Anti-WDR1 monoclonal antibody (DCABH-13995) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This encodes a containing 9 WD repeats. WD repeats are approximately 30- to 40- domains containing several conserved residues, mostly including a trp-asp at the C- terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of filaments. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen A synthetic peptide of human WDR1 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications Western Blot (Transfected lysate); ELISA

Size 1 ea

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name WDR1 WD repeat domain 1 [ Homo sapiens ]

Official Symbol WDR1

Synonyms WDR1; WD repeat domain 1; WD repeat-containing protein 1; actin-interacting protein 1; AIP1; NORI-1;

Entrez Gene ID 9948

Protein Refseq NP_005103

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved UniProt ID O75083

Chromosome Location 4p16.1

Pathway Hemostasis, organism-specific biosystem; Hypertrophy Model, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;

Function actin binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved