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PDL Class Review Announcement October 6, 2020

Drug Classes to be reviewed: Antibiotics, Inhaled; , Non-Oral; Antiemetics, Oral; Antiherpetic Agents, Oral; Antiherpetic Agents, Topical; Antihyperuricemics; Anti-Platelets; Antipsoriatics, Oral; Antipsoriatics, Topical; Epinephrine (Self-Injected) Products; Fluoroquinolones, Oral; H. Pylori Treatments; Hepatitis C Virus Treatments, Direct Acting Antivirals (DAAs); Hepatitis C Virus Treatments, Ribavirin Products; Methotrexate; Monoamine Oxidase Inhibitors (MAOIs); Newer Generation ; NSAIDs, Non-Oral; NSAIDs, Oral; Pancreatic Enzymes; Proton Pump Inhibitors; Pulmonary Arterial Hypertension (PAH) Therapies, Endothelin Antagonists; PAH Therapies, Guanylate Cyclase Stimulator (sGC); PAH Therapies, Phosphodiesterase Inhibitors; PAH Therapies, ; Targeted Immune Modulators; Antidepressants; and Other Migraine Treatments, Non-Oral; Triptans and Other Migraine Treatments, Oral; Ulcerative Colitis Agents, Oral; Ulcerative Colitis Agents, Rectal.

These drug classes will be reviewed at the October 6, 2020 P&T Committee meeting from 1‐5pm. The meeting will be held virtually. Dossiers and Supplemental Rebate offers are due to Magellan by September 8, 2020.

Please provide your public comments to Jessica Czechowski, Pharmacist Account Executive ([email protected]) no later than September 25, 2020 to ensure they may be included in the information supplied to the P&T Committee members. Please copy Brittany Schock, PDL Pharmacist ([email protected]) on all clinical information and public comment submissions.

