DOCSLIB.ORG

Uncorrected Proof

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Uncorrected Proof : Pediatr Nephrol (2006) 21:1493–1635 # IPNA 2006 DOI 10.1007/s00467-006-0236-x ABSTRACTS UNCORRECTED PROOF 1494 Pediatr Nephrol (2006) 21:1493–1635 Pediatr Nephrol (2006) 21:1493–1635 1495 1496 Pediatr Nephrol (2006) 21:1493–1635 Pediatr Nephrol (2006) 21:1493–1635 1497 1498 Pediatr Nephrol (2006) 21:1493–1635 Pediatr Nephrol (2006) 21:1493–1635 1499 1500 Pediatr Nephrol (2006) 21:1493–1635 CONTENTS Oral Communication OC 11 Acute renal failure OC 1 Bladder disorders and voiding disturbances OC 12 - OC 13 Bone, growth and mineral metabolism OC 14 - OC 16 Chronic renal failure OC 5 - OC 6 Clinical nephrology OC 3 - OC 4 Glomerular disease OC 20 Hemodialysis OC 8 Hereditary renal disease OC 9 - OC 10 Hypertension OC 19 Peritoneal dialysis OC 17 - OC 18 Transplantation OC 7 Tubular and interstitial disorders OC 2 Urinary tract infection and VUR Oral Poster OP 31 - OP 33 Acute renal failure OP 11 Bladder disorders and voiding disturbances OP 55 Bone, growth and mineral metabolism OP 52 - OP 54 Chronic renal failure OP 12 - OP 17 Clinical nephrology OP 4 - OP 1O Experimental nephrology OP 41 - OP 49 Glomerular disease OP 38 - OP 40 Hereditary renal disease OP 51 Hypertension OP 1 - OP 3 Kidney development and cell biology OP 30 Obstructive urophathy OP 56 - OP 60 Peritoneal dialysis OP 21 - OP 29 Transplantation OP 34 - OP 35 Tubular and interstitial disorders OP 50 Urinary mineral abnormalities and urolithiasis OP 18 - OP 20 Urinary tract infection and VUR OP 36 - OP 37 Vasculitis and autoimmune related disease Pediatr Nephrol (2006) 21:1493–1635 1501 Poster Presentation PP 116 - PP 122 Acute renal failure PP 71 - PP 76 Bladder disorders and voiding disturbances PP 300 - PP 312 Bone, growth and mineral metabolism PP 313 - PP 342 Chronic renal failure PP 20 - PP 70 Clinical nephrology PP 10 Electrolyte and fluids PP 1 - PP 9 Experimental nephrology PP 343 - PP 393 Glomerular disease PP 102 - PP 115 Hemodialysis PP 159 - PP 196 Hereditary renal disease PP 277 - PP 299 Hypertension PP 11 - PP 16 Kidney development and cell biology PP 146 - PP 158 Obstructive urophathy PP 394 - PP 413 Peritoneal dialysis PP 17 - PP 19 Renal pysiology PP 197 - PP 246 Transplantation PP 123 - PP 145 Tubular and interstitial disorders PP 264 - PP 276 Urinary mineral abnormalities and urolithiasis PP 77 - PP 101 Urinary tract infection and VUR PP 247 - PP 263 Vasculitis and autoimmune related disease 1502 Pediatr Nephrol (2006) 21:1493–1635 COD. OC 1 COD. OC 2 ULTRASOUND BLADDER MEASUREMENTS CAN REPLACE Uneffectiveness of antibiotic prophylaxis in children with VUR. URODYNAMIC STUDY FOR DIAGNOSIS OF NON- Preliminary data from a controlled study. MONOSYMPTOMATIC NOCTURNAL ENURESIS Pennesi M, Peratoner L*, Giacomini A, Travan L, Bordugo A*, Minisini S Clinica L TAFURO, D DEL GAIZO, M VERNI`, L R IERVOLINO, R DEL GADO Pediatrica-IRCCS Burlo Garofolo-Trieste *Pediatria-Ospedale S.M. degli Angeli- DEPARTMENT OF PEDIATRICS, SECOND UNIVERSITY OF NAPLES , via L. De Pordenone Presenting Author: Pennesi Marco Crecchio , 80131 Napoli , Italy IRCCS Burlo Garofolo , via dell`Istria 65/1 , 34100 Trieste , Italy Purpose: we have compared urodynamic studies (UD) with ultrasound (US) measurements Background: Antibiotic prophylaxis in VUR affected children has never proved to be for diagnosis and follow-up of patients with Non-Monosymptomatic Nocturnal Enuresis effective in preventing recurrent urinary infections and secondary renal damage. (NMNE). Objective: To determine the efficacy of antibiotic prophylaxis in reducing UTI and Methods: 738 enuretics children with daytime voiding symptoms have been subordinated to secondary renal damage in VUR affected children. UD and to US bladder. The upper limits for US bladder wall thickness measurements are 3 Methods: 100 children diagnosed with grade 2 to 4 mono/bilateral VUR were enroled in the and 5 mm (full and empty bladder). 