Kaposi's Sarcoma and Psoriasis in a Naïve HIV-Positive Patient
INFECT DIS TROP MED 2019; 5: E569 Kaposi’s Sarcoma and Psoriasis in a naïve HIV-positive patient: a case report F. D’Andrea1, A. Facciolà1, M. G. Coco1, C. Micali1, I. Paolucci2, D. Maranto2, M. R. Lo Presti Costantino2, D. Larnè1, P. Mondello2, G. F. Pellicanò3 1Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy 2Unit of Infectious Diseases, “G. Martino” University Hospital, Messina, Italy 3Department of Human Pathology of the Adult and the Developmental Age “G. Barresi”, University of Messina, Messina, Italy ABSTRACT: The introduction of combined Anti-Retroviral Therapy has modified the natural history of Hu- man Immunodeficiency Virus (HIV) infection, leading to an increase in life expectancy of the patients living with HIV. Immune deficiency can lead to opportunistic infections and an increased risk of autoimmune dis- ease and malignancy. Here we describe the case of a patient affected by psoriasis, HIV infection and Kapo- si’s Sarcoma. — Keywords: Kaposi’s Sarcoma, Human Immunodeficiency Virus, Psoriasis. INTRODUCTION CASE REPORT The introduction of combined Anti-Retroviral Therapy A 37-year-old man, from Sri-Lanka, was accompanied (cART) has modified the natural history of Human Immu- to the clinic of Infectious Diseases of the “G. Marti- nodeficiency Virus (HIV) infection, leading to an increase no” University Hospital in Messina (Messina, Italy) in life expectancy of the patients living with HIV (PLWH)1- because of a Kaposi’s Sarcoma in nodular phase con- 21. However, it is not able to eliminate the virus22-24. firmed by biopsy. He referred to the dermatologic clin- cART has brought an increased survival and a re- ic for a psoriasis vulgaris poorly responsive to cyclo- duced mortality for Acquired Immune Deficiency Syn- phosphamide.
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