Pyramid Journal of Medicine 2019; volume 2:21 Aluminium phosphide within the first 24 hours are cardiac dys- poisoning: A case series at two rhythmias.4 Correspondence: Friezland Oswatch, The The exact mechanism for AlP poisoning Yellow Pharmacy, Box 193, Mankayane, hospitals in the Manzini is not fully understood. It is thought that it Manzini, Eswatini Region, Eswatini inhibits Cytochrome C Oxidase, however, Tel.: +268.78313718. that has only been shown in-vitro and is E-mail:
[email protected] 1 thought not to have such a significant effect Friezland Oswatch, 6 Key words: Weevil tablet, Aluminium 2 in humans. Others have suggested that for- Rodney H. Magwenya Phosphide poisoning, Eswatini, Poisoning in mation of highly reactive hydroxyl radicals 1 Africa. The Yellow Pharmacy, Mankayane, also leads to the fatal cellular respiratory Manzini, Eswatini; 2Outpatient 5 failure. Unfortunately, there is no known Acknowledgements: The authors would like Department, Mankayane Government antidote to aluminium phosphide poisoning, to thank the following who have contributed Hospital, Mankayane, Manzini, Eswatini however, several authors have suggested to the successful completion of this paper; supportive measures for treating patients Prof. Richard Heller for his expert critique, with mixed outcomes.7-11 Nompumelelo Nsibandze, Gcinekile Dlamini, Most reported cases in the literature are Khumbuzile Dlamini, Skhumbuzo Dlamini Abstract from India, Jordan, Morocco and Iran,6,9 (the data managers at both hospitals) for assisting with retrieval of the data, and others The absence of an antidote to with reported mortality rates well above 50%.4 However, not much information has who contributed to this document in one way Aluminium Phosphide (AlP) poisoning has or another but have not been mentioned here.