704 children (95,4%) have urodynamic signs of a study and have been randomized in two groups (prophylaxis versus non prophylaxis). overactive bladder and the US bladder wall measurements thickened. After a six-month At the entry of the study all children underwent to renal scan with dimercaptosuccinic acid antimuscarin treatment, we have repeated a new study with US and UD. Also after the first (DMSA) done at least 4 months after the UTI. cycle of therapy we have confirmed relation between urodynamic and ultrasound The children in the prophylaxis group were administered a two years antibiotic treatment. measurements. Basing on this evidence, we have modified diagnostic management of The DMSA and VCUG has been repeted after 2 years. patients with NMNE. In enuretics with daytime voiding symptoms and with significant US Results: 90 patients, (43 treated, 47 not treated) completed two years of follow up. measurement (bladder wall thickness >3mm and >5mm to full and empty bladder Total relapses has been 61 in 29 patients;36 in 16 children in the prophylaxis group vs 25 respectively) diagnostic management is concluded. This new protocol has been applied to among 13 children in the control group (0.3 relapses/year/patient). 296 patients with NMNE. Only 11 cases had a worsening in the DMSA scan: 2 border line at the entry became grade I After the first 6 months of therapy, a new US study has been performed in all patients. without UTI; 9 pathologic at the entry, 5 worsened without UTI and 4 with 1 or 2 UTI. Results: we found that 224 patients (75,7%) were full-responders with normal detrusor On the contrary in all the other cases with one or more UTI, we did not find any DMSA thickness; 54 patients (18,2%) were partial responders but without normalization of detrusor scan worsening. thickness; only 18 patients (6,1%) were classified as non-responders with a persistence of a Conclusions: thickened bladder wall. The UTI relapses have been more common n the children treated with antibiotic Conclusions:. According to our experience US, which is non-invasive, is especially useful prophylaxis. for diagnosis and follow-up of NMNE instead of UD, which is invasive and often traumatic There are no evidence of any relationship between the number of UTI relapses and the for children. progression of the renal damage. COD. OC 3 COD. OC 4 Glomerular sclerosis in kidneys with congenital nephrotic syndrome Nephrin is critical for the action of insulin on human glomerular (NPHS1) podocytes A-M Kuusniemi, A Kaukinen, A-T Lahdenkari, C Holmberg, R Karikoski, and H Jalanko RJM Coward , GI Welsh, A Koziell, J Tava ré, P W Mathieson, M A Saleem Hospital for Children and Adolescents and Biomedicum Helsinki, University of Helsinki, Bristol children`s hospital and Academic renal unit , Department of clinical sciences, North Finland Bristol, Southmead hospital, , BS10 5NB Bristol , UK , Biomedicum Helsinki, Haartmaninkatu 8, huone B526b , 00290 Helsinki , Finland The leading causes of albuminuria and end stage renal failure in the world are secondary to Congenital nephrotic syndrome of the Finnish type (NPHS1) is caused by mutations in the abnormalities in the production or cellular action of insulin including diabetes mellitus and NPHS1 gene encoding podocyte slit diaphragm protein nephrin. Children with NPHS1 have the hyperinsulinaemic metabolic syndrome. The human glomerular podocyte is a critical severe nephrotic syndrome from birth and are nephrectomized as infants. The removed cell for maintaining the filtration barrier of the kidney and preventing albuminuria. We have kidneys serve as a unique human material to analyze the development of renal failure in recently shown this cell to be insulin sensitive in respect to glucose uptake with kinetics kidneys with proteinuria. In this work, the histology and expression of glomerular cell similar to muscle cells1. We now show that the podocyte protein nephrin is essential for this markers and cytokines were