Post-Operative Small Bowel Intussusception in a Pediatric Trauma Patient: a Literature Review and Unique Case Report

Total Page:16

File Type:pdf, Size:1020Kb

Post-Operative Small Bowel Intussusception in a Pediatric Trauma Patient: a Literature Review and Unique Case Report ACS Case Reviews in Surgery Vol. 1, No. 3 Post-Operative Small Bowel Intussusception in a Pediatric Trauma Patient: A Literature Review and Unique Case Report AUTHORS: CORRESPONDENCE AUTHOR:* AUTHOR AFFILIATIONS: Walsh NJa, Dadzie KAb, Jones AJb, Hatley RMa.c Andrew J. Jones, MD a Department of Surgery, Augusta University 1120 15th St, BI-4070 Health, Augusta, GA, USA Augusta, GA, 30912 b Medical College of Georgia at Augusta University, [email protected] Augusta, GA, USA (770) 827-8816 c Section of Pediatric Surgery, Augusta University Health, Augusta, GA, USA Background Intussusception is a well-documented cause of acute abdomen in the pediatric population; however, post-traumatic and post-operative intussusceptions are exceptionally uncommon. Summary An otherwise healthy eight-year-old girl presented as a level II trauma via EMS following a motor vehicle accident (MVA). The patient complained of diffuse abdominal pain and back pain on arrival. Physical exam was remarkable for tachycardia, right coastal margin tenderness to palpation, non-labored breathing, diffuse abdominal tenderness and a seatbelt sign. Abdominal computed tomography (CT) scan was suspicious for duodenal and/or mesenteric injury, warranting an exploratory laparotomy. After this initial operation, she later presented with symptoms of small bowel obstruction. Repeat CT of the abdomen obtained on post-operative day 14 showed dilated loops of distant small bowel, air fluid levels and a swirled appearance of the mesentery, concerning for a closed loop obstruction. She was taken back to the operating room and intra-operative findings revealed a feathery adhesion of the small bowel to the transverse colon with no dilation of the proximal small bowel and a distal jejunojejunal intussusception. Conclusion Due to the rarity of both types of intussusceptions, surgeons and pediatricians alike tend to miss or delay making the diagnosis. Early detection and treatment are essential, and the gold standard of treatment for both posttraumatic and post-operative intussusception is manual surgical reduction. Keywords pediatric, intussusception, post-traumatic intussusception, post-operative intussusception AUTHORS’ CASE STUDY AFFILIATION ADDRESS: CONSENT STATEMENT: Augusta University This article does not contain any studies with human participants or animals Department of Surgery performed by any authors. For this type of study, formal consent is not required. Augusta, GA 30912 FINANCIAL SUPPORT: STATEMENT OF DUPLICATE PUBLICATION: None The authors declare that this case report is not under consideration by any other journal and has not been presented previously. ACKNOWLEDGEMENTS: None DISCLOSURE STATEMENT: The authors declare that they have no conflicts of interest. *PERMANENT ADDRESS: Andrew J. Jones, MD ETHICAL STATEMENT: Department of Surgery The authors declare that they are compliant with COPE standards. Mount Sinai St. Luke’s-Roosevelt 1000 10th Avenue, Suite 2B New York, NY 10019 To Cite: Walsh NJ, Dadzie KA, Jones AJ, Hatley RM. Post-Operative Small Bowel Intussusception in a Pediatric Trauma Patient: A Literature Review and Unique Case Report. ACS Case Reviews in Surgery. 2017;1(3):41-44. American College of Surgeons – 41 – ACS Case Reviews. 2017;1(3):41-44 ACS Case Reviews in Surgery Walsh NJa, Dadzie KAb, Jones AJb, Hatley RMa.c Case Description Focused Assessment with Sonography in Trauma (FAST) was performed in the ED and was negative for any intra-ab- Intussusception, which refers to self-invagination of intes- dominal or cardiac pathology. Computed Tomography tine, is a common cause of acute abdomen. Furthermore, (CT) of abdomen and pelvis showed abnormal wall thick- intussusception is the most common cause of abdominal ening as well as hyper-enhancement and mild dilatation 1 emergencies in children two years of age and younger. of the proximal duodenum suspicious for duodenal and/ The etiology is considered idiopathic in 75 percent of or mesenteric injury, ill-defined right upper quadrant low young children. Other causes include enteric infections or attenuation fluid, and fluid accumulation in the deep pel- underlying disorders such as Meckel’s diverticulum, small vis. These findings were concerning for possible small bow- bowel