HNF6 Antibody (R31338)

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HNF6 Antibody (R31338) Catalog No. Formulation Size R31338 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug Bulk quote request Availability 1-3 business days Species Reactivity Human, Mouse, Rat Format Antigen affinity purified Clonality Polyclonal (rabbit origin) Isotype Rabbit IgG Purity Antigen affinity Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal UniProt Q9UBC0 Applications Western blot : 0.5-1ug/ml IHC (FFPE) : 0.5-1ug/ml IHC (Frozen) : 0.5-1ug/ml Immunocytochemistry : 0.5-1ug/ml Limitations This HNF6 antibody is available for research use only. Western blot testing of HNF6 antibody and Lane 1: rat liver; 2: mouse liver; 3: human HeLa cell lysate. Expected/observed size ~51KD IHC-P: HNF6 antibody testing of human liver cancer tissue ICC testing of HNF6 antibody and HCT116 cells IHC-F testing of rat liver tissue IHC-P testing of rat liver tissue Description One cut homeobox 1 (ONECUT1), also called Hepatocyte nuclear factor 6 (HNF6) is found strong expression in liver and lower expression in testis and skin. The gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Application Notes The stated application concentrations are suggested starting amounts. Titration of the HNF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity. Immunogen An amino acid sequence from the N-terminus of human ONECUT1/HNF6 (LGSIHNSQQGLPHYAHP) was used as the immunogen for this HNF6 antibody (100% homologous in human, mouse and rat). Storage After reconstitution, the HNF6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. Ordering: Phone:858.663.9055 | Fax:1.267.821.0800 | Email:[email protected] Copyright © NSJ Bioreagents. All rights reserved.

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Genome-Wide Association Study Identifies Eight Novel Loci
cells Article Genome-Wide Association Study Identiﬁes Eight Novel Loci for Susceptibility of Scrub Typhus and Highlights Immune-Related Signaling Pathways in Its Pathogenesis Yong-Chan Kim 1,2, Soriul Kim 3, Hee-Kwon Kim 4, Yi Lee 5 , Chol Shin 3,6, Chang-Seop Lee 7,8,* and Byung-Hoon Jeong 1,2,* 1 Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, Jeonbuk 54531, Korea; [email protected] 2 Department of Bioactive Material Sciences, Jeonbuk National University, Jeonju, Jeonbuk 54896, Korea 3 Institute for Human Genomic Study, College of Medicine, Korea University, Seoul 02841, Korea; [email protected] (S.K.); [email protected] (C.S.) 4 Molecular Imaging & Therapeutic Medicine Research Center, Department of Nuclear Medicine, Biomedical Research Institute, Jeonbuk National University Medical School and Hospital, Jeonju, Jeonbuk 54907, Korea; [email protected] 5 Department of Industrial Plant Science & Technology, Chungbuk National University, Chungju, Chungbuk 28644, Korea; [email protected] 6 Department of Internal Medicine, Division of Pulmonary Sleep and Critical Care Medicine, Korea University Ansan Hospital, Ansan 15355, Korea 7 Department of Internal Medicine, Research Institute of Clinical Medicine, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54907, Korea Citation: Kim, Y.-C.; Kim, S.; Kim, 8 Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Jeonbuk 54907, Korea H.-K.; Lee, Y.; Shin, C.; Lee, C.-S.; * Correspondence: [email protected] (C.-S.L.); [email protected] (B.-H.J.); Jeong, B.-H. Genome-Wide Tel.: +82-63-250-2391 (C.-S.L.); +82-63-900-4040 (B.-H.J.); Fax: +82-63-254-1609 (C.-S.L.); +82-63-900-4012 (B.-H.J.) Association Study Identiﬁes Eight Novel Loci for Susceptibility of Scrub Abstract: Scrub typhus is a fatal zoonotic disease caused by Orientia tsutsugamushi.
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Cis-Regulatory Analysis of Onecut1 Expression in Fate
bioRxiv preprint doi: https://doi.org/10.1101/854778; this version posted November 26, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. 1 Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells 2 3 Sruti Patoori1,2, Nathalie Jean-Charles2, Ariana Gopal2, Sacha Sulaiman2, Sneha Gopal2,3, Brian 4 Wang2, Benjamin Souferi2,4, Mark M. Emerson1,2,5 5 6 1 Biology PhD Program, The Graduate Center, The City University of New York, New York, NY, 7 10016 8 2 Department of Biology, The City College of New York, The City University of New York, New York, 9 NY, 10031 10 3 Present Address: Doctoral program in Department of Chemical and Biological Engineering, 11 Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy , 12 NY 12180 13 4 Present Address: Touro College of Osteopathic Medicine, New York, NY 10027 14 5 Biochemistry PhD Program, Graduate Center, City University of New York, NY 10016 15 16 *Corresponding author: [email protected] 17 18 Email addresses: 19 20 Sruti Patoori: [email protected] 21 Ariana Gopal: [email protected] 22 Sacha Sulaiman: [email protected] 23 Nathalie Jean-Charles: [email protected] 24 Sneha Gopal: [email protected] 25 Brian Wang: [email protected] 26 Benjamin Souferi: [email protected] 27 Mark Emerson: [email protected] 28 29 30 31 32 33 Running title: Retinal fate-restricted cis-regulatory elements 34 35 36 37 Keywords: retinal progenitor cells, multipotent, fate-restricted, cone photoreceptors, basic 38 helix-loop-helix, chicken, electroporation 39 40 41 42 43 1 bioRxiv preprint doi: https://doi.org/10.1101/854778; this version posted November 26, 2019.
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Anti-Human ONECUT1, Monoclonal Alternate Names: Hepatocyte Nuclear Factor 6
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