(12) Patent Application Publication (10) Pub. No.: US 2010/0105035 A1 Hashsham Et Al
US 20100105035A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2010/0105035 A1 Hashsham et al. (43) Pub. Date: Apr. 29, 2010 (54) ELECTROLUMINESCENT-BASED Related U.S. Application Data FLUORESCIENCE DETECTION DEVICE (60) Provisional application No. 60/860,702, filed on Nov. 22, 2006. (76) Inventors: Syed Anwar Hashsham, Okemos, MI (US); James M. Tiedje, Publication Classification Lansing, MI (US); Erdogan (51) Int. Cl. Gulari, Ann Arbor, MI (US); Dieter CI2O I/68 (2006.01) Tourlousse, East Lansing, MI (US); GOI. I./S8 (2006.01) Robert Stedtfeld, Lansing, MI C4DB 60/2 (2006.01) (US); Farhan Ahmad, East CI2M I/34 (2006.01) Lansing, MI (US); Gregoire CI2M I/240 (2006.01) Seyrig, Lansing, MI (US); Onnop CI2O I/04 (2006.01) Srivannavit, Ann Arbor, MI (US) CI2P 19/34 (2006.01) (52) U.S. Cl. ......... 435/6; 250/458.1506/39; 435/288.7; Correspondence Address: 250/459. 1; 435/34: 435/91.2 MEDLEN & CARROLL, LLP (57) ABSTRACT 101 HOWARD STREET, SUITE 350 The present invention provides compositions providing and SAN FRANCISCO, CA 94105 (US) methods using fluorescence detection device, comprising an electroluminescent light (EL) source, for measuring fluores (21) Appl. No.: 12/312,686 cence in biological samples. In particularly preferred embodiments, the present invention provides an economical, battery powered and Hand-held device for detecting fluores (22) PCT Filed: Nov. 21, 2007 cent light emitted from reporter molecules incorporated into DNA, RNA, proteins or other biological samples, such as a (86). PCT No.: PCT/US07/24290 fluorescence emitting biological sample on a microarray chip.
[Show full text]