lymphoma, Henoch-Schonlein purpura, cystic el or mesenteric injury. An emergent laparotomy revealed fibrosis, post-operative and posttraumatic intussusception. mild duodenal hematoma, small bowel mesenteric contu- Post-operative and post-traumatic intussusceptions are sion and transverse colon and duodenal mesenteric defects, 2 very uncommon, with the latter being even less common. which were repaired. Kocher maneuver was performed to fully evaluate the duodenum and nearby structures. There Post-operative intussusception (POI) is well known to was no additional retroperitoneal exploration performed occur mostly after operations involving the gastrointesti- during this laparotomy. nal (GI) system but has also been reported post retroper- itoneal dissections and tumor resections, diaphragmatic The patient’s initial postoperative course was unremark- 3 procedures, and extensive bowel manipulation. Posttrau- able. She had and uneventful stay in the Pediatric Inten- matic intussusception (PTI) is exceedingly rare, with only sive Care Unit (PICU) and was transferred to the pediat- 2,4,5 22 reported cases in the English literature. This usually ric floor on postoperative day three. After the initiation presents after blunt abdominal trauma, and the cause is of clear fluid diet, she complained of abdominal pain and often unknown. We report a case of jejunojejunal intus- nausea and experienced multiple episodes of bilious vom- susception of an eight-year-old girl after blunt abdominal iting. Patient was made NPO and her symptoms initially trauma and exploratory laparotomy. improved, but she again experienced increasing abdominal pain and vomiting after several days. Repeat CT of the An otherwise healthy eight-year-old girl presented as a abdomen obtained on postoperative day 14 showed dilated level II trauma via EMS following a motor vehicle acci- loops of distant small bowel, air fluid levels and a swirled dent (MVA). She was a restrained passenger in the rear appearance of the mesentery, concerning for a closed loop seat behind the driver in an MVA involving her car and obstruction. At immediate exploration, she had a signifi- a school bus. Significant damage was noted to her vehi- cant adhesion from the small bowel to the transverse colon cle. EMS reported possible transient loss of consciousness causing both obstruction and distal long-segment jejuno- during the incident. jejunal intussusception which was manually reduced with- out incident. She tolerated the procedure well and was On arrival, the patient complained of diffuse abdom- admitted back to the floor postoperatively. Her hospital inal pain and back pain on arrival. History was limited course subsequent to her second operation was uneventful. due to patient’s age, clinical condition and absence of a guardian. Physical exam was remarkable for tachycardia, right coastal margin tenderness to palpation, non-labored Discussion breathing, diffuse abdominal tenderness and a seatbelt Even though intussusception is a well-known cause of sign. Laboratory studies revealed a white blood cell count acute abdomen in the pediatric population, the etiology is 3 of 13,400mm, hemoglobin of 13.4g/dL, amylase level usually unknown. Some well-documented causes include of 119U/L, lactic acid of 3.5mmol/L and lipase level of enteric infections, underlying disorders such as Meckel 126U/L. Chest radiograph showed ill-defined opacities in diverticulum, small bowel lymphoma, Henoch-Schonlein the right lung suggestive of pulmonary contusion. A possi- Purpura, and cystic fibrosis. Postoperative and posttrau- ble right proximal humeral fracture (which was later ruled matic intussusception cases are very rare, with the latter out from repeat X rays) and lower lateral right and left rib being even less common. fractures were noted on additional plain films. American College of Surgeons – 42 – ACS Case Reviews. 