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The Analytical Scientist APRIL 2014 # 15 the Analytical Scientist Upfront In My View Feature Solutions DNA aptamer-based sensors Don’t be a dedicated follower Is it time for a shake up in How to guarantee that beef for personalized medicine of funding fashion dioxin analysis? is pork-free 14 18 34 – 40 44 – 46 The Art of Simplicity George Whitesides’ 50 years of research experience has lead to a single, basic philosophy: keep it simple. 22 – 28 HiQ® The only word you need to remember in the world of specialty gases. High purity gases, ISO accredited calibration gas mixtures and precision gas control equipment for laboratories, research institutes and universities. http://hiq.linde-gas.com HiQ® Precision matters in everything we do. HiQ® is a registered trademark of The Linde Group. Linde AG Linde Gases Division, Seitnerstrasse 70, 82049 Pullach, Germany Phone +49.89.74 46-16 61, [email protected], http://hiq.linde-gas.com Online this Month Webinars Hot Topic Boost Pharmaceutical, Food, Diving into the Black Box Clinical and Toxicology Method (tas.txp.to/0414/blackbox) Development with Kinetex Biphenyl Core-Shell Technology. “Can the science be saved...? I agree completely with your comments Enjoy a brief overview of the and share your concerns. I have spent my benefits of core-shell technology entire career fighting for a role on the core results make sense based on our knowledge for HPLC, UHPLC, and LC/MS/ project team. Too often, analytical is called in of the project or study. MS, as well as practical advice and at the last minute when the project is in crisis It is person, not the box, who understands case studies. mode. Analyses are needed immediately what the box can and cannot do, and what and the appropriate methods have not been the results mean. April 30, 2014 – 11am EST developed. If analytical is part of the core – Frank, USA. team, these situations can be avoided. I have Sign up now: been fortunate in that a number of project Reformation of Education Programs for tas.txp.to/0314/pheno/web-reg team leaders have recognized the value of Analytcal Chemists... having analytical involved early on. These I totally agree with the points raised by projects have always gone much smoother. the [Wolfgang Lindner]. The analytical GPC Solutions – Optimizing your Analytical chemists must, as you suggest, data we obtain is just the window that helps Polymer Separations. educate themselves in the areas that they us to look into the ‘Black Box’. The inside are supporting. You do not need to become meaning of the data is very much linked with Gain an understanding of the an expert synthetic organic chemist, but the samples we analyze and the background important variables, learn how to you must have a basic understanding of the and/or matrix of the samples we collected. optimize those variables, and then chemistry involved. I have maintained for An analytical chemist should not only discover how to put the knowledge some time that the ‘chemistry’ has gone out know how to obtain the data and/or results into action to achieve reliable, of analytical chemistry. We have become so correctly but also how to interpret the data robust, high-resolution polymer infatuated with what the computer can do and/or results meaningfully. In this sense, an separations. that we forget to consider what is going on analytical chemist should be equipped with inside the ‘Black Box’. I have found it very the knowledge that relates with samples and May 13, 2014 – 3pm GMT frustrating over the years when I am trying the environment from where the sample to evaluate a new instrument and all that is comes from.” – James Xiong, China. Sign up now: discussed is the computer software and all tas.txp.to/0414/agilent/web-reg the manipulation that one can do with it. We Sign up online for free to seem to have forgotten that the computer is have your say: merely a collection of electronic components theanalyticalscientist.com/ and we are the ones that can determine if we subscribe are getting the expected results and if those Contents Why, how and where you read The Analytical Scientist Why? “… for its broad coverage of the life of analytical scientists” 16% Weekly “… to stay abreast of trends in analytical science” 19% newsletter– 10% “…to keep up to date with“… for new the and expert-written exciting research feature in articles”my area” 13% 15% “… to gain insight on professional development topics” 10% “… for the“… interviews for diverse with international key opinion opinions” leaders” 7%8% Website “… to gain insight on business topics” 4% – 19% 60 “… for something to do on my coffee break” 4% Outstanding 12% 50 Print 40 34% - minutes 30 than Less magazine– 34% How long for? 1-2 hours - 10% - hours 1-2 30 minutes - 1 hour - 54% - hour 1 - minutes 30 How do you rate us overall? 