Bowel Prep with Fleet Enema

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Instructions before Surgery Bowel Preparation for Rectal Surgery / Procedure with Fleet Enema General Instructions: Your surgeon has decided that you should prepare your bowels prior to surgery. The goal of the bowel preparation is to clean your bowel so that stool will not be present that could compromise your scheduled surgery. This will make your surgery safer and reduces the chances of infection and injury to the bowel. In preparation for your rectal surgery/procedure: Purchase over the counter Two (2) Fleet Enemas Eating and drinking the day before your rectal surgery/procedure: 1. Finish eating a regular meal by 6:00 PM the night before your surgery/procedure. After 6:00PM, STOP ALL SOLID FOOD including candy, mints and chewing gum and begin clear liquids. Clear liquids are anything you can hold up to a light and see through. Caffeine and alcohol should be avoided as they can dehydrate you. CLEAR LIQUID DIET-Only these items ARE allowed: a. Water b. Clear broths and bouillon without flecks of meat or vegetables in it c. Clear juices – apple juice, grape juice, cranberry juice d. Clear beverages – 7-up, Sprite, Ginger Ale, Gatorade, Crystal Light, e. Other items – clear Jell-O, popsicles without fruit 2. If you consume any solid food, thick liquids, milk or powdered creamer after 6:00PM the evening before your surgery, your surgery will be cancelled. 3. After MIDNIGHT, water and water ONLY may be consumed up to 3 hours before surgery. Enema administration before your rectal surgery/procedure: An essential part of your preparing for your surgery/procedure is the Fleet enema. You must administer the Fleet enema rectally according to the easy-to-follow instructions that comes with the enema. 1. Administer one enema the evening before your surgery/procedure by 9:00PM. 2. Administer the second enema the morning of your surgery/procedure two (2) hours before leaving for the hospital. THESE ENEMAS ARE ESSENTIAL FOR RECTAL SURGERY/PROCEDURE PREPARATION. For questions or concerns before the day of surgery, please call: Surgery Clinic Department 286 Medical Advice (after hours, weekends, or holidays) Monday – Friday 8:30AM – 5:00PM (408) 554-9800 (408) 851-2000 © 2012 The Permanente Medical Group, Inc. All rights reserved. Santa Clara Health Education. Department of Surgery (Revised 01-12) RL 10.9 .

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Formulation and Characterization of Medicated Chewing Gums of Dextromethorphan Hydrobromide Swamy N.G.N.*, Shilpa P., Abbas Z
FORMULATION AND CHARACTERIZATION OF MEDICATED CHEWING GUMS OF DEXTROMETHORPHAN HYDROBROMIDE Swamy N.G.N.*, Shilpa P., Abbas Z. (Received 01 June 2012) (Accepted 26 November 2012) ABSTRACT Chewing gums are mobile drug delivery systems, with a potential for administering drugs either for local action or for systemic absorption via buccal route. Dextromethorphan hydrobromide chewing gum formulations were made employing Pharmagum M as the base with an aim to overcome the first- pass effect, reducing the risk of overdosing, ease of administration and for achieving faster systemic absorption. Dextromethorphan hydrobromide was further transformed into spray dried form and incorporated into Pharmagum M base with the object of solubility enhancement and masking the bitter taste of the drug. The prepared medicated chewing gums were evaluated for various precompression and postcompression parameters. The in vitro drug release profiles were carried out employing Erweka DRT chewing apparatus. It was observed that increasing the chewing gum base concentration resulted in a decreased drug release profile. The drug in the spray dried form revealed improved performance in comparison to the directly contained drug. The drug release data were fitted into various kinetic models. It was observed that the drug release was matrix diffusion controlled and revealed a non-Fickian drug release mechanism. Accelerated stability studies were carried out on select formulations as per ICH guidelines. The formulations were found to be stable in respect to physical parameters and no significant deviations were seen in respect to in vitro drug release characteristics. Keywords : Medicated Chewing gums, Dextrome- gum formulations have been evaluated for several thorphan hydrobromide, Pharmagum M, Spray drying, drugs including aspirin3, 4, verapamil5, nicotine6, 7, Erweka DRT chewing apparatus miconazole8, nystatin9, chlorhexidine gluconate10, promethazine hydrochloride11 and many more.
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