Table S4. Altered expression of breast cancer prognostic markers in MCF7-T and MCF7-F cells Fold change (vs. MCF7) symbol genbank MCF7-T MCF7-F Description

Poor prognostic markers of breast cancer ADM NM_001124 - 3.40 ALDH3B1 NM_000694 - 4.66 Aldehyde dehydrogenase 3 family, member B1 ARMC1 NM_018120 - 1.85 Armadillo repeat containing 1 ASPM NM_018136 2.82 2.54 Asp (abnormal spindle)-like, microcephaly associated (Drosophila) ATAD2 NM_032365 1.65 2.40 ATPase family, AAA domain containing 2 BIRC5 NM_001168 2.08 -3.47 Baculoviral IAP repeat-containing 5 (survivin) BM039 NM_018455 2.19 -3.48 Uncharacterized bone marrow BM039 BUB1 NM_004336 1.82 2.29 BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) CCNB2 NM_004701 2.00 -1.67 Cyclin B2 CCNE2 NM_057749 1.34 3.80 Cyclin E2 CCNF NM_001761 - 7.18 Cyclin F CENPF NM_016343 2.20 2.16 Centromere protein F, 350/400ka (mitosin) CHKA NM_001277 -1.66 4.24 Choline kinase alpha CP NM_000096 - 3.48 Ceruloplasmin (ferroxidase) CSF1 NM_172212 - 2.63 Colony stimulating factor 1 (macrophage) CTSF NM_003793 - 2.00 Cathepsin F CTSL2 NM_001333 2.20 2.17 Cathepsin L2 CYP4F12 NM_023944 - 10.00 Cytochrome P450, family 4, subfamily F, polypeptide 12 DEGS NM_144780 - 3.26 Degenerative spermatocyte homolog, lipid desaturase (Drosophila) DEPDC1 NM_017779 3.04 3.85 DEP domain containing 1 DKFZp762E1312 NM_018410 2.68 2.08 Hypothetical protein DKFZp762E1312 DLG7 NM_014750 2.94 - Discs, large homolog 7 (Drosophila) ELAVL2 NM_004432 - 2.25 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 EPOR NM_000121 - 1.66 ESD NM_001984 1.35 8.81 Esterase D/formylglutathione hydrolase EXT1 NM_000127 - 5.65 Exostoses (multiple) 1 FBLN1 NM_006487 - 8.59 Fibulin 1 FLJ10156 NM_019013 1.67 2.14 Hypothetical protein FLJ10156 FLJ10901 NM_018265 - 1.95 Hypothetical protein FLJ10901 FLJ12443 NM_024830 -1.76 2.62 Hypothetical protein FLJ12443 GABBR1 NM_021905 2.15 2.41 Gamma-aminobutyric acid (GABA) B receptor, 1 GALNS NM_000512 - 2.45 Galactosamine (N-acetyl)-6-sulfate sulfatase GGH NM_003878 1.49 2.67 Gamma-glutamyl hydrolase H6PD NM_004285 - 1.52 Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) HRB NM_004504 -1.32 5.46 HIV-1 Rev binding protein IDS NM_006123 -2.39 8.30 Iduronate 2-sulfatase (Hunter syndrome) ITGAV NM_002210 - 2.66 Integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) JAG1 NM_000214 1.48 11.35 Jagged 1 (Alagille syndrome) KIF14 NM_014875 2.21 - Kinesin family member 14 KNTC2 NM_006101 3.32 - Kinetochore associated 2 KRT13 NM_153490 - 18.72 Keratin 13 KRT4 NM_002272 - 11.92 Keratin 4 LCHN AF136629 1.32 6.24 LCHN protein MST1 NM_020998 - 1.65 Macrophage stimulating 1 (-like) MVK NM_000431 - 2.12 Mevalonate kinase (mevalonic aciduria) NUSAP1 NM_018454 2.90 1.64 Nucleolar and spindle associated protein 1 ORC6L NM_014321 - 1.58 Origin recognition complex, subunit 6 homolog-like (yeast) PCSK7 NM_004716 - 7.51 Proprotein convertase subtilisin/kexin type 7 PGK1 NM_000291 -1.33 9.53 Phosphoglycerate kinase 1 PITRM1 NM_014889 - 2.35 Pitrilysin metalloproteinase 1 PRC1 NM_199414 2.56 - Protein regulator of cytokinesis 1 Table S4. Altered expression of breast cancer prognostic markers in MCF7-T and MCF7-F cells (continued) Basal expression (vs. MCF7) gene symbol genbank MCF7-T MCF7-F Description

Poor prognostic markers of breast cancer PRKR NM_002759 - 4.35 Protein kinase, -inducible double stranded RNA dependent PSMD7 NM_002811 - 36.23 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 RAD21 NM_006265 - 3.48 RAD21 homolog (S. pombe) SMC4L1 NM_005496 1.99 3.85 SMC4 structural maintenance of 4-like 1 (yeast) TFAP2A NM_003220 5.05 6.15 Transcription factor AP-2 alpha TFRC NM_003234 - 65.12 Transferrin receptor (p90, CD71) TMEFF1 NM_003692 1.42 2.14 Transmembrane protein with EGF-like and two follistatin-like domains 1 TRIP13 NM_004237 1.42 3.73 Thyroid interactor 13 TROAP NM_005480 2.63 -2.09 Trophinin associated protein (tastin) UBE3B NM_183415 - 4.04 Ubiquitin protein ligase E3B VEGF NM_003376 1.20 3.05 Vascular endothelial growth factor

Good prognostic markers of breast cancer ALDH4A1 NM_170726 -2.97 - Aldehyde dehydrogenase 4 family, member A1 ALDH6A1 NM_005589 1.67 -4.27 Aldehyde dehydrogenase 6 family, member A1 EVL NM_016337 1.68 -2.65 Enah/Vasp-like FBP1 NM_000507 -1.31 -2.82 Fructose-1,6-bisphosphatase 1 GSTM3 NM_000849 - -8.26 Glutathione S-transferase M3 (brain) KIAA1181 NM_020462 -2.49 -2.60 Endoplasmic reticulum-golgi intermediate compartment 32 kDa protein KIAA1324 NM_020775 1.59 -20.11 Maba1 KIF3B NM_004798 -2.33 -1.46 Kinesin family member 3B PECI NM_006117 - -2.19 Peroxisomal D3,D2-enoyl-CoA isomerase PEX12 NM_000286 - -2.10 Peroxisomal biogenesis factor 12 QDPR NM_000320 - -2.05 Quinoid dihydropteridine reductase RAB27B NM_004163 -5.43 -1.92 RAB27B, member RAS oncogene family