2017;1(3):41-44 ACS Case Reviews in Surgery Walsh NJa, Dadzie KAb, Jones AJb, Hatley RMa.c POIs have been described following various forms of sur- after initiation of clear fluid diet. This presentation was gical procedures. Approximately 51 percent of POIs occur similar to most POIs reported in literature. Specifically, the following surgeries involving the GI system, 20 percent intussusception occurred after surgery involving the GI sys- postretroperitoneal tumor resections, nine percent fol- tem, presented with bilious vomiting and occurred within lowing diaphragmatic surgeries, six percent after urinary the first week after initial operation. Intramural hemato- system surgeries and four percent postpartial pancreatec- ma, however, was also noted during the first laparotomy, tomy.3 The etiology is thought to be multifocal, but per- as reported in 18 percent of cases of PTIs. Repeat CT was istaltic impairment is believed to be the most prominent concerning for a closed loop obstruction even though an cause.3 Causes of this disorder in peristalsis include exces- intussusception was not reported per se. We are uncertain sive bowel manipulation, abnormal serum electrolytes, if the intussusception was related directly to the intramu- anesthetic agents, post-operatively administered medica- ral hematoma, the initial operation which involved bowel tions or impaired bowel innervation.6 Approximately
Recommended publications
  • Adult Congenital Megacolon with Acute Fecal Obstruction and Diabetic Nephropathy: a Case Report
    2726 EXPERIMENTAL AND THERAPEUTIC MEDICINE 18: 2726-2730, 2019 Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report MINGYUAN ZHANG1,2 and KEFENG DING1 1Colorectal Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000; 2Department of Gastrointestinal Surgery, Yinzhou Peoples' Hospital, Ningbo, Zhejiang 315000, P.R. China Received November 27, 2018; Accepted June 20, 2019 DOI: 10.3892/etm.2019.7852 Abstract. Megacolon is a congenital disorder. Adult congen- sufficient amount of bowel should be removed, particularly the ital megacolon (ACM), also known as adult Hirschsprung's aganglionic segment (2). The present study reports on a case of disease, is rare and frequently manifests as constipation. ACM a 56-year-old patient with ACM, fecal impaction and diabetic is caused by the absence of ganglion cells in the submucosa nephropathy. or myenteric plexus of the bowel. Most patients undergo treat- ment of megacolon at a young age, but certain patients cannot Case report be treated until they develop bowel obstruction in adulthood. Bowel obstruction in adults always occurs in complex clinical A 56-year-old male patient with a history of chronic constipa- situations and it is frequently combined with comorbidities, tion presented to the emergency department of Yinzhou including bowel tumors, volvulus, hernias, hypertension or Peoples' Hospital (Ningbo, China) in February 2018. The diabetes mellitus. Surgical intervention is always required in patient had experienced vague abdominal distention for such cases. To avoid recurrence, a sufficient amount of bowel several days. Prior to admission, chronic bowel obstruction should be removed, particularly the aganglionic segment.
    [Show full text]
  • Intestinal Obstruction
    Intestinal obstruction Prof. Marek Jackowski Definition • Any condition interferes with normal propulsion and passage of intestinal contents. • Can involve the small bowel, colon or both small and colon as in generalized ileus. Definitions 5% of all acute surgical admissions Patients are often extremely ill requiring prompt assessment, resuscitation and intensive monitoring Obstruction a mechanical blockage arising from a structural abnormality that presents a physical barrier to the progression of gut contents. Ileus a paralytic or functional variety of obstruction Obstruction: Partial or complete Simple or strangulated Epidemiology 1 % of all hospitalization 3-5 % of emergency surgical admissions More frequent in female patients - gynecological and pelvic surgical operations are important etiologies for postop. adhesions Adhesion is the most common cause of intestinal obstruction 80% of bowel obstruction due to small bowel obstruction - the most common causes are: - Adhesion - Hernia - Neoplasm 20% due to colon obstruction - the most common cause: - CR-cancer 60-70%, - diverticular disease and volvulus - 30% Mortality rate range between 3% for simple bowel obstruction to 30% when there is strangulation or perforation Recurrent rate vary according to method of treatment ; - conservative 12% - surgical treatment 8-32% Classification • Cause of obstruction: mechanical or functional. • Duration of obstruction: acute or chronic. • Extent of obstruction: partial or complete • Type of obstruction: simple or complex (closed loop and strangulation). CLASSIFICATION DYNAMIC ADYNAMIC (MECHANICAL) (FUNCTIONAL) Peristalsis is Result from atony of working against a the intestine with loss mechanical of normal peristalsis, obstruction in the absence of a mechanical cause. or it may be present in a non-propulsive form (e.g. mesenteric vascular occlusion or pseudo-obstruction) Etiology Mechanical bowel obstruction: A.