ANTIBIOTICS, INHALED Brand Name Generic Name

Arikayce Amikacin liposomal vial

Bethkis Tobramycin ampule

Cayston Aztreonam

Kitabis Tobramycin Pak

Tobramycin nebulizer Pak

Tobi Tobramycin inhalation solution

Tobramycin inhalation solution

Tobi Podhaler Tobramycin inhalation ANTIEMETICS Brand Name Generic Name

Oral

Doxylamine 25 mg OTC

Granisetron tablet

Meclizine tablet

Prochlorperazine tablet

Promethazine , tablet

Pyridoxine 50mg, 100 mg tablet OTC

Akynzeo / capsule

Bonjesta ER /pyridoxine tablet

Diclegis Doxylamine/pyridoxine tablet

Doxylamine/pyridoxine tablet

Emend Aprepitant capsule, pack, tripack

Aprepitant capsule, tripack

Marinol capsule

Dronabinol capsule

Reglan tablet

Metoclopramide ODT, solution, tablet

Tigan capsule

Trimethobenzamide capsule

Varubi tablet

Zofran tablet

Ondansetron tablet, ODT, oral solution/

Zuplenz Ondansetron film

Non-Oral Compro suppository

Prochlorperazine suppository

Phenadoz suppository

Promethazine suppository

Sancuso patch

Sustol Granisetron

Transderm-Scop patch

Scopolamine patch

ANTIHERPETIC AGENTS Brand Name Generic Name

Oral

Famciclovir tablet

Sitavig Acyclovir buccal tablet

Valtrex Valacyclovir tablet

Valacyclovir tablet

Zovirax Acyclovir suspension

Acyclovir tablet, capsule, suspension

Topical

Denavir Penciclovir

Xerese Acyclovir/hydrocortisone cream

Zovirax Acyclovir ointment, cream

Acyclovir ointment, cream

ANTIHYPERURICEMICS Brand Name Generic Name

Probenecid tablet

Probenecid-Colchicine tablet

Colcrys Colchicine tablet

Colchicine tablet

Gloperba Colchicine solution

Mitigare Colchicine capsule

Colchicine capsule

Uloric Febuxostat tablet

Febuxostat tablet

Zyloprim Allopurinol tablet

Allopurinol tablet

ANTI-PLATELETS Brand Name Generic Name

Cilostazol tablet

Dipyridamole tablet

Pentoxifylline ER tablet

Aggrenox /dipyridamole capsule

Aspirin/dipyridamole capsule

Brilinta Tigacrelor tablet

Effient Prasugrel tablet

Prasugrel tablet

Plavix Clopidogrel tablet

Clopidogrel tablet Zontivity Vorapaxar tablet

ANTIPSORIATICS Brand Name Generic Name

Oral

Oxsoralen-Ultra Methoxsalen capsule

Methoxsalen capsule

Soriatane Acitretin capsule

Acitretin capsule

Topical

Dovonex Calcipotriene cream

Calcipotriene cream, ointment, solution

Duobrii Halobetasol/Tazarotene

Enstilar Calcipotriene/Betamethasone DP foam

Sorilux Calcipotriene foam

Taclonex Calcipotriene/Betamethasone DP ointment, suspension

Calcipotriene/Betamethasone DP ointment, suspension

Vectical Calcitriol ointment

Calcitriol ointment

EPINEPHRINE PRODUCTS, SELF-ADMINISTERED Brand Name Generic Name

Epinephrine auto-injector (generic Adrenaclick)

Epipen, Epipen Jr. Epinephrine auto-injector

Epinephrine auto-injector

Symjepi Epinephrine syringe Epinephrine syringe

FLUOROQUINOLONES (ORAL) Brand Name Generic Name

Ciprofloxacin ER tablet

Levofloxacin tablet, solution

Ofloxacin tablet

Avelox Moxifloxacin tablet

Moxifloxacin tablet

Baxdela Delafloxacin tablet

Cipro Ciprofloxacin tablet, suspension

Ciprofloxacin tablet, suspension

H. PYLORI TREATMENTS Brand Name Generic Name

Amoxicillin / lansoprazole / clarithromycin

HELIDAC Bismuth subsalicylate / metronidazole / tetracycline

OMECLAMOX-PAK Amoxicillin / omeprazole / clarithromycin

PYLERA Bismuth subcitrate / metronidazole / tetracycline

TALICIA Omeprazole / amoxicillin / rifabutin

HEPATITIS C VIRUS TREATMENTS Brand Name Generic Name

Direct Acting Antivirals (DAAs)

Epclusa Velpatasvir/Sofosbuvir tablet

Velpatasvir/Sofosbuvir tablet Harvoni Ledipasvir/ Sofosbuvir tablet

Ledipasvir/ Sofosbuvir tablet

Mavyret Glecaprevir/Pibrentasvir tablet

Sovaldi Sofosbuvir tablet

Viekira Pak Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir tablet

Vosevi Velpatasvir/Sofosbuvir/Voxilaprevir tablet

Zepatier Elbasvir/Grazoprevir tablet

Ribavirin Agents

Ribasphere Ribavirin capsule, dosepack, tablet

Ribavirin capsule, dosepack, tablet

METHOTREXATE Brand Name Generic Name

Oral

Trexall Methotrexate tablet

Methotrexate tablet

Xatmep Methotrexate oral solution

Non-Oral

Methotrexate Vial

Otrexup Methotrexate auto-injector

Rasuvo Methotrexate auto-injector

MONOAMINE OXIDASE INHIBITORS (MAOIS) Brand Name Generic Name

Emsam patch

Marplan tablet Nardil tablet

Phenelzine tablet

Parnate tablet

Tranylcypromine tablet

NEWER GENERATION ANTIDEPRESSANTS Brand Name Generic Name

Bupropion IR Tablet

Desvenlafaxine fumarate ER tablet

Duloxetine 40mg capsule (generic Irenka)