studied in nephrectomized NPHS1 kidneys using light and process in podocytes. Unique conditionally immortalised podocytes from two different electron microscopy, immunohistochemistry, Western blotting, and cytokine array. The patients with nephrin mutations (natural human nephrin knockout models) are unresponsive results showed that mesangial sclerosis and obliteration of capillaries were evident in to insulin, knocking nephrin down with siRNA in wild type podocytes abrogates the insulin practically every glomerulus (1530 glomeruli studied). Severely damaged and well response and stable nephrin transfection of nephrin deficient podocytes rescues their insulin preserved nephrons were commonly found adjacent to each other. Several profibrotic response. Mechanistically the c terminus of nephrin is forming a protein-protein interaction mediators and enzymes were expressed in NPHS1 glomeruli. Few inflammatory cells with the vesicular SNARE protein VAMP2 (using yeast-2 hybrid studies and co- (NPHS1: 3.71.8 vs. controls: 1.10.2 cells/glomerular cross section (GCS); P<0.05) were immunoprecipitation) which functionally allows the GLUT1 and GLUT4 rich vesicles to detected in the glomeruli in spite of the increased expression of several chemokines. The fuse with the membrane of this cell. This work demonstrates a previously unsuspected role podocytes showed severe ultrastructural changes and hypertrophy but little hyperplasia of nephrin in vesicular docking and insulin responsiveness of podocytes. (MIB-1: 0.15/GCS in NPHS1 vs. 0.03/GCS in controls) or apoptosis (TUNEL: 0/GCS vs. 0.06/GCS). Moderate amounts (median 15.9 cells/ml vs. 0.7 cells/ml; P<0.05) of podocytes 1Coward et al. The Human Glomerular Podocyte Is a Novel Target for Insulin Action. were secreted into the urine of NPHS1 patients. No crescents, tip lesions or misdirected Diabetes 54:3095-3102. filtration into paraglomerular or paratubular space were detected. In conclusion, the results indicate that podocyte damage in NPHS1 kidneys lead to endocapillary lesions that progress to glomerular sclerosis. Glomerular tuft adhesions, crescent formation and misdirected filtration seem to play a minor role in this process.
Load more

Recommended publications
  • Long-Term Land Cover Changes in the Western Part of the Korean Demilitarized Zone
    land Article Long-Term Land Cover Changes in the Western Part of the Korean Demilitarized Zone Jae Hyun Kim 1,2,3 , Shinyeong Park 2, Seung Ho Kim 2 and Eun Ju Lee 3,* 1 Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea; [email protected] 2 DMZ Ecology Research Institute, Paju 10881, Korea; [email protected] (S.P.); [email protected] (S.H.K.) 3 School of Biological Sciences, Seoul National University, Seoul 08826, Korea * Correspondence: [email protected] Abstract: After the Korean War, human access to the Korean Demilitarized Zone (DMZ) was highly restricted. However, limited agricultural activity was allowed in the Civilian Control Zone (CCZ) surrounding the DMZ. In this study, land cover and vegetation changes in the western DMZ and CCZ from 1919 to 2017 were investigated. Coniferous forests were nearly completely destroyed during the war and were then converted to deciduous forests by ecological succession. Plains in the DMZ and CCZ areas showed different patterns of land cover changes. In the DMZ, pre-war rice paddies were gradually transformed into grasslands. These grasslands have not returned to forest, and this may be explained by wildfires set for military purposes or hydrological fluctuations in floodplains. Grasslands near the floodplains in the DMZ are highly valued for conservation as a rare land type. Most grasslands in the CCZ were converted back to rice paddies, consistent with their previous use. After the 1990s, ginseng cultivation in the CCZ increased. In addition, the landscape changes in the Korean DMZ and CCZ were affected by political circumstances between South and North Citation: Kim, J.H.; Park, S.; Kim, Korea.