    [Show full text]
  • Celiac Disease: It's Autoimmune Not an Allergy
    CELIAC DISEASE: IT’S AUTOIMMUNE NOT AN ALLERGY! Analissa Drummond PA-C Department of Pediatrics Division of Pediatric Gastroenterology HISTORY OF CELIAC DISEASE Also called gluten-sensitive enteropathy and nontropical spue First described by Dr. Samuel Gee in a 1888 report entitled “On the Coeliac Affection” Term “coeliac” derived from Greek word koiliakaos-abdominal Similar description of a chronic, malabsorptive disorder by Aretaeus from Cappadochia ( now Turkey) reaches as far back as the second century AD HISTORY CONTINUED The cause of celiac disease was unexplained until 1950 when the Dutch pediatrician Willem K Dicke recognized an association between the consumption of bread, cereals and relapsing diarrhea. This observation was corroborated when, during periods of food shortage in the Second World War, the symptoms of patients improved once bread was replaced by unconventional, non cereal containing foods. This finding confirmed the usefulness of earlier empirical diets that used pure fruit, potatoes, banana, milk, or meat. HISTORY CONTINUED After the war bread was reintroduced. Dicke and Van de Kamer began controlled experiments by exposing children with celiac disease to defined diets. They then determined fecal weight and fecal fat as a measure of malabsorption. They found that wheat, rye, barley and to a lesser degree oats, triggered malabsorption, which could be reversed after exclusion of the “toxic” cereals from the diet. Shortly after, the toxic agents were found to be present in gluten, the alcohol-soluble fraction of wheat protein. PATHOPHYSIOLOGY Celiac disease is a multifactorial, autoimmune disorder that occurs in genetically susceptible individuals. Trigger is an environmental agent-gliadin component of gluten.
    [Show full text]
  • Adult Intussusception
    1 Adult Intussusception Saulius Paskauskas and Dainius Pavalkis Lithuanian University of Health Sciences Kaunas Lithuania 1. Introduction Intussusception is defined as the invagination of one segment of the gastrointestinal tract and its mesentery (intussusceptum) into the lumen of an adjacent distal segment of the gastrointestinal tract (intussuscipiens). Sliding within the bowel is propelled by intestinal peristalsis and may lead to intestinal obstruction and ischemia. Adult intussusception is a rare condition wich can occur in any site of gastrointestinal tract from stomach to rectum. It represents only about 5% of all intussusceptions (Agha, 1986) and causes 1-5% of all cases of intestinal obstructions (Begos et al., 1997; Eisen et al., 1999). Intussusception accounts for 0.003–0.02% of all hospital admissions (Weilbaecher et al., 1971). The mean age for intussusception in adults is 50 years, and and the male-to-female ratio is 1:1.3 (Rathore et. al., 2006). The child to adult ratio is more than 20:1. The condition is found in less than 1 in 1300 abdominal operations and 1 in 100 patients operated for intestinal obstruction. Intussusception in adults occurs less frequently in the colon than in the small bowel (Zubaidi et al., 2006; Wang et al., 2007). Mortality for adult intussusceptions increases from 8.7% for the benign lesions to 52.4% for the malignant variety (Azar & Berger, 1997) 2. Etiology of adult intussusception Unlike children where most cases are idiopathic, intussusception in adults has an identifiable etiology in 80- 90% of cases. The etiology of intussusception of the stomach, small bowel and the colon is quite different (Table 1).
    [Show full text]
  • Coeliac Disease: the Histology Report
    Digestive and Liver Disease 43S (2011) S385–S395 Coeliac disease: The histology report Vincenzo Villanacci a,*, Paola Ceppa b, Enrico Tavani c, Carla Vindigni d, Umberto Volta e On behalf of the “Gruppo Italiano Patologi Apparato Digerente (GIPAD)” and of the “Società Italiana di Anatomia Patologica e Citopatologia Diagnostica”/International Academy of Pathology, Italian division (SIAPEC/IAP) aDepartment of Pathology, Spedali Civili, Brescia, Italy bSurgical Department, Integrated Morphological and Methods Section of Pathological Anatomy, University of Genova, Genova, Italy cDepartment of Pathology, G. Salvini Hospital Rho, Rho, Italy dDepartment of Pathology and Human Oncology, University of Siena, Siena, Italy eDepartment of Diseases of the Digestive System and Internal Medicine, Policlinico S. Orsola – Malpighi, Bologna, Bologna, Italy Abstract To this day intestinal biopsy is justly considered the “gold standard” for the diagnosis of coeliac disease (CD). The aim of the authors in setting up these guidelines was to assist pathologists in formulating a more precise morphological evaluation of a duodenal biopsy in the light of clinical and laboratory data, to prepare histological samples with correctly oriented biopsies and in the differential diagnosis with other pathological entities and complications of the disease. A further intention was to promote the conviction for the need of a close collaborative relationship between different specialists namely the concept of a “multidisciplinary team”. © 2011 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved. Keywords: Coeliac disease; GIPAD report; T lymphocytes; Malabsorption 1. Introduction based on the most recent acquisitions regarding the diagnosis and pathogenesis of coeliac disease, is the only specialist that These guidelines are intended as an aid for pathologists, can make the final diagnosis of coeliac disease.
