Final Program
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International Eosinophil Society, Inc. Final Program 9th Biennial Symposium 14-18 July 2015 Chicago, IL Holiday Inn Mart Plaza Board of Directors 2013-2015 President At-Large Directors Hans-Uwe Simon, MD, PhD Patricia T. Bozza, MD, PhD University of Bern Instituto Oswaldo Cruz Bern, Switzerland Rio de Janeiro, Brazil Simon P. Hogan, PhD President-Elect Cincinnati Children’s Hospital Peter Weller, MD Cincinnati, Ohio Harvard University United States Boston, Massachusetts United States Leo Koenderman, PhD University Medical Center Utrecht Utrecht, Netherlands Immediate Past-President Amy D. Klion, MD James J. Lee, PhD National Institutes of Health Mayo Clinic Arizona Baltimore, Maryland Scottsdale, Arizona United States United States Kenji Matsumoto, MD, PhD Secretary-Treasurer National Research Institute Hirohito Kita, MD Tokyo, Japan Mayo Clinic Rochester Parameswaran Nair, MD Rochester, Minnesota McMaster University United States Hamilton, Ontario Canada Scienti!c Program Director Bruce S. Bochner, MD Marc Rothenberg, MD, PhD Northwestern University Cincinnati Children’s Hospital Chicago, Illinois Cincinnati, Ohio United States United States Florence Roufosse, MD, PhD Trainee Board Member Hospital Erasme (ULB) Neda Farahi, BSc, PhD Brussels, Belgium University of Cambridge Lisa A. Spencer, PhD Cambridge, United Kingdom Beth Israel Deaconess Medical Center Boston, Massachusetts United States Andrew Wardlaw, MD Glen!eld Hospital Leicester, United Kingdom 9th Biennial Symposium • 14-18 JULY 2015 • CHICAGO, IL • HOLIDAY INN MART PLAZA 1 Table of Contents Welcome ...................................................................................................................................................................................................................................................................................3 Acknowledgements ..........................................................................................................................................................................................................................................................4 General Information ..........................................................................................................................................................................................................................................................5 Pre-Conference Workshop Agenda .........................................................................................................................................................................................................................6 Scientic Program ...............................................................................................................................................................................................................................................................8 Awards .....................................................................................................................................................................................................................................................................................20 In Memoriam .......................................................................................................................................................................................................................................................................23 Invited Speaker Abstracts ............................................................................................................................................................................................................................................24 Oral Abstracts ......................................................................................................................................................................................................................................................................32 Poster Session Abstracts ..............................................................................................................................................................................................................................................46 Participant List ....................................................................................................................................................................................................................................................................98 2 9th Biennial Symposium • 14-18 JULY 2015 • CHICAGO, IL • HOLIDAY INN MART PLAZA Welcome Welcome fellow eosinomaniacs! After years of planning, we are excited to host you in Chicago for the 9 th Biennial Symposium of the International Eosinophil Society, Inc. The 2015 meeting, just like prior ones, should be an ideal opportunity for each of us to explore interests, ideas and collaborations in an environment of openness and collegiality. For those of you that have attended prior meetings, the structure and format of the meeting should feel familiar, but for those of you attending for the rst time, here is a brief overview. Tuesday’s pre-conference meeting will be devoted to the 7 th in a series of clinically oriented workshops. The morning session, organized by Marc Rothenberg and Glenn Furuta, will focus on eosinophilic gastrointestinal diseases, and the afternoon session, assembled by Amy Klion, will focus on biologic therapies for eosinophilic disor- ders. The main meeting will open on Tuesday evening with a reception that will include a talk by Bill Busse and our second annual Eosinophil Jeopardy contest. Sessions beginning Wednesday morning and continuing until midday Saturday, will highlight the lat- est advances in basic and clinical research, presented as state-of-the-art talks by leaders in the eld, cutting edge lectures on new ndings, and oral presentations and posters taken from over 100 submitted abstracts. New to the meeting on Thursday morning is a breakfast symposium, presented by the World Allergy Organization. There will be plenty of opportunities for discussion during the three poster sessions, and prizes will be given to trainees at the Friday night Awards Dinner for best posters and oral presentations. Of course, there will be free time each afternoon and Thursday evening for exploration of Chicago, with its world-class museums, parks, beaches, music, food, shopping and architecture under what we hope will be warm sunny skies. Did you know that the Art Institute of Chicago, just a 25 minute walk from the hotel, was voted the #1 museum in the world? Finally, we would like to extend our extreme gratitude to our corporate and non-prot sponsors and volunteers, without whom this meeting would never have been possible; to Steve Ackerman, whose eorts once again resulted in our ability to oer travel grants to trainees; for the time and eort of our colleagues among the IES leadership and others who served on the meeting’s vari- ous committees; and to Kate Filipiak, Ashley Salmon and Kris Heijnen at EDI, whose guidance, professionalism, patience, and skills insured the successful organization of this meeting and made the process such a pleasure. We hope you enjoy the meeting! Hans-Uwe Simon President Bruce Bochner Scientic Program Director 9th Biennial Symposium • 14-18 JULY 2015 • CHICAGO, IL • HOLIDAY INN MART PLAZA 3 Acknowledgements IES thanks the following partners for their support of the 9th Biennial Symposium Gold Supporters MedImmune/AstraZeneca Teva Respiratory Silver Supporters /DDhEWŚĂƌŵĂĐĞƵƟĐĂůƐ Receptos Roche Takeda Bronze Supporters Allakos Apfed CURED ŝĂŐŶŽƐƟĐƐĞǀĞůŽƉŵĞŶƚ Knopp Biosciences TIGER Additional Support EŽǀĂƌƟƐ/ŶƐƟƚƵƚĞƐĨŽƌŝŽDĞĚŝĐĂůZĞƐĞĂƌĐŚ͕/ŶĐ͘ Society Sponsors ŵĞƌŝĐĂŶĐĂĚĞŵLJŽĨůůĞƌŐLJ͕ƐƚŚŵĂΘ/ŵŵƵŶŽůŽŐLJ European Academy of Allergy and Clinical Immunology Speaker Travel Support Ku Leuven VIB Grant Support EĂƟŽŶĂů/ŶƐƟƚƵƚĞƐŽĨ,ĞĂůƚŚ &ƵŶĚŝŶŐĨŽƌƚŚŝƐĐŽŶĨĞƌĞŶĐĞǁĂƐŵĂĚĞƉŽƐƐŝďůĞŝŶƉĂƌƚďLJϭZϭϯ/ϭϭϴϬϵϴͲϬϭĨƌŽŵƚŚĞEĂƟŽŶĂů/ŶƐƟƚƵƚĞŽĨůůĞƌŐLJĂŶĚ/ŶĨĞĐƟŽƵƐŝƐĞĂƐĞƐ͘dŚĞǀŝĞǁƐ ĞdžƉƌĞƐƐĞĚŝŶǁƌŝƩĞŶĐŽŶĨĞƌĞŶĐĞŵĂƚĞƌŝĂůƐŽƌƉƵďůŝĐĂƟŽŶƐĂŶĚďLJƐƉĞĂŬĞƌƐĂŶĚŵŽĚĞƌĂƚŽƌƐĚŽŶŽƚŶĞĐĞƐƐĂƌŝůLJƌĞŇĞĐƚƚŚĞŽĸĐŝĂůƉŽůŝĐŝĞƐŽĨƚŚĞĞƉĂƌƚŵĞŶƚ ŽĨ,ĞĂůƚŚĂŶĚ,ƵŵĂŶ^ĞƌǀŝĐĞƐ͖ŶŽƌĚŽĞƐŵĞŶƟŽŶŽĨƚƌĂĚĞŶĂŵĞƐ͕ĐŽŵŵĞƌĐŝĂůƉƌĂĐƟĐĞƐ͕ŽƌŽƌŐĂŶŝnjĂƟŽŶƐŝŵƉůLJĞŶĚŽƌƐĞŵĞŶƚďLJƚŚĞh͘^͘'ŽǀĞƌŶŵĞŶƚ͘ 4 9th Biennial Symposium • 14-18 JULY 2015 • CHICAGO, IL • HOLIDAY INN MART PLAZA General Information Coee Breaks Social Events Coee breaks are included in the registration fee for attendees and will be served daily. Coee will be served outside of the Welcome Reception and Dinner Sauganash Grand Ballroom. Please check the Scientic Program Tuesday, 14 July, 17:30-21:00 for exact times. The welcome reception will be held at the Holiday Inn Mart Education Sessions Plaza in the LaSalle room located on the 15th !oor. Refresh- ments and dinner will be provided. All education sessions will take place in the Sauganash Grand Ballroom East located on the 14th !oor of the Holiday Inn Mart Plaza. Chicago River Architectural Boat Ride and Pizza Party Wednesday, 15 July, 19:15-21:45 Meals The boat ride will depart at 19:15 from the Trump Towers boat Continental breakfast will be available each morning prior to dock located on the lower level of Rush Street and Kinsie Street the rst session. Breakfast will be served outside the Sauganash behind the Trump Towers hotel. Grand Ballroom. Walking directions from Holiday Inn: Exit Merchandise Mart at Kinsie and Wells Streets, continue on Kinsie heading east until Poster Sessions