For Radiation Proctitis and Enteritis Hyperbaric Oxygen Therapy

ABBOTT NORTHWESTERN HOSPITAL Hyperbaric Oxygen Therapy

Clinical Benefits Mechanisms of Action Journal References Indications Hyperbaric Oxygen Therapy for Radiation Proctitis and Enteritis Hyperbaric Oxygen Therapy (HBOT) is an adjunctive therapy used to treat various conditions including radiation proctitis and enteritis. During treatment, patients breathe 100 percent oxygen while inside a treatment chamber that has been pressurized. This results in hyperoxygenation of blood and tissues which promotes angiogenesis, collagen synthesis, epithelization and improves leukocyte function. The course of a hyperbaric treatment typically lasts six–eight weeks (Monday–Friday) depending on the severity of the condition, as well as the patient’s individualized progress. Patients can expect each treatment to last approximately two hours. Near the 20th treatment, patients are evaluated to review their progress and consider the need for additional treatments. During treatment, patients can expect the following to ensure a pleasant experience: Patients may sleep, listen to the radio, or watch television or movies A hyperbaric technician is available chamber-side at all times Patients will be evaluated by a hyperbaric-trained physician prior to and following all treatments.

RADIATION PROCTITIS AND ENTERITIS INDICATIONS All patients with a history of pelvic radiation with documented radiation proctitis and enteritis are candidates for HBOT.

CONTACT INFORMATION: Abbott Northwestern Hospital Wound and Hyperbaric Clinic, W4300 800 E. 28th Street Minneapolis, MN 55407 612-863-9774 HYPERBARICHYPERBARICHYPERBARIC MEDICINE MEDICINE MEDICINE AT BEAUMONT AT BEAUMONT AT BEAUMONT HYPERBARICHYPERBARICHYPERBARIC OXYGEN OXYGEN OXYGENTHERAPY THERAPY THERAPY FOR FOROSTEORADIONECROSIS FOROSTEORADIONECROSIS OSTEORADIONECROSIS

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Am J BeaumontBeaumont HealthBeaumont CenterHealth CenterHealth Center Marx RE,Marx Ames RE,Marx JR. Ames The RE, JR.useClin Ames The ofOncol hyperbaric JR.use 2006The of hyperbaric useDec;29(6):588–92. oxygenof hyperbaric oxygen in bony oxygen in reconstruction bony in reconstruction bony ofreconstruction the irradiated of the irradiated of and the irradiatedtissue- and tissue- and tissue- HyperbaricHyperbaric MedicineHyperbaric Medicine Center Medicine Center Center deficientdeficient patient.deficient patient. J Oral patient.Dall’Era MaxillofacJ Oral MA,MaxillofacJ Oral HampsonSurg Maxillofac1982;40:412–420. Surg NB, 1Hsi982;40:412–420. Surg RA, 1Madsen982;40:412–420. B, Corman JM. Hyperbaric 4949 Coolidge4949 Coolidge4949 Hwy. Coolidge Hwy. Hwy. oxygen therapy for radiation-induced proctopathy in men treated for prostate Marx RE.Marx Part RE. II:Marx APart new RE. II: concept APart new II: conceptA in new the treatmentconcept in the treatment in of the osteoradionecrosis. treatment of osteoradionecrosis. of osteoradionecrosis. J Oral Maxillofac J Oral Maxillofac J Oral Surg Maxillofac Surg Surg Royal Oak,Royal Michigan Oak,Royal Michigan Oak, 48073 Michigan 48073 48073 cancer. J Urol 2006 Jul;176(1):87–90. 1983;41:351–357.1983;41:351–357.1983;41:351–357. Phone: 248.655.3101Phone: 248.655.3101Phone: 248.655.3101 Fax: 248.655.3148Fax: 248.655.3148Fax: 248.655.3148 Marx RE.Marx Osteoradionecrosis RE.Marx Osteoradionecrosis RE. Osteoradionecrosis of the jaws: of the Review jaws: of the Reviewand jaws: update. Reviewand update. HBO and Rev update. HBO1984;5:78–126. Rev HBO1984;5:78–126. Rev 1984;5:78–126. FURTHER INDICATIONS FOR HYPERBARIC OXYGEN THERAPY diabetic wounds soft tissue radionecrosis radiation cystitis chronic refractory osteomyelitis recipient site preparation for failed graft or flap preservation of compromised skin grafts and flaps osteoradionecrosis (treat and prevent) progressive necrotizing infection (necrotizing fasciitis, gas gangrene) acute traumatic ischemic injury

Hyperbaric Oxygen Therapy at Abbott Northwestern Hospital follows the accepted indications, standards and procedures recommended by the Undersea and Hyperbaric Medicine Society.

Wound and Hyperbaric Clinic, W4300 800 East 28th Street Minneapolis, MN 55407 612-863-9774 abbottnorthwestern.com