    [Show full text]
  • Loop Formation of Meckel's Diverticulum Causing
    Turkish Journal of Trauma & Emergency Surgery Ulus Travma Acil Cerrahi Derg 2011;17 (6):567-569 Case Report Olgu Sunumu doi: 10.5505/tjtes.2011.54533 Loop formation of Meckel’s diverticulum causing small bowel obstruction in adults: report of two cases Erişkinlerde ince bağırsak tıkanıklığına neden olan Meckel divertikülüne bağlı halka oluşumu: İki olgu sunumu Shilpi SINGH GUPTA, Onkar SINGH Meckel’s diverticulum is the most common congenital anom- Meckel divertikülü olguların çoğunluğunda asemptomatik aly of the gastrointestinal tract, and in the majority of cases olarak kalan en yaygın konjenital gastrointestinal sistem it remains asymptomatic. The total lifetime rate of complica- anomalisidir. Yaşam boyu komplikasyon oranı %4’dür. tions is 4%. It is an uncommon cause of intestinal obstruction Erişkinlerde nadir bir intestinal tıkanıklık nedenidir. İnce in adults. Loop formation of Meckel’s diverticulum leading bağırsak tıkanıklığına neden olan Meckel divertikülüne to small bowel obstruction is an extremely rare event. We ilişkin halka oluşumu oldukça enderdir. Biz, Meckel di- report two such cases in which the bowel became obstructed vertikülünün distal ucu ile proksimal ileum ve mezenter and strangulated in a loop formed by adhesion of the distal arasında halka şeklinde adezyonlar oluşmasıyla bağırsa- end of the Meckel’s diverticulum to the proximal ileum and ğın tıkandığı ve strangülasyona uğradığı iki olguyu sunu- mesentery. yoruz. Key Words: Adults; intestinal obstruction; Meckel’s diverticu- Anahtar Sözcükler: Erişkinler; intestinal tıkanıklık; Meckel diver- lum. tikülü. Meckel’s diverticulum is an uncommon cause of rigidity throughout. Bowel sounds were increased. intestinal obstruction in adult life.[1] Rarely, Meckel’s Ultrasonography (USG) of the abdomen revealed hy- diverticulum may form a loop due to adhesions be- perperistaltic dilated small bowel loops.
    [Show full text]
  • Long-Term Follow-Up for Adhesive Small Bowel Obstruction After Open
    ORIGINAL ARTICLE Long-term Follow-up for Adhesive Small Bowel Obstruction After Open Versus Laparoscopic Surgery for Suspected Appendicitis Karolin Isaksson, MD,∗ Agneta Montgomery, MD, PhD,† Ann-Cathrin Moberg, MD, PhD,† Roland Andersson, MD, PhD,∗ and Bobby Tingstedt, MD, PhD∗ A diagnostic laparoscopy is safe and offers the possibility to detect Objective: The aim of the present study was to compare the frequency of read- pathological conditions mimicking appendicitis, especially important missions due to small bowel obstruction (SBO) after open versus laparoscopic in fertile women, and also rendering the option to leave a normal ap- surgery performed for suspected acute appendicitis. pendix in place.11 Background: Appendicitis is a common disease, with a lifetime risk of ap- Postoperative adhesions are quite common, especially not only proximately 7%. Appendectomy is the treatment of choice for most patients. after surgery of the lower part of the abdomen such as gynecological Postoperative adhesions are common after abdominal surgery, including ap- and colorectal surgery but also after appendectomy. Late complica- pendectomy. tions due to intra-abdominal adhesions include chronic abdominal Materials and Methods: Consecutive patients, 16 years or older, operated pain, small bowel obstruction (SBO), and female infertility. These on because of suspected appendicitis at 2 university hospitals between 1992 chronic conditions can result in a major impairment for the patient, a and 2007 were included. The prime approach was open at one hospital and challenge to treat, and represent a major cost for society. In Sweden, laparoscopic at the other hospital. Open and laparoscopic procedures were costs related to admissions due to abdominal adhesions are estimated compared retrospectively, reviewing the patients’ charts until the middle of to about €40 million to €60 million per year.12 Abdominal adhesions 2012.