Fluvoxamine IR tablet, ER capsule

Nefazodone tablet

Trazodone tablet

Venlafaxine IR tablet, ER tablet

Aplenzin ER tablet

Celexa tablet

Citalopram solution, tablet

Cymbalta DR capsule

Duloxetine DR capsule

Drizalma Duloxetine sprinkle capsule

Effexor XR ER capsule

Venlafaxine ER capsule

Fetzima ER ER capsule, titration pak

Forfivo XL Bupropion XL tablet

Bupropion XL tablet

Lexapro tablet Escitalopram tablet, oral solution

Paxil tablet, oral suspension

Paroxetine tablet

Paxil CR Paroxetine CR tablet

Paroxetine CR/ER tablet

Pexeva Paroxetine mesylate tablet

Pristiq succinate ER tablet

Desvenlafaxine succinate ER tablet

Prozac pulvule

Fluoxetine capsule, DR capsule, oral solution

Remeron tablet, ODT Soltab

Mirtazapine tablet, ODT

Sarafem Fluoxetine tablet

Fluoxetine tablet

Trintellix tablet

Viibryd tablet, Starter Pack

Wellbutrin SR, XL Bupropion ER/SR, XL tablets

Bupropion ER/SR, XL tablets

Zoloft tablet, oral concentrate

Sertraline tablet, oral concentrate

NSAIDS Brand Name Generic Name

Oral

Diclofenac sodium DR/EC tablet, ER tablet

Diclofenac potassium tablet tablet

Etodolac capsule, tablet, ER tablet

Flurbiprofen tablet

Ibuprofen RX tablet, suspension

Indomethacin capsule, ER capsule

Ketoprofen capsule, ER capsule

Ketorolac tablet

Meclofenamate capsule

Mefenamic acid capsule

Nabumetone tablet

Naproxen tablet, DR tablet, EC tablet, ER tablet, suspension tablet

Tolmetin tablet, capsule

Anaprox DS sodium tablet

Naproxen sodium tablet

Arthrotec Diclofenac/ tablet

Diclofenac/misoprostol tablet

Celebrex capsule

Celecoxib capsule

Daypro tablet

Oxaprozin tablet

Duexis /famotidine tablet

Feldene capsule

Piroxicam capsule

Indocin Indomethacin suspension Mobic tablet

Meloxicam tablet, suspension

Nalfon capsule, tablet

Fenoprofen capsule, tablet

Naprelan CR Naproxen sodium CR tablet

Naproxen sodium CR tablet

Qmiiz Meloxicam ODT

Tivorbex Indomethacin capsule

Vimovo Naproxen/esomeprazole DR tablet

Naproxen/esomeprazole DR tablet

Vivlodex Meloxicam capsule

Zipsor Diclofenac capsule

Zorvolex Diclofenac capsule

Non-Oral

Diclofenac topical solution

Flector Diclofenac patch

Diclofenac patch

Licart Diclofenac patch

Pennsaid Diclofenac solution packet, pump

Sprix nasal solution

Ketorolac nasal solution

Voltaren Diclofenac

Diclofenac gel

PANCREATIC ENZYMES Brand Name Generic Name

Creon Lipase/Protease/Amylase

Pancreaze Lipase/Protease/Amylase

Pertzye Lipase/Protease/Amylase

Viokace Lipase/Protease/Amylase

Zenpep Lipase/Protease/Amylase

PROTON PUMP INHIBITORS Brand Name Generic Name

Esomeprazole DR 49.3mg capsule

Omeprazole DR capsule

Omeprazole DR tablet (OTC), ODT (OTC)

Aciphex Rabeprazole tablet, sprinkles

Rabeprazole tablet

Dexilant Dexlansoprazole capsule

Nexium Esomeprazole DR capsule, oral suspension packet

Esomeprazole DR capsule, oral suspension packet

Nexium 24HR (OTC) Esomeprazole DR capsule (OTC)

Esomeprazole DR capsule (OTC)

Prilosec DR Omeprazole suspension

Prevacid Lansoprazole DR capsule, ODT solutab, suspension

Lansoprazole DR capsule, ODT

Prevacid 24HR DR (OTC) Lansoprazole DR capsule (OTC)

Lansoprazole DR capsule (OTC)

Protonix DR Pantoprazole DR tablet, oral suspension packet Pantoprazole DR tablet

Zegerid Omeprazole/Na Bicarb capsule, oral suspension packet

Omeprazole/Na Bicarb capsule, oral suspension packet

PULMONARY ARTERIAL HYPERTENSION (Endothelin Antagonists) Brand Name Generic Name

Letairis tablet

Ambrisentan tablet

Opsumit tablet

Tracleer tablet, tablet for suspension

Bosentan tablet

PULMONARY ARTERIAL HYPERTENSION (Guanylate Cyclase Stimulator) Brand Name Generic Name

Adempas tablet

PULMONARY ARTERIAL HYPERTENSION (Phosphodiesterase Inhibitors) Brand Name Generic Name

