BLI News 97 #3
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IN THE NEWS Director’s Message 3 LASER Skin Resurfacing Breakthrough 4 New Device Aids Cell Analysis 5 BECKMAN LASER INSTITUTE S p r i n g 1 9 9 9 The Whitaker Foundation recently nanoscale systems, and biomedical Whitaker granted UCI a $3 million Development computation. Biophotonics use light to Award to launch a nationally-recog- make diagnostic instruments and nized program in biomedical engineer- therapeutic devices for cancer, heart Grants $3 ing. disease and other diseases; nanoscale “We were impressed,” said Peter systems use computer chips and tiny Katona, Whitaker Foundation presi- mechanical robots to monitor and ma- Million Award dent of biomedical engineering pro- nipulate body functions; computation grams, “by the scope of UCI’s goals and employs computers to identify genes, the plans for achieving improve medical imaging, and model them. The prospect for light transport through tissue. building an influential bio- Whitaker funding also will help to medical engineering pro- equip core technology development gram is excellent.” labs, to fund undergraduates, gradu- BLI Director Michael ate students and postdoctoral research- Berns, Ph.D., who also co- ers, and to recruit as many as 12 new directs the UCI Biomedical faculty. Engineering Center, says The impact of the award will be felt UCI is honored to be cho- by students on many levels. New bio- sen for a Development medical engineering coursework lead- Award. ing to an undergraduate minor will be “This is an exciting op- offered in the 1999-2000 school year. portunity,” Berns says, “Our intent is to offer full under- “for UCI and the Beckman graduate and graduate programs by Laser Institute to play a 2001,” says Steve George, M.D., Ph.D., Institute Assistant Professor Zhongping Chen has major role in shaping bio- assistant professor and biomedical en- engineered a biomedical device to gauge subsurface blood flow. medical engineering in the gineering program co-director. 21st century.” Talks also are underway at the UCI’s Development Award is only School of Engineering about the pros- the 11th such award granted by pect of forming an academic Depart- Whitaker in the past 10 years. ment of Biomedical Engineering in the The four-year award will support future. biomedical engineering research al- The Whitaker Foundation, based in ready taking place at the College of Rosslyn, Va., was established after the Medicine, the Schools of Engineering, death of Uncas A. Whitaker, founder Biological Sciences and Physical Sci- of AMP, the world’s largest manufac- ences, and at the Beckman Laser Insti- turer of electrical connection devices. tute. The 24-year-old foundation plans to Research will build on UCI’s give away its $430 million endowment strengths in biophotonics, biomedical by the end of 2006. ■ N E W S B R I E F S Institute Scientists Win Kudos Professor To Chair Conference J. LaMorte, Ph.D., a four-year research Fulbright Selects BLI Scientist Associate Director J. Stuart Nelson, grant. LaMorte will use the $260,000 Tuan Pham, a medical and doctoral M.D., Ph.D., was elected chairman of award to study sterol regulatory bind- student working in Associate Professor the Gordon Research Conference on ing proteins, the transcription factor Tromberg’s research group, was chosen “Lasers in Medicine and Biology” to be proteins important in cholesterol regu- for a J. William Fulbright Foreign Schol- held June 11-16, 2000. lation and, ultimately, coronary heart arship. The scholarship will fund 10 The Gordon Research Conferences disease. months of research at Lund University promote discussions of leading-edge Laser Medical Centre in Sweden begin- research in the biological, chemical and NIH Renews Grant ning in August. physical sciences. The NIH awarded Principal Inves- While in Sweden, Pham will study tigator (PI) Michael Berns, Ph.D., and quantitative tissue optical spectroscopy Editor Appointed co-PI Yona Tadir, M.D., $1.3 million to using ultra-fast, white light pulses. He Bruce Tromberg, Ph.D., associate continue research on photodynamic plans to measure tissue absorption and professor at the Beckman Laser Insti- therapy. The four-year renewal will scattering over a wide range of wave- tute and director of the Laser Micro- support ongoing basic and clinical re- lengths. By using many wavelengths, beam and Medical Program, was search that may one day yield effective Pham hopes that it will be easier to dif- named editor-in-chief of the Journal of treatments for cervical disease and ova- ferentiate normal tissue from tumor tis- Biomedical Optics. rian cancer. sue. ■ Published quarterly by the Interna- tional Society for Optical Engineering, Beckman Laser Institute and Medical Clinic the journal features peer-reviewed pa- University of California, Irvine pers on the use of optical technologies 1002 Health Sciences Road East in medicine