    [Show full text]
  • Small Bowel Obstruction Following Appendectomy: a Retrospective Study
    New Indian Journal of Surgery21 Original Article January - March 2012, Volume 3 Number 1 Small Bowel Obstruction Following Appendectomy: A Retrospective Study Jyothi S Karegoudar*, Prabhakar PJ**, Rajashri S Patil***, VIjayanath V**** *Asso. Prof in General Surgery, ** Prof & HOD in General Surgery, ***Asst. Prof (biostatistician), S. S. I. M. S & R. C., Davangere, Karnataka State, ****MD, DNB, MNAMS, Associate Professor, Department of Forensic Medicine & Toxicology, Vinayaka Mission’s Kirupananda Variyar Medical College & Hospital, Salem,Tamil Nadu, India. Abstract appendectomy adhesive small bowel The incidence of post-operative small bowel obstruction occurs in 1 to 1.5% of all patients obstruction after standard, open appendectomy was within 14 years of the operation.[1] calculated during five year duration at S. S. Institute Appendectomy is one of the most frequently and Research Centre, Davangere, Karnataka State. performed emergency surgery, and it is Post-operative small bowel obstruction is one of associated with various short and long term the adverse effects of appendectomy but its frequency morbidities. Postoperative small bowel varies from centre to centre. The incidence of small obstruction is recognized as long term adverse bowel obstruction is significantly high in perforated effect of appendectomy.[2] appendicitis, midline incisions, and chronic appendicular pathology. The midline incision has The frequency of this complication is not increased the frequency of post-operative adhesions. well known but the reported risk ranges from This study was conducted to determine the 0.2- 10.7%.[3] The post-operative adhesions incidence of this complication among our patients are a significant problem after colorectal who had open appendectomy and identify the factors surgery.
    [Show full text]
  • Management of Rectal Prolapse –The State of the Art
    Central JSM General Surgery: Cases and Images Bringing Excellence in Open Access Review Article *Corresponding author Adrian E. Ortega, Division of Colorectal Surgery, Keck School of Medicine at the University of Southern California, Los Angeles Clinic Tower, Room 6A231-A, Management of Rectal Prolapse LAC+USC Medical Center, 1200 N. State Street, Los Angeles, CA 90033, USA, Email: sccowboy78@gmail. – The State of the Art com Submitted: 22 November 2016 Ortega AE*, Cologne KG, and Lee SW Accepted: 20 December 2016 Division of Colorectal Surgery, Keck School of Medicine at the University of Southern Published: 04 January 2017 California, USA Copyright © 2017 Ortega et al. Abstract OPEN ACCESS This manuscript reviews the current understanding of the condition known as rectal prolapse. It highlights the underlying patho physiology, anatomic pathology Keywords and clinical evaluation. Past and present treatment options are discussed including • Rectal prolapsed important surgical anatomic concepts. Complications and outcomes are addressed. • Incarcerated rectal prolapse INTRODUCTION Rectal prolapse has existed in the human experience since the time of antiquities. References to falling down of the rectum are known to appear in the Ebers Papyrus as early as 1500 B.C., as well as in the Bible and in the writings of Hippocrates (Figure 1) [1]. Etiology • The precise causation of rectal prolapse is ill defined. Clearly, five anatomic pathologic elements may be observed in association with this condition:Diastasis of Figure 1 surrounded by circular folds of rectal mucosa. the levator ani A classic full-thickness rectal prolapse with the central “rosette” • A deep cul-de-sac • Ano-recto-colonic redundancy • A patulous anus • Loss of fixation of the rectum to its sacral attachments.