30 Decidedly patchy 1% How? 20 2% - hours 2 than More 50 PDFiPad or Average 13% – 37% Very good 74% 10 0 Once in a while 10 How often? – 8% Under Every other orissue less Scrutiny – 10% Level of content inside field Every Upfront 523 of you completed our issue reader survey, providing – 33% Too simplistic – 19% 1 us with a great deal of invaluable feedback – Most thank you! Here, we share Overly long and issues – 49% what you really think about complex – 4% About right - 77% The Analytical Scientist. USA – 29% UK – 11% Italy – 6% Upfront GermanySpain – 6% – 5% France – 4% India – 3% Reporting on research, Bewildered,Level ofbored content or outsidehappy? field The Netherlands – 4% Too simplistic – 9% SwitzerlandCanada – 3% – 2% personalities, policies and Elsewhere: 27% partnerships that are 12 shaping analytical science. About right – 84% Overly long and complex – 7% We welcome information on interesting collaborations or research that has really caught your eye, in a good or bad way. Email: 03 Online This Month [email protected] 10 Under Scrutiny 07 Editorial In My View What You Think 12 Macrofluidics Meets athologyP by Richard Gallagher 16 Juan Muñoz-Arnanz and 13 Setting the Scene With Odors Lourdes Ramos call for cheaper, faster, greener POP analysis 08 Contributors 14 Sense a Revolution 17 Should we be focusing on the effects of toxic cocktails? asks On The Cover Alberto Mantovani APRIL 2014 # 15 the Analytical Scientist The ultimate in simplicity: 18 Don’t become a victim of funding Upfront In My View Feature Solutions DNA aptamer-based sensors Don’t be a dedicated follower Is it time for a shake up in How to guarantee that beef for personalized medicine of funding fashion dioxin analysis? is pork-free 14 18 34 – 40 44 – 46 a paper-based diagnostic chip fashion, asserts Gary Hieftje the Mastering the Art of Simplicity Analytical Scientist George Whitesides’ 50 years of research experience has lead to a single, basic philosophy: keep it simple. from Diagnostics For All 22 – 28 (www.dfa.org). 20 Paul Petersen tells the story behind the dramatic name change for HET Instrument the Analytical Scientist the Analytical Scientist ISSUE 15 - APRIL 2014 Editor - Rich Whitworth [email protected] Editorial Director - Richard Gallagher [email protected] Scientific Director - Frank van Geel [email protected] Graphic Designer - Marc Bird [email protected] Managing Director - Andy Davies [email protected] Director of Operations - Tracey Peers [email protected] Publishing Director - Lee Noyes [email protected] Audience Development Manager - Tracey Nicholls [email protected] Digital Content Manager - David Roberts [email protected] Editor, Custom Publishing - Iestyn Armstrong-Smith [email protected] 22 Traffic and Administration Manger - Claire Lally [email protected] Editorial Advisory Board Monika Dittmann, Agilent Technologies, Germany Norman Dovichi, University of Notre Dame, USA Gary Hieftje, Indiana University, USA Emily Hilder, University of Tasmania, Australia Features 42 The Analytical Scientist × Ron Heeren, FOM-AMOLF, The Netherlands Agilent Technologies Tuulia Hyötyläinen, VTT Technical Research Centre of Finland 22 Mastering Simplicity Exploring Chinese Medicine Hans-Gerd Janssen, Unilever Research and Development, The Netherlands George Whitesides is no stranger with 2D-LC, by Oliver Schmitz Ian Jardine, Thermo Fisher Scientific, USA Robert Kennedy, University of Michigan, USA to the complexities of science but and Duxin Li Samuel Kounaves, Tufts University, USA Marcus Macht, Bruker Daltonik, Germany has chosen to forged a new path Luigi Mondello, University of Messina, Italy Peter Schoenmakers, that strives to keep science simple. University of Amsterdam, The Netherlands Robert Shellie, University of Tasmania, Australia Ben Smith, University of Florida, USA 34 Keeping Tabs on Dioxins Departments Frantisec Svec, University of California at Berkeley, USA Jean-François Focant puts Ian Wilson, Imperial College London, UK forward a case for a radical review 44 Solutions: Keeping it Kosher, Published by of the EU’s monitoring strategy by Ashley Sage Texere Publishing Limited, Booths Hall, for dioxins in food and feed. Booths Park, Chelford Road, Knutsford, Cheshire, WA16 8GS, UK General enquiries: www.texerepublishing.com [email protected] 47 Application Notes +44 (0) 1565 752883 Reports [email protected] 30 The Analytical Scientist × Distribution: Agilent Technologies Sitting Down With The Analytical Scientist is distributed worldwide through 21,000 printed copies to a targeted The Solution Evolution European mailing list of industry professionals 50 Gary Hieftje, and 58,750 electronic copies, including 27,583 Distinguished Professor and to North/South America, 26,509 to Europe, and 4,658 to the Rest of the World. Robert & Marjorie Mann Chair ISSN 2051-4077 of Chemistry, Indiana University Bloomington, USA. What You Think Editorial More than 500 of you provided us with your opinion on what we cover and how we cover it.
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