and biology. Irvine, CA 92612 (949) 824-4713 (Administration) (949) 824-7980 (Clinic) Scientist Wins NIH Grant Assistant Professor Brian Wong, Board of Directors M.D., recently was honored with a Richard P. Kratz, M.D., Chairman Mentored Clinical Scientist Develop- Arnold O. Beckman, Ph.D., Chairman Emeritus Michael W. Berns, Ph.D., President and CEO ment Award from the National Insti- Linda Cahill, Vice Chair tutes of Health (NIH). George E. Hewitt, Secretary/Treasurer The $550,000 grant will fund Wong’s George L. Argyros Brian M. Demsey Richard A. Nesbit., Ph.D. ongoing study of laser reshaping of car- Patricia Beckman Harry Gray, Ph.D. Robert L. Stoy, Ph.D. tilage. Although cartilage is widely Thomas C. Cesario, M.D. Gavin S. Herbert David S. Tappan, Jr. used in reconstructive surgery, it is not always available in the right size. The Administration Michael W. Berns, Ph.D., President and CEO five-year award will help Wong de- J. Stuart Nelson, M.D., Ph.D., Associate Director velop a method to reshape cartilage Ruth Bundy, Ph.D., R.N., Clinic Administrative Director rapidly and safely. George M. Peavy, D.V.M., Veterinary Director Rachel Schreiman, C.P.A., M.B.A., Director of Finance Joyce Zeiler, R.N., Nurse Director Heart Grant Awarded The American Heart Association Beckman Laser Institute News has awarded Assistant Professor Vickie Nicole Knight 2 D I R E C T O R’ S M E S S A G E Arnold Beckman: A Scientific Life and Legacy s Dr. Arnold Beckman turns 99, awards, and the Ait seems appropriate to take a few research under- moments to reflect on the life of this way at the five great man. Beckman insti- Throughout the course of his life, tutes and cen- honors and awards have been heaped ters, bode well on Dr. Beckman (they keep coming— for the future of and rightly so). In fact, he recently was science in the awarded the 1999 Public Welfare Medal U.S. by the National Academy of Sciences The wisdom in Washington, D.C. I consider him one of Dr. Beckman of the greatest philanthropists of our is not only time, as do many others. manifest in his generous sup- The Beckman Foundation port of science Dr. Beckman, through the Arnold and scientists and Mabel Beckman Foundation, has but also (and given away approximately $300 mil- perhaps more Dr. Beckman and his daughter Pat celebrated his 99th birthday lion to various scientific programs. importantly) in with Dr. Berns, scientists and staff at the Beckman Laser Institute. This Foundation, in addition to pro- his decision to viding research support to the continue the Beckman Foundation into thrilling to still see the twinkle in his Beckman Laser Institute, also funds the perpetuity. eyes when he listens to young scien- Beckman centers at the California In- tists describe their newest research. stitute of Technology, the University of Science Is Its Mission Illinois, Urbana-Champaign, City of Ten years ago, Dr. Beckman revised A Lasting Scientific Legacy Hope Hospital and Medical Center, the Foundation’s mission to include Because of his vision and through and Stanford University. “preserving and enhancing the capital the legacy of his Foundation (com- The Foundation also supports the assets and distributing revenue to sup- prised of family and trusted friends), country’s brightest young scientists port leading-edge research in the fields Dr. Beckman will continue to be a driv- through the Beckman Young Investiga- of chemistry and the life sciences, ing force in science in the U.S. and, in- tor (BYI) awards. Since 1991, 128 young broadly interpreted, and particularly to deed, the world. faculty have received BYI funding, in- foster the invention of methods, instru- Thank you Dr. Beckman for what cluding our own Dr. Nancy Allbritton, ments and materials that open up new you have done for science in this cen- whose research is featured on page 5. avenues of research and applications tury and for the impact you will have In 1997, the Foundation also initi- in these disciplines and related sci- on science in the next. ated the Beckman Scholars Program to ences.” recognize outstanding undergraduate The disciplines that the Foundation MichaelBerns students in chemistry and biological targets are those around which Dr. sciences. So far, students at 36 univer- Beckman’s company, Beckman Instru- sities have received this award. ments (now Beckman Coulter), flour- Editor’s Note: This tribute to Dr. Beckman The scientists funded through the ished. Chemistry and life sciences tan- was written on April 10, 1999, the occasion Beckman Scholars Program and BYI talized (and still do) his curiosity. It is of his 99th birthday. 3 C L I N I C A L U P D A T E Clinical Advance Speeds Healing ew research by two Beckman effective, Dr. Conn N Laser Institute clinicians may noticed that patients reduce the healing time after full-face who underwent in- laser skin resurfacing and set a new tensive full-face re- standard for treatment.