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ABSTRACTS: 15Th International Chromosome Conference (ICC CHROMOSOME RESEARCH http://www.kluweronline.com/issn/0967-3849 Contents Volume 12 Supplement 1 September 2004 ICC XV,15th International Chromosome Conference 5^10 September 2004 Brunel University,West London, UK Edited by: Joanna M. Bridger Darren K. Griffin Editorial v Conference Programme xi Plenary Session: Lectures L01^L07 1 Animal Chromosomes Symposium: Lectures L09^L17; Posters PO:06:01^PO:06:15 3 Centromeres Symposium: Lectures L18^L28; Posters PO:06:16^PO:06:22 14 Genome Organisation Symposium: Lectures L29^L46; Posters PO:06:23^PO:06:32 21 Reproduction Symposium: Lectures L47^L54; Posters PO:06:33^PO:06:36 34 Comparative Genomics/Chromosome Evolution Symposium: Lectures L55^L65; Posters PO:06:37^PO:06:55 40 Telomeres Symposium: Lectures L66^L70; Posters PO:06:56^PO:06:64 55 Epigenetics Symposium: Lectures L71^L78; Posters PO:06:65^PO:06:71 61 Plant Chromosomes Symposium: Lectures L79^L90; Posters PO:06:72^PO:06:94 67 Prokaryote Chromosomes Symposium: Lectures L91^L95; Posters PO:08:01^PO:08:02 84 Sex Chromosomes Symposium: Lectures L96^L107; Posters PO:08:03^PO:08:14 87 Chromosome Transfer Symposium: Lectures L108^L111 Posters PO:08:15^PO:08:16 98 Gene Therapy Symposium: Lectures L112^L119; Posters PO:08:17^PO:08:22 101 Meiosis Symposium: Lectures L120^L126; Posters PO:08:23^PO:08:36 107 Population Cytogenetics Symposium: Lectures L127^L137; Posters PO:08:37^PO:08:53 117 Solid Tumours Symposium: Lectures L138^L147; Posters PO:08:54^PO:08:64 128 Aneuploidy Symposium: Lectures L148^L155; Posters PO:08:65^PO:08:77 137 New Methodologies Symposium: Lectures L156^L165; Posters PO:08:78^PO:08:83 146 Haematological Malignancy Symposium: Lectures L166^L174; Posters PO:08:84^PO:08:94 152 Post-genomic Era Symposium: Lectures L175^L180 161 Prize Nominee Special Symposium: Lectures L181^L191 163 Author Index 171 Important Notes and Reminders for Authors inside back cover CHROMOSOME RESEARCH Cytogenetics, Genomics, Chromatin and The Nucleus FRONT COVER PICTURE 3D reconstruction of a mouse fibroblast (NIH3T3) nucleus after visualization of telomeres by 3D-FISH and DNA counterstaining. The border of the nucleus (red outside, grey inside) was reconstructed using TO-PRO-3 counterstain and then partly removed to show the inside with reconstructed telomere signals (green). Segmentation of the nucleoli (yellow) was performed using the counterstain labelling. Maximum intensity projections (XY, XZ, YZ) of false-colouredimagestacks are shown on the background. Laser confocal serial sections were recorded by a confocal microscope (Leica TCS SP) with a voxel size ¼ 0.05 Â 0.05 Â 0.250 mm. Reconstruction was performed by surface rendering using software AmiraTM (Amira 3.0, TGS Europe, Merignac, France; http://www.amiravis.com). FISH experiment and 3D reconstruction were performed in the laboratory of Prof. T. Cremer by A. Brero, Department of Biology II, University of Munich, Germany. Chromosome Research is covered in Biochemistry & Biophysics Citation Index, Biological Abstracts, BIOSIS Previews, Biotechnology Citation Index, Chemical Abstracts, Current Contents/Life Sciences, Elsevier BIOBASE/Current Awareness in Biological Sciences, EMBASE/Excerpta Medica, IBIDS, Index Medicus/MEDLINE, The ISI Alerting Services, Science Citation Index, Science Citation Index Expanded, and in CD-ROM via Adonis. SUBSCRIPTION INFORMATION Chromosome Research is published 8 times a year (2004). Subscription prices year 2004 (Volume 12, 8 issues) including postage and handling: EUR 1248.00/USD 1248.00 (print or electronic access), EUR 1497.60/USD 1497.60 (print and electronic access). Personal price per volume: EUR 350.00/USD 350.00 including postage and handling. Subscriptions should be sent to Kluwer Academic Publishers Group, PO Box 322, 3300 AH Dordrecht, The Netherlands,oratPO Box 358, Accord Station, Hingham, MA 02018-0358, USA, or to any subscription agent. For advertisement rates, prices of back volumes, and other information, please apply to Kluwer Academic Publishers, PO Box 17, 3300 AA Dordrecht, The Netherlands. Fax: (+31)-78-6183273. Photocopying. In the USA: This journal is registered at the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923. Authorisation to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Kluwer Academic Publishers, for users registered with the Copyright Clearance Center (CCC). The ‘‘services’’ for users can be found on the internet at hwww.copyright.comi. For those organ- isations that have been granted a photocopy licence, a separate system of payment has been arranged. Authorisation does not extend to other kinds of copying, such as that for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale. Intherestoftheworld:Permission