    [Show full text]
  • Urge Syndrome and Urge Incontinence
    Arch Dis Child: first published as 10.1136/adc.64.11.1629 on 1 November 1989. Downloaded from Archives of Disease in Childhood, 1989, 64, 1629-1634 Personal practice Urge syndrome and urge incontinence J D VAN GOOL* AND G A DE JONGEt *Department of Paediatric Nephrology, University Hospital for Children and Youth, Utrecht, and tDepartment of Paediatrics, Vrije Universiteit, Amsterdam, The Netherlands Diurnal enuresis is still the common denominator tractions give rise to urgency and frequency early in for children who wet their pants. A closer look at the filling phase; in the other pattern, incomplete children with daytime wetting, however, shows that relaxation of striated urethral and pelvic floor there are two distinct categories: one with classic muscles interrupts actual voiding and causes a diurnal enuresis and normal bladder function, and staccato urinary flow. the other with urinary incontinence caused by an As these patterns of bladder sphincter over- 'urge syndrome', with bladder sphincter dysfunction, activity are detectable with urodynamic techniques and a conspiciously high incidence of recurrent we decided to investigate prospectively a selected urinary tract infections. group of children of school age whose presenting Overactivity of the detrusor and urethral muscles symptoms were persistent daytime wetting, urgency, is now an established cause for bladder sphincter and frequency. copyright. dysfunction in children, and it is usually associated with symptoms such as urgency, frequency, daytime Patients wetting, and urinary tract infections. 1-5 The symp- toms of dysfunction induced by overactivity have in Ninety girls and three boys with urge incontinence the past been blamed on either the detrusor muscle and recurrent urinary tract infections were studied.
    [Show full text]
  • Diagnosis and Management of Urinary Incontinence in Childhood
    Committee 9 Diagnosis and Management of Urinary Incontinence in Childhood Chairman S. TEKGUL (Turkey) Members R. JM NIJMAN (The Netherlands), P. H OEBEKE (Belgium), D. CANNING (USA), W.BOWER (Hong-Kong), A. VON GONTARD (Germany) 701 CONTENTS E. NEUROGENIC DETRUSOR A. INTRODUCTION SPHINCTER DYSFUNCTION B. EVALUATION IN CHILDREN F. SURGICAL MANAGEMENT WHO WET C. NOCTURNAL ENURESIS G. PSYCHOLOGICAL ASPECTS OF URINARY INCONTINENCE AND ENURESIS IN CHILDREN D. DAY AND NIGHTTIME INCONTINENCE 702 Diagnosis and Management of Urinary Incontinence in Childhood S. TEKGUL, R. JM NIJMAN, P. HOEBEKE, D. CANNING, W.BOWER, A. VON GONTARD In newborns the bladder has been traditionally described as “uninhibited”, and it has been assumed A. INTRODUCTION that micturition occurs automatically by a simple spinal cord reflex, with little or no mediation by the higher neural centres. However, studies have indicated that In this chapter the diagnostic and treatment modalities even in full-term foetuses and newborns, micturition of urinary incontinence in childhood will be discussed. is modulated by higher centres and the previous notion In order to understand the pathophysiology of the that voiding is spontaneous and mediated by a simple most frequently encountered problems in children the spinal reflex is an oversimplification [3]. Foetal normal development of bladder and sphincter control micturition seems to be a behavioural state-dependent will be discussed. event: intrauterine micturition is not randomly distributed between sleep and arousal, but occurs The underlying pathophysiology will be outlined and almost exclusively while the foetus is awake [3]. the specific investigations for children will be discussed. For general information on epidemiology and During the last trimester the intra-uterine urine urodynamic investigations the respective chapters production is much higher than in the postnatal period are to be consulted.
    [Show full text]
  • Gray03 May-Jun 2021 Gray01 Jan-Feb 2005.Qxd
    The Graybeards is the official publication of the Korean War Veterans Association (KWVA). It is published six times a year for members and private distribution. Subscriptions available for $30.00/year (see address below). MAILING ADDRESS FOR CHANGE OF ADDRESS: Administrative Assistant, P.O. Box 407, Charleston, IL 61920-0407. MAILING ADDRESS TO SUBMIT MATERIAL: Graybeards Editor, 2473 New Haven Circle, Sun City Center, FL 33573-7141. MAILING ADDRESS OF THE KWVA: P.O. Box 407, Charleston, IL 61920-0407. WEBSITE: http://www.kwva.us In loving memory of General Raymond Davis, our Life Honorary President, Deceased. We Honor Founder William T. Norris Editor Directors National Insurance Director Resolutions Committee Arthur G. Sharp Albert H. McCarthy Narce Caliva, Chairman 2473 New Haven Circle 15 Farnum St. Ray M. Kerstetter Sun City Center, FL 33573-7141 Term 2018-2021 Worcester, MA 01602 George E. Lawhon Ph: 813-614-1326 Narce Caliva Ph: 508-277-7300 (C) Tine Martin, Sr [email protected] 102 Killaney Ct [email protected] William J. McLaughlin Publisher Winchester, VA 22602-6796 National Legislative Director Tell America Committee Gerald W. Wadley, Ph.D. Ph: 540-545-8403 (H) Michele M. Bretz (See Directors) John R. McWaters, Chaiman [email protected] Finisterre Publishing Inc. National Legislative Assistant Larry C. Kinard, Asst. Chairman 3 Black Skimmer Ct Bruce R. 'Rocky' Harder Douglas W. Voss (Seee Sgt at Arms) Thomas E. Cacy Beaufort, SC 29907 1047 Portugal Dr Wilfred E. ‘Bill’ Lack [email protected] Stafford, VA 22554-2025 National Veterans Service Officer (VSO) Douglas M. Voss Richard “Rocky” Hernandez Sr.
    [Show full text]
  • 1Q 2019 Satisfaction Survey Report on the Youth Basic Income in Gyeonggi Province Basic Income Research Group(BIRG) August 2019
    POLICY BRIEF 1Q 2019 Satisfaction Survey Report on the Youth Basic Income in Gyeonggi Province Basic Income Research Group(BIRG) August 2019 Gyeonggi Research Institute POLICY BRIEF 1Q 2019 Satisfaction Survey Report on the Youth Basic Income in Gyeonggi Province Basic Income Research Group(BIRG) August 2019 Gyeonggi Research Institute Gyeonggi Research Institute Preface Recently, basic income is attracting people’s attention. This is due to the fact that it is being considered as a countermeasure for solving the social issue that our society is confronted with. However, controversies related to basic income and confrontations in stances still exist acute. Amidst it, there has been big and small experiments and pilot projects conducted to identify the effect of policies. The substantial number of cases is demonstrating extremely positive results. However, the limit lies in the fact that majority of them are small in scale or are not free from experimental conditions. On the contrary, instead of relying on experiments, Gyeonggi Province has been implementing a policy in full scale, that is a project on payment of youth basic income since April 2019. The youth basic income in Gyeonggi Province involves paying out KRW 1 million in the form of regional currency 4 times in a year individually to youths (age of 24) who has been residing in Gyeonggi Province for at least three consecutive years. Those eligible to receiving payment in a year are approximately 175,000 people, making this policy the second biggest in the world after the State of Alaska in USA in terms of scale. It is a case that is gaining international attention not only because of its scale but also because it is not an experiment and is an actual policy in implementation.