    [Show full text]
  • Postoperative Adhesions in Gynecologic Surgery: a Committee Opinion
    ASRM PAGES Postoperative adhesions in gynecologic surgery: a committee opinion Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society of Reproductive Surgeons American Society for Reproductive Medicine, Birmingham, Alabama Postoperative adhesions are a natural consequence of surgical tissue trauma and healing and may result in infertility, pain, and bowel obstruction. Adherence to microsurgical principles and minimally invasive surgery may help to decrease postoperative adhesions. Some surgical barriers have been demonstrated to be effective for reducing postoperative adhesions, but there is no substantial evidence that their use improves fertility, decreases pain, or reduces the incidence of postoperative bowel obstruction. This document replaces the document, ‘‘Pathogenesis, consequences, and control of peritoneal adhesions in gynecologic surgery: a committee opinion,’’ last pub- lished in 2013. (Fertil SterilÒ 2019;112:458–63. Ó2019 by American Society for Reproductive Medicine.) Discuss: You can discuss this article with its authors and other readers at https://www.fertstertdialog.com/users/16110-fertility- and-sterility/posts/50136-28463 INTRODUCTION Health Service hospitals and helped to dian women admitted to the hospital fi Postoperative adhesions are a natural de ne the epidemiology and impact of with a diagnosis of small-bowel consequence of surgical tissue trauma postoperative adhesions (1, 2). Overall, obstruction after gynecologic proced- and healing. Peritoneal adhesions may approximately one third of patients ures found that hysterectomy was a sig- fi result in infertility, pain, or bowel who underwent open abdominal or ni cant cause of adhesion-related obstruction and may increase the tech- pelvic surgery were readmitted an small-bowel obstruction and that lapa- nical difficulty of subsequent abdom- average of 2 times over the subsequent roscopic supracervical hysterectomy inal or pelvic surgery.
    [Show full text]
  • Adhesive Molecules and Inflammatory Markers Among Hepatitis C Virus Saudi Patients
    Eur J Gen Med 2017;14(4):89-93 ISSN:1304-3889 eISSN:1304-3897 Original Article DOI:10.29333/ejgm/81737 Adhesive molecules and inflammatory markers among hepatitis C virus Saudi patients Osama H. Al-Jiffri1 ABSTRACT Background: Currently, about 2% of population are affected with hepatitis C worldwide, chronic hepatitis C (CHC) is the major cause of hepatic cirrhosis and referral for liver transplant. However, there is a high need for noninvasive methods for assessment of hepatocellular damage. Objective: The purpose of this study was to determine the strength of the association between adhesive molecules and inflammatory markers among hepatitis C virus Saudi patients. Methods: One hundred patients with chronic hepatitis C virus infection(64 males and 36 females, their age ranged from 28 to 53 years with circulating anti-HCV antibodies were equally categorized into two study groups: patients with CHC and patients with liver cirrhosis (LC). Also, one fifty healthy subjects were included as healthy controls. Serum alanine aminotransferase (ALT), soluble intercellular adhesion molecule1 (sICAM-1); Soluble vascular adhesion molecule 1(sVCAM-1); Soluble E-selectin(s-E-selectin) and Tumor necrosis factor-alpha (TNF-α) were assayed for all participants. Results: We observed elevation with regard to the healthy controls group in the parameters of ALT, sICAM-1, sVCAM-1, s-E-selectin and TNF-α for patients with CHC and patients with liver cirrhosis (LC). Also, a significant positive correlation between serum TNF-α, sICAM-1, sVCAM-1 and ALT values was detected. Conclusion: In conclusion, our results confirm that, in patients with chronic virus hepatitis and liver cirrhosis there is a significant positive correlation between serum TNF-α, sICAM-1, sVCAM-1 and ALT values.
    [Show full text]
  • Digestive System (Part-I)
    NPTEL – Basic Courses – Basic Biology Lecture 11: Digestive System (Part-I) Introduction: The collective processes by which a living organism takes food which are necessary for their growth, maintenance and energy needs is called nutrition. The chemical substances present in the food are called nutrients. DIFFERENT MODE OF NUTRITION IN ORGANISMS: It is important to know the different modes of nutrition in all living organisms in order to understand energy flow within the ecosystem. Plant produces high energy organic food from inorganic raw materials. They are called autotroph and the mode of nutrition is known as autotrophic nutrition. Animals feed on those high energy organic food, are called as heterotrophs and their mode of nutrition is known as heterotrophic nutrition Heterotrophic nutrition further sub-categorise in holozoic, parasitic, and saprophytic mode of nutrition based on the pattern and class of food that is taken inside. Holozoic Nutrition: It involves taking entire organic food and this can be in the form of whole part of plant or animal. Most of the free living protozoans, humans and other animals fall under this category. Saprophytic Nutrition: The organism fulfils the requirement of food from the rotten parts of dead organisms and decaying matter. The organisms secrete digestive enzymes outside the body on their food and then take in digested food. It is a kind of extra-cellular digestion. Examples: Housefly, Spiders etc. Parasitic Nutrition: The organism fulfils the requirement of food from the body of another organism. The parasites are of two distinct types, one which lives inside the host and the other which lives outside.
    [Show full text]