Adcirca tablet

Alyq Tadalafil 20mg tablet

Tadalafil 20 mg tablet

Revatio tablet, oral suspension

Sildenafil tablet, oral suspension

PULMONARY ARTERIAL HYPERTENSION (Prostanoids) Brand Name Generic Name

Flolan Epoprostenol vial

Epoprostenol vial

Orenitram ER tablet

Remodulin Treprostinil vial

Treprostinil vial

Tyvaso Treprostinil inhalation solution

Uptravi Selexipag tablet, dosage pack

Veletri Epoprostenol vial

Ventavis inhalation solution

TARGETED IMMUNE MODULATORS Brand Name Generic Name

Actemra Tocilizumab SC syringe, Actpen

Arcalyst Rilonacept SC vial

Cimzia Certolizumab SC kit

Cosentyx Secukinumab SC pen, syringe

Enbrel Etanercept SC kit, mini cartridge, sureclick, syringe, vial

Humira Adalimumab SC syringe, pen, kit

Ilaris Canakinumab SC vial

Kevzara Sarilumab SC pen, syringe

Kineret Anakinra SC syringe

Olumiant Baricitinib oral tablet

Orencia Abatacept SC clickject, syringe

Otezla Apremilast oral tablet Rinvoq Upadacitinib ER oral tablet

Siliq Brodalumab SC syringe

Simponi Golimumab SC pen injector, syringe

Skyrizi Risankizumab-rzaa SC syringe

Stelara Ustekinumab SC syringe

Taltz Ixekizumab SC , syringe

Tremfya Guselkumab SC injector, syringe

Xeljanz Tofacitinib oral tablet

Xeljanz XR Tofacitinib ER oral tablet

TRICYCLIC ANTIDEPRESSANTS Brand Name Generic Name

Amitriptyline tablet

Amoxapine tablet

Doxepin capsule 10mg, 25mg, 50mg, 75mg, 100mg, 150mg, solution pamoate capsule

Maprotiline tablet

Protriptyline tablet

Anafranil capsule

Clomipramine capsule

Norpramin tablet

Desipramine tablet

Pamelor capsule

Nortriptyline capsule, solution

Surmontil capsule

Trimipramine capsule Tofranil Imipramine tablet

Imipramine tablet

TRIPTANS AND OTHER MIGRAINE AGENTS Brand Name Generic Name

Oral

Almotriptan tablet

Amerge Naratriptan tablet

Naratriptan tablet

Frova Frovatriptan tablet

Frovatriptan tablet

Imitrex Sumatriptan tablet

Sumatriptan tablet

Maxalt, Maxalt MLT tablets, ODT

Rizatriptan tablets, ODT

Relpax Eletriptan tablet

Eletriptan tablet

Reyvow Lasmitidan tablet

Treximet Sumatriptan/naproxen tablet

Sumatriptan/naproxen tablet

Zomig, Zomig ZMT Zolmitriptan tablet, ODT

Zolmitriptan tablet, ODT

Non-Oral

Imitrex Sumatriptan , cartridge, pen injector, syringe, vial, kit Sumatriptan nasal spray, cartridge, pen injector, syringe, vial, kit Onzentra Xsail Sumatriptan nasal powder

Tosymra Sumatriptan nasal spray

Zembrace Symtouch Sumatriptan SC auto-injector

Zomig Zolmitriptan nasal spray

ULCERATIVE COLITIS AGENTS Brand Name Generic Name

Oral

Apriso Mesalamine ER capsule

Mesalamine ER capsule

Asacol HD Mesalamine DR tablet

Mesalamine DR tablet

Azulfidine, Azulfidine Entab Sulfasalazine tablet, DR tablet

Sulfasalazine tablet, DR tablet

Colazal Balsalazide capsule

Balsalazide capsule

Delzicol Mesalamine DR capsule

Mesalamine DR capsule

Dipentum Olsalazine capsule

Lialda Mesalamine DR tablet

Mesalamine DR tablet

Pentasa Mesalamine capsule

Uceris Budesonide tablet

Budesonide tablet

Non-Oral Canasa Mesalamine suppository

Mesalamine suppository

Rowasa, SFRowasa Mesalamine , kit

Mesalamine enema, kit

Uceris Budesonide rectal foam