DNAJA1 Antibody Cat. No.: 14-063

DNAJA1 Antibody

Immunofluorescence analysis of NIH/3T3 cells using DNAJA1 antibody (14-063) at dilution of 1:100. Blue: DAPI for nuclear staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 178-397 IMMUNOGEN: of human DNAJA1 (NP_001530.1).

TESTED APPLICATIONS: IF, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IF: ,1:50 - 1:200

POSITIVE CONTROL: 1) MCF7

2) HeLa

September 23, 2021 1 https://www.prosci-inc.com/dnaja1-antibody-14-063.html 3) Jurkat

4) U-87MG

5) HepG2

6) Mouse brain

PREDICTED MOLECULAR Observed: 45kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: DNAJA1

DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, HSDJ, Heat shock 40 kDa ALTERNATE NAMES: protein 4, J2, HSJ-2, Human DnaJ protein 2, hDj-2, DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4

GENE ID: 3301

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes a member of the DnaJ family of , which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate , trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich BACKGROUND: region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other .

September 23, 2021 2 https://www.prosci-inc.com/dnaja1-antibody-14-063.html ANTIBODIES FOR RESEARCH USE ONLY.

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September 23, 2021 3 https://www.prosci-inc.com/dnaja1-antibody-14-063.html