dermal toxicity data; ocular irritation, skin irritation, and skin sensitization data; and genotoxicity, reproductive toxicity, and carcinogenicity data. 1st Review, Belsito and Marks Teams/Panel: December 7-8, 2009 An insufficient data announcement with the following data requests was issued: (1) potential for dermal sensitization and irritation at current use concentrations (a human repeated insult patch test protocol is recommended) for isodecyl isononanoate (used at 80%) as a representative ester (available irritation/sensitization data on other ingredients also would be useful), (2) UV absorption data for pelargonic acid and isodecyl isononanoate as a representative acid and ester, respectively (such data on other ingredients listed in the safety assessment also would be useful), and (3) metabolic fates of isononanoic acid and isodecanol as representative constituent fatty acid and alcohols that would be produced after ester linkage cleavage.
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Octanoic Acid
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Efficacy of Natural Fatty Acid Based Herbicides on Mixed Weed Stands
28. Deutsche Arbeitsbesprechung über Fragen der Unkrautbiologie und -bekämpfung, 27.02. – 01.03.2018 in Braunschweig Efficacy of natural fatty acid based herbicides on mixed weed stands Wirksamkeit von natürlichen, auf Fettsäuren basierten Herbiziden auf Unkrautbestände Ivanna Crmaric1*, Martina Keller2**, Jürgen Krauss2, Nicolas Delabays1 1Institute Earth-Nature-Environment, Haute Ecole du Paysage, d’Ingénierie et d’Architecture (hepia), University of Applied Sciences and Arts of Western Switzerland, Geneva, Switzerland 2Vegetable-Production Extension, Plants and Plant Products, Agroscope, Wädenswil, Switzerland Corresponding authors, *[email protected]; **[email protected] DOI 10.5073/jka.2018.458.048 Abstract In the search for alternatives to synthetic herbicides we assessed the efficacy of 2 non-selective, natural products. The active substances were fatty acids: one herbicide containing pelargonic acid (C9) and the other containing caprylic (C8) and capric acids (C10). The aim of the study was to determine the dose required to achieve this range of efficacy (ED80) for weed stands with different canopy heights and densities. 2 trials were carried out. Weed stand height varied between 0.05 m (trial 2) and 0.25-0.35 m (trial 1). The herbicides were applied with a logsprayer on plots of 43.5 m2. Dose-response curves were calculated using green weed coverage determined by image analyses as response variable. The ED80 increased with increasing weed canopy height: from 0.9 to 1.7 of the standard dose (n) for the caprylic and capric acid containing product and from 0.7 n to 1.7 n for the pelargonic acid containing product. In conclusion, acceptable efficacies can be achieved if the herbicides are applied on young weed stages.
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Lipid Biomarkers of Lens Aging
Appl Biochem Biotechnol DOI 10.1007/s12010-012-9963-6 Lipid Biomarkers of Lens Aging Bimal Prasanna Mohanty & Soma Bhattacharjee & Prasenjit Paria & Arabinda Mahanty & Anil Prakash Sharma Received: 28 July 2012 /Accepted: 6 November 2012 # Springer Science+Business Media New York 2012 Abstract Lipids are important structural components of cell membranes and have profound effect on membrane fluidity. Lipid profiling and lipidomics have captured increased atten- tion due to the well-recognized roles of lipids in numerous human diseases. Investigating lipid profiles not only provides insights into the specific roles of lipid molecular species in health and diseases, but can also help in identifying potential preventive or therapeutic biomarkers. Cataract, the loss of transparency of eye lens, is a disease of protein aggregation. There are several factors contributing to the stability in protein conformation. Age-related changes in lipid composition could be a contributing factor for altered protein–lipid inter- action leading to protein aggregation and cataract. Keeping this in view, in the present study, fatty acid profiling from different age groups of lenses was carried out, using a freshwater catfish as the model. Total lipids were extracted from lenses of three different age groups of fishes (young, adult, and aged) and fatty acid methyl esters (FAME) were prepared and FAME analysis was carried out using gas chromatography–mass spectrometry. The results showed that three fatty acids viz. heneicosylic acid (C21), docosahexaenoic acid (C22:6), nervonic acid (C24:1) which were not present in the adult lens, appeared in the aged lens. On the other hand, eicosenoic acid (C20:1) present in the adult lens was found to be absent in the aged lens.
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Fatty Acid–Based Formulations for Wood Protection Against Mold and Sapstain
Fatty Acid–Based Formulations for Wood Protection against Mold and Sapstain Carol A. Clausen Robert D. Coleman Vina W. Yang Abstract Safer, highly effective biocides providing long-term protection of mold growth on wood-based materials is of interest to the wood protection industry. Moldicide formulations containing synergistic combinations of ingredients derived from natural sources are commonly recognized as a promising approach for the next generation of wood protectants. Although fatty acid (FA)–based chemistry has had some development in food sanitation and agriculture, little exploration relating to new mold inhibitors for wood and wood products has occurred. Low molecular weight, saturated monocarboxylic acids combined with selected adjuvants can effectively inhibit mold spore germination. Specifically, formulations containing valeric or pentanoic (C5), hexanoic or caproic (C6), heptanoic (C7), caprylic or octanoic (C8), pelargonic or nonanoic (C9), and/or decanoic or capric (C10) saturated acid demonstrated efficacy against mold growth for up to 12 weeks in the ASTM D4445 standard laboratory test for mold. Pressure-treated wood was more resistant to mold growth than wood dip treated with FA formulations. Finding a single synthetic or natural antimicrobial (100 ppm) destroyed spores of test fungi, whereas compound, either newly recognized or already registered, to dodecanoic acid (C12) was effective against brown-rot but inhibit the varied biological agents capable of colonizing not white-rot fungal spores. Schmidt’s ﬁndings suggested a wood and wood products is improbable. Likewise, biocide high degree of speciﬁcity dependent on the fatty acid resistance that occurs frequently and to varying degrees in concentration tested and test fungus. For example, all wood-inhabiting fungi increases the importance of cobio concentrations of hexadecanoic acid (C16) tested were cide interaction for successful wood protection.
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