    [Show full text]
  • Adult Onset Nocturnal Enuresis
    0022-5347/01/1656-1914/0 ® THE JOURNAL OF UROLOGY Vol. 165, 1914–1917, June 2001 ® Copyright © 2001 by AMERICAN UROLOGICAL ASSOCIATION,INC. Printed in U.S.A. ADULT ONSET NOCTURNAL ENURESIS KYOKO SAKAMOTO AND JERRY G. BLAIVAS From the Department of Urology, Weil Medical College, Cornell University, Ithaca and Urocenter of New York, New York, New York, and Loyola University Medical Center, Maywood, Illinois ABSTRACT Purpose: We determined the etiology and prognostic significance of adult onset enuresis with absent daytime incontinence. Adult onset nocturnal enuresis unassociated with daytime incon- tinence is uncommon and there is a paucity of information about its incidence, significance, evaluation and treatment. We present a retrospective evaluation of this condition based on a database review of more than 3,000 consecutive patients referred for the evaluation of lower urinary tract symptoms. Materials and Methods: A database of 3,277 consecutive patients was searched for adult onset nocturnal enuresis. Patients with daytime incontinence were excluded from study. Evaluation consisted of history, physical examination, American Urological Association symptom score, voiding diary, uroflowmetry, estimation of post-void residual urine, video urodynamics, cystos- copy and radiographic evaluation of the upper tract. Results: Of 3,277 patients 8 (0.02%) had adult onset nocturnal enuresis without daytime incontinence as a primary complaint. Average American Urological Association symptom score was 12.6 (range 3 to 25), average maximum urine flow was 8.5 ml. per second (range 5 to 15) and average post-void residual urine volume was 350 ml. (range 50 to 489). All patients were men with severe prostatic or vesical neck obstruction as well as bilateral or unilateral hydronephrosis in 63%, a bladder diverticulum in 38%, vesicoureteral reflux in 50% and low bladder compliance in 50%.
    [Show full text]
  • The Prevalence of Enuresis and Its Association with Psychological Factors in Zahedan, a City of Iran
    Global Journal of Health Science; Vol. 8, No. 12; 2016 ISSN 1916-9736 E-ISSN 1916-9744 Published by Canadian Center of Science and Education The Prevalence of Enuresis and Its Association with Psychological Factors in Zahedan, a City of Iran Tahereh Boryri1, Noormohammad Noori2, Ghasem Miri Aliabad2 & Alireza Teimouri2 1 Pregnancy Health Research Center (PHRC), School of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran 2 Children and Adolescent Health Research Center (C & A. H. R. C.), Zahedan University of Medical Sciences (ZaUMS), Zahedan, Iran Correspondence: Alireza Teimouri, Children and Adolescent H. R. C., ZaUMS, Ali-ibn-Abu Talib Hospital, Zahedan, Iran. Tel: 98-91-5949-5312. E-mail: [email protected] Received: November 30, 2015 Accepted: February 28, 2016 Online Published: April 29, 2016 doi:10.5539/gjhs.v8n12p8 URL: http://dx.doi.org/10.5539/gjhs.v8n12p8 Abstract Introduction: Enuresis is a common problem with multiple causes in children. The aim of the present study was to establish the prevalence of enuresis among school population and its psychology and emotional associated factors. Methods: Clustering sampling was used to collect 2000 schoolchildren from city Zahedan. A research made questionnaire was applied as a tool for data collection. All parents were informed about the aims of study and signed the consent form. Statistical analyses were performed using SPSS 19.0. Odds ratio and χ2 tests were used with the level of significance as P=0.05. The power of the statistical analysis was 80 percent. Results: The prevalence of enuresis is 17.18% for boys and 11.82% for girls, and the overall prevalence is 14%.parental divorce, parental death, Physical punishment, living with step parents (parental divorce, computer game, watching horror movie and stress and domestic violence had significant correlation with enuresis.
