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Society for Endocrinology BES 2011 11 –14 April 2011, Birmingham, UK Endocrine Abstracts Endocrine Abstracts April 2011 Volume 25 ISSN 1470-3947 (print) ISSN 1479-6848 (online) ISSN 2046-0368 (CD-ROM) Volume 25 Volume April 2011 Society for Endocrinology BES 2011 11 –14 April 2011, Birmingham, UK Online version available at 1470-3947(201104)25;1-Z www.endocrine-abstracts.org EEJEA_25-1_cover.inddJEA_25-1_cover.indd 1 22/17/11/17/11 77:59:31:59:31 PPMM Endocrine Abstracts (www.endocrine-abstracts.org) Endocrine Abstracts (ISSN 1470-3947) is published by Copyright © 2011 by BioScientifica Ltd. This publication BioScientifica, Euro House, 22 Apex Court, Woodlands, is copyright under the Berne Convention and the Bradley Stoke, Bristol BS32 4JT, UK. Universal Copyright convention. All rights reserved. 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EEJEA_25-1_cover.inddJEA_25-1_cover.indd 2 22/17/11/17/11 77:59:34:59:34 PPMM Volume 25 Endocrine Abstracts April 2011 Society for Endocrinology BES 2011 11–14 April 2011, Birmingham, UK Abstract Book EDITORS The abstracts submitted were marked by the Abstract Marking panel selected by the Programme Committee Programme Committee M Korbonits Programme Secretary K Chapman Programme Co-ordinator S Orme Programme Co-ordinator Members A Allahabadia M Druce K Meeran W Arlt C Duncan A Munir P Clayton J Johnston A Toogood E Davies V Kieffer J Wass W Dhillo C McArdle Abstract Marking Panel J Ahlquist Southend W Dhillo London A Lam Toronto, Canada R Quinton Newcastle upon Tyne F Ahmed Glasgow K Docherty Abderdeen G Lavery Birmingham S Razvi Gateshead B Allolio Wuerzburg, Germany W Drake London G Leese Dundee A Rees Cardiff R Amin London M Druce London A Levy Bristol E Scott Leeds R Andrew Edinburgh R Eastell Sheffield M Levy Leicester P Selby Manchester S Atkin Hull MEggoBirmingham N Martin London D Shapiro Glasgow S Aylwin London W Farrell Stoke C McArdle Bristol L Shepherd Birmingham L Bailey Liverpool D Flint Glasgow C McCabe Birmingham P Squires Warwick A Bates Birmingham R Fowkes London S McKenzie Glasgow C Stewart Cheshire K Boelaert Birmingham J Franklyn Birmingham A McNeilly Edinburgh N Taylor London P Bouloux London S Franks London J Miell London M Thomas London N Bridges London W Fraser Liverepool D Morganstein London J Tomlinson Birmingham J Burrin London M Grossman London D Morris Ipswich B Vaidya Plymouth K Chapman Edinburgh M Gurnell Cambridge J Morris Oxford M Vanderpump London T Cheetham Newcastle upon Tyne J Ham Cardiff N Morton Edinburgh B Walker Edinburgh P Clark Birmingham L Heisler Cambridge J Munday Portsmouth E Ward Leeds P Clayton Manchester M Holmes Edinburgh K Murphy London J Wass Oxford J Compston Cambridge T Howlett Leicester R Murray Leeds M Westwood Manchester M Cooper Birmingham S Hunter Belfast J Newell-Price Sheffield A Wheatman Sheffield SCoxTorquay A James Newcastle S Orme Leeds G Williams London M Dattani London R Jenkins Yorkshire S Peacey Bradford E Davies Glasgow K Jonas London S Pearce Newcastle J Davis Manchester N Karavitaki Oxford P Pickett Shrewsbury Society for Endocrinology BES 2011, Birmingham, UK CORPORATE SUPPORT The Society for Endocrinology would like to thank its Corporate Supporters, whose commitment is greatly appreciated. Platinum Supporters: BioScientifica Ltd Ipsen Ltd Pfizer Ltd Gold Supporters: Bayer Schering Pharma Ferring Pharmaceuticals Ltd Merck Serono Novartis Pharmaceuticals UK Ltd Novo Nordisk Ltd Silver Supporters: Almirall Ltd Amgen Ltd Eli Lilly and Company Ltd Sandoz Ltd The ‘Meet the Expert’ sessions and the ‘Clinical Management Workshops’ are generously supported by Clinical Endocrinology. Society for Endocrinology 22 Apex Court Tel: +44 (0) 1454 642210 Woodlands Fax: +44 (0) 1454 642222 Bradley Stoke E-mail: [email protected] Bristol BS32 4JT, UK Website: http://www.endocrinology.org Conference Secretariat BioScientifica Ltd Contact: Amanda Helm/Claire Arrigoni Euro House, 22 Apex Court Tel: +44 (0)1454 642268 Woodlands Fax: +44 (0)1454 642222 Bradley Stoke E-mail: [email protected] Bristol BS32 4JT, UK Website: http://www.bioscientifica.com Endocrine Abstracts (2011) Vol 25 Society for Endocrinology BES 2011, Birmingham, UK CONTENTS Society forEndocrinology BES 2011 PLENARYLECTURERS’ BIOGRAPHICAL NOTES PLENARYLECTURES Society for Endocrinology Dale Medal Lecture ........................................ PL1 Society for Endocrinology Hoffenberg International Medal Lecture ............................. PL2 Society for Endocrinology Transatlantic Medal Lecture ................................... PL3 Society for Endocrinology European Medal Lecture 2010 .................................. PL4 Society for Endocrinology European Medal Lecture 2011 .................................. PL5 Society for Endocrinology Medal Lecture ........................................... PL6 The British Thyroid Association Pitt Rivers Lecture ..................................... PL7 Clinical EndocrinologyTrust Visiting Professor Lecture ................................... PL8 Clinical EndocrinologyTrust Lecture ............................................. PL9 SYMPOSIA All youneed to know about the genetics of diabetes (types 1and 2and MODY) ................. S1.1–S1.4 Novelpathwaysand treatments in neuroendocrine tumours ............................ S2.1–S2.4 Fatendocrinology: disordersofadipose tissue and lipids important to the endocrinologist ............ S3.1–S3.4 Endocrine regulation of ageing ............................................ S4.1–S4.4 The novelrole of primarycilia in endocrine disease and obesity .......................... S5.1–S5.4 Novelapplication of thyroid hormone analogues: thyroid hormones, thinking outside the capsule ....... S6.1–S6.4 Eat, bond, reproduce –what the hypothalamus dictates .............................. S7.1–S7.4 Hormones and bone metabolism ........................................... S8.1–S8.4 Doping: performance enhancing substances in sportand their detection ..................... S9.1–S9.4 CLINICAL MANAGEMENT WORKSHOPS The management of difficult Graves’ disease ................................... CM1.1–CM1.4 Endocrine problems in pregnancy ......................................... CM2.1–CM2.4 Pituitaryradiotherapy: what are the options? .................................