Anti-WDR1 monoclonal antibody (DCABH-13995) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40- amino acid domains containing several conserved residues, mostly including a trp-asp at the C- terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. Immunogen A synthetic peptide of human WDR1 is used for rabbit immunization. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A Conjugate Unconjugated Applications Western Blot (Transfected lysate); ELISA Size 1 ea Buffer In 1x PBS, pH 7.4 Preservative None Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. GENE INFORMATION Gene Name WDR1 WD repeat domain 1 [ Homo sapiens ] Official Symbol WDR1 Synonyms WDR1; WD repeat domain 1; WD repeat-containing protein 1; actin-interacting protein 1; AIP1; NORI-1; Entrez Gene ID 9948 Protein Refseq NP_005103 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved UniProt ID O75083 Chromosome Location 4p16.1 Pathway Hemostasis, organism-specific biosystem; Hypertrophy Model, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem; Function actin binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.