    [Show full text]
  • Sustainability Report 2008 Sustainability Report 2008 About the Sustainability Report
    Sustainability Report 2008 Sustainability Report 2008 About the Sustainability Report Introduction and Structure Reporting Period Korea Land Corporation, since its establishment in 1975, has been committed to develop- This report illustrates our sustainability management activities and performance from ing the national economy and improving the public welfare. Today, we are doing our August 1 of 2006 to December 31 of 2007. Our first Sustainability Report was issued in best to take good care of our precious land resources which we share with our successive 2005, which describes our sustainability management for the calendar year 2004 and generations, keeping in mind the philosophy that we serve as a "National Land the <Sustainability Report 2008> is our third Sustainability Report which illustrates our Gardener". economic, environmental and social progress and our commitment to corporate social responsibility management. This report contains Our corporate strategies, systems, activities and performance in each of the three pillars of sustainability management: economy, environment and society. Scope and Limitations Data used in this report cover performance of all of our offices at home and abroad and Improvements from our Earlier Sustainability Report were collated as of December 31 of 2007 unless stated otherwise. Most data present This report responds to feedback from our external stakeholders including NGOs (the Center time-series trends of at least three years and denominated in Korean won. for Corporate Responsibility) and academia on our <Sustainability Report 2006>(published in December, 2006) in the following areas External Assurance -we made sure that this report specifies whether it satisfies reporting guidelines of the Global Reporting Initiative (GRI) and duly describes our commitment to sustainability management.
    [Show full text]
  • Urofacial Syndrome
    Case Reports Urofacial syndrome Hamdan H. Al-Hazmi, MD, Ayman A. Hammad, MD, Roman Jednak, MD, Mohamed T. El-Sherbiny, MD. ABSTRACT Case Report. Patient 1. A 12-year-old boy from Syria, whose parents were first cousins, and with The urofacial or Ochoa syndrome is a rare disease. 2 brothers and 4 healthy sisters. One brother had We report on 2 patients of middle-eastern origin, similarly been affected and died of uremia at 10 years of with a review of the current literature to further age. He was examined at 5 years of age with recurrent document the existence of this syndrome, and to febrile urinary tract infections, diurnal enuresis, and increase the general awareness of the classical facial bilateral vesicoureteral reflux. There was no history characteristics, which facilitates diagnosis. of constipation. Antireflux surgery was performed, Saudi Med J 2007; Vol. 28 (12): 1895-1897 however, it failed. Bilateral urinary diversion in the form of high cutaneous ureterostomies was eventually From the Division of Pediatric Urology (Al-Hazmi, Jednak, performed as a result of progressively deteriorating El-Sherbiny), Montreal Children’s Hospital, McGill University renal function. Physical examination revealed the Health Centre, Montreal, Canada, and the Urology and Nephrology Center (Hammad), Mansoura, Egypt. characteristic inversion of facial expression with smiling (Figure 1). The serum creatinine was normal. Received 24th January 2007. Accepted 30th April 2007. Both the neurological examination and MRI results of Address correspondence and reprint request to: Dr. Hamdan H. the lumbosacral spine were normal. Renal ultrasound Al-Hazmi, The Montreal Children’s Hospital, C529, 2300, rue Tupper, showed no hydronephrosis with normal size kidneys.
    [Show full text]
  • Isolation and Genetic Characterization of African Swine Fever Virus from Domestic Pig Farms in South Korea, 2019
    viruses Brief Report Isolation and Genetic Characterization of African Swine Fever Virus from Domestic Pig Farms in South Korea, 2019 Hyun-Joo Kim, Ki-Hyun Cho , Ji-Hyoung Ryu, Min-Kyung Jang, Ha-Gyeong Chae, Ji-Da Choi , Jin-Ju Nah, Yong-Joo Kim and Hae-Eun Kang * Animal and Plant Quarantine Agency, 177 Hyeoksin 8-ro, Gimcheon 39660, Korea; [email protected] (H.-J.K.); [email protected] (K.-H.C.); [email protected] (J.-H.R.); [email protected] (M.-K.J.); [email protected] (H.-G.C.); [email protected] (J.-D.C.); [email protected] (J.-J.N.); [email protected] (Y.-J.K.) * Correspondence: [email protected]; Tel.: +82-54-912-0884 Received: 7 October 2020; Accepted: 28 October 2020; Published: 30 October 2020 Abstract: On 17 September 2019, the first outbreak of African swine fever in a pig farm was confirmed in South Korea. By 9 October, 14 outbreaks of ASF in domestic pigs had been diagnosed in 4 cities/counties. We isolated viruses from all infected farms and performed genetic characterization. The phylogenetic analysis showed that all of fourteen ASFV isolates in South Korea belong to genotype II and serogroup 8. Additionally, all isolates had an intergenic region (IGR) II variant with additional tandem repeat sequences (TRSs) between the I73R and I329L genes and showed characteristics of central variable region (CVR) 1 of the B602L gene and IGR 1 of MGF 505 9R/10R genes. These are identical to the genetic characteristics of some European isolates and Chinese isolates. Keywords: African swine fever; virus isolation; genetic characterization; South Korea 1.
    [Show full text]
  • Factors Contributing to Residential Vacancy and Some Approaches to Management in Gyeonggi Province, Korea
    sustainability Article Factors Contributing to Residential Vacancy and Some Approaches to Management in Gyeonggi Province, Korea Jeehyun Nam 1, Jiae Han 2,* and Changho Lee 3,* 1 Department of Urban Planning & Housing Policy, Gyeonggi Research Institute, Gyeonggi-do 16207, Korea; [email protected] 2 Department of Architectural Engineering, Hongik University, Seoul 30016, Korea 3 Department of Geography Education (GIS Lab), Seoul national University, Seoul 08826, Korea * Correspondence: [email protected] (J.H.); [email protected] (C.L.); Tel.: +82-44-860-2021 (J.H.); +82-2-880-2557 (C.L.) Academic Editors: William D. Shuster, Audrey L. Mayer and Ahjond S. Garmestani Received: 13 February 2016; Accepted: 7 April 2016; Published: 13 April 2016 Abstract: With the decrease in the demand for large-scale apartments as a result of an aging society and a decrease in population, there has been an increase in vacant houses due to a supply that exceeds the projected demands. As a method of urban regeneration in rural areas and activation of citizen communities, the utilization of vacant houses has become one of the ways to promote a new lifestyle, active movement for citizen participation, and business model for long-term revitalization. This study aims to uncover and examine the major causes and factors behind the upswing in vacant houses. We investigated the current state of vacant houses, the recent policies concerning them, and the types of vacant houses in Korea’s Gyeonggi province. We then categorized and analyzed the causes of houses being vacant, their types, and the methods of utilizing them under different local conditions in order to understand the efficient processes and strategies for their utilization.
    [Show full text]
  • Enuresis As a Behavior Problem
    University of Nebraska Medical Center DigitalCommons@UNMC MD Theses Special Collections 5-1-1932 Enuresis as a behavior problem Howard D. Cogswell University of Nebraska Medical Center This manuscript is historical in nature and may not reflect current medical research and practice. Search PubMed for current research. Follow this and additional works at: https://digitalcommons.unmc.edu/mdtheses Part of the Medical Education Commons Recommended Citation Cogswell, Howard D., "Enuresis as a behavior problem" (1932). MD Theses. 193. https://digitalcommons.unmc.edu/mdtheses/193 This Thesis is brought to you for free and open access by the Special Collections at DigitalCommons@UNMC. It has been accepted for inclusion in MD Theses by an authorized administrator of DigitalCommons@UNMC. For more information, please contact [email protected]. TABLE OF CONTENTS SUBJECT I. INTRODUCTION 1 II. HISTORY 3 III. STATISTICAL SUMMARY 8 IV. PHYSIOLOGY 16 V. CLASSIFICATION 21 VI • ETIOLOGY AND TREATMENT 26 1. PHYSICAL OR ANATOMIC BASIS A. Theories 27 B. Treatment 38 2. FUNCTIONAL BASIS 41 A. Etiology (1) Oversensitive Nervous System 44 (2) Lack of Proper Tra.ining 51 B. Treatment (1) Prophylactic Treatment 62 (2) Active Treatment 65 VII. BIBLIOGRAPHY 76 - INTRODUCTION Enuresis has been defined by Davidson (21) as "a per­ sistenoe from early infanoy or the development during ohildhood of unintentional and unconsoious nocturnal or diurnal emptying of the bladder in the absence of demonstrable, organio, nervous or genito-urinary lesions.· Calvin (14) oalls this a symptom as does Ruhrah (58) wno adds tnat some under~Y1ng cause should be sought. There are few subjects ooncerningthe management of children on which there has been more written than enuresis.
    [Show full text]