to photocopy must be obtained from the copyright holder. Please apply to Kluwer Academic Publishers, PO Box 17, 3300 AA Dordrecht, The Netherlands. Chromosome Research is published monthly except for March, June, September and December. Subscription price, per volume: USD 1248.00 Periodicals postage paid at Rahway, NJ 07001. ISSN 9067-3849. US Mailing Agent: Mercury Airfreight International Ltd., 365 Blair Road, Avenel, NJ 07001. Published by Kluwer Academic Publishers, Van Godewijckstraat 30, 3311 GX Dordrecht, The Netherlands, and 101 Philip Drive, Norwell, MA 02061, USA. Postmaster: please send all address corrections to: Chromosome Research, c/o Mercury Airfreight International Ltd., 365 Blair Road, Avenel, NJ 07001, USA. Consent to publish in this journal entails the author’s irrevocable and exclusive authorisation of the publisher to collect any sums or considerations for copying or reproduction payable by third parties (as mentioned in article 17, paragraph 2, of the Dutch Copyright Act of 1912 and in the Royal Decree of June 20, 1974 (S.351) pursuant to article 16b of the Dutch Copyright Act of 1912) and/or to act in or out of court in connection herewith. Printed on acid-free paper # 2004 Kluwer Academic Publishers. Printed in the Netherlands ICC XV 15th International Chromosome Conference September 5^10, 2004; Brunel University,London, UK CONFERENCE ORGANIZING COMMITTEES Local Organizers Hosts: Joanna Bridger and Darren Griffin (Cell and Chromosome Biology Group, Brunel University) Zac Peake (Cambridge Publications) Jackie Storey (Cambridge Publications) Charmaine Grimes (Brunel Conferencing Services) Shiela Killen (Brunel Conferencing Services) Standing Committee of the International Chromosome Conferences Hans de Jong (Wageningen,The Netherlands) Peter Moens (Toronto, Canada) Ettore Olmo (Ancona, Italy) Maria Puertas (Madrid, Spain) Jeremy Searle (York, UK) Adrian Sumner (North Berwick, UK) ^ Chair DwayneWise (Mississippi, USA) International Advisory Board Martin Bentz (Ulm, Germany) Harold Klinger (NewYork, USA) Adrian Bird (Edinburgh, UK) Peter Lichter (Heidelberg, Germany) Nigel Carter (Cambridge, UK) Richard Losick (Harvard, USA) Titia De-Lange (NewYork, USA) Jennifer Marshall-Graves (Canberra, Australia) Joy Delhanty (London, UK) Rob Newbold (Brunel University,UK) Bill Earnshaw (Edinburgh, UK) Michael Schmid (Wuerzburg, Germany) Malcolm Ferguson-Smith (Cambridge, UK) Jeremy Searle (York, UK) Terry Hassold (Cleveland, USA) Kevin Sullivan (La Jolla, USA) Pat Heslop-Harrison (Leicester, UK) HansTanke (Leiden, Netherlands) Pat Hunt (Cleveland, USA) AndrewWright (Boston, USA) Clare Huxley (London, UK) Chromosome Research 12 (Suppl 1): v–x, 2004. v # 2004 Kluwer Academic Publishers. Printed in the Netherlands Editorial ICC XV, 15th International Chromosome We were also overwhelmed by the response of our Conference would-be presenters at the conference; around 5^10 September 2004, Brunel University 250 new abstracts were received (in addition to those of our invited speakers) and approximately This issue of Chromosome Research contains the 100 of these have been selected as oral abstracts of ICC XV, the 15th International presentations. In addition there will be two pos- Chromosome Conference held at Brunel ter sessions, collectively comprising around 150 University on 5–10 September 2004. The Inter- posters accompanied by our commercial exhibi- national Chromosome Conferences began in tion space. We hope to have over 700 delegates, 1964, 1967 and 1970 as the Oxford Chromosome each contributing to the unique nature of ICC. Conferences. They became ‘‘International’’ at Our intention is to create an atmosphere of the the fourth conference in Jerusalem in 1972 and a highest quality science and the opportunity for tri-annual format has continued more or less delegates to discuss new projects and ideas in a thereafter with conferences in Leiden (1974), relaxed environment. It is our belief that the best Helsinki (1977), Oxford (1980), Lubeck (1983), science is not always done in the lecture rooms Marseille (1986), Uppsala (1989), Edinburgh but in the bars (i.e. The Chromosome Arms, spe- (1992), Madrid (1995), Ancona (1998) and Wurz- cially renamed for the conference) and dining burg (2001). The year 2004 sees a return to the rooms of conference centres. The International UK and a first chance for Brunel University to Chromosome Conferences have always promoted host the ICC. The decision to hold ICC XV at the social side of conferencing as well as the sci- Brunel was initiated in a Franconian wine cellar ence and ICC XV will be no exception. At ICC at The Residence in Wurzburg and we’d like to XV there will be visits to the West End, Windsor think that
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